Field evaluation of PIMA point-of-care CD4 testing in Rakai, Uganda

Post Date: 
2014-03-10
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Countries: 
Publication: 
PLOS One
Summary: 
Objective: To assess the accuracy of PIMA Point-of-Care (POC) CD4 testing in rural Rakai, Uganda.
 
Methods: 903 HIV positive persons attending field clinics provided a venous blood sample assessed on site using PIMA analyzers per manufacturer's specifications. The venous samples were then run on FACSCalibur flow cytometry at a central facility. The Bland-Altman method was used to estimate mean bias and 95% limits of agreement (LOA). Sensitivity, specificity, negative predictive value (NPV), and posibstract
Citation: 
Galiwango RM, Lubyayi L, Musoke R, Kalibbala S, Buwembo M, Jjingo K, Serwadda D, Gray RH, Reynolds SJ, Chang LW. Field evaluation of PIMA point-of-care CD4 testing in Rakai, Uganda. PLoS ONE. 2014;9(3): e88928. PMID: 24614083
Collaborators: 
  • Rakai Health Sciences Program, Kalisizo, Uganda
  • School of Public Health, Makerere University College of Health Sciences, Kampala, Uganda
  • Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
  • NID/NIAID, Bethesda, MD