Publications - HIV

Peer Health Workers and AIDS Care in Rakai, Uganda: A mixed methods operations research evaluation of a cluster-randomized trial

Post Date: 
2011-12-15
   |   
Countries: 
Publication: 
AIDS Patient Care and STDs
Settings with limited health care workers are challenging environments for delivery of antiretroviral therapy. One strategy to address this human resource crisis is to task shift through training selected patients as peer health workers (PHWs) to provide care to other individuals receiving...

HIV transmitted drug resistance in adult and pediatric populations in Panama

Post Date: 
2011-12-15
   |   
Countries: 
Publication: 
Revista Panamerica de Salud Publica--Pan American Journal of Public Health
Objective: To investigate the prevalence of transmitted drug-resistant HIV among adults in Panama by using a modified World Health Organization Threshold Survey (WHO-TS) and to investigate rates of initial resistance among HIV-positive infants in Panama. Methods: At...

Nutrition and disease progression pre-highly active antiretroviral therapy (HAART) and post-HAART: Can good nutrition delay time to HAART and affect response to HAART

Post Date: 
2011-12-15
Publication: 
American Journal of Clinical Nutrition
Several studies have investigated a variety of nutritional supplementation interventions in adults with HIV. In this narrative review, we summarize the evidence from 31 clinical trials that explore clinical benefits of macronutrient and micronutrient supplementation in this population while...

Impact of maternal human immunodeficiency virus infection on pregnancy and birth outcomes in Pune, India

Post Date: 
2011-12-15
   |   
Countries: 
   |   
Clinical Sites: 
Publication: 
AIDS Care
Little is known about birth outcomes for HIV-infected women in India. We examine maternal and neonatal birth outcomes in HIV-infected women within the context of enhanced pre-natal care associated with a randomized clinical trial conducted in Pune, India. Birth outcomes of 212 HIV-infected...

Impact of a mHealth intervention for peer health workers on AIDS Care in rural Uganda: a mixed methods evaluation of a cluster-randomized trial

Post Date: 
2011-11-15
   |   
Countries: 
Publication: 
AIDS and Behavior
Mobile phone access in low and middle-income countries is rapidly expanding and offers an opportunity to leverage limited human resources for health. We conducted a mixed methods evaluation of a cluster-randomized trial exploratory substudy on the impact of a mHealth (mobile phone) support...

Symptom screening among HIV-infected pregnant women is acceptable and has high negative predictive value for active tuberculosis

Post Date: 
2011-11-15
   |   
Countries: 
   |   
Clinical Sites: 
Publication: 
Clinical Infectious Diseases
Symptom screening is a recommended component of intensified case-finding (ICF) for pulmonary tuberculosis (TB) among HIV-infected individuals. Symptomatic individuals are further investigated to either exclude or diagnose pulmonary TB, thus reducing the number of individuals requiring costly...

Increased gonorrhea and chlamydia testing did not increase case detection in an HIV clinical cohort 1999 - 2007

Post Date: 
2011-10-15
   |   
Countries: 
Publication: 
Sexually Transmitted Infections
Objectives: Since 2003, U.S. organizations have recommended universal screening, rather than targeted screening, of HIV-infected persons for gonorrhea (NG) and Chlamydia (CT). Our objective was to determine whether wider testing resulting from these guidelines would produce an increase in NG/CT...

Prevention of HIV-1 infection with early antiretroviral therapy

Publication: 
New England Journal of Medicine
Background: Antiretroviral therapy that reduces viral replication could limit the transmission of human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples. Methods: In nine countries, we enrolled 1763 couples in which one partner was HIV-1–positive and the other was HIV-1–negative; 54...

High rates of all-cause and gastroenteritis-related hospitalization morbidity and mortality among HIV-exposed Indian infants

Post Date: 
2011-07-15
   |   
Countries: 
   |   
Clinical Sites: 
Publication: 
BMC Infectious Diseases
Background: HIV-infected and HIV-exposed, uninfected infants experience a high burden of infectious morbidity and mortality. Hospitalization is an important metric for morbidity and is associated with high mortality, yet, little is known about rates and causes of hospitalization among these...

Cost-effectiveness of new WHO recommendations for prevention of mother-to-child transmission of HIV in a resource-limited setting

Post Date: 
2011-05-15
   |   
Countries: 
Publication: 
AIDS
Objective : Nigeria has high rates of mother-to-child HIV transmission. We sought to determine whether new WHO recommendations for long-course antiretroviral therapy (ART) prophylaxis are cost-effective for prevention of mother-to-child transmission (PMTCT) of HIV compared to short-course...

Mortality in HIV infected individuals in Pune, India

Post Date: 
2011-04-15
   |   
Countries: 
Publication: 
Indian Journal of Medical Research
Background & Objectives: With the presence of HIV epidemic for more than two decades in India, rise in the number of HIV related deaths is expected. Data on mortality in HIV infected individuals from prospective studies are scanty in India. We report here data on mortality in a...

Mixed methods evaluation of an international internet-based continuing medical education course for pediatric HIV providers in Pune, India

Post Date: 
2011-04-09
   |   
Countries: 
Publication: 
Education for Health
Context: Studies of HIV care in Pune, a high-HIV-prevalence city in India, have shown that a significant proportion of practitioners were not adhering to national guidelines due to inadequate awareness and understanding. Objectives: This study examined the...

Twelve month follow-up of the SWEN randomized controlled trials: Differential impact of extended-dose nevirapine on mother-to-child transmission and infant death by maternal CD4 cell count

Post Date: 
2011-03-27
   |      |   
Clinical Sites: 
Publication: 
AIDS Care
Objectives: We previously reported combined analysis of 6-week and 6-month endpoints of three randomized controlled trials [Six Week Extended Dose Nevirapine (SWEN) trials] that compared extended-dose nevirapine through 6 weeks of age to single-dose nevirapine to prevent HIV transmission via...

Predictors of retention among men attending STI clinics in HIV prevention programs and research: A case control study in Pune, India

Post Date: 
2011-03-11
   |   
Countries: 
   |   
Clinical Sites: 
Publication: 
PLOS One
Background: Retention is critical in HIV prevention programs and clinical research. We studied retention in the three modeled scenarios of primary prevention programs, cohort studies and clinical trials to identify predictors of retention. Methodology/Principal Findings: Men attending Sexually...

Maternal tuberculosis: a risk factor for mother-to-child transmission of human immunodeficiency virus

Post Date: 
2011-02-01
   |   
Countries: 
   |   
Clinical Sites: 
Publication: 
The Journal of Infectious Diseases
Background: Maternal human immunodeficiency virus (HIV) RNA load, CD4 cell count, breast-feeding, antiretroviral use, and malaria are well-established factors associated with mother-to-child transmission (MTCT) of HIV; the role of maternal tuberculosis (TB), however, has not been well...

Predictors of HIV testing among Latinos in Baltimore City

Post Date: 
2010-12-15
   |   
Countries: 
Publication: 
Journal of Immigrant and Minority Health
To better understand access to HIV testing and prevention services experienced by Latinos, we evaluated data compiled through Baltimore City Health Department HIV outreach efforts in 2008. Of 6,443 clients served, Latinos were more likely male, young, and less-educated than non-Latinos. A...

Gonorrhoea and chlamydia testing rates of HIV-infected men: low despute guidelines

Post Date: 
2010-11-15
   |   
Countries: 
Publication: 
Sexually Transmitted Infections
Objectives: Screening HIV-infected men for gonorrhea (GC) and Chlamydia (CT) may decrease HIV transmission and reduce the incidence of pelvic inflammatory disease in female partners. This study determined GC/CT testing rates in a clinical HIV cohort before and after 2003 when the U.S. Centers for...

Stigmatizing attitudes and low levels of knowledge but high willingness to participate in HIV management: A community based survey of pharmacies in Pune, India

Post Date: 
2010-08-27
   |   
Countries: 
Publication: 
BMC Public Health
Background: The World Health Organization (WHO) recommends that the role of pharmacists in low-income settings be expanded to address the increasing complexity of HIV antiretroviral (ARV) and co-infection drug regimens. However, in many such settings including in India, many pharmacists and...

Unique aspects of the care of HIV-positive Latino patients living in the United States

Post Date: 
2010-08-15
   |   
Countries: 
Publication: 
Current HIV/AIDS Reports
Latinos are disproportionately affected by HIV, with a higher risk of infection and a delayed presentation to care as compared to non-Hispanic whites. Over the last decade many Latinos, especially foreign-born migrants, have settled in regions of the country with historically low Latino...

Antiretroviral regimens for patients with HIV who fail first-line antiretroviral therapy

Post Date: 
2010-06-16
Publication: 
Cochrane Database of Systematic Reviews
Background: Highly active antiretroviral therapy has reduced the morbidity and mortality of patients with HIV/AIDS. A common first-line ART regimen in low-resource settings includes a non-nucleoside reverse transcriptase inhibitor (NNRTI) and two nucleoside reverse transcriptase inhibitors (...

Pages