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Larry Chang, MD, MPH
Associate Professor of Infectious Diseases, JHSOM; Associate Professor of International Health, Social and Behavioral Interventions Program, JHBSPH; Associate Professor of Epidemiology, JHBSPH; Associate Director, JHU Global mHealth Initiative
Dr. Larry Chang is Associate Professor of Medicine, Epidemiology, and International Health at Johns Hopkins University. He is a physician trained in internal medicine, infectious diseases, and epidemiology with an interest in interdisciplinary, innovative, and pragmatic approaches to impacting the HIV pandemic. Dr. Chang has experience in HIV treatment and prevention, implementation science, cohort, community-based trials, and mixed methods research. He is currently Co-PI of the Rakai Health Sciences Program (RHSP) in Uganda and is an active infectious diseases and HIV clinician. For the past 20 years, Dr. Chang has engaged in HIV-related research in Sub-Saharan Africa. Since 2006, he has worked closely with collaborators from RHSP in Uganda on several randomized and observational studies.
In the past, Dr. Chang has had the opportunity to lead with RHSP colleagues several peer and community health worker (CHW)-related implementation science studies including a cluster-randomized study on the impact of peers on AIDS care conducted in 2006-2008, an individually-randomized study on peer support for pre-ART care in Rakai conducted in 2011-2013, and a cluster-randomized trial of a mHealth/CHW approach to HIV treatment and prevention service promotion in an HIV hotspot fishing community. Dr. Chang is currently PI of a large study of the urbanization, non-communicable disease, and HIV syndemic in Uganda, PI of a study trying to find and evaluate hard-to-reach populations in Uganda, and Co-PI of a community-randomized trial of a CHW intervention targeting in-migrants.
In addition to his work with trials, Dr. Chang has also led or supervised several RHSP cohort-based studies, including reports on the heterogeneity of the HIV epidemic in Rakai, and the impact of combination HIV prevention on HIV incidence in the cohort. In Baltimore, Dr. Chang is Co-PI of a trial studying the impact of leveraging patient supporters and a smartphone app to promote engagement in HIV care. Dr. Chang is also involved with HIV implementation science research and capacity building as a former Director of the Johns Hopkins CFAR Implementation Science Working Group and current Director of the Inter-Centers for AIDS Research Sub-Saharan African Working Group (CFAR-SSA). Dr. Chang is also PI of a Fogarty training grant focused on capacity building to understand and end the HIV epidemic in Uganda. A related focus of Dr. Chang’s research is using mHealth (mobile technologies for health) strategies for improving global public health and clinical care. He is the Associate Director for the University-wide Johns Hopkins Global mHealth Initiative. As part of the COVID-19 response, Dr. Chang is a member of the Johns Hopkins COVID-19 Treatment Guidance Writing Group, Pharmaceutical Lead for the Johns Hopkins 2019 Novel Coronavirus Research Compendium (NCRC), and member of the Johns Hopkins Community Collaboration to Combat Coronavirus scientific steering committee.
- Research Program Building and Leadership
- 2000-present: Member, International AIDS Society (IAS)
- 2006-present: Member, Infectious Diseases Society of America (IDSA)
- 2010-present: Interviewer, Johns Hopkins Infectious Diseases Fellowship Program
- 2014, 2018: Member, Johns Hopkins Department of International Health Faculty Search Committee
- 2018: Member, Division of Infectious Diseases Faculty Representative Panel, Department of Medicine Departmental Review