Research News

Dr. Maunank Shah
September 24, 2021

A new Johns Hopkins Medicine mathematical model to predict how the human immunodeficiency virus (HIV) spreads in urban areas...

Clinical Research

Leadership
While we conduct research all over the world, the majority of our work is in India. Our Indo-JHU Clinical Research Partnership is located in Pune and is directed by Dr. Amita Gupta (Baltimore, MD), with onsite direction from Dr. Vidya Mave, Dr. Nishi Suryavanshi, and Dr. Nikhil Gupte (Pune). The Indo-JHU Partnership employs more than 200 people and in addition to our memberships in cosortia with many esteemed Indian research institutions, we have formal agreements with:

 
 

Creating a Hope: A Mixed-Method Approach to Identify Most Acceptable Evidence-Based Psycho-Social Intervention to Improve the Retention in Care among Indian Youth Diagnosed with Multi-Drug Resistant TB (MDR-TB)

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2021-11-02
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PURPOSE: Adolescents and youths with MDR/RR tuberculosis reported social isolation, stigmatization, depression, and poor self-esteem highlighting the importance of psychosocial support during tuberculosis treatment phase. Addressing the psycho-social need of youths, by identifying youth friendly...

Epidemiologic Factors Associated with TB Treatment Outcomes Across Report International Consortia

Post Date: 
2021-08-12
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Rationale: RePORT International was designed to enable cross-consortium data analysis. Now that a large number of consortium sites have completed participant enrollment in Common Protocol Cohort A, we can proceed with large-scale analysis of aligned RePORT data. The current study will harmonize and...

ACTIV-2/A5401: Adaptive Platform Treatment for Outpatients with COVID-19 (Adapt Out COVID)

Post Date: 
2021-07-21
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Rationale: There is an urgent need for a platform to rapidly evaluate therapies in the outpatient setting, to prevent disease progression, and reduce serious complications of COVID-19 and transmission [10]. ACTIV-2/A5401 is a phase II/III randomized, blinded, controlled adaptive platform trial to...

Project COVID-19 Test At Home

Post Date: 
2021-06-28
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This study to test the accuracy of a COVID-19 test for use at home. This test has been authorized by the FDA to be done in a health care setting by a health care provider, but the study is evaluating diagnostic accuracy of tests administered at home

P2026: Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs during Pregnancy and Postpartum

Post Date: 
2021-05-18
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IMPAACT P1026s, the predecessor of this study, was first approved in 2003. P1026s enrolled over 1000 pregnant/postpartum women, studied the PK of more than 25 HIV and TB drugs in these women and published 27 manuscripts presenting these data. P1026s data was cited in 32% of the 76 perinatal...

The Pharmacokinetics, Safety and Acceptability of New Child-Friendly Formulations of Clofazimine and Moxifloxacin in Children Routinely Treated for Rifampicin-Resistant Tuberculosis (CATALYST)

Post Date: 
2021-04-26
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PK, safety and acceptability data and practical guidance on the optimal dosing of new more child-friendly formulations of moxifloxacin and clofazimine in children are urgently needed to inform their current and future use in children with Rifampicin-Resistant TB (RR-TB). Both medications have a key...

Dynamics and immune mechanisms of QFT response in close contacts of TB cases

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2021-04-05
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Rationale: A vaccine that prevents infection with Mycobacterium tuberculosis (Mtb) (POI vaccine) is an ideal approach to TB control. As Mtb infection (MTBI) is measured indirectly (positive tuberculin skin test (TST) or interferon gamma release assay (IGRA), prevention of IGRA conversion is the...

A Nanopore Biosensor for Leveling MTB Antigens in Blood

Post Date: 
2021-04-01
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Purpose of the study: The inability to obtain diagnostically useful sputum specimens, or the inability to analyze non-sputum specimens, is a significant contributor to poor diagnostic sensitivity of current TB assays, leading to the WHO to call for the development of non-sputum-based biomarker or...

Effect of Neighborhoods and Peer Networks on substance use and violence among adolescents living with and without HIV in India

Post Date: 
2021-01-28
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Purpose of the study: A strong bidirectional association exists between substance use, various forms of violence and HIV. Substance use accounts for 0.8% of the burden of disease measured in disability adjusted life years (DALYs) among adolescents in South Asia. Violence among adolescents living...

COVID-19 Viral Dynamics

Post Date: 
2020-12-20
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Purpose of the study: This study aims to quantitatively define the relationships between (a) testing results obtained via multiple distinct platforms (antigen vs. RT-qPCR), (b) shedding of infectious virus, and (c) self-reported disease symptoms over the course of SARS-CoV-2 infection.

Impact of Tuberculosis Infection on HIV-1 Antibody Response (NWCS501)

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2020-12-05
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Study Objective: Compare longitudinal HIV-1 antibody responses among HIV-1 infected participants that either did or did not develop active TB enrolled in ACTG 5274 and ACTG 5279 Study Design: Longitudinal antibody responses will be examined among select participants in A5274 who have plasma samples...

Pharmacokinetic Assessment of MDR-TB Drugs in the Treatment of TB Meningitis

Post Date: 
2020-08-23
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Rationale: MDR-TBM is a devastating disease with high mortality and severe neurologic sequelae among survivors. We recognize the importance of sufficient drug concentrations at the site of infection for efficacy of anti-TB drugs and believe it is likely that drug distribution into brain and CSF...

Identification of Biomarkers That Can Predict Progression from Latent Tuberculosis Infection to Active Tuberculosis Disease

Post Date: 
2020-08-23
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Purpose: The C-TRIUMPH study has identified 20 household contacts (HHC), who have progressed to active TB from its HHCs cohort (Cohort B). Immunological profiling of TB antigen induced biosignatures, profiling of transcriptional and proteomic biosignatures should provide novel insights into the...

RADx Tech COVID-19 Test US Study

Post Date: 
2020-08-05
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Rationale: Scalable, inexpensive point-of-care (PoC) technologies that enable detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus are desperately needed. However, understanding the accuracy and usability of novel PoC technologies for SARS-CoV-2 is critical. Each PoC...

RADx Tech COVID-19 Test Us Bank

Post Date: 
2020-08-05
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This study is collecting and storing lab samples of COVID-19 diagnostic tests among both people who have tested positive for COVID and those who haven’t to evaluate new COVID test and study how COVID-19 and related viruses cause disease in people.

RADx Tech COVID-19 Test Us Study

Post Date: 
2020-07-27
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Scalable, inexpensive novel technologies that enable detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus are desperately needed. However, understanding the accuracy and usability of novel technologies for SARS-CoV-2 is critical. Each novel test needs to be evaluated...

Tuberculosis (TB) Aftermath

Post Date: 
2020-06-05
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Drs. Vidya Mave and Jonathan Golub are co-PIs and Dr. Barthwal from DY Patil Medical College is local site PI for this study. TB Aftermath seeks to provide evidence for an effective and scalable strategy targeting HHs of treated TB cases, a high priority of the NTEP. Purpose To compare the...

Mental Health Outcomes among Health Care Professionals Involved in the Treatment and Care of COVID 19 Patients in India

Post Date: 
2020-06-01
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Drs. Nikhil Gupta and Nishi Suryavanshi are leading this survey project. This study is investigating the immediate impact of the COVID-19 pandemic on mental health outcomes and overall quality of life and what are the factors associated with it among Indian Health care workers. Among health care...

Leveraging mHealth and peers to Engage African- Americans and Latinxs in HIV care (LEAN)

Post Date: 
2020-05-12
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Baltimore’s HIV prevalence rate (586/100,000) is among the top 5 in metropolitan areas in the US, and disparities are profound. African Americans have an HIV prevalence that is 5 times higher than among whites, and they account for 78% of all HIV cases. Latinxs also have a higher prevalence of HIV...

Prevalence of Risk Factors for Lung Cancer and Facilitators and Barriers for Tobacco Cessation among People Living with HIV

Post Date: 
2020-04-01
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India has the world’s third largest HIV epidemic, with 2.1 million people currently living with HIV and an additional 90,000 new infections each year.[29] At the same time, expansion of the HIV response under India’s premier governmental agency - the National AIDS Control Organization (NACO), has...

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Baseline IL-6 is a biomarker for unfavorable tuberculosis treatment outcomes: a multi-site discovery and validation study

Post Date: 
2021-11-08
Publication: 
The European Respiratory Journal
Dr. Akshay Gupte and colleagues discovered that elevated IL-6 can predict poor treatment outcomes, showcasing a need for including IL-6 in clinical screenings.

Validation of New Interactive Nutrition Assistant - Diet in India Study of Health (NINA-DISH) FFQ with multiple 24-h dietary recalls among pregnant women in Pune, India

Post Date: 
2021-11-02
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Publication: 
The British Journal of Nutrition
Adequate dietary intake is critical to prevent adverse pregnancy outcomes. India has a high burden of maternal and child morbidity and mortality, but there is a lack of adequate tools to assess dietary intake. We validate an FFQ, New Interactive Nutrition Assistant - Diet in India Study of Health (NINA-DISH), among pregnant women living with and without HIV in Pune, India.

Tuberculosis Pathways to Care and Transmission of Multidrug-Resistance in India

Post Date: 
2021-11-01
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Publication: 
American Journal of Respiratory and Critical Care Medicine
Rationale: India is experiencing a regional increase in cases of multidrug-resistant tuberculosis (MDR-TB). Given the complexity of MDR-TB diagnosis and care, we sought to address key knowledge gaps in MDR risk factors, care delays, and drivers of delay to help guide disease control. Methods: From...

What Will It Take to End HIV in the United States? : A Comprehensive, Local-Level Modeling Study

Post Date: 
2021-09-24
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Publication: 
Annals of Internal Medicine
Background: The Ending the HIV Epidemic (EHE) initiative aims to reduce incident HIV infections by 90% over a span of 10 years. The intensity of interventions needed to achieve this for local epidemics is unclear. Objective: To estimate the effect of HIV interventions at the city level. Design: A...

Health Systems and Tuberculosis Control

Post Date: 
2021-09-20
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Publication: 
Essential Tuberculosis
This chapter discusses the relationship between health systems and organization of tuberculosis (TB) control, which is generally a part and parcel of a health system. It juxtaposes the six building blocks of a health system identified by the World Health Organization (WHO) on WHO’s End TB Strategy...

Sex and gender differences in COVID testing, hospital admission, presentation, and drivers of severe outcomes in the DC/Maryland region

Post Date: 
2021-08-31
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Publication: 
medRxiv
Rates of severe illness and mortality from SARS-CoV-2 are greater for males, but the mechanisms for this difference are unclear.

Comparison of Time to Clinical Improvement With vs Without Remdesivir Treatment in Hospitalized Patients With COVID-19

Post Date: 
2021-03-24
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Publication: 
JAMA Network Open
Just Published in JAMA Network Open: In this retrospective analysis, remdesivir was associated with faster clinical improvement of COVID-19 in a cohort of predominantly non-White patients

Unhealthy alcohol use independently associated with unfavorable TB treatment outcomes among Indian men

Post Date: 
2021-03-10
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Publication: 
International Journal of Tuberculosis and Lung Disease
This study by Samyra Cox and colleagues highlights the need for integrating effective alcohol interventions into TB care.

Development of Severe COVID-19 Adaptive Risk Predictor (SCARP), a Calculator to Predict Severe Disease or Death in Hospitalized Patients With COVID-19

Post Date: 
2021-03-02
Publication: 
Annals of Internal Medicine
Dr. Matt Robinson and colleagues developed a real-time tool that can predict severe disease or death among COVID patients

Systemic Inflammation in Pregnant Women With Latent Tuberculosis Infection

Post Date: 
2021-01-27
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Publication: 
Frontiers in Immunology
Background: Recent studies in adults have characterized differences in systemic inflammation between adults with and without latent tuberculosis infection (LTBI+ vs. LTBI-). Potential differences in systemic inflammation by LTBI status has not been assess in pregnant women. Methods: We conducted a...

Higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis

Post Date: 
2021-01-18
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Publication: 
ERJ Open Resource
Higher levels of IL-6 and slow-to-resolve TGF-β are associated with lung impairment in treated tuberculosis. These results have important implications for clinical trials of immunomodulatory therapies to prevent tuberculosis-associated lung disease. http://openres.ersjournals.com/lookup/doi/...

Detection of genital tuberculosis among women with infertility using best clinical practices in India: An implementation study

Post Date: 
2021-01-15
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Publication: 
Indian Journal of Tuberculosis
Background Diagnosis of genital tuberculosis (TB) as a cause of infertility still remains a diagnostic dilemma for clinicians, as no standard guidelines exist. The recently proposed best practices for genital TB diagnosis have not been evaluated yet in India. Objectives To implement best practices...

Higher IL-6 Levels and Changes in TGF-β are Associated with Lung Impairment in Pulmonary Tuberculosis

Post Date: 
2021-01-08
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Publication: 
ERJ
Pulmonary tuberculosis (PTB) is associated with granuloma formation, necrosis and cavitation in lung tissue. Lung injury in PTB can persist despite microbiological cure and is associated with chronic obstructive pulmonary disease (COPD) independent of smoking exposure[1]. Furthermore, pulmonary...

Novel community health worker strategy for HIV service engagement in a hyperendemic community in Rakai, Uganda: A pragmatic, cluster-randomized trial

Post Date: 
2021-01-06
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Publication: 
PLOS Medicine
Effective implementation strategies are needed to increase engagement in HIV services in hyperendemic settings. We conducted a pragmatic cluster-randomized trial...

Validation of NINA-DISH food frequency questionnaire with multiple 24-hour dietary recalls among pregnant women in Pune, India

Post Date: 
2021-01-06
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Countries: 
Publication: 
The British Journal of Nutrition
Adequate dietary intake is critical to prevent adverse pregnancy outcomes. India has a high burden of maternal and child morbidity and mortality, but there is a lack of adequate tools to assess dietary intake. We validate a food frequency questionnaire (FFQ), New-Interactive Nutrition Assistant-...

Measuring TB drug levels in the hair in adults and children to monitor drug exposure and outcomes

Post Date: 
2021-01-01
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Publication: 
International Journal of Tuberculosis and Lung Disease
INTRODUCTION: Testing for anti-TB drugs in small hair samples may serve as a non-invasive tool to measure cumulative drug exposure and/or adherence, as these determine treatment success. We aimed to assess how well hair assays of TB drugs predict TB treatment outcomes.METHODS: A small thatch of...

Tocilizumab for the Treatment of COVID-19 Among Hospitalized Patients: A Matched Retrospective Cohort Analysis

Post Date: 
2020-12-28
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Publication: 
Open Forum Infectious Diseases
Background: There is currently no single treatment that mitigates all harms caused by severe acute respiratory syndrome coronavirus 2 infection. Tocilizumab, an interleukin-6 antagonist, may have a role as an adjunctive immune-modulating therapy. Methods: This was an observational retrospective...

Association of Vegetable and Animal Flesh Intake with Inflammation in Pregnant Women from India

Post Date: 
2020-12-08
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Publication: 
MDPI
In pregnant women, studies are lacking on the relationship of vegetable and animal flesh (poultry, red meat and seafood) intake with inflammation...

Nevirapine pharmacokinetics in HIV-infected persons receiving rifapentine and isoniazid for TB prevention

Post Date: 
2020-11-26
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Publication: 
The Journal of Antimicrobial Chemotherapy
Background: The use of rifamycin antibiotics for TB prevention carries a risk of detrimental drug-drug interactions with concomitantly used ART. Objectives: To evaluate the interaction of the antiretroviral drug nevirapine in combination with 4 weeks of daily rifapentine and isoniazid for TB...

Xpert MTB/RIF Ultra for the Diagnosis of Tuberculous Meningitis: A Small Step Forward

Post Date: 
2020-11-05
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Publication: 
Clinical Infectious Diseases
The delayed diagnosis of tuberculous meningitis (TBM) leads to poor outcomes, yet the current diagnostic methods for identifying Mycobacterium tuberculosis in cerebrospinal fluid (CSF) are inadequate. The first comparative study of the new GeneXpert MTB/RIF Ultra (Xpert Ultra) for TBM diagnosis...

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COVID-19 Lessons Learned

Post Date: 
2021-04-28
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Bollinger R. Speaker. COVIS-19 Lessons Learned. 47th Annual Annual Conference of Research Society, BJGMC and Sassoon General Hospital. Virtual confernece, based in Pune, India. Apri 28-29, 2021.

Reservoirs of transmission of resistant Gram-negative pathogens responsible for neonatal sepsis among hospitalized neonates in Pune, India

Post Date: 
2020-10-21
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Johnson J, Robinson ML, Naik S, Patil S, Kulkarni R, Kinikar A, Dohe V, Mudshinkar S, Kagal A, Smith RM, Westercamp M, Randive B, Kadam A, Kulkarni V, Mave V, Gupta A, Milstone AM, Manabe YC, for the CDC SHEPheRD India Study Team. Reservoirs of transmission of resistant Gram-negative pathogens...

Screening for Tuberculosis (TB) in pregnant and non-pregnant women of reproductive age: Findings from an observational study in Pune, India

Post Date: 
2020-10-20
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Alexander M, Bhosale R, Naik S, Kulkarni V, Mave V, Suryavanshi N, Gupte N, Gupta A, Mathad J. Screening for Tuberculosis (TB) in pregnant and non-pregnant women of reproductive age: Findings from an observational study in Pune, India. Poster Presentation. 51st Union World Conference on Lung Health...

An RNA signature for TB risk in pregnant women: A prospective cohort study from India

Post Date: 
2020-10-20
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Mathad J, Bhosale R, Barreto-Duarte B, Alexander M, Kulkarni V, Nathella PK, Andrade B, Gupta A. Polyfunctional T-cells and IL-2 production decrease in pregnant women with latent TB. TB Science 2020. Virtual. October 20, 2020.

Systemic inflammation in pregnant women with and without latent tuberculosis infection

Post Date: 
2020-10-20
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Naik S, Alexander M, Kumar P, Kulkarni V, Yadana S, Bhosale R, Babu S, Gupta A, Mathad J and Shivakoti R. Systemic inflammation in pregnant women with and without latent tuberculosis infection. Poster Presentation. 51st Union World Conference on Lung Health. Virtual Conference. October 20-24, 2020.

Polyfunctional T-cells and IL-2 production decrease in pregnant women with latent TB

Post Date: 
2020-10-20
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Mathad J, Bhosale R, Barreto-Duarte B, Alexander M, Kulkarni V, Nathella PK, Andrade B, Gupta A. Polyfunctional T-cells and IL-2 production decrease in pregnant women with latent TB. TB Science 2020. Virtual. October 20, 2020.

Comparison of neurocognitive assessment in children with TB Meningitis and healthy controls in Pune, India

Post Date: 
2020-10-20
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Nimkar S, Joshi S, Kinikar A, Valvi C, Gupte N, Thakur KT, Suryavanshi N, Mave V, Dooley KE, Arenivas A. Comparison of neurocognitive assessment in children with TB Meningitis and healthy controls in Pune, India. Poster Presentation. 51st Union World Conference on Lung Health. Virtual Conference...

Blood-based biomarkers of tuberculosis in children integrating metabolomic and transcriptomic data

Post Date: 
2020-10-20
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Tornheim JA, Paradkar M, Fukutani KF, Kinikar A, Mave V, Andrade BB, Gupta A, Karakousis PC. Blood-based biomarkers of tuberculosis in children integrating metabolomic and transcriptomic data. TB Science 2020. Virtual. October 20, 2020.

Prevalence and Incidence of Tuberculosis Infection and Disease Among Household Contacts Exposed to Rifampin-resistant/Multidrug resistant Tuberculosis (RR/MDR-TB)

Post Date: 
2020-07-08
Gupta A, Wu X, Kim S, Naini L, Hughes M, Dawson R, Gaikwad S, Sanchez J, Mendoza A, Smith B, Shah S, Hesseling A, Churchyard G, Swindells S for the ACTG/IMPAACT PHOENIx feasibility study team. Prevalence and Incidence of Tuberculosis Infection and Disease Among Household Contacts Exposed to...

Predictors of tuberculosis infection in MDR-TB household contacts ≥15 years old.

Post Date: 
2020-03-11
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Countries: 
Kim S , Gupta A, Wu X, Hughes M, Dawson R, Mave V, Kumarasamy, Smith B, Rustomgee R, Shah NS, Hesseling A, Swindells S, Churchyard G for the ACTG/IMPAACT A5300/I2003 PHOENIx Feasibility Study Team. Predictors of tuberculosis infection in MDR-TB household contacts ≥15 years old. Presented at: CROI...

Rifapentine pharmacokinetics and safety in pregnant women with and without HIV on 3HP

Post Date: 
2020-03-11
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Countries: 
Mathad JS , Savic RM, Britto P, Wiesner L, Townley E, Chakhtoura N, Bradford S, Patil S, Vhembo T, Lespinasse D, Langat D, Werarak P, Kamthunzi P, Gupta A, Dooley KE. Rifapentine pharmacokinetics and safety in pregnant women with and without HIV on 3HP. Presented at: CROI 2020. Boston, MA; March 8-...

Randomized trial of HIV-ASSIST versus guidelines for ART selection by trainees

Post Date: 
2020-03-10
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Ramirez J, Maddali M, Nematollahi S, Li JZ, Shah M. Randomized trial of HIV-ASSIST versus guidelines for ART selection by trainees. Presented at: CROI 2020. Boston, MA: March 8-11, 2020.

Effect of rifamycins on pretomanid exposure in patients with pulmonary TB

Post Date: 
2020-03-10
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Countries: 
Abdelwahab MT , Ignatius E, Denti P, Dooley KE, Gupte N, Dawson R, Barnes G, Narunsky K, Hendricks B. Effect of rifamycins on pretomanid exposure in patients with pulmonary TB. (ID 3688). Presented at: CROI 2020. Boston, Massachusetts. March 8-11, 2020.

“Stylish Man” cluster RCT to increase male circumcision for adult men ≥ 19, Uganda

Post Date: 
2020-03-10
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Countries: 
Wawer M , Kigozi G, Mugamba S, Zikusooka A, Kagaayi J, Serwadda D, Ndyanabo A, Ssekubugu R, Sseasanvu J, Chang LW, Gray RH. “Stylish Man” cluster RCT to increase male circumcision for adult men ≥ 19, Uganda. Presented at: CROI 2020. Boston, MA; March 8-11, 2020.

Factors associated with gestational diabetes in HIV+ and HIV- women in Pune, India

Post Date: 
2020-03-09
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Countries: 
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Clinical Sites: 
Chebrolu P , Alexander M, Bhosale R, Naik S, Patil N, Gupta A, Mathad J. Factors associated with gestational diabetes in HIV+ and HIV- women in Pune, India. Presented at: CROI 2020. Boston, Massachusetts. March 8-11, 2020.

An mHealth CHW intervention trials in an HIV hyperendemic community in Rakai, Uganda

Post Date: 
2020-03-09
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Countries: 
Chang LW , Mbabali I, Kong X, Amico R, Kennedy CE, Nalugoda F, Anok A, Serwadda D, Ssekasanvu J, Quinn TC, Reynolds SJ, Gray RH, Wawer M, Hutton H, Nakigozi G. An mHealth CHW intervention trials in an HIV hyperendemic community in Rakai, Uganda. Presented at: CROI 2020. Boston, MA; March 8-11, 2020.

Geographic and Individual Risk Factors for TB or Death in the Brief-TB Trial (A5279)

Post Date: 
2020-03-09
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Clinical Sites: 
Riviere C , Juste MAJ, Ramchandani R, Gupta A, Benson CA, Masheto G, Supparatpinyo K, Mohapi L, da Silva Escada RO, Mngqibisa R, Kanyama C, Langat D, Swindells S, Chaisson RE, for the A5279/BRIEF TB Study Team. Geographic and Individual Risk Factors for TB or Death in the Brief-TB Trial (A5279)...

Population-level HIV viral load varies by gender, age, and location in Rakai, Uganda

Post Date: 
2020-03-09
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Countries: 
Kyle I , Kagaagi J, Kigozi G, Nakigozi G, Ssekbugu R, Nalugoda F, Grabowski MK, Chang LW, Wawer M, Serwadda D, Gray RH, Quinn T, Reynolds SJ, Rattman O for the Rakai Health Sciences Program. Population-level HIV viral load varies by gender, age, and location in Rakai, Uganda. Presented at: CROI...

Waxing and waning HIV risk: Dynamics of PrEP eligibility in Rakai, Uganda

Post Date: 
2020-03-09
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Countries: 
Ssempijja V, Ssekubugu R, Kigozi G, Kakigozi G, Kagaayi J, Lutalo T, Ndyanabo A, Ekstrom AM, Serwadda D, Quinn TC, Gray RH, Wawer M, Chang LW, Reynolds SJ. Waxing and waning HIV risk: Dynamics of PrEP eligibility in Rakai, Uganda. Presented at: CROI 2020. Boston, MA; March 8-11, 2020.

Tuberculosis preventive therapy should be considered for all household contacts of pulmonary TB patients in India

Post Date: 
2020-02-07
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Countries: 
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Clinical Sites: 
Paradkar M, Chandrasekara P, Jain D, Shivakumar SVBY, Thiruvengadan K, Gupte AN, Thomas B, Kinikar A, Sekar K, Bharadwaj R, Dolla CK, Gaikwad S, Elilarasi S, Lokhande R, Reddy D, Murali L, Kulkarni V, Pradhan N, Hanna LE, Pattabiraman S, Kohli R, Nayagam R, Suryavanshi N, Shrinivasa BM, Cox SR,...

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Experts say COVID-19 mutations are normal

Post Date: 
2021-01-15
Dr. Robert Bollinger: “... As with any virus, changes are something to be watched, to ensure that testing and vaccines are still effective.

Study identifies need to improve patient retention in the National TB Elimination Programme, highlights patients’ trust relationship with private providers

Post Date: 
2021-11-02
Source: 
indianexpress.com
Study identifies need to improve patient retention
The study identified the need to improve patient retention in the NTEP and highlight patients' trust relationship with private providers

Irvin and Page Selected for JHM Levi Watkins, Jr. Mentorship Program

Post Date: 
2021-11-01
Source: 
hopkinsmedicine.org
Drs. Risha Irvin and Kathleen Page
Drs. Risha Irvin and Kathleen Page, associate professors in the Division of ID, have been selected as “Protégés” for the inaugural JHM Levi Watkins, Jr. Mentorship Program.

Johns Hopkins Medicine Team Creates Model to Help Show Path Toward Ending HIV Nationwide

Post Date: 
2021-09-24
Dr. Maunank Shah
A new Johns Hopkins Medicine mathematical model to predict how the human immunodeficiency virus (HIV) spreads in urban areas...

CURE ID Moves to Automated Data Collection in Light of COVID Pandemic

Post Date: 
2021-07-13
Dr. Matt Robinson
Drs. Matt Robinson is leading JHU efforts in this FDA program, and Robert Bollinger and Jane McKenzie-White helped launch it before COVID.

Hopkins Tool Predicts How Hospitalized COVID Patients Will Fare

Post Date: 
2021-03-31
Source: 
Fox 45 News (Baltimore)
Dr. Matthew Robinson
Fox New 45 (Baltimore): Dr. Matt Robinson discusses the SCARP tool, which can predict patients' risk of severe COVID disease and death.

Innovation During Times of Change  |  2020 Annual Report

Post Date: 
2021-03-30
2020 Annual Report
2020 was a year like no other. Learn what CCGHE discovered in our Annual Report.

Experts concerned over pockets of covid among unvaccinated minorities

Post Date: 
2021-03-03
Source: 
Sierra Leone Times
Dr. Kathleen Page
Dr. Page: "If Latinos and Blacks are not receiving vaccinations, the consequences could be troubling for public health."

World Renowned Infectious Disease Expert on CDC's New School Guidelines.

Post Date: 
2021-02-16
Source: 
Leslie Marshall Show
Dr. Robert Bollinger
Leslie Marshall interviews Dr. Robert Bollinger on CDC's New School Guidelines.

Will the New COVID-19 Variants Increase Reinfection Rates?

Post Date: 
2021-02-16
Source: 
VeryWellHealth
Dr. Robert Bollinger
"While the mutations don’t mean much in terms of how the virus functions, if the mutations lead to a change in how the virus works, then we pay more attention to it."

State of Maryland Launches Public Outreach and Equity Campaign to Promote Vaccine Confidence

Post Date: 
2021-02-05
Source: 
The Southern Maryland Chronicle
Dr. Kathleen Page
The State of Maryland today launched its grassroots public outreach and equity campaign to promote vaccine confidence. GoVAX encourages all Marylanders to protect themselves...

COVID-19 Strain Variants, Ramping Up Vaccinations to Get to Herd Immunity

Post Date: 
2021-01-27
Source: 
Leslie Marshall Show
Dr. Robert Bollinger
Leslie and Dr. Bollinger discuss the latest news surrounding COVID-19, including: Moderna announcing that its COVID-19 vaccine is effective against new...

Doctors Explain The Risks If You Miss Your Second Vaccine Appointment

Post Date: 
2021-01-27
Source: 
Bustle
Dr. Robert Bollinger
Dr. Robert Bollinger: "You could be less protected against COVID, for a shorter period, or it could also give the virus time and space to mutate."

New strains of COVID swiftly moving through the US need careful watch, scientists say

Post Date: 
2021-01-25
Source: 
USATODAY
Dr. Robert Bollinger
Instead of perfectly copying its 29,811 bases, the four-letter alphabet used to describe its genetic code, a wrong letter sneaks in.

VERIFY: What do we know about the coronavirus strain in South Africa?

Post Date: 
2021-01-25
Source: 
Radio Health Journal
Dr. Robert Bollinger
Here’s what we know about the strain found in South Africa. According to Dr. Bollinger, it looks to be more contagious than the original. “That's true, not just about the South African variant...

Covid Vaccination Incentives: The Risks And Rewards For Employers

Post Date: 
2021-01-16
Source: 
Forbes
Dr. Robert Bollinger
Dr. Bob Bollinger: “To stop this epidemic and get us all back to a new normal as soon as possible, we will need all segments of society to increase community uptake of vaccination[s]."

Experts say COVID-19 mutations are normal

Post Date: 
2021-01-15
Source: 
messenger-inquirer.com
Dr. Robert Bollinger
Dr. Robert Bollinger: “... As with any virus, changes are something to be watched, to ensure that testing and vaccines are still effective.

A New Strain of Coronavirus: What You Should Know

Post Date: 
2021-01-06
Source: 
hopkinsmedicine.org
Dr. Robert Bollinger
Dr. Bollinger: "All viruses mutate over time, some more than others. For example, flu viruses change often, which is why doctors recommend that you get a flu shot every year."

Research Story Tip: Grants, Management Roles Keep Johns Hopkins A Leader In Hiv/Aids Clinical Trial Research

Post Date: 
2020-12-08
Research Story Tip
Researchers at Johns Hopkins Medicine learned that they now have an enhanced opportunity to help move the world toward a day when that observance is rendered obsolete.

Research Update: TB Trials Conducted by JHU-India Team Will Shorten Drug-Susceptible TB Treatment for Children and Adults

Post Date: 
2020-12-07
Research Updated
Reporting from the virtual 51st Union Conference on Lung Health, the World Health Organization (WHO) and the U.S. Centers for Disease Control and Prevention (CDC) announced promising findings from 2 TB trials

Is It a Cold, the Flu, or COVID-19?

Post Date: 
2020-10-12
Source: 
Everyday Health
Dr. Natasha Chida
Everydat Health: Dr. Natasha Chida: "...80 percent of people who get COVID-19 develop mild symptoms that resemble those of a cold.”

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