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Taking the long view on CREATE studies' finding
The Lancet Infectious Disease
In the past 10 years, the Consortium to Respond Effectively to the AIDS TB Epidemic (CREATE) has done three large trials exploring new strategies to control HIV-related tuberculosis. Recognising that the global strategy for tuberculosis control of a decade ago (mainly directly observed short-course therapy) was insufficient to combat tuberculosis epidemics fuelled by HIV, CREATE undertook bold, community-level trials using cluster randomised designs to assess new interventions that went beyond traditional approaches.
Chaisson RE, DeLuca A. Taking the long view on CREATE studies' findings. Lancet ID. 2014;14:366-367.