Research News

Zika Surveillance Among Pregnant Women in India

India leads the world in dengue cases. CCGHE researchers are keeping an eye on Zika among pregnant women, which is transmitted by the same mosquito & can cause devastating birth defects.

Sepsis among newborns in the neonatal intensive care unit (NICU) is a big problem in India, and a complex one to untangle.

Clinical Research

We work with scientists and practitioners around the world to conduct clinical trials and observational studies that improve prevention and treatment of many grave health issues affecting resource-limited regions, including HIV and tuberculosis.
 
We have formal research partnerships with the following institutions:
 
 

High HIV prevalence among a high-risk subgroup of women attending sexually transmitted infection clinics in Pune, India

Post Date: 
2006-01-01
Publication: 
Journal of Acquired Immune Deficiency Syndromes
Country: 
Objectives: To investigate changes over a decade in prevalence and correlates of HIV among high-risk women attending sexually transmitted infection (STI) clinics in Pune, India, who deny a history of commercial sex work (CSW). Methods: From 1993 to 2002, 2376 women attending 3 STI clinics in Pune...

Correlates and trend of HIV prevalence among female sex workers attending sexually transmitted disease clinics in Pune, India (1993-2002)

Post Date: 
2006-01-01
Publication: 
Journal of Acquired Immune Deficiency Syndromes
Country: 
In India, substantial efforts have been made to increase awareness about HIV/AIDS among female sex workers (FSWs). We assessed the impact of awareness regarding safe sex in a cohort of FSWs by studying trends in HIV prevalence, sexually transmitted diseases (STDs), and risk behaviors measured from...

Mycobacterial-induced potentiation of type 1 immune responses and protection against malaria is host-specific

Post Date: 
2005-12-15
Publication: 
Infection and Immunity
Malaria and tuberculosis are endemic in many regions of the world, and coinfection with the two pathogens is common. In this study, we examined the effects of long- and short-term infection with Mycobacterium tuberculosis on the course of a lethal form of murine malaria in resistant (C57BL/6) and...

Adult botulism type F in the United States, 1981-2002

Post Date: 
2005-12-13
Publication: 
Neurology
Background: Clostridium botulinum neurotoxin types A, B, and E cause most cases of the paralytic disease botulism. Little is known about the epidemiology, clinical features, or microbiology of botulism type F. Methods: Cases of adult type F botulism were identified by review of data collected by...

Antifungal interventions for the primary prevention of cryptococcal disease in adults with HIV

Post Date: 
2005-07-20
Publication: 
Cochrane Database of Systematic Reviews
Infection with the human immunodeficiency virus (HIV) leads to progressive destruction and weakening of the body's immune system. Patients with advanced HIV disease are vulnerable to various diseases, called opportunistic infections (OIs), which most people with normal immune systems are protected...

Genetic diversification and recombination of HIV type 1 group M in Kinshasa, Democratic Republic of Congo

Post Date: 
2005-07-15
Publication: 
AIDS Research and Human Retroviruses
As the HIV-1 pandemic becomes increasingly complex, the genetic characterization of HIV strains bears important implications for vaccine research. To better understand the molecular evolution of HIV-1 viral diversity, we performed a comparative molecular analysis of HIV strains collected from high-...

Necrotizing enterocolitis associated with Clostridium perfringens type A in previously healthy North-American adults

Post Date: 
2005-07-15
Publication: 
Journal of the American College of Surgeons
Background: Necrotizing enteritis associated with Clostridium perfringens type C ("pigbel") is a well-known syndrome in severely protein-deprived populations in the Pacific. It is exceedingly rare in the developed world. C perfringens type A is a common cause of acute gastroenteritis and, in a...

Antimicrobial-resistant Shigella sonnei: Limited antimicrobial treatment options for children and challenges of interpreting in vitro azithromycin susceptibility

Post Date: 
2005-06-15
Publication: 
Journal of Pediatric Infectious Diseases
Background: Antimicrobial-resistant Shigella sonnei is a growing problem in the United States and poses treatment challenges particularly among children. Azithromycin is recommended as an alternative oral agent for shigellosis. Methods: All isolates of Shigella submitted to Johns Hopkins clinical...

IJMR Special Issue on HIV/AIDS: Editorial overview

Post Date: 
2005-04-15
Publication: 
Indian Journal of Medical Research
Country: 
No summary available online

High-risk behaviour in young men attending sexually transmitted disease clinics in Pune, India.

Post Date: 
2005-04-15
Publication: 
AIDS Care
Country: 
The present study reports sexual risk factors associated with HIV infection among men attending two sexually transmitted disease (STD) clinicsin Pune, India and compares these behaviours between young and older men. Between April 1998 and May 2000, 1872 STD patients were screened for HIV infection...

Making the choice: the translation of global HIV and infant feeding policy to local practice among mothers in Pune, India

Post Date: 
2005-04-15
Publication: 
The Journal of Nutrition
Country: 
In 2003, India had over 5.1 million infected individuals living with HIV/AIDS. The percentage of all HIV cases attributed to perinatal transmission has been increasing steadily from 0.33% of total cases in 1999 to 2.80% in 2004. Recent statistics indicate that over 130,000 infants have been...

Sex-based differences in T lymphocyte responses in HIV-1-seropositive individuals

Post Date: 
2005-03-15
Publication: 
Journal of Infectious Diseases
Sex-based differences in the levels of human immunodeficiency virus 1 (HIV-1) RNA in plasma could be associated with differences in the strength of HIV-1-specific CD8(+) T cell responses. CD8(+) effector responses in 18 men and 15 women were measured 0-2 years (time A) and 5-7 years (time B) after...

Correlates of HIV vaccine trial participation: an Indian perspective

Post Date: 
2005-02-03
Publication: 
Vaccine
Country: 
Successful conduct of HIV vaccine trials in a population of great cultural diversity like India could be a challenge. Concerns, knowledge gaps and willingness to participate in future HIV vaccine trials were studied among 349 patients attending three sexually transmitted infections clinics and one...

Limited evolution in the HIV type1 pol region among acute seroconverters in Pune, India.

Post Date: 
2005-01-15
Publication: 
AIDS Research and Human Retroviruses
Country: 
India has the second largest burden of HIV-1-infected persons worldwide. Access to antiretroviral drugs in India is increasing. We analyzed HIV-1 protease and reverse transcriptase sequences in 12 acute seroconverters from Pune, India, and evaluated HIV-1 evolution in these individuals over time...

An international outbreak of salmonellosis associated with raw almonds contaminated with a rare phage type of Salmonella enteriditis.

Post Date: 
2005-01-15
Publication: 
Journal of Food Protection
During the winter of 2000 to 2001, an outbreak due to Salmonella Enteritidis (SE) phage type 30 (PT30), a rare strain, was detected in Canada. The ensuing investigation involved Canadian and American public health and food regulatory agencies and an academic research laboratory. Enhanced laboratory...

Profile of bone marrow examination in HIV/AIDS patients to detect opportunistic infections, especially tuberculosis

Post Date: 
2005-01-15
Publication: 
iIndian Journal of Pathology and Microbiology
Country: 
Morphological evaluation of 140 bone marrow aspirations received in haematopathology laboratory with serologically established HIV infection, along with other relevant special haematological tests, was done during 1st Jan 1999 - 31st Dec 2002 at state government run tertiary care General Hospital...

Profile of bone marrow examination in HIV/AIDS patients to detect opportunistic infections, especially tuberculosis.

Post Date: 
2005-01-15
Publication: 
iIndian Journal of Pathology and Microbiology
Country: 
Morphological evaluation of 140 bone marrow aspirations received in haematopathology laboratory with serologically established HIV infection, along with other relevant special haematological tests, was done during 1st Jan 1999 - 31st Dec 2002 at state government run tertiary care General Hospital...

An international outbreak of salmonellosis associated with raw almonds contaminated with a rare phage type of Salmonella enteriditis

Post Date: 
2005-01-15
Publication: 
Journal of Food Protection
Country: 
During the winter of 2000 to 2001, an outbreak due to Salmonella Enteritidis (SE) phage type 30 (PT30), a rare strain, was detected in Canada. The ensuing investigation involved Canadian and American public health and food regulatory agencies and an academic research laboratory. Enhanced laboratory...

Limited evolution in the HIV type 1 pol region among acute seroconverters in Pune, India

Post Date: 
2005-01-15
Publication: 
AIDS Research and Human Retroviruses
Country: 
India has the second largest burden of HIV-1-infected persons worldwide. Access to antiretroviral drugs in India is increasing. We analyzed HIV-1 protease and reverse transcriptase sequences in 12 acute seroconverters from Pune, India, and evaluated HIV-1 evolution in these individuals over time...

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HIV in India

Post Date: 
2009-05-04
Presentation Location: 
Baltimore, MD
Country: 
Event & Convener: 
Johns Hopkins University AIDS Alliance
Presentation

HIV pathogenesis and implications for acquired resistance

Post Date: 
2009-04-30
Presentation Location: 
Montevideo, Uruguay
Event & Convener: 
Facultad de Ciencias (University of Biological Sciences)
Facultad de Ciencias

TB in pregnancy and novel TB diagnostics

Post Date: 
2009-04-28
Presentation Location: 
Pune, India
Event & Convener: 
BJ Medical College Grand Rounds. BJ Medical College
Presentation

Collaborative Leadership through Effective Networks

Post Date: 
2009-04-21
Presentation Location: 
Kampala, Uganda
Event & Convener: 
Infectious Disease Summit
Presentation

Information Technology and Distance Learning and UbuntuNet and Broadband Connectivity in Four African Countries

Post Date: 
2009-04-17
Presentation Location: 
Nairobi, Kenya
Event & Convener: 
Consortium Workshop: Training Future Leaders in Global Health
Presentation

Global Health Education - Where in the world are we?

Post Date: 
2009-04-03
Presentation Location: 
Seattle, WA
Event & Convener: 
Annual GHEC Conference
Presentation

Update on HIV Resistance

Post Date: 
2009-03-31
Presentation Location: 
San Salvador, El Salvador
Event & Convener: 
COMISCA (Consejos de Ministerios de Salud de Centroamerica- Counsel of Central American Ministries of Health). Renaissance Hotel
Presentationi

PMTCT, infant feeding and response to ART treatment and resistance in women and children

Post Date: 
2009-03-26
Presentation Location: 
Maseru, Lesotho
Event & Convener: 
US State Department Workshop. Baylor Center for Excellence Pediatric Hospital
Presentation

Global HIV: Top Ten Developments of the Past Year and Prevention and Treatment of HIV in South Asia: Challenges and Opportunities

Post Date: 
2009-01-30
Presentation Location: 
Tampa, FL
Event & Convener: 
University of South Florida
Presentation

WHISC presentation of P1078

Post Date: 
2008-12-07
Presentation Location: 
Baltimore, MD
Event & Convener: 
IMPAACT Meeting
Presentation

Early mortality in HIV treatment and TB empiric therapy: Weighing the risks and benefits of an empiric TB strategy

Post Date: 
2008-12-05
Presentation Location: 
Baltimore, MD
Event & Convener: 
ACTG Meeting
Presentation

Update on opportunistic infections and IRIS

Post Date: 
2008-12-03
Presentation Location: 
Wilmington, DE
Event & Convener: 
Mid-Atlantic AIDS Education Training. Wilmington Hospital
Presentation

World AIDS day for African students

Post Date: 
2008-12-02
Presentation Location: 
Washington, DC
Event & Convener: 
US State Department Live Webcast
Presentation

Global Perspective of HIV

Post Date: 
2008-12-01
Presentation Location: 
Baltimore, MD
Event & Convener: 
Caring for the City of HIV, World AIDS Day Celebration. Pastoral Care at the Johns Hopkins Hospital. The Johns Hopkins Hospital
Pastoral Care at the Johns Hopkins Hospital

Global epidemiology and its impact on the Macroeconomics of Countries

Post Date: 
2008-10-28
Presentation Location: 
Philadelphia, PA
Event & Convener: 
University of Pennsylvania: Wharton School
Presentation

Perspectives on Health Care Delivery in Latin America

Post Date: 
2008-09-30
Presentation Location: 
Baltimore, MD
Event & Convener: 
Latin American Student Society. Johns Hopkins Bloomberg School of Public Health
Presentation

Telemedicine in Resource Limited Countries

Post Date: 
2008-09-25
Presentation Location: 
Washington, DC
Event & Convener: 
Children’s National Medical Center
Presentation

Community-based HIV Care

Post Date: 
2008-09-09
Presentation Location: 
Cambridge, MA
Event & Convener: 
HIV Online Provider Education (H.O.P.E.) Conference. Harvard University Center for AIDS Research
Presentation

Ceftriaxone-resistant Salmonella

Post Date: 
2008-06-21
Presentation Location: 
Kuala Lumpur, Malaysia
Event & Convener: 
International Conference on Infectious Diseases
Presentation

Tuberculosis in Pregnancy

Post Date: 
2008-06-06
Presentation Location: 
Rockville, MD
Event & Convener: 
Workshop on Research Priorities for Pediatric Tuberculosis. NIAID/NICHD
Presentation

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