Study/Projects - HIV

P1078: A Phase IV Randomized Double-Blind Placebo-Controlled Trial to Evaluate the Safety of Immediate (Antepartum-Initiated) Versus Deferred (Postpartum-Initiated) Isoniazid Preventive Therapy Among HIV-Infected Women in High TB Incidence Settings

Post Date: 
2014-04-01
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This is a clinical trial conducted under the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Network and funded by the U.S. National Institutes of Health. Dr. Amita Gupta is Protocol Chair for this multinational clinical trial being conducted in...

Evaluation of HIV Disease Burden in Hospitalized Patients at Sassoon General Hospital in Pune, India

Post Date: 
2013-11-18
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This study was terminated September 13, 2005. The goal of this project was to conduct both a retrospective and prospective epidemiological study of the burden of HIV disease at Sassoon General Hospital. The specific objectives of the study were to establish the proportion of HIV-infected...

Community Home Based India Prevention of Mother to Child Transmission of HIV (COMBIND)

Post Date: 
2013-09-02
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This study ended May 14, 2019. CCGHE is assessing whether equipping Community Health Workers with mobile health technology and involving them in technology training and personal empowerment seminars can help prevent mother-to-child...

Feasibility and Acceptability of Smartphone-Based Ecological Momentary Assessment of Alcohol Use Among African American Men Who Have Sex With Men in Baltimore

Post Date: 
2013-01-01
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This study provides evidence to support the feasibility and acceptability of using Ecological Momentary Assessment (EMA ) methods for collecting data on alcohol use among African American men who have sex with men living in urban settings. These data provide the basis for future studies of EMA-...

Project Connect Baltimore: Connecting Young Males to Sexual/Reproductive Healthcare

Post Date: 
2012-10-01
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To design, implement and evaluate a male-friendly and culturally appropriate guide for increasing access to and use of human immunodeficiency virus (HIV)/sexually transmitted disease (STD) testing and sexual/reproductive healthcare (SRHC) among African American and Latino males.

A5288: MULTIOCTAVE, Management Using the Latest Technologies in Resource-limited Settings to Optimize Combination Therapy After Viral Failure

Post Date: 
2012-07-16
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This study was terminated in March 2020. It was a mult-country clinical trial conducted in Brazil, Haiti, India, Kenya, Malawi, Peru, South Africa, Thailand, Uganda, and Zambia under the AIDS Clinical Trials Group (ACTG) and funded by the U.S. National Institutes of Health. A5288 is a multi-step,...

Understanding Challenges and Perspectives of Parents about HIV Disclosures to their Children and Develop a Structured HIV Disclosure Model for Pediatric Age Group

Post Date: 
2011-12-08
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This study is terminated. In 2008 an estimated 70,000 children in India were living with HIV, with 21,000 new children are infected each year through mother to child transmission (Singh et al 2008). Increasing availability of antiretroviral treatment (ART) to HIV infected children in India means...

A5273: Multicenter Study of Options for Second-Line Effective Combination Therapy (SELECT)

Post Date: 
2011-05-12
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This study was terminated May 2, 2017; it was conducted under the AIDS Clinical Trials Group (ACTG) and funded by the U.S. National Institutes of Health. This was a multinational clinical trial conducted in Brazil, India, Kenya, Malawi, Peru, South Africa, Tanzania, Thailand, and Zimbabwe. The...

Predictors of Perinatal HBV Transmission in an HIV/HBV Infected Cohort

Post Date: 
2011-04-22
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This study ended in 2014. Hepatitis B virus (HBV) coinfection is common; affecting greater than 10% of HIV-infected individuals in resource-limited settings(1-3). Although the impact of HIV disease on HBV coinfection has been studied in non-pregnant adults, little is known about the effects of HIV...

A5282: A Randomized, Phase II Trial to Compare an HPV Test-and-Treat Strategy to a Cytology-Based Strategy for Prevention of CIN 2+ in HIV-Infected Women

Post Date: 
2011-03-15
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Indo-JHU partnership work on this trial was officially terminated September 10, 2018; it was conducted under the AIDS Clinical Trials Group (ACTG) and funded by the U.S. National Institutes of Health. This multi-country trial is being conducted in Botswana, Haiti, India, Malawi, Peru, South Africa...

A Prospective Study Evaluating the Role of Cryptococcal Antigen Screening among HIV-infected Adults with Low CD4 Counts

Post Date: 
2011-01-01
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This prospective observational study aimed to evaluate the burden of cryptococcal disease among approximately 200 HIV-infected adults with low CD4 cell counts in Pune, India to determine whether a Cryptococcal screening strategy should be the standard of care among patients with advanced HIV...

Brief Venue Survey of HIV Risk Places and Use of Technology in the Baltimore Latino Population

Post Date: 
2010-12-14
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This study ended December 13, 2011. In the last ten years, Baltimore City has seen a doubling in the AIDS incidence rate among Latinos. This has been paralleled by a doubling of the Baltimore Latino population over the last five years. At the Baltimore City Health Department (BCHD), Latino patients...

P1073: Study of Immune Reconstitution Inflammatory Syndrome (IRIS) for International Sites Initiating Highly Active Antiretroviral Therapy (HAART) in Infants and Children < 72 Months of Age

Post Date: 
2010-11-15
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This study was terminated April 23, 2015. This was a multi-national study conducted in India, South Africa, and Tanzania under the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Network and funded by the U.S. National Institutes of Health...

PreventionRx Study: Home-based Counseling and Testing in Uganda

Post Date: 
2010-10-21
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This study was terminated August 29, 2014. A ‘platform’ for evaluating combination HIV prevention & care-HIV counseling & testing is essential to optimize HIV services. In collaboration with the University of Washington and the Integrated Community Based Initiatives (ICOBI) NGO in Uganda,...

P1077BF: Breastfeeding Version of the PROMISE Study (Promoting Maternal and Infant Survival Everywhere)

Post Date: 
2010-02-02
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This trial was terminated November 6, 2019. This multi-country trial is being conducted in India, Malawi, South Africa, Tanzania, Uganda, Zambia, and Zimbabwe, conducted under the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Network and funded...

P1077FF: Formula Feeding Version of the PROMISE Study (Promoting Maternal and Infant Survival Everywhere)

Post Date: 
2010-02-02
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This trial was terminated November 6, 2019. This multi-country trial is being conducted in India, Malawi, South Africa, Tanzania, Uganda, Zambia, and Zimbabwe, under the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Network and funded by the U.S...

Assessment of Active Tuberculosis amongst Asymptomatic HIV-infected Patients in Kakinada, India

Post Date: 
2009-07-23
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This study was conducted in 2008. Tuberculosis (TB) is a major public health threat in India and is the leading cause of morbidity and mortality amongst people living with HIV/AIDS worldwide.1 According to the WHO, India accounts for one-fifth of the global TB incident cases, with over 1.9 million...

A5225: Phase I/II Dose-Finding Study of High-Dose Fluconazole Treatment in AIDS-Associated Cryptococcal Meningitis

Post Date: 
2009-04-22
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This trial was terminated in March 2015; it was conducted under the AIDS Clinical Trials Group (ACTG) and funded by the U.S. National Institutes of Health. This multi-country study was conducted in India, Kenyam Peru, South Africa, Thailand, Uganda, United States, and Zimbabwe. A5225/HiFLAC is a...

Impact of Malnutrition on HIV Treatment Failure in Resource-limited Settings

Post Date: 
2009-04-02
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This study, NWCS 319, was terminated August 20, 2019. Highly active antiretroviral therapy (HAART) has reduced morbidity and mortality among HIV-infected persons worldwide. However, early treatment failure (i.e. WHO stage 3 or 4 illnesses or death during the first 24 months of HAART) is more than 3...

A5253: Sensitivity and Specificity of Mycobacterium Tuberculosis Screening and Diagnostics in HIV-Infected Individuals

Post Date: 
2009-03-19
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This study was terminated October 15, 2014. An estimated 3 million HIV-infected individuals will enter programs for antiretroviral (ARV) treatment in the coming year, with projected rates of requirement for ARV therapy extending to more than 10 million in sub-Saharan Africa, southeastern Asia, and...

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