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Declining HIV infection rates among recently married, pregnant women in Pune, India
Journal of Acquired Immune Deficiency Syndromes
Background: A single recent study has suggested a decrease in HIV risk for women attending antenatal clinics (ANCs) in southern India. Yet, some have questioned the validity of the Indian national surveillance data and analyses. Previous studies suggest that the only major HIV risk factor for married Indian women is the risk behavior of their husbands. Therefore, to address concerns about potential selection bias in the analysis of sentinel surveillance data from multiple sites, we estimated the trajectory of HIV transmission rates among recently married, monogamous, primigravid women attending a single large ANC in Pune, India.
Methods: Participants were self-referred, young, primigravid women from 18 to 27 years of age consenting to HIV screening. Time trends in HIV prevalence over 3.5 years were evaluated by logistic regression adjusted for age. HIV incidence was estimated by dividing the number of HIV-infected mothers by an estimate of exposure person-time, which was an estimate of the average age-specific duration of marriage.
Gupte N, Sastry J, Brookmeyer R, Phadke MA, Bhosale RA, Bollinger RC. Declining HIV infection rates among recently married, pregnant women in Pune, India. J Acquir Immune Defic Syndr. 2007 Aug 15; 570-573. Subscription Required.