Larry Chang, MD, MPH

Baltimore, Maryland
Role: 
Faculty
Associate Professor of Infectious Diseases, JHSOM; Associate Professor of International Health, Social and Behavioral Interventions Program, JHBSPH; Associate Professor of Epidemiology, JHBSPH; Associate Director, JHU Global mHealth Initiative

Dr. Larry Chang is Associate Professor of Medicine, Epidemiology, and International Health at Johns Hopkins University. He is a physician trained in internal medicine, infectious diseases, and epidemiology with an interest in interdisciplinary, innovative, and pragmatic approaches to impacting the HIV pandemic. Dr. Chang has experience in HIV treatment and prevention, implementation science, cohort, community-based trials, and mixed methods research. He is currently Co-PI of the Rakai Health Sciences Program (RHSP) in Uganda and is an active infectious diseases and HIV clinician.

For the past 19 years, Dr. Chang has engaged in HIV-related research in Sub-Saharan Africa. Since 2006, he has worked closely with collaborators from RHSP in Uganda on several randomized and observational studies. In the past, Dr. Chang has had the opportunity to lead with RHSP colleagues several peer and community health worker (CHW)-related implementation science studies including a cluster-randomized study on the impact of peers on AIDS care conducted in 2006-2008 and an individually-randomized study on peer support for pre-ART care in Rakai conducted in 2011-2013. He is currently PI of an R01 evaluating a cluster-randomized trial of a mHealth/CHW approach to combination HIV prevention promotion in a HIV hotspot fishing community in Rakai, PI of an R01 trying to find and evaluate hard-to-reach populations, and Co-PI of a community-randomized trial of a CHW intervention targeting in-migrants. In addition to his work with trials, Dr. Chang has also led or supervised several RHSP cohort-based studies, including reports on the heterogeneity of the HIV epidemic in Rakai, and the impact of combination HIV prevention on HIV incidence in the cohort.

Dr. Chang is also involved with HIV implementation science research and capacity building as a former Director of the Johns Hopkins CFAR Implementation Science Working Group and current Director of the Inter-Centers for AIDS Research Sub-Saharan African Working Group (CFAR-SSA). Dr. Chang is also PI of a Fogarty training grant focused on capacity building to understand and end the HIV epidemic in Uganda. A related focus of Dr. Chang’s research is using mHealth (mobile technologies for health) strategies for improving global public health and clinical care. He is the Associate Director for the University-wide Johns Hopkins Global mHealth Initiative.

Research Program Building and Leadership

  • 2000-present: Member, International AIDS Society (IAS)
  • 2006-present: Member, Infectious Diseases Society of America (IDSA)
  • 2010-present: Interviewer, Johns Hopkins Infectious Diseases Fellowship Program 
  • 2011-present: Member, International Association of Physicians in AIDS Care (IAPAC)
  • 2014: Member, Johns Hopkins Department of International Health Faculty Search Committee
  • 2018: Member, Division of Infectious Diseases Faculty Representative Panel, Department of Medicine Departmental Review
  • 2018: Member, Johns Hopkins Department of International Health Faculty Search Committee

Hard-to-Reach Populations: Implications for Ending the AIDS Epidemic

Post Date: 
2019-04-25
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Countries: 
The Rakai region in Uganda was the initial epicenter of the HIV epidemic in East Africa and continues to be a high burden area, with an HIV prevalence of ~13%. Through the open, population-based Rakai Community Cohort Study (RCCS), we reported that combination HIV prevention (CHP) decreased...

Evaluation of National Video Directly Observed Therapy Implementation

Post Date: 
2018-08-05
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Countries: 
emocha Mobile Health, Inc., and Johns Hopkins investigators have developed a user-friendly, HIPAA compliant application for asynchronous video directly observed therapy (DOT) miDOT. The miDOT platform consists of a patient-facing mobile application where patients can record videos of themselves...

RCT to Reduce HIV Acquisition and Viral Load among Migrants, Rakai, Uganda

Post Date: 
2018-08-01
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Countries: 
The Rakai Health Sciences Program (RHSP), Uganda, proposes an implementation science community- randomized controlled trial (CRCT) of a novel intervention to newly in-migrated individuals (Welcome In-coming Neighbor [WIN]), to optimize their rapid linkage to combination HIV prevention (CHP)...

Multidisciplinary Research Training to Understand and Reduce HIV Incidence in Uganda

Post Date: 
2018-05-10
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Countries: 
Dr. Larry Chang is PI for this multi-year (2018-2023) training grant sponsored by the Fogarty International Center at the National Institute of Health. Abstract While substantial progress has been made in the global HIV response, impact has been uneven. Uganda provides a prime case study. Uganda...

miDOT (Directly Observed Therapy)

Post Date: 
2015-11-01
Designed by Dr. Maunank Shah, the miDOT mobile health application is a video-based Directly Observed Therapy interface that uses the emocha Mobile Health platform to remotely connect patients on long-term tuberculosis therapy with clinicians who are required to witness patients taking...

Community Health Workers, mHealth, and Combination HIV Prevention in a Hotspot: A Randomized Trial (mLAKE)

Post Date: 
2015-04-01
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Countries: 
Led by Dr. Larry Chang, the mLAKE study in Uganda is examining whether community health workers equipped with cellphones and the emocha Mobile Health platform are able to successfully promote HIV treatment and prevention services in households in a fishing community in East Africa with a very high...

Project S.O.A.R. (Supporting Operational AIDS Research): Positive Health Dignity and Prevention Sub-Project

Post Date: 
2014-09-15
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Countries: 
Dr. Larry Chang is a Co-Investigator for this effort. Purpose The goal of Project SOAR (Supporting Operational AIDS Research) is to improve the quality and impact of HIV and AIDS program outcomes by strengthening operations research and evaluation activities. Project SOAR supports the PEPFAR...

Evaluating Demand Generation (Stylish Man) for HIV/Family Planning Services, Rakai, Uganda

Post Date: 
2014-08-01
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Countries: 
Dr. Larry Chang is co-investigator of this effort to test a novel approach to promoting HIV services in Rakai, Uganda. The Stylish Man Program, attempts to “demedicalize” HIV prevention and care in a public health campaign designed to normalize HIV care as part of self care for African men. The...

Community Home Based India Prevention of Mother to Child Transmission of HIV (COMBIND)

Post Date: 
2013-09-02
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Countries: 
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Clinical Sites: 
This study ended May 14, 2019. CCGHE is assessing whether equipping Community Health Workers with mobile health technology and involving them in technology training and personal empowerment seminars can help prevent mother-to-child transmission of HIV. CHWs who care for HIV + pregnant and nursing...

Feasibility and Acceptability of Smartphone-Based Ecological Momentary Assessment of Alcohol Use Among African American Men Who Have Sex With Men in Baltimore

Post Date: 
2013-01-01
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Countries: 
This study provides evidence to support the feasibility and acceptability of using Ecological Momentary Assessment (EMA ) methods for collecting data on alcohol use among African American men who have sex with men living in urban settings. These data provide the basis for future studies of EMA-...

ONCOGRID: An mHealth Approach to Prevention and Early Diagnosis of Oral Cancer in Rural South India

Post Date: 
2012-11-01
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Countries: 
This study ended February 7, 2017. The Indian sub-continent is burdened with 80% of the world’s patients with oral cancer, and delay in oral cancer diagnosis is one of the major problems that leads to poor treatment outcomes (V. Shanta, R. Swaminathan, R. Rama. Cancer Control 2013). Current...

Analysis of Data Collected from the Evaluation of Community-Based Education, Research and Service (COBERS)

Post Date: 
2012-06-12
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Countries: 
This effort ended in June 2015. Makerere University College of Health Sciences (MakCHS), the Medical Schools at Gulu University (GU), Mbarara University of Science and Technology (MUST), Kampala International University (KIU) and Busitema University (BU) came together with Johns Hopkins University...

DOmestic Violence Enhanced Home Visitation and Smart Phones (DOVE)

Post Date: 
2012-01-01
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Countries: 
This effort ended in 2017. The major challenge of early prenatal nurse home visitation programs is to accurately identify abused women. The DOVE study aims to improve maternal health and increase the use of a safety plan and community resources by using an emocha ® application to assist home...

PreventionRx Study: Home-based Counseling and Testing in Uganda

Post Date: 
2010-10-21
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Countries: 
This study was terminated August 29, 2014. A ‘platform’ for evaluating combination HIV prevention & care-HIV counseling & testing is essential to optimize HIV services. In collaboration with the University of Washington and the Integrated Community Based Initiatives (ICOBI) NGO in Uganda,...

Peer Community-based Assistant in REtention: Effect of Peer Health Workers on People Living with HIV Not on Antiretroviral Therapy—A Randomized Operations Research Trial

Post Date: 
2007-03-29
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Countries: 
Human resource limitations, long travel times, and a weak health care infrastructure pose significant challenges to the delivery of anti-retroviral therapy (ART) in rural settings such as the Rakai District in southwestern Uganda. HIV increases demand for health services and also impacts the health...

Quantifying HIV transmission flow between high-prevalence hotspots and surrounding communities: a population-based study in Rakai, Uganda

Post Date: 
2020-03-17
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Countries: 
Publication: 
The Lancet HIV
BACKGROUND: International and global organisations advocate targeting interventions to areas of high HIV prevalence (ie, hotspots). To better understand the potential benefits of geo-targeted control, we assessed the extent to which HIV hotspots along Lake Victoria sustain transmission in...

Migration, hotspots, and dispersal of HIV infection in Rakai, Uganda

Post Date: 
2020-02-20
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Countries: 
Publication: 
Nature Communications
Abstract HIV prevalence varies markedly throughout Africa, and it is often presumed areas of higher HIV prevalence (i.e., hotspots) serve as sources of infection to neighboring areas of lower prevalence. However, the small-scale geography of migration networks and movement of HIV-positive...

Impact of combination HIV interventions on HIV incidence in hyperendemic fishing communities in Uganda: a prospective cohort study

Post Date: 
2019-10-06
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Countries: 
Publication: 
The Lancet HIV
BACKGROUND: Targeting combination HIV interventions to locations and populations with high HIV burden is a global priority, but the impact of these strategies on HIV incidence is unclear. We assessed the impact of combination HIV interventions on HIV incidence in four HIV-hyperendemic communities...

Adaptive viral load monitoring frequency to facilitate differentiated care: a modeling study from Rakai, Uganda

Post Date: 
2019-09-18
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Countries: 
Publication: 
Clinical Infectious Diseases
INTRODUCTION: After scaleup of antiretroviral therapy (ART), routine annual viral load monitoring has been adopted by most countries, but reduced frequency of viral load monitoring may offer cost savings in resource limited settings. We investigated if viral load monitoring frequency could be...

Cell Phones, Sexual Behaviors and HIV Prevalence in Rakai, Uganda: A Cross Sectional Analysis of Longitudinal Data

Post Date: 
2019-09-13
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Countries: 
Publication: 
AIDS and Behavior
Abstract Cell phones have increased communication and connection across the globe and particularly in sub-Saharan Africa-with potential consequences for the HIV epidemic. We examined the association among ownership of cell phones, sexual behaviors (number of sexual partners, alcohol use before sex...

Evaluation of miLINC to shorten time to treatment for rifampicin-resistant Mycobacterium tuberculosis

Post Date: 
2019-09-01
Publication: 
The International Journal of Tuberculosis and Lung Disease
A suite of mobile health applications shows promise for linking more drug-resisitant TB patients to care and in less time.

Community-Driven Priorities in Smartphone Application Development: Leveraging Social Networks to Self-Manage Type 2 Diabetes in a Low-Income African American Neighborhood

Post Date: 
2019-07-30
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Countries: 
Publication: 
International Journal of Environmental Research and Public Health
Social networks have the potential to enhance Type 2 Diabetes Mellitus (T2DM) self-management. We used qualitative methods to study if and how mobile application (app) functions that mobilize social resources to improve T2DM management would be desired in a low-income African American community. Data were collected through community discussions and in-depth interviews with 78 participants in 2016–2018.

Geographic Information Systems, spatial analysis, and HIV in Africa: A scoping review

Post Date: 
2019-03-03
Publication: 
PLoS One
Geographic Information Systems (GIS) and spatial analysis are emerging tools for global health, but it is unclear to what extent they have been applied to HIV research in Africa. To help inform researchers and program implementers, this scoping review documents the range and depth of published HIV-related GIS and spatial analysis research studies conducted in Africa.

Results of early virologic monitoring may facilitate differentiated care monitoring strategies for clients on ART, Rakai, Uganda

Post Date: 
2018-10-15
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Countries: 
Publication: 
Open Forum Infectious Diseases
BACKGROUND: Viral load (VL) monitoring is standard of care in HIV-infected persons initiated on antiretroviral therapy (ART). We evaluated the predictive value of VL measurements at 6 and 12 months after initiation of firstline ART to estimate the future risk of virologic failure (VF). METHODS: HIV...

Using mHealth to improve tuberculosis case identification and treatment initiation in South Africa: Results from a pilot study

Post Date: 
2018-07-03
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Countries: 
Publication: 
PLoS One
BACKGROUND: Tuberculosis (TB) incidence in South Africa is among the highest globally. Initial loss to follow-up (ILFU), defined as not starting on TB treatment within 28 days of testing positive, is undermining control efforts. We assessed the feasibility, acceptability, and potential of a mHealth...

Migration and risk of HIV acquisition in Rakai, Uganda: a population-based cohort study

Post Date: 
2018-04-15
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Countries: 
Publication: 
Lancet HIV
BACKGROUND: In sub-Saharan Africa, migrants typically have higher HIV prevalence than non-migrants; however, whether HIV acquisition typically precedes or follows migration is unknown. We aimed to investigate the risk of HIV after migration in Rakai District, Uganda. METHODS: In a prospective...

HIV viral suppression and geospatial patterns of HIV antiretroviral therapy treatment facility use in Rakai, Uganda

Post Date: 
2018-03-27
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Countries: 
Publication: 
AIDS
OBJECTIVE: To assess geospatial patterns of HIV antiretroviral therapy (ART) treatment facility use and whether they were impacted by viral load suppression. METHODS: We extracted data on the location and type of care services utilized by HIV-positive persons accessing ART between February 2015 and...

The validity of self-reported antiretroviral use in persons living with HIV: a population-based study

Post Date: 
2018-01-28
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Countries: 
Publication: 
AIDS
OBJECTIVE: To assess the validity of self-reported antiretroviral therapy use (ART) using population-based cohort data. METHODS: Self-reported ART use and nonuse was compared with a validated laboratory assay in 557 HIV-positive participants in the Rakai Community Cohort Study surveyed between...

Identifying models of HIV care and treatment service delivery in Tanzania, Uganda, and Zambia using cluster analysis and Delphi survey

Post Date: 
2017-12-06
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Countries: 
Publication: 
BMC Health Services Research
BACKGROUND: Organization of HIV care and treatment services, including clinic staffing and services, may shape clinical and financial outcomes, yet there has been little attempt to describe different models of HIV care in sub-Saharan Africa (SSA). Information about the relative benefits and...

HIV prevention efforts and incidence in HIV in Uganda

Post Date: 
2017-11-30
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Countries: 
Publication: 
New England Journal of Medicine
In a large study in Uganda, Dr. Larry Chang and colleagues found that combination HIV prevention has population level implications, reducing new infections by 42%.

Impact of a community health worker HIV treatment and prevention intervention in an HIV hotspot fishing community in Rakai, Uganda (mLAKE): study protocol for a randomized controlled trial

Post Date: 
2017-10-23
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Countries: 
Publication: 
Trials
Abstract Background: Effective yet practical strategies are needed to increase engagement in HIV treatment and prevention services, particularly in high-HIV-prevalence hotspots. We designed a community-based intervention called "Health Scouts" to promote uptake and adherence to HIV services in a...

Design and implementation of a community health worker HIV treatment and prevention intervention in an HIV hot spot fishing community in Rakai, Uganda

Post Date: 
2017-05-22
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Countries: 
Publication: 
Journal of the International Association of Providers of AIDS Care
Abstract Innovative approaches are needed to increase engagement in HIV treatment and prevention services, particularly in HIV hot spots. Here, we detail our design, training approach, and early implementation experiences of a community-based HIV intervention called "health scouts." The...

Qualitative insights into implementation, processes, and outcomes of a randomized trial on peer support and HIV care engagement in Rakai, Uganda

Post Date: 
2017-01-10
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Countries: 
Publication: 
BMC Infectious Diseases
BACKGROUND: People living with human immunodeficiency virus (HIV) who have not yet initiated antiretroviral therapy (ART) can benefit from being engaged in care and utilizing preventive interventions. Community-based peer support may be an effective approach to promote these important HIV services...

Heterogeneity of the HIV epidemic in agrarian, trading, and fishing communities in Rakai, Uganda: an observational epidemiological study

Post Date: 
2016-08-15
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Countries: 
Publication: 
The Lancet HIV
Background : Understanding the extent to which HIV burden differs across communities and the drivers of local disparities is crucial for an effective and targeted HIV response. We assessed community-level variations in HIV prevalence, risk factors, and treatment and prevention service uptake in...

Community-based interventions to improve and sustain antiretroviral therapy adherence, retention in HIV care and clinical outcomes in low- and middle-income countries for achieving the UNAIDS 90-90-90 targets

Post Date: 
2016-07-30
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Countries: 
Publication: 
Current HIV/AIDS Reports
Little is known about the effect of community versus health facility-based interventions to improve and sustain antiretroviral therapy (ART) adherence, virologic suppression, and retention in care among HIV-infected individuals in low- and middle-income countries (LMICs). We systematically searched...

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Rapidly declining HIV incidence among men and women in Rakai, Uganda

Post Date: 
2020-03-11
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Countries: 
Nakigozi G , Chang LW, Reynolds SJ, Nalugoda F, Kigozi G, Quinn TC, Gray RH, Kisakye A, Ndyanabo A, Ssekubugu R, Serwadda D, Wawer M, Kayaayi J, Grabowski MK, for the Rakai Health Sciences Program. Rapidly declining HIV incidence among men and women in Rakai, Uganda. Presented at: CROI 2020. Boston...

Trends in linkage into care after “Test and Start” among adolescents and young adults

Post Date: 
2020-03-11
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Countries: 
Kigozi DS , Kreniske P, Chen I, Nalugoda F, Hoffman S, Kigozi G, Nakigozi G, Ssekubugu R, Kankaka E, Gray RH, Wawer M, Chang LW, Reynolds SJ, Lualo T, Kagaayi J. Trends in linkage into care after “Test and Start” among adolescents and young adults. Presented at: CROI 2020. Boston, MA; March 8-11,...

Indeterminate HIV rapid-test results: Outcomes and risk factors

Post Date: 
2020-03-10
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Countries: 
Mwinnyaa G , Grabkowski MK, Gray RH, Wawer M, Chang LW, Ssekasanvu J, Kagaayi J, Kigozi G, Galiwango RM, Ndyanabo A, Serwadda D, Quinn TC, Reynolds SJ, Laeyendecker O for the Rakai Community Cohort Study. Indeterminate HIV rapid-test results: Outcomes and risk factors. Presented at: CROI 2020...

Long-term effectiveness of voluntary medical male circumcision for HIV prevention

Post Date: 
2020-03-10
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Countries: 
Loevinsohn G , Kigozi G, Kagaayi J, Nalugoda F, Chang LW, Serwadda D, Reynolds SJ, Nakigozi G, Ssekubugu R, Wawer M, Tobian A, Gray RH, Grabowski MK for the Rakai Sciences Program. Long-term effectiveness of voluntary medical male circumcision for HIV prevention. Presented at: CROI 2020. Boston, MA...

“Stylish Man” cluster RCT to increase male circumcision for adult men ≥ 19, Uganda

Post Date: 
2020-03-10
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Countries: 
Wawer M , Kigozi G, Mugamba S, Zikusooka A, Kagaayi J, Serwadda D, Ndyanabo A, Ssekubugu R, Sseasanvu J, Chang LW, Gray RH. “Stylish Man” cluster RCT to increase male circumcision for adult men ≥ 19, Uganda. Presented at: CROI 2020. Boston, MA; March 8-11, 2020.

An mHealth CHW intervention trials in an HIV hyperendemic community in Rakai, Uganda

Post Date: 
2020-03-09
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Countries: 
Chang LW , Mbabali I, Kong X, Amico R, Kennedy CE, Nalugoda F, Anok A, Serwadda D, Ssekasanvu J, Quinn TC, Reynolds SJ, Gray RH, Wawer M, Hutton H, Nakigozi G. An mHealth CHW intervention trials in an HIV hyperendemic community in Rakai, Uganda. Presented at: CROI 2020. Boston, MA; March 8-11, 2020.

Population-level HIV viral load varies by gender, age, and location in Rakai, Uganda

Post Date: 
2020-03-09
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Countries: 
Kyle I , Kagaagi J, Kigozi G, Nakigozi G, Ssekbugu R, Nalugoda F, Grabowski MK, Chang LW, Wawer M, Serwadda D, Gray RH, Quinn T, Reynolds SJ, Rattman O for the Rakai Health Sciences Program. Population-level HIV viral load varies by gender, age, and location in Rakai, Uganda. Presented at: CROI...

Waxing and waning HIV risk: Dynamics of PrEP eligibility in Rakai, Uganda

Post Date: 
2020-03-09
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Countries: 
Ssempijja V, Ssekubugu R, Kigozi G, Kakigozi G, Kagaayi J, Lutalo T, Ndyanabo A, Ekstrom AM, Serwadda D, Quinn TC, Gray RH, Wawer M, Chang LW, Reynolds SJ. Waxing and waning HIV risk: Dynamics of PrEP eligibility in Rakai, Uganda. Presented at: CROI 2020. Boston, MA; March 8-11, 2020.

mobile Health (mHealth) strategies to strengthen CHW impact.

Post Date: 
2019-09-16
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Countries: 
Chang L. mobile Health (mHealth) strategies to strengthen CHW impact. Strengthening the Impact of Community Health Workers on HIV Care and Viral Suppression in the US. Bethesda, MD. September 16, 2019.

Mobile health technologies to improve the HIV cascade in India: Opportunities & considerations

Post Date: 
2019-09-06
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Countries: 
Chang L. Mobile health technologies to improve the HIV cascade in India: Opportunities & considerations. Invited Speaker. National Consultation on Global & Local Evidence to Improve the HIV Cascade in India. Dehli, India; September 6, 2019.

Global HIV update

Post Date: 
2019-04-29
Chang L. Global HIV update. Invited Speaker. 29th Annual Clinical Care of the Patient with HIV Infection and Care of Patient with Viral Hepatitis. Baltimore, MD; April 29, 2019.

The Rakai Health Sciences Program: 30 Years of HIV multidisciplinary research, lessons learned, future directions

Post Date: 
2019-03-19
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Countries: 
Chang L.The Rakai Health Sciences Program: 30 years of HIV multidisciplinary research, lessons learned, future directions. Invited Speaker. HIV Grand Rounds. University of Pennsylvania. Philadelphia, PA; March 21, 2019.

mHealth in medicine: A Hopkins-Focused Perspective

Post Date: 
2017-02-24
Chang, L. mHealth in medicine: A Hopkins-Focused Perspective. Digital Health Day. Johns Hopkins University. Baltimore, MD.

A Cluster-Randomized Trial to Promote Combination HIV Prevention Using M-health-Supported CHWs in a High-Prevalence Fishing Community: Design and Baseline Characteristics of the mLAKE Trial in Rakai, Uganda

Post Date: 
2016-07-21
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Countries: 
Chang L, Mbabali I, Kong X, Hutton H, Long A, Thomas A, Bugos E, Ssekasanvu J, Kennedy C, Amico R, Nalugoda F, Reynolds S, Quinn T, Serwadda D, Wawer M, Gray R, Nakigozi G. A Cluster-Randomized Trial to Promote Combination HIV Prevention Using M-health-Supported CHWs in a High-Prevalence Fishing...

Migration, HIV Infection, and Combination HIV Prevention Access in Rakai, Uganda

Post Date: 
2016-02-23
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Countries: 
Grabowski MK, Lessler J, Bazaale JM, Chang L, Nabukalu D, Wawer M, Nalugoda F, Ssekubugu R, Nakigozi G, Gray RH. Migration, HIV Infection, and Combination HIV Prevention Access in Rakai, Uganda. Conference on Retroviruses and Opportunistic Infections 2016. Boston, MA. 2016.

Combination HIV Prevention and HIV Incidence in a Ugandan Hotspot Fishing Community

Post Date: 
2016-02-23
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Countries: 
Kagaayi J, Grabowski MK, Nakigozi G, Kigozi G, Nalugoda F, Ssekubugu R, Gray RH, Serwadda D, Wawer MJ, Chang L. Combination HIV Prevention and HIV Incidence in a Ugandan Hotspot Fishing Community. Conference on Retroviruses and Opportunistic Infections 2016. Boston, MA. 2016.

Applied HIV Epidemiology and Implementation Science: a multidisciplinary approach to understanding and controlling an evolving epidemic

Post Date: 
2015-11-20
Chang, L. Applied HIV Epidemiology and Implementation Science: a multidisciplinary approach to understanding and controlling an evolving epidemic. National Institutes of Health. Bethesda, MD.

Rakai Health Sciences Program: Social, Behavioral, and Biomedical Research in HIV Dynamics, Prevention, and Care

Post Date: 
2015-10-30
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Countries: 
Chang, L. Rakai Health Sciences Program: Social, Behavioral, and Biomedical Research in HIV Dynamics, Prevention, and Care. CFAR National Social and Behavioral Sciences Research Network Annual Meeting. Baltimore, MD.

mHealth

Post Date: 
2015-10-29
Chang, L. mHealth. CFAR National Social and Behavioral Sciences Research Network Annual Meeting. Baltimore, MD.

Intro to mHealth

Post Date: 
2014-12-17
Change, L. Intro to mHealth. JHU-GmI Seminar. Johns Hopkins School of Medicine. Baltimore, MD.

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Martha Kirabo, MBChB

Uganda Fogarty Scholar
Dr Martha Kirabo
Dr Martha Kirabo is a medical doctor from Uganda. She earned her MBChB from Makerere University. A Fogarty fellow, she is undertaking Master of Public Health training at the Johns Hopkins Bloomberg School of Public Health. Prior to JHSPH, she practiced as a clinical research doctor at the Uganda Case Western Reserve University Research Collaboration in Kampala, working in the Clinical trials department as a safety and pharmacovigilance officer. She is interested in attaining skills in epidemiological and biostatistical methods in public health and clinical research, infectious disease...

Alvin Thomas, MSPH

Baltimore, Maryland
Alvin Thomas
Alvin Thomas graduated from the Johns Hopkins Bloomberg School of Public Health in 2016 with an MSPH in international health. Under the guidance of CCGHE's Dr. Larry Chang, Alvin worked with the mLAKE (Lakefolk Actively Keeping Engaged) and EMAI Rakai (Ecological Momentary Analysis and Intervention) studies in Uganda. Both studies are a partnership with the Rakai Health Science Program (RHSP) and use software developed by the award-winning emocha mobile health platform (http://www.emocha.com). The mLAKE intervention trains community health workers to deliver...

Eva Bugos, MSPH

Baltimore, Maryland
Eva Bugos
Eva Bugos graduated from Johns Hopkins Bloomberg School of Public Health in 2016 with an MSPH in population, family and reproductive health Eva worked with Dr. Larry Chang on the mLAKE (Lakefolk Actively Keeping Engaged) and EMAI-Rakai (Ecological Momentary Analysis and Intervention) studies in Uganda. Both are mHealth studies conducted in partnership with the Rakai Health Sciences Program in Rakai, Uganda. The mLAKE study is a cluster-randomized intervention that trains community health workers to provide counseling to promote uptake of HIV services. The EMAI study is assessing the use of...

Amanda Long, MSPH

Baltimore, Maryland
Amanda Long graduated from the Johns Hopkins Bloomberg School of Public Health in May 2016 with an MSPH in international health. She worked with Dr. Larry Chang on a mHealth and HIV counseling study in Rakai, Uganda. She traveled to Uganda from July to November 2015 to help kick off the study, titled mLAKE (Lakefolk Actively Keeping Engaged). Her role included community sensitization of the study, Community Health Worker (CHW) recruitment and training, and process evaluations to assess study progress and CHW performance. She also assisted with monitoring CHW performance and other program...

Kristin Thomas

Baltimore, Maryland
Kristin Thomas
Kristin Thomas is a MSPH candidate at the Johns Hopkins Bloomberg School of Public Health studying social and behavioral interventions in international health. She specializes in mHealth, qualitative research methods, and health communications. Ms. Thomas joined Dr. Larry Chang’s mLAKE study in Spring 2015 and traveled to Rakai District, Uganda during the summer to join the team at the Rakai Health Sciences Program (RHSP). RHSP is a leader in HIV/AIDS research in Uganda. The mLAKE study seeks to determine the feasibility, acceptability, and impact of an mHealth-guided HIV counseling...

$17M is awarded to support HIV, disease ecology, mHealth projects

Post Date: 
2018-08-16
Source: 
Global Health Matters
NIH Fogarty International Center Logo
Larry Chang's Multidisciplinary Research Training to Understand and Reduce HIV Incidence in Uganda is among the funded projects.

TB medication adherence rates up, thanks to smartphone app

Post Date: 
2018-03-02
Source: 
YourCentralValley.com (Fresno, CA)
Emocha's app is helping tuberculosis patients in Fresno County stick to their treatment plans.

Notes from the Field: Use of Asynchronous Video Directly Observed Therapy for Treatment of Tuberculosis and Latent Tuberculosis Infection in a Long-Term–Care Facility ― Puerto Rico, 2016–2017

Post Date: 
2017-12-22
Source: 
Morbidity and Mortality Weekly Report
emocha's video Directly Observed Therapy is highlighted in this report.

Notes from the Field--Tuberculosis Control Activities After Hurricane Harvey--Texas, 2017

Post Date: 
2017-12-15
Source: 
Morbidity and Mortality Weekly Report
emocha's video Directly Observed Therapy helped officials maintain continuity of care for TB patients following Hurricane Harvey.

Combination HIV prevention reduces infections

Post Date: 
2017-12-01
Source: 
MD Magazine
. . . Researchers found that throughout the 7-year period in which rates of treatment and voluntary medical male circumcision increased significantly, HIV incidence dropped by 42% among nearly 18,000 people in Uganda . . .

NIH Statement on World AIDS Day 2017

Post Date: 
2017-12-01
. . . A study published recently in the New England Journal of Medicine found that HIV incidence dropped by 42 percent among nearly 18,000 people in a Ugandan district during a 7-year period when the rates of HIV treatment and voluntary medical male circumcision were significantly increased . . .

Combination HIV Prevention Reduces New Infections by 42 Percent in Ugandan District

Post Date: 
2017-11-29
NIH announces findings from Larry Chang and colleagues published in the New England Journal of Medicine .

Male Circumcision and Antiviral Drugs Appear to Sharply Reduce HIV Infection Rate

Post Date: 
2017-11-29
. . . The study, published Nov. 29 in the New England Journal of Medicine , is the first to track a large group of people before, during and after the start of an HIV prevention program and show that the program is likely working on a large scale. The researchers found that as the program began and...

Male circumcision and antiviral drugs appear to sharply reduce HIV infection rate

Post Date: 
2017-11-29
Source: 
Medical Xpress
. . . The current study, based on RCCS data on 34,000 adults enrolled and followed between 1989 and 2016, confirmed the widespread adoption of many of PEPFAR's HIV prevention measures. The use of antiretroviral therapy among infected people rose steadily from 12 percent in the 2006 survey to 69...

Emocha Mobile Health expands to opioid addiction treatment

Post Date: 
2017-06-23
Source: 
Baltimore Sun
Baltimore Sun: emocha received award to expand miDOT capabilities to help care providers treat opioid addiction.

emocha is looking to help treat opioid addiction

Post Date: 
2017-06-16
Source: 
Technical.ly Baltimore
emocha received a $1.7 million grant from the National Institute on Drug Abuse to complete the research studies ahead of its commercial release. The technology will be used in clinic-based treatment, with observation of take-home being a next step. The grant will help the startup validate the...

Emocha launches pilot to help recovering opioid addicts

Post Date: 
2017-06-15
Source: 
Baltimore Business Journal
Emocha will be piloting its platform in partnership with two opioid recovery clinics based at the University of Washington in Seattle and Boston University.

Company tests mobile health for tuberculosis treatment

Post Date: 
2017-05-23
Source: 
NIH: News and Events
Preliminary data show 93% treatment adherence using video observation, with savings of more than $1,000 per TB patient over 6 months

emocha and miDiagnostics collaborate to achieve more comprehensive mobile testing

Post Date: 
2016-12-12
Source: 
iMedicalApps
Baltimore-based tech startup emocha is collaborating with miDIAGNOSTICS in order to combine hardware and software to augment current medical tests for patients and health care providers. Emocha is a Johns Hopkins startup spinout and the end goal is to utilize each company’s strengths to bring test...

Mobile Technology Developed at Hopkins Medicine Transforming TB Care in Texas

Post Date: 
2016-04-19
Harris County Public Health Environmental Services Hailed TB Elimination Champion by CDC The US Centers for Disease Control and Prevention recently named Harris County Public Health Environmental Services among its 2016 TB Elimination Champions for...

Dr. Larry Chang Promoted to Associate Professor

Post Date: 
2015-12-16
Baltimore, MD—The Division of Infectious Diseases at Johns Hopkins Medicine announced yesterday the promotion of Larry William Chang, MD, MPH, to Associate Professor of Medicine. Dr. Chang is a member of the faculty at the Johns Hopkins Center for Clinical Global Health Education (CCGHE), and a...

Amid international growth, emocha gets grant to look at Maryland TB treatment

Post Date: 
2015-11-23
Source: 
Technical.ly Baltimore
emocha Mobile Health received a Small Business Innovation Research grant to further development of its mobile app that provides video-based healthcare observations in some cases where visits were previously required. The NIH grant, which is for about $200,000 over two years, will allow the Johns...

emocha App for Ebola Monitoring Nominated for Innovation Award

Post Date: 
2015-08-28
emocha ® Mobile Health, Inc., was nominated this week for a 2015 Baltimore Innovation Award for its Outbreak Symptoms Monitoring Application developed to monitor symptoms among people traveling from west-African countries where there are active Ebola outbreaks. emocha ® is one of 5 companies...

Sparking change: Baltimore's growing startup community

Post Date: 
2015-08-04
Source: 
Baltimore Fishbowl
Baltimore is kind of like a small-scale America, gearing towards a service-based economy for a variety of industries, with the startups here are trying to reinvigorate the economy on both a macro and a micro level. emocha, a health IT startup developed by the Johns Hopkins Center for Clinical...

Mobile app developed by JHU grads helps monitor Ebola, tuberculosis patients

Post Date: 
2015-05-13
Source: 
The HUB at Johns Hopkins
Listening to Morad Elmi list off the recent developments at emocha Mobile Health Inc., the company he co-founded with fellow Johns Hopkins Carey Business School graduate Sebastian Seiguer, it's hard not to be impressed by the breadth and scope of the startup's work. In the past six months, the...

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