Journal of Infectious Diseases: Gene expression profiles among Indian children with confirmed TB were distinct from those of adults, highlighting the importance of including distinct populations in differential gene expression models

In this study among people living with HIV, Akshay Gupte and colleagues found that the risk of acquiring tuberculosis was higher in those receiving first-line antiretrovial therapy versus those receiving second-line medications.

International Journal of Tuberculosis and Lung Disease:  Researchers describe the challenges associated with conducting the first randomized clinical trial of antimicrobial agents in pediatric tuberculosis meningitis. 

Infection, Genetics, and Evolution: We investigated the association of TIRAP variants with severity of TB disease and IP-10 production in humans, which may be useful in predicting poor clinical outcome

A suite of mobile health applications shows promise for linking more drug-resisitant TB patients to care and in less time. 

New England Journal of Medicine: Dr. Amita Gupta and colleagues found that the current standard of care given to HIV+ pregnant women to prevent TB should wait until 12 weeks after delivery. The study underscores the need to include pregnant women in clinical trials.

Maunank Shah and colleagues invented HIV-ASSIST, an online decision-making tool that helps clinicians determine what antiretroviral therapies will best meet the needs of individual HIV patients. This paper in JAIDS discusses what they found in testing the tool's validity.