- Our Work
- Get Involved
In pregnant women on ART, safer to initiate isoniazid after delivery
Initiating 28-week isoniazid therapy during pregnancy was noninferior to initiating it 12 weeks after delivery to prevent tuberculosis in pregnant women with HIV who are on ART, according to results from a randomized controlled trial published in The New England Journal of Medicine. However, researchers found a greater risk for treatment-related adverse events in mothers who initiated treatment during pregnancy, suggesting that the best time to start isoniazid is after delivery.