India

With a population of more than one billion, India is the second largest country in the world, represents 16% of the global population, and the national average for life expectancy is only 65 years. India leads the world in the largest absolute burden of TB, ranks third for HIV (behind South Africa and Nigeria), and ranks second for diabetes. The country receives funding to support HIV/AIDS prevention, treatment and care programs under the US President's Emergency Plan for AIDS Relief (PEPFAR).

Our Indo-JHU Clinical Research Partnership is dedicated to reversing poor patient outcomes. With operations based in Pune, our extensive research portfolio is directed by Dr. Amita Gupta (Baltimore, MD), with onsite direction from Dr. Vidya MaveDr. Nishi Suryavanshi, and Dr. Nikhil Gupte (Pune). The Indo-JHU Partnership employs more than 200 people and, in addition to our memberships in consortia with many esteemed Indian research institutions, we have formal agreements with:

CCGHE WORK IN INDIA

Nutritional status and childhood growth among Korku and Warli tribes of Maharashtra: anthropometric perspective

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2013-01-01
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Explorations in Medical Anthropology
Nutritional status and childhood growth among Korku and Warli tribes of Maharashtra: anthropometric perspective.

Contracting in specialists for emergency obstetric care—does it work in rural India?

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2012-12-31
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BMC Health Services Research
Abstract Background: Contracting in private sector is promoted in developing countries facing human resources shortages as a challenge to reduce maternal mortality. This study explored provision, practice, performance, barriers to execution and views about contracting in...

Growth patterns among HIV-exposed infants receiving nevirapine prophylaxis in Pune, India

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2012-10-31
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BMC Infectious Diseases
Background: India has among the highest rates of infant malnutrition. Few studies investigating the growth patterns of HIV-exposed infants in India or the impact of timing of HIV infection on growth in settings such as India exist. Methods: We used data from...

Pooled individual data analysis of five randomized trials of infant nevirapine prophylaxis to prevent breast-milk HIV-1 transmission

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2012-10-19
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Clinical Infectious Diseases
Background: In resource-limited settings, mothers infected with human immunodeficiency virus type 1 (HIV-1) face a difficult choice: breastfeed their infants but risk transmitting HIV-1 or not breastfeed their infants and risk the infants dying of other infectious diseases or...

Vitamin D deficiency is common among HIV-infected breastfeeding mothers in Pune, India, but not associated with mother-to-child HIV transmission

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2012-10-01
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HIV Clinical Trials
A recent report from Tanzania demonstrated an increased risk of being HIV infected or of dying at birth among children born to breastfeeding mothers with low baseline vitamin D levels. We conducted a nested case-control study among HIV-infected pregnant women in western India to confirm the...

Evaluation of a multimodal, distance learning HIV management course for clinical care providers in India

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2012-10-01
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Journal of the International Association of Providers of AIDS Care
Distance learning is an important tool for training HIV health workers. However, there is limited evidence on design and evaluation of distance learning HIV curricula and tools. We therefore designed, implemented, and evaluated a distance learning course on HIV management for clinical care...

Detection of microbial translocation in HIV and SIV infection using the limulus amebocyte lysate assay is masked by serum and plasma

Post Date: 
2012-08-01
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PLOS One
Objective: Microbial translocation (MT) is thought to be a major contributor to the pathogenesis of HIV-related immune activation, and circulating lipopolysaccharide (LPS) from Gram-negative bacteria is the principle measurement of this process. However, related research has been impeded by...

Authors’ response to Hanrahan et al CID article

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2012-05-15
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Clinical Infectious Diseases
Reply to letter

Predictors of mortality in hospitalized children with pandemic H1N1 influenza 2009 in Pune, India

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2012-04-15
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Indian Journal of Pediatrics
Objective: To analyse the factors associated with increased mortality among Indian Children with H1N1. Methods: Data were abstracted from available hospital records of children less than 12 y of age, who were admitted to Sassoon General Hospital in Pune, India, with...

Determination of a reference interval in a population

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2012-02-01
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National Medical Journal of India
The reference interval is the most widely used medical decision-making tool that separates healthy from diseased individuals. We briefly discuss the methods used to determine reference interval and its limitations.

Global health education for medical students: New learning opportunities and strategies

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2012-01-17
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Medical Teacher
Background: A new course was offered to introduce basic global health concepts to all first year Johns Hopkins medical students, that took advantage of new distance learning capacity to connect medical students in Baltimore with students and faculty in Uganda, Ethiopia, Pakistan and India...

Sexually transmitted infections and risk behaviors among transgender persons (Hijras) of Pune, India

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2012-01-15
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Journal of Acquired Immune Deficiency Syndromes
Background: The objectives of this cross-sectional study were to determine the prevalence of HIV and sexually transmitted infections (STI) in Hijras (self-identified transgenders of South Asia), study associated risk factors, and compare the prevalence with that in heterosexual men and men...

Impact of maternal human immunodeficiency virus infection on pregnancy and birth outcomes in Pune, India

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2011-12-15
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AIDS Care
Little is known about birth outcomes for HIV-infected women in India. We examine maternal and neonatal birth outcomes in HIV-infected women within the context of enhanced pre-natal care associated with a randomized clinical trial conducted in Pune, India. Birth outcomes of 212 HIV-infected...

Symptom screening among HIV-infected pregnant women is acceptable and has high negative predictive value for active tuberculosis

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2011-11-15
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Clinical Infectious Diseases
Symptom screening is a recommended component of intensified case-finding (ICF) for pulmonary tuberculosis (TB) among HIV-infected individuals. Symptomatic individuals are further investigated to either exclude or diagnose pulmonary TB, thus reducing the number of individuals requiring costly...

Prevention of HIV-1 infection with early antiretroviral therapy

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New England Journal of Medicine
Background: Antiretroviral therapy that reduces viral replication could limit the transmission of human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples. Methods: In nine countries, we enrolled 1763 couples in which one partner was HIV-1–positive and the other was HIV-1–negative; 54...

High rates of all-cause and gastroenteritis-related hospitalization morbidity and mortality among HIV-exposed Indian infants

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2011-07-15
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BMC Infectious Diseases
Background: HIV-infected and HIV-exposed, uninfected infants experience a high burden of infectious morbidity and mortality. Hospitalization is an important metric for morbidity and is associated with high mortality, yet, little is known about rates and causes of hospitalization among these...

A comparison of online versus on-site training in health research methodology: A randomized study

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2011-06-17
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BMC Medical Education
Background: Distance learning may be useful for building health research capacity. However, evidence that it can improve knowledge and skills in health research, particularly in resource-poor settings, is limited. We compared the impact and acceptability of teaching two distinct content areas...

Early childhood growth among Mahadev Koli tribes of Maharashtra

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2011-06-01
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Voice of Intellectual Man
The present study aims “to study the growth status of the children of age group 0 to 5 years of Mahadev koli”. This cross-sectional study focuses on growth of children of age group 0 to 5 years in Ambegaon Taluka, Pune district, Maharashtra. Using De-facto population, 110 Mahadev Koli- 51 girls and...

Mortality in HIV infected individuals in Pune, India

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2011-04-15
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Indian Journal of Medical Research
Background & Objectives: With the presence of HIV epidemic for more than two decades in India, rise in the number of HIV related deaths is expected. Data on mortality in HIV infected individuals from prospective studies are scanty in India. We report here data on mortality in a...

Mixed methods evaluation of an international internet-based continuing medical education course for pediatric HIV providers in Pune, India

Post Date: 
2011-04-09
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Education for Health
Context: Studies of HIV care in Pune, a high-HIV-prevalence city in India, have shown that a significant proportion of practitioners were not adhering to national guidelines due to inadequate awareness and understanding. Objectives: This study examined the...

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