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TREAT Asia Observational Database
The TREAT Asia Observational Database's primary study objective is to:
- Examine HIV natural history, including the relationship between access to ART, demographics, and disease progression; short- and long-term responses to ART; impact of co-infections; HIV drug resistance patterns; and toxicity of first- and second-line regimens.
Secondary objectives include the following, and will be further identified as the study progresses:
- Facilitate the development of rigorous methods and standards of data collection across the region, enhancing the quality of local data and improving scientific capacity for operational research.
- Assess the risk of and factors associated with opportunistic infections (OI) and other AIDS-related illnesses (e.g., TB, Pneumocystis jiroveci pneumonia, HBV, HCV, HPV).
- Explore risk and outcomes of chronic diseases (e.g., hypertension, diabetes) and serious non-AIDS related endpoints (e.g., cardiovascular disease, liver and kidney failure).
- Examine social and clinical factors driving the epidemic (e.g., male-to-male sex, injection drug use).
- Study cancer risk, diagnostic testing capacity for oncogenic viruses, and types of cancers diagnosed in higher- and lower-resourced settings among HIV-infected persons.