Research News

Indian mother and child

Use of kerosene cooking fuel is positively associated with TB in women and children in our analysis using reported sources of exposure.

Group Photo, BJGMC Clinical Research Site, 2016, Pune, India

The Indo-JHU Clinical Research partnership at BJGMC in Pune, India, is now one of the top enrollers among all ACTG research sites internationally.

Clinical Research

Leadership
Dr. Amita Gupta of Johns Hopkins is Principal Investigator for the Indo-JHU Clinical Research Partnership based out of CCGHE. Research is directed locally in India out of the BJGMC-JHU Clinical Research Site by Dr. Vidya Mave, a Hopkins faculty member who lives in Pune. Dr. Nikhil Gupte is the Lead Biostatistician and Deputy Director and Dr. Nishi Suryavanshi is Clinical Site Coordinator and Deputy Director. Research is conducted in collaboration with the following institutions:
 
 

C-TRIUMPH: Immune Responses and Effect of Disulfiram on MTB Infected PBMCs as a Potential Host Directed Therapy

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2018-11-26
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Dr. Mandar Paradkar is lead investigator for this study that is assessing the immune responses of adult pulmonary TB patients enrolled in the CTRIUMPh study, using PBMC samples of those with harmful use of alcohol assessed by AUDIT scores ≥ 8 compared to non-alcoholics (AUDIT < 8). Aim 1: To...

C-TRIUMPH: Validating a Novel Functional Correlate of Immune Protection of Tuberculosis

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2018-10-03
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This is a longitudinal assessment of PBMC samples of progressors and non-progressors among adult household contacts of active TB patients. The purpose of the study is to probe the functional diversity of T cell responses to several of the antigens encoded by Mtb simultaneously in subjects covering...

Health Professions Education and Training for Strengthening the Health System and Services in Uganda

Post Date: 
2018-09-19
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Led by Sarah Kiguli at the Makerere University College of Health Sciences, the goal of this effort is to improve service delivery of the Ugandan health system through strengthened health professional interdisciplinary education and research training to produce graduates with competencies to address...

Assessing the Impact of Psychosocial Involvement in Health Care Workers with and without Active Tuberculosis at the Byramjee Jeejeebhoy Government Medical College, Pune, India

Post Date: 
2018-09-13
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This study is sposored by the Fogarty International Center at the U.S. National Institutes of Health. The overall goal is to understand the psychosocial involvement in health care workers with and without active tuberculosis. The specific aims of this study are: To understand the psychosocial...

TREAT Asia: Assessment of Depression and Anxiety among HIV-infected Adolescents in Pune, India

Post Date: 
2018-07-22
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PURPOSE The purpose of this study is to estimate the prevalence of depression and anxiety among adolescents living with HIV in India and their determinants. DESIGN Cross-sectional, single time point, conveniently sampled study conducted among adolescents (10-19 years) attending the ART clinic,...

Assessing Psychological Distress among Tuberculosis Patients and Their Household Members

Post Date: 
2018-07-17
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By assessing psychological distress, Indo-JHU researchers hope to better understand the correlation between depression and TB severity.

Evaluating the Source of Neonatal Bloodstream Infections due to Classically Hospital Acquired Pathogens in the Neonatal Intensive Care Unit in Pune, India

Post Date: 
2018-07-12
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This study is part of CDC's Safe healthcare, Epidemiology, and Prevention Research Development (SHEPheRD) Domain 7: International HAI and Other Adverse Healthcare Event Prevention. The PIs for this study are Dr. Julia Johnson of Johns Hopkins and Dr. Shilpa Naik of BJGMC. CoPIs are Dr. Aarti...

Assessing the Feasibility and Acceptability of a Computer-based Avatar-delivered Alcohol Reduction Intervention

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2018-07-05
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Study is assessing whether computer-delivered alcohol screening and intervention helps overcome barriers to treatment in India.

Molecular Signatures of Tuberculosis-Diabetes Interaction: Metabolomics Study

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2018-06-15
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Type 2 diabetes mellitus (DM) is an acquired host factor that increases the risk for and severity of pulmonary tuberculosis (PTB). A report published in 2007 estimated that, in India, DM accounted for 14.8% (range 7.1% to 23.8%) of PTB and 20.2% (8.3% to 41.9%) of smear-positive PTB. Emerging data...

Molecular Signatures of Tuberculosis-Diabetes Interaction: Transcriptomics Study

Post Date: 
2018-06-15
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Type 2 diabetes is an acquired host factor that increases the risk for and severity of pulmonary tuberculosis. A report published in 2007 estimated that, in India, diabetes accounted for 14.8% (range 7.1% to 23.8%) of pulmonary tuberculosis and 20.2% (8.3% to 41.9%) of smear-positive cases...

Gut Microbiota of HIV Infected Pregnant Women

Post Date: 
2018-06-14
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Birth Outcomes in HIV Both antiretroviral-therapy (ART)-naïve and ART-experienced HIV-infected pregnant women have higher incidences of pre-term birth (PTB) compared to HIV-uninfected women. For example, the global prevalence of PTB is around 8%, while the rates in in HIV-infected populations are...

Optimal Approach for TB Screening among HIV Infected Indian Children

Post Date: 
2018-06-11
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This study was funded by the Fogarty International Center at the U.S. National Institutes of Health. Determining TB status (ie, uninfected, latent, and active TB disease) is more difficult among children, particularly HIV-infected children. Diagnosis of TB disease is more difficult among HIV...

Evaluation of Video-Based Directly Observed Therapy for Tuberculosis in India

Post Date: 
2018-05-14
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This study was designed to evaluate Directly Observed Therapy conducted through miDOT, a secure mobile health interface, with traditional in-person Directly Observed Therapy.

Multidisciplinary Research Training to Understand and Reduce HIV Incidence in Uganda

Post Date: 
2018-05-10
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Dr. Larry Chang is PI for this multi-year (2018-2023) training grant sponsored by the Fogarty International Center at the National Institute of Health. Abstract While substantial progress has been made in the global HIV response, impact has been uneven. Uganda provides a prime case study. Uganda...

Implementing the Comprehensive Unit-based Safety Program to Reduce Healthcare-Associated Sepsis in the Neonatal Intensive Care Unit in Pune, India

Post Date: 
2018-04-19
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This study is part of CDC's Safe healthcare, Epidemiology, and Prevention Research Development (SHEPheRD) Domain 7: International HAI and Other Adverse Healthcare Event Prevention. Dr. Aaron Milstone is the PI, and Dr. Amita Gupta and Yuka Manabe are Co-PIs. the Study Investigator is Dr. Julia...

Predictors of Resistance Emergence Evaluation in Multidrug Resistant-Tuberculosis Patients on Treatment (PREEMPT Pilot Study)

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2018-03-20
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Indo-JHU Clinical Resarch Partnership is participating with Brazilian colleagues in a 3-year effort led by Boston University to identify what contributes to TB drug resistance.

A Multicenter Phase II/II Double-Blind, Randomized, Placebo Controlled Study to Evaluate the Efficacy and Safety of VPM1002 in the Prevention of Tuberculosis (TB) Recurrence in Pulmonary TB Patients After Successful TB Treatment in India

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2018-01-23
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Dr. Vidya Mave is leading this clinical trial evaluating the safety and efficacy of a new recombinant BCG vaccine.

Perceptions of HCWs on Barriers and Opportunities to Airborne Infection Control Guideline Implementation

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2017-12-07
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This study was funded by the Fogarty International Center at the U.S. National Institutes of Health. Led by Dr. Nishi Suryavanshi, this qualitative, cross-sectional study is assessing healthcare worker (HCW) perceptions about barriers and facilitators to the uptake of airborne infection control (...

A5302: BioBank for Surrogate Marker Research for TB (B-SMART)

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2017-11-21
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A5302 is a multi-center trial of the AIDS Clinical Trials Group (ACTG) in collaboration with the Tuberculosis Trials Consortium (TBTC).This study will be conducted at the BJ Government Medical College (BJGMC) in Pune, India. Study staff of the BJGMC will conduct the study and Johns Hopkins...

The Role of GeneXpert in Bacterial Diagnosis of Spinal Tuberculosis

Post Date: 
2017-10-26
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This study was funded by the Fogarty International Center at the U.S. National Institutes of Health. India has the maximum burden of tuberculosis (TB) in the world. In 2014, there were an estimated 9.6 million incident cases of TB (range, 9.1 million–10.0 million) globally, equivalent to 133 cases...

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The global landscape of tuberculosis therapeutics

Post Date: 
2018-11-07
Publication: 
Annual Review of Medicine
Abstract Tuberculosis (TB) is one of the oldest infections afflicting humans yet remains the number one infectious disease killer worldwide. Despite decades of experience treating this disease, TB regimens require months of multidrug therapy, even for latent infections. There have been important...

Drug-resistant Enterobacteriaceae colonization is associated with healthcare utilization and antimicrobial use among inpatients in Pune, India

Post Date: 
2018-10-04
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BMC Infectious Diseases
BACKGROUND: Healthcare exposure may increase drug-resistant Enterobacteriaceae colonization risk. Nascent antimicrobial stewardship efforts in low- and middle-income countries require setting-specific data. We aimed to evaluate risk factors for inpatient drug resistant Enterobacteriaceae...

Inflammation and micronutrient biomarkers predict clinical HIV treatment failure and incident active TB in HIV-infected adults: a case-control study

Post Date: 
2018-09-24
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BMC Medicine
Factors identified through exploratory factor analysis were associated with adverse outcomes in HIV-infected individuals.

Report of the Technical Consultation on Advances in Clinical Trial Design for Development of New TB Treatments

Post Date: 
2018-09-17
Publication: 
WHO Task Force on Introduction of New TB Drugs and Treatment Regimens
Dr. Amita Gupta was a member of this TB technical consultation, convened in March 2018 in Switzerland.

The association of household fine particulate matter and kerosene with tuberculosis in women and children in Pune, India

Post Date: 
2018-09-07
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Occupational and Environmental Medicine
Use of kerosene cooking fuel is positively associated with TB in women and children in our analysis using reported sources of exposure.

Challenges and opportunities for outreach workers in the Prevention of Mother to Child Transmission of HIV (PMTCT) program in India

Post Date: 
2018-09-04
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PLoS One
PLoS One: Prevention of Mother-to-Child Transmission of HIV program in India is one of the largest in the world, and it relies on outreach workers. Our study looked at challenges and opportunities for outreach workers.

Failure in TB control: why should the rapid diagnostic test bear the blame?

Post Date: 
2018-09-01
Publication: 
International Journal of Tuberculosis and Lung Disease
Dr. Sachit Atre's correspondence published in the International Journal of Tuberculosis and Lung Disease.

Resource utilization for multidrug-resistant tuberculosis household contact investigations (A5300/I2003)

Post Date: 
2018-09-01
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Publication: 
International Journal of Tuberculosis and Lung Disease
Current guidelines recommend evaluation of the household contacts of individuals with multidrug-resistant tuberculosis; however, implementation of this policy is challenging.

The effect of diabetes mellitus on the pharmacokinetics and pharmacodynamics of tuberculosis treatment

Post Date: 
2018-08-20
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Antimicrobial Agents and Chemotherapy
DM and higher HbA1c increased the risk of not achieving therapeutic targets for pyrazinamide, but higher pyrazinamide concentrations were asociated with worse microbiologic and clinical outcomes

Challenges of TB and co-treatment: updates and insights

Post Date: 
2018-08-04
Publication: 
Current Opinion in HIV and AIDS
PURPOSE OF REVIEW: In the past few years, tuberculosis (TB) has overtaken HIV as the infectious disease with the highest global mortality. Successful management of this syndemic will require improved diagnostic tests, shorter preventive therapies, and more effective treatments, particularly in...

Tuberculin skin test and QuantiFERON-Gold In Tube assay for diagnosis of latent TB infection among household contacts of pulmonary TB patients in high TB burden setting.

Post Date: 
2018-08-01
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PLoS One
World Health Organization (WHO) recommends systematic screening of high-risk populations, including household contacts (HHCs) of adult pulmonary tuberculosis (TB) patients, as a key strategy for elimination of TB. QuantiFERON-TB Gold In-Tube (QFT-GIT) assay and tuberculin skin test (TST) are two commonly used tools for the detection of latent tuberculosis infection (LTBI) but may yield differential results, affecting eligibility for TB preventive therapy.

Enhanced immigration enforcement in the USA and the transnational continuity of HIV care for Latin American immigrants in deportation proceedings

Post Date: 
2018-07-08
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Lancet HIV
Lancet HIV Opinion: Maintaining uninterrupted continuity of care among immigrants held in detention or deported to their home countries is challenging. In this Viewpoint, we identify periods of particular vulnerability for immigrants during deportation proceedings, from initial detention to deposition in their country of origin.

Trends in HbA1c levels and implications for diabetes screening in tuberculosis cases undergoing treatment in India

Post Date: 
2018-07-01
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Publication: 
International Journal of Tuberculosis and Lung Disease
SETTING: The optimal timing of screening for diabetes mellitus (DM) among tuberculosis (TB) cases is unclear due to the possibility of stress hyperglycemia. DESIGN: We evaluated adult (18 years) pulmonary TB cases at treatment initiation as well as at 3 months, 6 months and 12 months. DM was...

Internal medicine residents' knowledge and practice of pulmonary tuberculosis diagnosis

Post Date: 
2018-06-27
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Publication: 
Open Forum Infectious Diseases
BACKGROUND: Internal medicine physicians are often the first providers to encounter patients with a new diagnosis of tuberculosis. Given the public health risks of missed tuberculosis cases, assessing internal medicine residents' ability to diagnose tuberculosis is important. METHODS: Internal...

Loss to follow‐up and mortality among HIV‐infected adolescents receiving antiretroviral therapy in Pune, India

Post Date: 
2018-06-25
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HIV Medicine
Over 6 years, one-third of HIV+ adolescents in this study discontinued medical treatment, indicating a critical need for retention counselling and closer clinical monitoring.

Effect of baseline micronutrient and inflammation status on CD4 recovery post-cART initiation in the multinational PEARLS trial

Post Date: 
2018-05-29
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Clinical Nutrition
Nutritional deficiency and inflammation may impact CD4+ T cell recovery during combination antiretroviral therapy (cART), particularly in resource-limited settings where malnutrition is prevalent. The aim of this study was to investigate the relationship of micronutrient and inflammation biomarkers to CD4 recovery after cART initiation.

Sources of household air pollution and their association with fine particulate matter in low-income urban homes in India

Post Date: 
2018-05-23
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Publication: 
Journal of Exposure Science and Environmental Epidemiology
INTRODUCTION: Household air pollution (HAP) is poorly characterized in low-income urban Indian communities. MATERIALS AND METHODS: A questionnaire assessing sources of HAP and 24 h household concentrations of particulate matter less than 2.5 microns in diameter (PM 2.5 ) were collected in a sample...

The global neurological burden of tuberculosis

Post Date: 
2018-05-18
Publication: 
Seminars in Neurology
Central nervous system (CNS) involvement of tuberculosis (TB) is the most severe manifestation of TB and accounts for approximately 5 to 10% of all extrapulmonary TB (EPTB) cases and approximately 1% of all TB cases. TB meningitis (TBM) is the most common form of CNS TB, though other forms occur,...

Group mentorship model to enhance the efficiency and productivity of PhD research training in Sub-Saharan Africa

Post Date: 
2018-05-04
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Publication: 
Annals of Global Health
Annals of Global Health : Systems capacity building approach to PhD training allowed strong outputs at lower cost and with relatively few additional mentors to train independent scientists able to conduct original research and mentor others.

Addressing knowledge gaps and prevention for tuberculosis-infected Indian adults: a vital part of elimination

Post Date: 
2018-05-02
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BMC Infectious Diseases
BMC Infectious Diseases : Our survey among TB patients' household contacts with evidence of recent exposure found that knowledge is poor and families are confused about disease transmission.

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Mobile Phone Access and Comfort: Implications for HIV and Tuberculosis Care in India and South Africa

Post Date: 
2018-10-04
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Cox SN , Elf J, Lokhande R, Ogale YP, DiAndreth L, Dupuis E, Milovanovic M, Mpongose N, Martinson N, Mave V, Suryavanshi N, Gupta A, Golub JE, Mathad JS. Mobile Phone Access and Comfort: Implications for HIV and Tuberculosis Care in India and South Africa. I DSA. IDWeek 2018. San Francisco, CA,...

Perinatal Depression among HIV and TB Infected and Uninfected Women in an Urban Slum in India: Prevalence and Associated Birth Outcomes

Post Date: 
2018-10-04
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Grossman TB , Bhosale R, Alexander M, Suryavanshi N, Mave V, Jain D, Patil NU, Gupta A, Mathad JS. Perinatal depression among HIV and TB infected and uninfected women in an urban slum in India: prevalence and associated birth outcomes. IDSA. ID Week 2018. San Francisco, CA. October 3-7, 2018.

Antibiotic Use and Drug-Resistant Late-Onset Infections Among Neonates Admitted to Neonatal Intensive Care Units in Pune, India

Post Date: 
2018-08-28
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Agarkhedkar S, Armstrong D, Bharadwaj R, Cox SR, Dohe V, Gupta A, Gupte N, Johnson J, Kadam A, Kinikar A, Malwade S, Manabe Y, Mave V, Milstone A, Parikh T, Rajput U, Randive B, Robinson M , Smith R, Suryavanshi N, Vaidya U, Westercamp M. Antibiotic Use and Drug-Resistant Late-Onset Infections...

High Prevalence of Dengue among Pregnant Women in India

Post Date: 
2018-08-27
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Alexander M, Naik S, Robinson M , Sapkal G, Deshpande P, Kulkarni V, Nimkar S, Sambarey P, Kinikar A, Mave V, Suryavanshi N, Gupte N, Bollinger R, Gupta A, Bharadwaj R, Mathad J. High Prevalence of Dengue among Pregnant Women in India. 2018 International Conference on Emerging Infectious Diseases...

Association of Maternal Viral Load and CD4 Count with Perinatal HIV-1 Transmission Risk during Breastfeeding in the PROMISE Postpartum Component

Post Date: 
2018-07-26
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Flynn P, Taha T, Cababasay M, Butler K, Fowler MG, Mofenson L, Owor M, Fiscus S, Stranix-Chibanda L, Coutsoudis A, Gnanshanmugam D, Chakhtoura N, McCarthy K, Mukuzunga C, Makanani B, Moodley D, Nematadzira T, Kusakara B, Patil S, Vhembo T, Bobat R, Mmbaga B, Masenya M, Nyati M, Theron G, Mulenga H...

Mobile Health and Behavioral PMTCT Intervention among Community Health Workers Improves Exclusive Breastfeeding and Early Infant Diagnosis in India: A Cluster Randomized Trial

Post Date: 
2018-07-24
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Suryavanshi N, Kadam A, Hegde A, Sivalenka S, Kumar VS, McKenzie-White J, Kanade S, Gupta A, Bollinger RC, Shankar A, Gupte N, Mave V. Mobile Health and Behavioral PMTCT Intervention among Community Health Workers Improves Exclusive Breastfeeding and Early Infant Diagnosis in India: A Cluster...

Opportunities, Challenges and Implications of m-Health Oral Cancer Screening for HIV-positive Individuals in India

Post Date: 
2018-07-23
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Joshi S, Chandanwale A, Sangle S, Marbaniang I , Khaire S, Thakur R, Gupta A, Chigurupati R, Mave V. Opportunities, Challenges and Implications of m-Health Oral Cancer Screening for HIV-positive Individuals in India. AIDS 2018. Amsterdam, The Netherlands. July 23-27, 2018.

Health-related Quality of Life in the A5274 Trial of TB Therapy in Advanced HIV

Post Date: 
2018-07-22
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Clinical Sites: 
Lando R, Sun X, Miyahara S, Hosseinpour MC, Bisson GP, Kumwenda J, Gupta A, Nyirenda M, Katendey K, Torres TS, Suryavanshi N, Beulah F, Opollo V, Shah NS on behalf of the A5274 study team. Health-related Quality of Life in the A5274 Trial of TB Therapy in Advanced HIV. TB 2018, Amsterdam, The...

Role of Maternal Viral Load and CD4 Count on Perinatal HIV-1 Transmission during Breastfeeding in the PROMISE Postpartum Component

Post Date: 
2018-07-20
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Clinical Sites: 
Flynn P, Taha T, Cababasay M, Butler K, Fowler MG, Mofenson L, Owor M, Fiscus S, Stranix-Chibanda L, Coutsoudis A, Gnanshanmugam D, Chakhtoura N, McCarthy K, Mukuzunga C, Makanani B, Moodley D, Nematadzira T, Kusakara B, Patil S , Vhembo T, Bobat R, Mmbaga B, Masenya M, Nyati M, Theron G, Mulenga H...

Association between Dietary Intake and the Composition of the Vaginal Microbiota

Post Date: 
2018-06-20
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Shivakoti R , Tuddenham S, Caulfield LE, Robinson C, Rave J, Ghanem K, Brotman R. Association between dietary intake and the composition of the vaginal microbiota. Society for Epidemiologic Research 51st Annual Meeting. Baltimore, MD. June 19-22, 2018.

Association between Dietary Intake and the Composition of the Vaginal Microbiota

Post Date: 
2018-06-09
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Shivakoti R , Tuddenham S, Caulfield LE, Robinson C, Rave J, Ghanem K, Brotman R. Association between Dietary Intake and the Composition of the Vaginal Microbiota. Oral presentation at Nutrition 2018 Conference. American Society for Nutrition. Boston, MA. June 9, 2018.

Bloodstream Infections among Neonates Admitted to Neonatal Intensive Care Units in Pune, India

Post Date: 
2018-05-05
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Johnson J , Rajput U, Valvi C, Bharadwaj R, Parikh T, Agarkhedkar S, Robinson M, Randive B, Gupte N, Smith R, Westercamp M, Mave V, Manabe Y, Milstone A, for the CDC SHEPheRD India Study Team. Bloodstream Infections among Neonates Admitted to Neonatal Intensive Care Units in Pune, India. Pediatric...

Linezolid Experience Among MDR-TB Patients in Mumbai

Post Date: 
2018-03-16
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Tornheim J. Linezolid Experience Among MDR-TB Patients in Mumbai. 2018 Research Retreat, Johns Hopkins Department of Medicine. Baltimore, MD. 2018.

Similar Clinical Outcomes Between Formula and Breastfeeding Women In PROMISE

Post Date: 
2018-03-07
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Hoffman RM , Angelidou K, Brummel S, Saidi F, Dula DE, Mave V, Fairlie L, Theron G, Kamateeka M, Chipato T, Violari A, Chakhtoura N, Currier JS, Fowler MG, for the IMPAACT PROMISE 1077BF/FF Team. Similar Clinical Outcomes Between Formula and Breastfeeding Women In PROMISE. CROI 2018. Boston, MA...

Randomized Trial of Safety of Isoniazid Preventive Therapy During or After Pregnancy

Post Date: 
2018-03-07
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Clinical Sites: 
Gupta A, Montepiedra G, Aaron L, Theron G, McCarthy K, Onyango-Makumbi C, Chipate T, Masheto G, Shin K, Zimmer B, Sterling TR, Chakhtoura N, Jean-Philippe P, Weinberg A for the IMPAACT P1078/TB APPRISE Study Team. Randomized Trial of Safety of Isoniazid Preventive Therapy During or After Pregnancy...

GLP-1 and C-Peptide are Associated with Insulin Resistance among PLWH in India

Post Date: 
2018-03-07
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Marbaniang I, Sangle S, Kadam D, Kulkarni V, Shere D, Gupte N, Gupta A, Mave V. GLP-1 and C-Peptide are Associated with Insulin Resistance among PLWH in India. CROI 2018. Boston, MA. 2018

Inflammation in HIV-Infected Pregnant Women is Associated with Pre-term Birth

Post Date: 
2018-03-07
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Shivakoti R , Gupte N, Kumar NP, Kulkarni V, Balasubramanian U, Bhosale R, Sambarey P, Kinikar A, Bharadwaj R, Patil S, Inamdar S, Suryavanshi N, Babu S, Bollinger R, Gupta A. Inflammation in HIV-Infected Pregnant Women is Associated with Pre-term Birth. CROI 2018. Boston, MA. 2018

One Month of Rifapentine/Isoniazid to Prevent TB In People With HIV: Brief-TB/A5279

Post Date: 
2018-03-05
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Clinical Sites: 
Swindells S, Ramchandani R, Gupta A, Benson CA, Leon-Cruz JT, Omoz-Oarhe A, Juste MAJ, Lama JR, Valencia JA, Badal-Faesen S, Moran LE, Fletcher CV, Nuermberger E, Chaisson RE. One Month of Rifapentine/Isoniazid to Prevent TB In People With HIV: Brief-TB/A5279. CROI 2018. Boston, MA. 2018

Clinical Profile of Tuberculous Meningitis in a Tertiary Care Center in India. 5th Global Forum on TB Vaccines. New Delhi, India

Post Date: 
2018-02-21
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Clinical Sites: 
Basavaraj A. Clinical Profile of Tuberculous Meningitis in a Tertiary Care Center in India. Poster presented at 5th Global Forum on TB Vaccines. New Delhi, India. February 20-23, 2018.

Infection Free “Resistors” among Household Contacts of Culture-Confirmed Adult Pulmonary TB Cases

Post Date: 
2018-02-21
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Mave V , Chandrasekaran P, Paradkar M, Gupte A, Pradhan N, Kannan GN, Shivakumar SVBY, Kulkarni V, Dhanasekaran K, Subramanyam B, Selvaraju S, Murali L, Bharadwaj R, Gaikwad S, Meshram S, Kinikar A, Hanna LE, Swaminathan S, Gupte N, Gupta A. Infection Free “Resistors” among Household Contacts of...

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National Institutes of Health: Fogarty International Center Advisory Board

Post Date: 
2017-10-15
Advisory Board Member, 2017, Bollinger

ACTG Inflammation and End Organ Disease Transformative Science Group

Post Date: 
2016-01-01
Vidya Mave, Member, 2016–Present.

RePORT India Tuberculosis Consortium Common Protocol

Post Date: 
2016-01-01
Vidya Mave, Chair, 2016–Present

Johns Hopkins Hospital Microbiology Search Committee

Post Date: 
2014-01-01
Maunank Shah, Member, 2014.

CDC/PEPFAR HIV Implementation Research Study Group

Post Date: 
2012-01-01
Maunank Shah, Member, 2002.

CTG Co-Infection and Malignancy (COIMAL) Transformative Science Group

Post Date: 
2012-01-01
Vidya Mave, Member 2012–2014.

JHU Global mHealth Initiative

Post Date: 
2011-01-01
Bob Bollinger, Member. Johns Hopkins Bloomberg School of Public Health

Johns Hopkins Infectious Diseases Fellowship Recruitment and Selection Committee

Post Date: 
2009-01-01
Bob Bollinger, Member 2009–Present.

Consortium of Academic Centers Committed to Cross-Disciplinary Global Health Training and Mentorship

Post Date: 
2008-01-01
Bob Bollinger, Member, Consortium Working Group.

amFAR, The Foundation for AIDS Research, Scientific Advisory Committee

Post Date: 
2007-01-01
Larry Chang, Member, 2007.

IMPAACT Protocol Development and Monitoring Committee

Post Date: 
2007-01-01
Bob Bollinger, Member, 2007–2008.

Study Monitoring Committee, HPTN 046

Post Date: 
2007-01-01
Bob Bollinger, Member, 2007–2010. DAIDS, NIH HPTN Network Laboratory, HPTN 046, “HIV Prevention Trials Network Laboratory Phase III Trial to Determine the Efficacy and Safety of an Extended Regimen of Nevirapine in Infants Born to HIV Infected Women to Prevent Vertical HIV Transmission during...

Study Monitoring Committee, HPTN 057, Phase III Trial

Post Date: 
2007-01-01
Bob Bollinger, Member, 2007–2010. DAIDS, NIH HPTN Network Laboratory, HPTN 046, “HIV Prevention Trials Network Laboratory Phase III Trial to Determine the Efficacy and Safety of an Extended Regimen of Nevirapine in Infants Born to HIV Infected Women to Prevent Vertical HIV Transmission during...

Study Monitoring Committee, HPTN 057, Phase I Trial

Post Date: 
2007-01-01
Bob Bollinger, Member, 2007. HPTN 057, “HIV Prevention Trials Network Laboratory A Phase I Open Label Trial of the Safety and Pharmacokinetics of Tenofovir Disoproxil Fumarate in HIV-1 Infected Pregnant Women and their Infants”

Clinical Management Committee, HPTN 052

Post Date: 
2007-01-01
Bob Bollinger, Member, 2007–2010. HIV Prevention Trials Network Study HPTN 052, “A Randomized Trial to Evaluate the Effectiveness of ART plus HIV Primary Care versus HIV Primary Care Alone to Prevent the Sexual Transmission of HIV-1 in Serodiscordant Couples

Cross Network Immunology Quality Assurance Working Group

Post Date: 
2007-01-01
Bob Bollinger, Member, 2007–2008. HIV Prevention Trials Network Laboratory, DAIDS.

Johns Hopkins Medicine Point of Care Information Technology (POC-IT) Center

Post Date: 
2004-01-01
Bob Bollinger, Member, Advisory Board, 2004–2010.

American Society of Tropical Medicine and Hygiene

Post Date: 
1999-01-01
Bob Bollinger, Member, 1999–Present Amita Gupta, Member, 2001–2003

JHU Fogarty International Center, Program of International Training Grants in Epidemiology Related to AIDS

Post Date: 
1992-01-01
Bob Bollinger, Executive Committee Member. 1992–Present.

CCGHE at the Union 2018

Post Date: 
2018-09-26
Our Union dance card is full! Check out CCGHE's schedule of presentations at this year's conference.

Doctor who tackled HIV and other infectious diseases in India honored

Post Date: 
2018-09-11
Source: 
India Abroad
Robert Bollinger
India Abroad article highlights the dedication of the Raj and Kamla Gupta Professorship in Infectious Diseases.

National Institutes of Health Awards emocha Mobile Health $1 Million for Multi-State Study

Post Date: 
2018-08-29
emocha-logo
Bob Bollinger: "It is critical for patients to take tuberculosis medication as prescribed, and research supports new adherence strategies. . . "

Amita Gupta and Sujata Bhatia: Doing a World of Good

Post Date: 
2018-08-29
Source: 
American Institute of Chemical Engineers
Amita Gupta
Amita Gupta is interviewed by AIChE about the intersection of chemical engineering and medicine.

$17M is awarded to support HIV, disease ecology, mHealth projects

Post Date: 
2018-08-16
Source: 
Global Health Matters
NIH Fogarty International Center Logo
Larry Chang's Multidisciplinary Research Training to Understand and Reduce HIV Incidence in Uganda is among the funded projects.

BJGMC Clinical Research Team Exceeds 6,000 Participant Enrollments in 4 Years

Post Date: 
2018-08-03
Group Photo, BJGMC Clinical Research Site, 2016, Pune, India
The Indo-JHU Clinical Research partnership at BJGMC in Pune, India, is now one of the top enrollers among all ACTG research sites internationally.

Enhanced immigration enforcement in US could worsen HIV epidemic

Post Date: 
2018-07-21
Source: 
Infectious Disease News (via Healio)
Infectious Disease News-Healio
Kathleen Page: Immigrants living in fear of deportation often limit the use of services that they believe could expose them to authorities.

We Are Weill Cornell Medicine: Dr. Jyoti Mathad

Post Date: 
2018-05-18
Dr. Jyoti Mathad
Video by Weill Cornell Medicine features Jyoti Mathad and her work with the Indo-JHU Clinical Research Partnership.

Shah Receives Dr. David Glasser Memorial Award for TB Control in Maryland

Post Date: 
2018-04-27
Award recognizes significant contributions to TB prevention & control in MD.

Smartphone App Keeps an ‘Eye’ on Daily Tuberculosis Therapy

Post Date: 
2018-04-26
Johns Hopkins Medicine logo
Study shows success with TB therapy observation conducted via video instead of via in-person clinic visits.

World Tuberculosis (TB) Day Recognized with Community Event at BJGMC

Post Date: 
2018-04-17
World Health Day group activities at BJGMC Clinical Research Site in Pune, India
This year's themes: Maintaining healthy nutrition, addressing mental health challenges, and the latest in TB research.

Adverse pregnancy outcomes with isoniazid preventive therapy in HIV

Post Date: 
2018-03-09
Source: 
Infectious Disease Advisor
. . . The safety of IPT in pregnant women with HIV is unknown, especially with regard to its combination with highly active antiretroviral therapy (ART). Amita Gupta, MD, deputy director of the Johns Hopkins University Center for Clinical Global Health Education at the Johns Hopkins University...

No difference in safety for HIV+ pregnant women deferring TB Tx

Post Date: 
2018-03-09
Source: 
MedPage Today
MedPage Today
First randomized clinical trail of IPT in pregnant and postpartum women may suggest need for WHO guideline change.

Preventive TB therapy during pregnancy causes excessive adverse events

Post Date: 
2018-03-08
Source: 
Healio Infectious Disease News
. . . “Identifying ways to prevent TB during pregnancy and the postpartum period is a really important way to address maternal and infant health for a globally important disease such as tuberculosis,” Amita Gupta, MD, MHS, associate professor of medicine and international health and deputy director...

Study Results for IMPAACT P1078 Presented at CROI 2018

Post Date: 
2018-03-07
Source: 
IMPAACT Network News
IMPAACT Network News: Dr. Amita Gupta presented findings at CROI 2018.

CCGHE at CROI 2018

Post Date: 
2018-03-05
Check out where and when CCGHE presented at the Conference on Retroviruses and Opportunistic Infections. One Month of Rifapentine/Isoniazid to Prevent TB In People With HIV: Brief-TB/A5279 Swindells S, Ramchandani R, Gupta A, Benson CA, Leon-Cruz JT, Omoz-Oarhe A, Juste MAJ, Lama JR, Valencia JA,...

One-Month Tuberculosis Prophylaxis as Effective as Nine-Month Regimen for People Living with HIV

Post Date: 
2018-03-05
NIH Logo
The Indo-JHU Clinical Research Partnership participated in this important study that could change TB prevention for people living with HIV.

Tip Sheet: Johns Hopkins Researchers Present at Annual CROI Meeting

Post Date: 
2018-03-01
Newswise — Amita Gupta, M.D., deputy director of the Johns Hopkins University Center for Clinical Global Health Education at the Johns Hopkins University School of Medicine, will present a multicounty study of preventive treatment for tuberculosis (TB) in HIV-infected pregnant and postpartum women—...

2017 Year in Review

Post Date: 
2018-02-19
What a year! Our 2017 Year In Review outlines the most ambitious 365 days we’ve had to date.

WHO sets disease priorities for 2018; Tuberculosis once again not included

Post Date: 
2018-02-15
Source: 
Contagion Live: Infectious Diseases Today
CCGHE Director Bob Bollinger weighs in on WHO's priority pathogens for 2018.

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