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Larry Chang, MD, MPH
Associate Professor of Infectious Diseases, JHSOM; Associate Professor of International Health, Social and Behavioral Interventions Program, JHBSPH; Associate Professor of Epidemiology, JHBSPH; Associate Director, JHU Global mHealth Initiative
Dr. Larry Chang is Associate Professor of Medicine at the Johns Hopkins University. He is a physician trained in internal medicine, infectious diseases, and epidemiology with an interest in multidisciplinary, innovative, and pragmatic approaches to impacting the HIV/AIDS pandemic. Dr. Chang has experience in HIV treatment and prevention, implementation science, cohort, and mixed methods research. He is currently Co-PI of the Rakai Health Sciences Program (RHSP) in Uganda, and is an active infectious diseases and HIV clinician.
For the past 17 years, Dr. Chang has engaged in HIV-related research in Sub-Saharan Africa. Since 2006, he has worked closely with collaborators from RHSP in Uganda on several randomized and observational studies. In the past, Dr. Chang has had the opportunity to lead with RHSP colleagues several peer and community health worker (CHW)-related implementation science studies including a cluster-randomized study on the impact of peers on AIDS care conducted in 2006-2008 and an individually-randomized study on peer support for pre-ART care in Rakai conducted in 2011-2013. He is currently PI of an R01 evaluating a cluster-randomized trial of a mHealth/CHW approach to combination HIV prevention promotion in a HIV hotspot fishing community in Rakai. In addition to his work with trials, Dr. Chang has also led or supervised several RHSP cohort-based studies, including reports on the heterogeneity of the HIV epidemic in Rakai, and, more recently, on the impact of combination HIV prevention on HIV incidence in the cohort.
Dr. Chang is also involved with HIV implementation science research and capacity building as Director of the Johns Hopkins CFAR Implementation Science Working Group and Director of the Inter-Centers for AIDS Research Sub-Saharan African Working Group (CFAR-SSA). A related focus of Dr. Chang’s research is using mHealth (mobile technologies for health) strategies for improving global public health and clinical care, including novel applications for intimate-partner violence intervention, TB treatment, and HIV care, surveillance, and prevention. Dr. Chang has overseen mHealth projects in Baltimore, Afghanistan, and Uganda. He is the Associate Director for the University-wide Johns Hopkins Global mHealth Initiative. Finally, Dr. Chang has been involved in systematic reviews on topics in HIV as well as on guideline development, working with WHO, IAPAC, and the Cochrane HIV/AIDS group.