Jonathan Golub, MPH, PhD

Role: 
Faculty
Associate Professor of Medicine, Epidemiology, and International Health
Jonathan Golub, MPH, PhD

Dr. Golub is an Associate Professor of Medicine, Epidemiology, and International Health at the Johns Hopkins School of Medicine and the Johns Hopkins Bloomberg School of Public Health. His research focuses on the epidemiology of tuberculosis in South Africa, Brazil, India and the US, with specific focus on the drivers of TB in these settings. He leads a cluster randomized trial in South Africa observing diagnostic and treatment practices for latent TB infection among HIV-infected patients at 14 HIV clinics. Also, in South Africa, he leads a smoking cessation clinical trial among HIV-infected patients and projects investigating indoor air pollution, smoking, and potential mHealth solutions for many patient populations. He also leads a study investigating TB treatment outcomes among TB patients with diabetes in India, and other studies in India looking at impact of indoor air pollution and smoking on TB in this setting.

In Brazil, he continues to lead a Fogarty training program which has trained more than 100 clinicians and public health researchers throughout Brazil. Recently, he helped lead the THRio study in Brazil, a cluster randomized trial in 29 HIV clinics throughout Rio de Janeiro, which showed that TB incidence can be reduced with proper implementation of TST and IPT. The data accumulated from THRio continue to fuel multiple analyses of the HIV/TB epidemic in Brazil, a country representative of middle income countries with a moderate TB epidemic.

In addition to the Fogarty training program, his interest in teaching extends to several TB courses at the Bloomberg School of Public Health. He is the primary instructor for the “Epidemiologic Basis for TB Control”, a course created by Dr. George Comstock over 50 years ago, and co-instructs two courses with Dr. Jaap Broekmans.

Impact of HIV and Diabetes Mellitus on TB Drug Resistance and Recurrence

Post Date: 
2017-03-02
Country: 
Tuberculosis (TB) is the leading cause of mortality globally. With increasing burden of HIV and diabetes mellitus (DM), there is a critical need to understand the microbial response and ensuing disease dynamics of TB in the HIV-infected and diabetic host to optimally control TB globally. Among...

Cost-effectiveness of Xpert MTB/RIF for Diagnosing Pulmonary Tuberculosis in HIV-positive Patients

Post Date: 
2016-12-01
Country: 
This is a prospective cross-sectional study which will be conducted at BJGMC in Pune, India. The aim of this study is to see whether Xpert MTB/RIF is useful for early detection of pulmonary tuberculosis, and therefore cost-effective, as compared with sputum microscopy and the gold standard tests...

RePORT: C-TRIUMPH: Substudy on Comparison of Available Purified-protein Derivative (PPD) Tuberculin Skin Test (TST) Antigen Solutions in Detecting Latent Tuberculosis Infection in India

Post Date: 
2016-04-21
Country: 
Given the worldwide shortage of PPD TST antigen solutions, it is important to establish the sensitivity of the commercially available SPAN diagnostic TST when compared products used in international settings. This study aims to establish whether the SPAN diagnostic product is bioequivalent to PPDs...

Barriers to Early Treatment Initiation in Childhood Tuberculosis in High Incidence Setting

Post Date: 
2016-04-21
Country: 
Funded by the Fogarty International Center and led by PI Dr. Chhaya Tukaram Valvi, the aim of this study is to evaluate the time to treatment initiation and barriers to early treatment initiation in childhood tuberculosis. TB diagnosis in children is challenging, often overlooked or missed, because...

Barriers to Implementation of Isoniazid Preventive Treatment (IPT) in Pediatric Contacts of Sputum Positive Adults with Tuberculosis

Post Date: 
2016-03-24
Country: 
Young children infected with M.tuberculosis can rapidly progress to pulmonary and extrapulmonary disease with high rates of mortality and morbidity. Studies worldwide have demonstrated that IPT not only prevents latent and asymptomatic TB from progression to clinical disease, it also effectively...

RePORT: C-TRIUMPH: Substudy on Assessing the Association of Indoor Air Pollution with Tuberculosis in Adult Women and Children under 5 Years of Age

Post Date: 
2013-09-15
Country: 
Addressing social and environmental risk factors contributing to TB disease is becoming increasingly important for national TB programs. We are leveraging the pediatric participants in 1,100 homes participating in the C-TRIUMPH study, enhancing data collection regarding household and individual...

Impact of Diabetes on TB Treatment Outcomes

Post Date: 
2013-02-01
Country: 
CCGHE, the JHU Center for TB Research and BJGMC have been awarded a $2.5 million dollar NIH grant (2013-2018) to conduct a study to evaluate treatment outcomes among Indian patients with both diabetes mellitus and active TB. This study is assessing the prevalence of impaired glucose or frank...

Post-arrival tuberculosis screening at a local health department of high-risk immigrants

Post Date: 
2015-07-15
Publication: 
American Journal of Public Health
Country: 
Objectives : We sought to characterize postimmigration tuberculosis (TB) care for Class B immigrants and refugees at the Baltimore City Health Department TB program (BCHD), and to determine the proportion of immigrants with active TB or latent TB infection (LTBI) in this high-risk population...

Analysis of latent tuberculosis infection treatment adherence among refugees and other patient groups referred to the Baltimore City Health Department TB clinic

Post Date: 
2015-02-15
Publication: 
Journal of Immigrant and Minority Health
Country: 
We sought to determine the proportion of refugee patients at the Baltimore City Health Department Tuberculosis program (BCHD-TB) successfully completing latent tuberculosis infection (LTBI) treatment, as compared to other referral groups, and to identify factors associated with treatment completion...

Trends in Glycated Hemoglobin Levels and Implications for Diabetes Screening among Pulmonary Tuberculosis Cases Undergoing Treatment in India

Post Date: 
2017-09-13
Presentation Location: 
Rio de Janiero, Brazil
Country: 
Event & Convener: 
3rd Annual RePORT International Meeting, RICC
Poster Presentation. Gupte AN , Mave V, Meshram S, Lokhande R, Kadam D, Dharmshale S, Bharadwaj R, Kagal A, Pradhan N, Deshmukh S, Atre S, Sahasrabudhe T, Barthwal M, Meshram S, Kakrani A, Kulkarni V, Raskar S, Suryavanshi S, Shivakoti R, Chon S, Selvin E, Gupte N, Gupta A, Golub JE

High Burden of Dysglycemia among Contacts of Tuberculosis Patients in India: Is it Time to Screen Them All?

Post Date: 
2017-09-13
Presentation Location: 
Rio De Janiero, Brazil
Country: 
Event & Convener: 
RePORT International Conference, RICC
Poster Presentation. Shivakumar SVBY , Chandrasekaran P, Paradkar M, Danasekaran K, Kumar AMV, Ramachandran G, Thomas B, Suryavarshini N, Kohli R, Thiruvengadam K, Gupte N, Kulkarni V, Hannah LE, Gomathy NS, Pradhan N, Dolla CK, Gupte A, DeLuca A, Meshram S, Kagal AD, Golub J, Selvaraj K, Murali L...

Validity of Reported Measures of Secondhand Smoke Exposure in Indian Households: Mishri Preparation a Potentially Overlooked Source in Low-Income Indian Communities

Post Date: 
2017-03-10
Presentation Location: 
Florence, Italy
Event & Convener: 
23rd Annual Meeting of the Society for Research on Nicotine & Tobacco (SRNT)
Oral presentation. Elf JL , Kinikar AA, Khadse S, Mave V, Gupte N, Kulkarni V, Patekar S, Raichur P, Cohen J, Breysse PN, Gupta A, Golub JE.

Factors Associated with Pulmonary Impairment in HIV-infected South African Adults

Post Date: 
2017-02-14
Presentation Location: 
Seattle, Washington
Country: 
Event & Convener: 
CROI 2017
Poster Presentation. Gupte A , Wong M, Msandiwa R, Barnes G, Golub J, Chaisson R, Hoffmann C, Martinson N

Host Factors Associated with Poor Respiratory Health-Related Quality of Life in Pulmonary Tuberculosis

Post Date: 
2017-02-03
Presentation Location: 
Hyderabad, India
Country: 
Event & Convener: 
6th Annual Regional Prospective Observational Research for Tuberculosis (RePORT) India Joint Leadership Meeting
Poster presentation. Gupte A , Meshram S, Selvaraju S, Gupte N, Shivakumar SVBY, Paradkar M, Kohli R, Theruvengadam K, Suryavanshi N, Chandrasekaran P, Mave V, Swaminathan S, Salvi S, Checkley, W, Golub J, Gupta A

Characteristics Associated with Mobile Phone Access among Tuberculosis Patents in Pune, India

Post Date: 
2016-12-04
Presentation Location: 
Cape Town, South Africa
Country: 
Event & Convener: 
46th Union World Conference on Lung Health. International Union for Tuberculosis and Lung Disease.
Poster Presentation. Ogale YP , Elf JL, Lokhande R, Mave V, Roy S, Gupta A, Golub J, Mathad J.

Host Factors Associated with Poor Respiratory Health-Related Quality of Life in Pulmonary Tuberculosis

Post Date: 
2016-10-27
Presentation Location: 
New Orleans, LA
Country: 
Event & Convener: 
ID Week 2016
Poster Abstract Session: Tuberculosis Treatment and Outcome. Gupte A , Meshram S, Selvaraju S, Gupte N, Shivakumar SVBY, Paradkar M, Kohli R, Theruvengadam K, Suryavanshi N, Chandrasekaran P, Mave V, Swaminathan S, Salvi S, Checkley, W, Golub J, Gupta A

Xpert® MTB/RIF Assay for Pulmonary Tuberculosis Diagnosis in Patients with Diabetes Mellitus

Post Date: 
2016-10-27
Presentation Location: 
Durban, South Africa
Event & Convener: 
47th Union World Conference on Lung Health. International Union for Tuberculosis and Lung Disease.
Poster Presentation. Mave V , Gupte N, Meshram S, Kagal A, Gupta A, Bharadwaj R, Pradhan N, Deshmukh S, Atre S, Golub J

The Association of Household Air Pollution and Tuberculosis in Women and Children in Pune, India

Post Date: 
2016-10-27
Presentation Location: 
Liverpool, England
Country: 
Event & Convener: 
46th Union World Conference on Lung Health. International Union for Tuberculosis and Lung Disease.
Elf JL , Kinikar A, Khadse S, Mave V, Gupte N, Kulkarni V, Patekar S, Raichur P, Breysse PN, Gupta A, Golub JE.

TB Infection Prevalence, Incidence and Risk Factors among Child and Adult Household Contacts of Adult TB Cases in India

Post Date: 
2016-10-27
Presentation Location: 
New Orleans, LA
Country: 
Event & Convener: 
ID Week 2016
Poster presentation. Shivakumar SVBY , Chandrasekaran P, Thiruvengadam K, Gupte N, Mave V, Hannah LE, Kulkarni V, Gupte A, Deluca A, Gomathy NS, Sathyamurthi P, Paradkar M, Kohli R, Meshram S, Kagal A, Suryavanshi N, Ramachandran G, Thomas B, Dolla CK, Subramanyam B, Golub J, Swaminathan S, Gupta A.

A Case-control Study of Household Air Pollution and Tuberculosis in Women and Children in Pune, India

Post Date: 
2016-10-26
Presentation Location: 
Liverpool, England
Country: 
Event & Convener: 
46th Union World Conference on Lung Health. International Union for Tuberculosis and Lung Disease
Oral Presentation. Elf JL , Kinikar A, Khadse S, Mave V, Gupte N, Kulkarni V, Patekar S, Raichur P, Breysse PN, Gupta A, Golub JE.

The Association of Household Air Pollution and Tuberculosis in Women and Children in Pune, India

Post Date: 
2016-09-22
Presentation Location: 
Durban, South Africa
Country: 
Event & Convener: 
RePORT International Meeting
Elf JL , Kinikar A, Khadse S, Mave V, Gupte N, Kulkarni V, Patekar S, Raichur P, Breysse PN, Gupta A, Golub JE. RePORT International Meeting. Durban, South Africa. 2016-07-14.

Prevalence of and Risk Factors for Diabetes mellitus among Pulmonary Tuberculosis Patients in Pune, India.

Post Date: 
2016-07-16
Presentation Location: 
Durban, South Africa
Country: 
Event & Convener: 
TB2016. International AIDS Society.
Poster presentation.

Characteristics Associated with Mobile Phone Access among TB Patients in Pune, India

Post Date: 
2015-12-04
Presentation Location: 
Cape Town, South Africa
Country: 
Event & Convener: 
The 46th Union World Conference on Lung Health
Poster Discussion. Session: What's App Doc? Use of m-Health. Authors: Ogale YP, Elf J, Lokhande R, Mave V, Roy S, Gupta A, Golub J, Mathad J.

The Association of Exposure to Air Pollution from Biomass Fuels, Kerosene, and Secondhand Tobacco Smoke with TB in Adult Women and Children in Pune, India

Post Date: 
2015-05-01
Presentation Location: 
Denver, CO
Country: 
Event & Convener: 
American Thoracic Society International Conference
Poster Session: Latent TB Infection: Diagnosis and Treatment. Oral Presentation. Elf JL , Kinikar A, Khadse S, Mave V, Gupte N, Kulkarni V, Patekar S, Raichur P, Breysse P, Gupta A, Golub J.

Yasmin Ogale

Yasmin Ogale received her MPH from Bloomberg School of Public Health in 2015. From September to December 2014, she conducted a field study in Pune, India, under the guidance of Dr. Jonathan Golub, on indoor air pollution and tuberculosis. Ms. Ogale is a 2014 recipent of the Global Health Established Field Placement Grant.

Akshay Gupte, MBBS, MSPH

Doctoral Student
Akshay Gupte, MBBS, MPH
Akshay Gupte, MBBS, MSPH, is a doctoral student in the Department of International Health at the Johns Hopkins Bloomberg School of Public Health (JHSPH). His research interests include exploring the impact of infectious diseases on lung health of populations and exploring approaches to host directed therapies to limit lung injury in TB. As part of his doctoral research, Akshay is leading a Indo-US collaborative study aimed at exploring the impact of TB disease—alone and in combination with HIV and diabetes mellitus—on pulmonary impairment and risk of chronic lung diseases in India. Akshay is...

Jessica Elf, MPH, PhD

Post Doctoral Fellow
Jessica Elf, MPH, PhD
Jessica Elf, MPH, PhD, is a post doctoral fellow in the Department of International Health at the Johns Hopkins School of Public Health. Her primary research focus has been on the epidemiology and health impacts of tobacco use and exposure to indoor air pollution from the combustion of biomass fuels. She is a former Fogarty Fellow who lived and worked in Pune, India conducting research for her thesis project, which investigated the association between indoor air pollution and tuberculosis. She completed her undergraduate education in nutrition at the University of Florida and received an MPH...

TB Noon Conference

Post Date: 
2013-10-24
Country: 
CCGHE webcasts Tuberculosis (TB) Noon Conference live and provides a global audience with open access to all live and archived sessions via the CCGHE website. Led by Drs. Maunank Shah, Jonathan Golub, Richard Chaisson, these meetings bring together Johns Hopkins TB researchers and trainees in an...