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Study shows success with TB therapy observation conducted via video instead of via in-person clinic visits.

Children in Maharashtra India

Trials: Evidence for TB treatment in kids is largely based on adult studies. The SHINE study aims to fix this

Clinical Research

Leadership
Dr. Amita Gupta of Johns Hopkins is Principal Investigator for the Indo-JHU Clinical Research Partnership based out of CCGHE. Research is directed locally in India out of the BJGMC-JHU Clinical Research Site by Dr. Vidya Mave, a Hopkins faculty member who lives in Pune. Dr. Nikhil Gupte is the Lead Biostatistician and Deputy Director and Dr. Nishi Suryavanshi is Clinical Site Coordinator and Deputy Director. Research is conducted in collaboration with the following institutions:
 
 

Nevirapine resistance and breast-milk HIV transmission: effects of single and extended-dose nevirapine prophylaxis in subtype C HIV-infected infants

Post Date: 
2009-01-01
Publication: 
PLOS One
Country: 
Background: Daily nevirapine (NVP) prophylaxis to HIV-exposed infants significantly reduces breast-milk HIV transmission. We assessed NVP-resistance in Indian infants enrolled in the “six-week extended-dose nevirapine” (SWEN) trial who received single-dose NVP (SD-NVP) or SWEN for prevention of...

Traditional Indian medicine and homeopathy for HIV/AIDS: a review of the literature

Post Date: 
2008-12-22
Publication: 
AIDS Research and Therapy
Country: 
Background: Allopathic practitioners in India are outnumbered by practitioners of traditional Indian medicine and homeopathy (TIMH), which is used by up to two-thirds of its population to help meet primary health care needs, particularly in rural areas. India has an estimated 2.5 million HIV...

Neutralizing antibody responses in recent seroconverters with HIV-1 subtype C infections in India

Post Date: 
2008-10-25
Publication: 
AIDS Research and Human Retroviruses
Country: 
The longitudinal heterologous neutralization response against two HIV-1 subtype C isolates was studied in 33 ART-naive individuals recently infected with HIV-1 subtype C from India. Seven of 33 (21%) seroconverters demonstrated a consistent response against both isolates (65-100% neutralization),...

High risk for occupational exposure to HIV and utilization of post-exposure prophylaxis in a teaching hospital in Pune, India

Post Date: 
2008-10-21
Publication: 
BMC Infectious Diseases
Country: 
Background: The risk for occupational exposure to HIV has been well characterized in the developed world, but limited information is available about this transmission risk in resource-constrained settings facing the largest burden of HIV infection. In addition, the feasibility and utilization of...

Neisseria gonorrhea and Chlamydia trachomatis among Human Immunodeficiency Virus-infected women

Post Date: 
2008-10-15
Publication: 
Sexually Transmitted Diseases
Country: 
In this study, we determine risk factors for CT and GC infection in women receiving HIV continuity care using data from the Johns Hopkins HIV Clinical Cohort. The Johns Hopkins HIV Clinical Cohort is a longitudinal observational study of adult patients (≥18 years old) in HIV care in the Johns...

Repeated pregnancy in HIV positive Indian women with known HIV status

Post Date: 
2008-09-29
Publication: 
AIDS Care
Country: 
HIV-positive women of reproductive age face challenges in decision making related to pregnancy. Understanding factors influencing repeat pregnancies in women with known HIV status are necessary to guide interventions and counseling strategies to better inform and support them. We compared three...

The Indian pediatric HIV epidemic: a systematic review

Post Date: 
2008-09-15
Publication: 
Current HIV Research
Country: 
Despite an estimated 70,000 Indian children living with HIV infection, little is known about India's pediatric HIV epidemic. Generalizations about epidemiology, natural history, and treatment outcomes from other resource-limited settings (RLS) may be inaccurate for several biologic and social...

Incidence of common opportunistic infections in HIV-infected individuals in Pune, India: analysis by stages of immunosuppression represented by CD4 counts

Post Date: 
2008-07-02
Publication: 
International Journal of Infectious Diseases
Background: Opportunistic infections (OIs) influence the morbidity and mortality due to HIV infections. Data from India on the incidence of OIs among HIV-infected individuals by stages of immunodeficiency are scarce. Methods: Between September 2002 and November 2004, HIV-infected individuals were...

Timing of therapy for latent tuberculosis infection among immigrants presenting to a U.S. public health clinic: a retrospective study

Post Date: 
2008-05-12
Publication: 
BMC Public Health
Country: 
Background: In the U.S. more than half of incident tuberculosis (TB) cases occur in immigrants. Current guidelines recommend screening and treatment for latent TB infection (LTBI) within 5 years of arrival to the U.S. This study evaluates the timing of LTBI therapy among immigrants presenting for...

Telecommunications and health care: An HIV/AIDS warmline for communication and consultation in Rakai, Uganda

Post Date: 
2008-04-25
Publication: 
Journal of the International Association of Providers of AIDS Care
Country: 
Hotlines and warmlines have been successfully used in the developed world to provide clinical advice; however, reports on their replicability in resource-limited settings are limited. A warmline was established in Rakai, Uganda, to support an antiretroviral therapy program. Over a 17-month period,...

Responding to the human resource crisis: Peer health workers, mobile phones, and HIV care in Rakai, Uganda.

Post Date: 
2008-03-15
Publication: 
AIDS Patient Care and STDs
Country: 
Dear Editor: Two challenges to successful antiretroviral therapy (ART) scale-up in resource-limited settings (RLS) are human resource and healthcare infrastructure limitations.1 We read with interest the modeling study by Bärnighausen et al. which describes the complexities of ensuring adequate...

Low utilization of HIV testing during pregnancy: what are the barriers to HIV testing for women in rural India?

Post Date: 
2008-02-01
Publication: 
Journal of Acquired Immune Deficiency Syndromes
Country: 
Introduction: Sixty percent of India's HIV cases occur in rural residents. Despite government policy to expand antenatal HIV screening and prevention of maternal-to-child transmission (PMTCT), little is known about HIV testing among rural women during pregnancy. Methods: Between January and March...

Modeling maternal infant HIV transmission in the presence of breast-feeding with an imperfect test

Post Date: 
2007-12-15
Publication: 
Biometrics
Country: 
An important public health question is to determine the probabilities of perinatal HIV transmission and when it occurs, whether antepartum, intrapartum, or postpartum through breastfeeding. However, this is a difficult problem because the presence of HIV infection in an infant can only be...

Selenium and HIV-1: Hope or hype?

Post Date: 
2007-12-10
Publication: 
Archives of Internal Medicine
We read with great interest the article by Hurwitz et al on the impact of selenium supplementation in patients infected with human immunodeficiency virus type 1 (HIV-1). Studies examining the association between micronutrients and HIV, particularly prospective studies, have been limited to date...

Nurses’ health education program in India increases HIV knowledge and reduces fear

Post Date: 
2007-11-30
Publication: 
Journal of the Association of Nurses in AIDS Care
Country: 
Few health care facilities are adequately prepared to manage and care for HIV/AIDS patients in India. Nurses play a critical role in patient care but are often ill-equipped to deal with their own fears of occupational risk and handle the clinical aspects of HIV/AIDS care, leading to stigma and...

Low sensitivity of total lymphocyte count as a surrogate marker to identify antepartum and postpartum Indian women who require antiretroviral therapy

Post Date: 
2007-11-01
Publication: 
Journal of Acquired Immune Deficiency Syndromes
Country: 
Background: Some studies support the use of total lymphocyte count (TLC) as a surrogate marker for CD4 cell count to guide antiretroviral therapy (ART) initiation. However, most of these studies have focused on nonpregnant adults. In light of expanding ART access through prevention of mother-to-...

Declining HIV Incidence among patients attending sexually transmitted infection clinics in Pune, India

Post Date: 
2007-08-15
Publication: 
Journal of Acquired Immune Deficiency Syndromes
Country: 
Objective: A recent report suggesting declining HIV transmission rates in southern India has been based on HIV seroprevalence data to estimate HIV incidence. We analyzed HIV incidence rates among 3 cohorts (male, female non-sex worker, female sex worker [FSW]) presenting to sexually transmitted...

Declining HIV infection rates among recently married, pregnant women in Pune, India

Post Date: 
2007-08-15
Publication: 
Journal of Acquired Immune Deficiency Syndromes
Country: 
Background: A single recent study has suggested a decrease in HIV risk for women attending antenatal clinics (ANCs) in southern India. Yet, some have questioned the validity of the Indian national surveillance data and analyses. Previous studies suggest that the only major HIV risk factor for...

Mother-to-child transmission of HIV among women who chose not to exclusively breastfeed their infants in Pune, India

Post Date: 
2007-08-15
Publication: 
Indian Journal of Medical Research
Country: 
Background and Objective: The percentage of HIV cases attributed to mother-to-child transmission (MTCT) has increased several fold in recent years. No reports are available on HIV MTCT rates among HIV-infected choosing not be exclusively breastfeed their infants in India. We examined HIV MTCT rates...

U.S. medical resident familiarity with national tuberculosis guidelines

Post Date: 
2007-08-02
Publication: 
BMC Infectious Diseases
Country: 
Background: The ability of medical residents training at U.S. urban medical centers to diagnose and manage tuberculosis cases has important public health implications. We assessed medical resident knowledge about tuberculosis diagnosis and early management based on American Thoracic Society...

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Alternative Careers in Medicine

Post Date: 
2010-11-06
Presentation Location: 
Washington, DC
Event & Convener: 
Association of American Medical Colleges (AAMC) Annual Meeting
Presentation

Updates in HIV Resistance

Post Date: 
2010-10-31
Presentation Location: 
Panama City, Florida
Event & Convener: 
MINSA (Panamanian Ministry of Health) and Probisida (HIV NGO)
Presentation

Early Mortality Post Antiretroviral Initiation in Low Income Settings

Post Date: 
2010-09-30
Presentation Location: 
New Delhi, India
Event & Convener: 
ICOPA Conference
Presentation

Successful Grant and Paper Writing are Always the Greatest Challenges for Mentor and Mentee

Post Date: 
2010-09-10
Presentation Location: 
Kampala, Uganda
Event & Convener: 
Mentorship Workshop. Makerere University
Presentation

Maternal-child transmission of TB: what do we know?

Post Date: 
2010-07-29
Presentation Location: 
Bethesda, MD
Event & Convener: 
NIH TB Summit
Workshop Panelist and lecturer. Gupta, A.

Nutrition and disease progression Pre- and Post-HAART: can good nutrition delay time to and response to HAART?

Post Date: 
2010-07-27
Presentation Location: 
Washington, DC
Event & Convener: 
Nutrition in Clinical Management of HIV Infected Adolescents (>14 yr) and Adults including Pregnant and Lactating Women: What do we know, what can we do, and where do we go from here? NIH
Presentation

Does HIV-HBV Co-Infection in HIV- infected Pregnant Women have Significant Impact on Infant Clinical Outcomes?

Post Date: 
2010-07-18
Presentation Location: 
Vienna, Austria
Event & Convener: 
International AIDS Conference. AIDS 2010
Presentation.

South Asia Health Issues

Post Date: 
2010-06-24
Presentation Location: 
Arlington, VA
Event & Convener: 
Foreign Service Institute. US State Department
Presentation

Is TB a Risk Factor for Mother-to-Child Transmission of HIV?

Post Date: 
2010-06-11
Presentation Location: 
Baltimore, MD
Event & Convener: 
Annual Scientific Meeting. Johns Hopkins University Center for Tuberculosis Research
Presentation

TB/HIV in women and children: research in India and beyond

Post Date: 
2010-05-26
Presentation Location: 
Baltimore, MD
Country: 
Event & Convener: 
TB Clinical and Epi Lab Meeting. Johns Hopkins University School of Medicine
Presentation

Technology in Other Countries

Post Date: 
2010-05-07
Presentation Location: 
Baltimore, MD
Event & Convener: 
Innovation and Africa Program. University of Maryland
Presentation

Symposium on International Distance Learning and Infectious Diseases

Post Date: 
2010-04-27
Presentation Location: 
Baltimore, MD
Event & Convener: 
Department of Medicine Research Retreat. Johns Hopkins University School of Medicine
Bollinger, R. and Chang, LW

New Strategies to Expand Clinical Care Capacity in Resource-Limited Settings

Post Date: 
2010-04-17
Presentation Location: 
New Haven, CT
Event & Convener: 
Global Health and Innovation Conference. Yale University
Presentationi

The use of Distance Learning Techniques to Support Clinical Care and Laboratory Capacity in Resource-Limited Settings

Post Date: 
2010-03-23
Presentation Location: 
Baltimore, MD
Event & Convener: 
2010 Leadership Conference. Clinical and Laboratory Standards Institute (CLSI)
Clinical and Laboratory Standards Institute (CLSI)

HIV/AIDS and Associated Opportunistic Infections

Post Date: 
2010-01-28
Presentation Location: 
Albuquerque, NM
Event & Convener: 
University of New Mexico
Presentation

Early Mortality post HAART initiation in Low- and Middle-income countries

Post Date: 
2010-01-22
Presentation Location: 
Pune, India
Event & Convener: 
National AIDS Research Institute
Presentation

Beyond current first-line antiretrovirals: need for second-line and newer drugs as well as optimized care

Post Date: 
2010-01-18
Presentation Location: 
Pune, India
Event & Convener: 
Symposium on Policy, Program and Care for HIV/AIDS in India. National AIDS Research Institute.
Symposium on Policy, Program and Care for HIV/AIDS in India

Early Mortality post HAART initiation in Low- and Middle-income countries

Post Date: 
2010-01-13
Presentation Location: 
Pune, India
Event & Convener: 
BJMC Medical Grand Rounds. BJ Medical Center
Presentation

Early Mortality post HAART initiation in Low- and Middle-income countries

Post Date: 
2010-01-10
Presentation Location: 
Chennai, India
Event & Convener: 
National HIV CART Conference
Presentation

World Health Organization (WHO) HIV Treatment Guidelines for Adults and Adolescents: Updates and Insights on the 2009 Revision

Post Date: 
2009-12-17
Presentation Location: 
Washington, DC
Event & Convener: 
Accordia Foundation and Infectious Disease Institute Board Meeting
Presentation

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