Archived Research Activities

Characterization of Findings on Upper Endoscopy

Post Date: 
2016-07-05
Country: 
BJMC is the primary facility for non-emergency endoscopies for a large portion of Pune's underserved population. Currently, there is limited data on the endoscopic findings in resource-limited settings, where the population receiving endoscopic evaluation may have clinically progressed findings...

Identifying Strategies to Optimize Prevention, Diagnosis, and Care of Tuberculosis in Health Care Workers of Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospital, Pune, India

Post Date: 
2015-10-01
Country: 
The BJGMC-JHU Fogarty program has identified tuberculosis in health care workers (HCW) as the program's most significant priority. Between June 2011 and December 2013, a total of 47 TB cases were identified among HCW's at the BJGMC Sassoon General Hospital. This study is being conducted by...

Predictive Val. of TB-symptom Screen in HIV-infected & -uninfected Pregnant Women in Pune, India. Substudy: Studying Molecular Mechanisms Leading to Suppressed Immunity in Pregnancy & Studying Relationship between Diet, Gut Microbiome, & Inflammation

Post Date: 
2014-10-28
Country: 
Pregnancy is a state of relative immunosuppression in order to protect the fetus from being rejected. It has also been shown that the Th-1 helper cell response, which is normally necessary for overcoming TB infection, is suppressed in pregnancy. Thus, pregnant women are especially vulnerable to TB...

ACTG 5279: Phase III Clinical Trial of Ultra-Short-Course Rifapentine/Isoniazid for the Prevention of Active Tuberculosis in HIV-Infected Individuals with Latent Tuberculosis Infection

Post Date: 
2014-06-30
Country: 
Dr. Amita Gupta is Protocol Co-Vice Chair for this multinational clinical trial being conducted in Botswana, Brazil, Haiti, Kenya, Malawi, Peru, Puerto Rico, South Africa, Tanzania, Thailand, Uganda, United States, Zambia, Zimbabwe, and India by the Baltimore-Washington-India Clinical Trials Unit,...

Ecobiosocial Approach for Dengue Vector Control

Post Date: 
2013-09-15
Country: 
Dengue is a major public health concern in the Region of the Americas. Working in a dengue endemic area of Colombia, the Centro de Estudios e Investigación en Salud (CEIS) Fundación Santa Fe de Bogotá conducting a multisite study focused on improved dengue prevention. CCGHE and Fundacion Santa Fe d...

Perceptions and Acceptability of mHealth Interventions: A Mixed Methods Study Using emocha®

Post Date: 
2013-09-14
Country: 
This comprehensive formative research study was designed to help guide the development and implementation of novel, task-shifting mHealth HIV/AIDS care interventions at a community-based HIV/AIDS clinic in Kampala, Uganda. Using emocha®, important knowledge was gained on acceptability and...

Hair Concentrations of Anti-tuberculosis Drugs Among HIV-infected and Uninfected Children in India

Post Date: 
2013-05-07
Country: 
In the developing world, tuberculosis (TB) is a major cause of mortality among HIV-infected children, a population where measuring treatment adherence and drug levels is difficult. We propose an innovative therapeutic drug monitoring (TDM) tool that measures drug concentration in hair samples to...

A5274: Reducing Early Mortality and Early Morbidity by Empiric Tuberculosis Treatment Regimens

Post Date: 
2011-10-01
Country: 
Dr. Amita Gupta is Protocol Co-Vice Chair for this multinational clinical trial being conducted in Brazil, Haiti, Kenya, Malawi, Peru, South Africa, Uganda, Zambia, and Zimbabwe , and in India by the Baltimore-Washington-India Clinical Trials Unit, of which CCGHE is a member. People with HIV have a...

Characterization of Pulmonary and Extrapulmonary Tuberculosis Among Adult Patients Admitted to Sassoon General Hospital, Pune, India

Post Date: 
2011-09-27
Country: 
The diagnosis of pulmonary and extrapulmonary tuberculosis is usually made clinically. While confirmation from laboratory tests is sought, the sensitivity of such diagnostic tests is poor. TB diagnostics are still evolving and in resource poor settings diagnostic availabilty is limited. Therefore,...

A Prospective Study Evaluating the Burden of Cryptococcal Disease Among HIV-infected Population in Pune, India

Post Date: 
2011-01-06
Country: 
By 2008, 33.4 million people were living with HIV globally, with an estimated 2.3 million living in India, representing the third largest absolute burden of HIV globally. [1] The current statistics as summarized by National AIDS Control Organization (NACO) of India show that of the estimated 750,...

EXposure Assessment in Current Time (EXACT) study

Post Date: 
2008-11-01
Country: 
Injection drug users (IDUs) are a marginalized population with substantial disparities in healthcare outcomes, especially among the HIV-infected IDU population. The EXACT study, which ended in 2013, was designed to optimize time to antiretroviral treatment (ART) initiation and retention-in-care...

Nursing Training Curriculum: HIV Practice and Reducing Stigma

Post Date: 
2004-01-01
Country: 
In 2004, CCGHE partnered with nursing leadership at Sassoon General Hospital, a 1500-bed public hospital in Pune, to develop a nursing training program to improve the care of patients with HIV. The program curriculum, developed by members of the Johns Hopkins (JH) AIDS Service (recognized worldwide...