RePORT India

Post Date: 
Clinical Sites: 

RePORT India is a joint venture between the Indian and US governments. The Indo-US Vaccine Action Program, a collaboration between the Indian Department of Biotechnology (DBT), the Indian Council of Medical Research (ICMR), and the US NIH, is co-funding six teams of India- and US-based investigators, to implement individual cohort studies of active and latent TB in India. Investigators are funded to enroll subjects into their own parent protocol. Eligible subjects from each parent protocol will be asked to co-enroll into the RePORT International Common Protocol. All subjects will be enrolled from the sites in India, and are expected to enroll active TB cases and latently TB infected (LTBI) households of active TB cases in their parent protocols. The sites are all experienced in TB clinical research, represent a mix of urban and rural, geographically disparate populations, and bring unique interests and expertise to their parent projects.

The specific sites comprising RePORT India are:

  1. The MV Diabetes Research Centre (MVDRC)  in Chennai, working with US partners at the University of Massachusetts to study the impact of diabetes on TB severity among adults
  2. Byramjee Jeejeebhoy Government Medical College (BJGMC) in Pune and the National Institute for Research in Tuberculosis (NIRT) in Chennai working with US partners at Johns Hopkins University to investigate host and microbial factors associated with active and latent TB infection in adults and children
  3. PD Hinduja Hospital and Medical Research Center in Mumbai, working with US partners at Johns Hopkins University to MDR-TB treatment outcomes, adverse effects, Mtb genotyping, and pharmacokinetic testing
  4. Bhagwan Mahavir Medical Research Centre in Hyderabad, working with the University of Texas Health Science Center to study the role of cellular immunity in preventing progression to active TB
  5. Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER) in Puducherry, working with Boston University Medical Center to study risk factors for treatment relapse and progression to active TB
  6. Christian Medical College (CMC) in Vellore, working with University of Washington to study the impact of adjunctive steroids for TB meningitis


An Executive Committee led by Drs. DJ Christopher and Amita Gupta provides leadership, governance, and guidance for the RePORT-India consortium. The consortium is also supported by a central bio-repository housed at the NIRT in Chennai, and a central data management center housed at the Society for Applied Studies-Centre for Health Research and Development in Delhi.

  • BJGMC, Pune, India
  • National Institute for Research in Tuberculosis (NIRT), Chennai, India
  • PD Hinduja Hospital, Mumbai, India
  • MV Diabetes Research Centre (MVDRC), Chennai, India
  • University of Massachusetts Medical School, Worcester, Massachusetts
  • Bhagwan Mahavir Medical Research Centre, Hyderabad, India
  • University of Texas Health Science Center, Tyler, TX
  • Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Puducherry, India
  • Boston University Medical Center, Boston, Massachusetts
  • Christian Medical College (CMC), Vellore, India
  • University of Washington/University of Cambridge