Jeff Tornheim, MD, MPH

Baltimore, Maryland
Role: 
Faculty
Assistant Professor
Jeff Tornheim

Jeff Tornheim, MD, MPH, is Assistant Professor in the Division of Infectious Diseases here at Johns Hopkins University School of Medicine. His research explores the application of new diagnostic technologies to improved health outcomes in the treatment of drug resistant tuberculosis among both adult and pediatric patients in India. 

Dr. Tornheim recently completed his infectious diseases fellowship at Johns Hopkins, during which he worked with Drs. Amita Gupta, Vidya Mave, Bob Bollinger of Johns Hopkins, and with Dr. Zarir Udwadia at the Hinduja Hospital in Mumbai. His interest in clinical outcomes for underserved populations led him to practice in physician training environments in Bolivia, Peru, South Sudan, Kenya, Uganda, Rwanda, South Africa, and the United States.

Dr. Tornheim completed a clinical fellowship in infectious diseases in June 2017. Prior to that he completed residencies at Yale University in both internal medicine and pediatrics. He received an MD/MPH from Mount Sinai School of Medicine, with his thesis evaluating the impact of water policy on rates of pediatric diarrhea in Bolivia. After completing undergraduate studies in International Development and Economics at Brandeis University he moved to East Africa where he engaged in health system strengthening for returning refugees to South Sudan and worked with the Centers for Disease Control and Prevention (CDC) on the epidemiology of pneumonia and diarrhea in Western Kenya. At the same time he worked at the Bureau of TB Control for the Department of Health and Mental Hygiene and was actively engaged in the operations of an East Harlem free clinic. As a Fogarty International Clinical Scholar, he spent 2 years in rural Bolivia establishing and managing operations for a Chagas Disease treatment program.

MDR-TB Free: Monitoring Adverse Effects, Utilizing Resources Optimally, Knowing Resistance Patterns, and Treatment Strategy

Post Date: 
2017-03-24
Country: 
Purpose: To establish an observational cohort of MDR-TB cases and household contacts with accompanying biorepository at PD Hinduja National Hospital and Medical Research Centre Primary Objectives: Cohort A: To document participant outcomes including early treatment response, MDR-TB treatment-...

Multicenter Study of the Accuracy of the BD MAX MDR-TB Assay for Detection of M. tuberculosis Complex and Mutations Associated with Resistance to Rifampin or Isoniazid

Post Date: 
2017-03-01
Country: 
In a multi-country study, we are assessing the accuracy of the BD MAX rapid MDR-TB assay to detect rifampin and isoniazid resistance.

RePORT: C-TRIUMPH: Substudy on Transcriptomic and Metabolomic Analysis of Microbiologically Confirmed Pediatric Tuberculosis Patients and Uninfected Household Contacts

Post Date: 
2016-09-01
Country: 
The objectives for this study are to: Assess the RNAseq, microRNA, and metabolic signature differences between confirmed pediatric TB patients and age- and sex-matched controls who are all household contacts of known cases but have remained TST and IGRA negative. Determine which of the published...

Whole Genome Sequencing and Trek Sensititre Testing of Stored Isolates of Drug-resistant Tuberculosis from a Clinical Cohort at Hinduja Hospital, Mumbai

Post Date: 
2016-05-02
Country: 
Among HIV-positive TB patients presenting to Médecins San Frontières (MSF) clinics in Mumbai, 78% carried MDR-TB strains, with nearly half also found to have additional drug resistance. A previously published cohort of 202 patients cared for at these MSF clinics have enrolled in a cross-sectional...

Whole Genome Sequencing of Clinical Isolates from Patients with Multidrug Resistant Tuberculosis in India 

Post Date: 
2015-11-12
Country: 
Comparative genomic analysis using whole genome sequencing (WGS) offers an opportunity to understand the specific mutations associated with drug resistance and the phenotypic behavior of TB. As treatment programs incorporate more molecular diagnostics such as Xpert MTB/RIF and line probe assays, it...

Linezolid Experience among MDRTB Patients in Mumbai

Post Date: 
2017-09-13
Presentation Location: 
Milan, Italy
Country: 
Event & Convener: 
ERS International Congress. European Respiratory Society
Poster Presentation. Tornheim J, Ganatra S, Deluca A, Banka R, Rodrigues C, Gupta A, Udwadia Z .

Gene Expression Profiles of Pediatric Tuberculosis Patients and Exposed Controls from India

Post Date: 
2017-09-13
Presentation Location: 
Rio de Janiero, Brazil
Country: 
Event & Convener: 
RePORT International Conference. RICC
Poster Presentation. Tornheim JA , Paradkar M, Madugundu A, Gupte N, Kulkarni V, Sreenivasamurthy S, Raja R, Pradhan N, Shivakumar SVBY, Valvi C, Kohli R, Chandrasekaran P, Mave V, Pandey A, Gupta A.