Research News

BMC Infectious Diseases: Our survey among TB patients' household contacts with evidence of recent exposure found that knowledge is poor and families are confused about disease transmission.

Johns Hopkins Medicine logo

Study shows success with TB therapy observation conducted via video instead of via in-person clinic visits.

Clinical Research

Leadership
Dr. Amita Gupta of Johns Hopkins is Principal Investigator for the Indo-JHU Clinical Research Partnership based out of CCGHE. Research is directed locally in India out of the BJGMC-JHU Clinical Research Site by Dr. Vidya Mave, a Hopkins faculty member who lives in Pune. Dr. Nikhil Gupte is the Lead Biostatistician and Deputy Director and Dr. Nishi Suryavanshi is Clinical Site Coordinator and Deputy Director. Research is conducted in collaboration with the following institutions:
 
 

Screening for HIV dementia in an HIV, clade C-infected population in India

Post Date: 
2006-02-12
   |   
Countries: 
Publication: 
Journal of Neurovirology
Although human immunodeficiency virus (HIV) clade C virus infects the largest populations worldwide, to date there are no prospective studies reported thus far to determine the incidence or prevalence of HIV dementia in this population. HIV clade C virus is a CCR5-tropic virus and thus...

Rate of hospitalization and inpatient care costs for HIV-1 infected in Pune, India

Post Date: 
2006-02-01
   |   
Countries: 
Publication: 
National Medical Journal of India
Background: The transition of human immunodeficiency virus (HIV) infection to acquired immune deficiency syndrome (AIDS) has begun in India, and an increase in AIDS-related hospitalizations and deaths is an anticipated challenge. We estimated the rates of hospitalization and inpatient care costs...

High HIV prevalence among a high-risk subgroup of women attending sexually transmitted infection clinics in Pune, India

Post Date: 
2006-01-01
   |   
Countries: 
Publication: 
Journal of Acquired Immune Deficiency Syndromes
Objectives: To investigate changes over a decade in prevalence and correlates of HIV among high-risk women attending sexually transmitted infection (STI) clinics in Pune, India, who deny a history of commercial sex work (CSW). Methods: From 1993 to 2002, 2376 women attending 3 STI clinics in Pune...

Correlates and trend of HIV prevalence among female sex workers attending sexually transmitted disease clinics in Pune, India (1993-2002)

Post Date: 
2006-01-01
   |   
Countries: 
Publication: 
Journal of Acquired Immune Deficiency Syndromes
In India, substantial efforts have been made to increase awareness about HIV/AIDS among female sex workers (FSWs). We assessed the impact of awareness regarding safe sex in a cohort of FSWs by studying trends in HIV prevalence, sexually transmitted diseases (STDs), and risk behaviors measured from...

Mycobacterial-induced potentiation of type 1 immune responses and protection against malaria is host-specific

Post Date: 
2005-12-15
Publication: 
Infection and Immunity
Malaria and tuberculosis are endemic in many regions of the world, and coinfection with the two pathogens is common. In this study, we examined the effects of long- and short-term infection with Mycobacterium tuberculosis on the course of a lethal form of murine malaria in resistant (C57BL/6) and...

Adult botulism type F in the United States, 1981-2002

Post Date: 
2005-12-13
Publication: 
Neurology
Background: Clostridium botulinum neurotoxin types A, B, and E cause most cases of the paralytic disease botulism. Little is known about the epidemiology, clinical features, or microbiology of botulism type F. Methods: Cases of adult type F botulism were identified by review of data collected by...

Antifungal interventions for the primary prevention of cryptococcal disease in adults with HIV

Post Date: 
2005-07-20
Publication: 
Cochrane Database of Systematic Reviews
Infection with the human immunodeficiency virus (HIV) leads to progressive destruction and weakening of the body's immune system. Patients with advanced HIV disease are vulnerable to various diseases, called opportunistic infections (OIs), which most people with normal immune systems are protected...

Genetic diversification and recombination of HIV type 1 group M in Kinshasa, Democratic Republic of Congo

Post Date: 
2005-07-15
   |   
Publication: 
AIDS Research and Human Retroviruses
As the HIV-1 pandemic becomes increasingly complex, the genetic characterization of HIV strains bears important implications for vaccine research. To better understand the molecular evolution of HIV-1 viral diversity, we performed a comparative molecular analysis of HIV strains collected from high-...

Necrotizing enterocolitis associated with Clostridium perfringens type A in previously healthy North-American adults

Post Date: 
2005-07-15
Publication: 
Journal of the American College of Surgeons
Background: Necrotizing enteritis associated with Clostridium perfringens type C ("pigbel") is a well-known syndrome in severely protein-deprived populations in the Pacific. It is exceedingly rare in the developed world. C perfringens type A is a common cause of acute gastroenteritis and, in a...

Antimicrobial-resistant Shigella sonnei: Limited antimicrobial treatment options for children and challenges of interpreting in vitro azithromycin susceptibility

Post Date: 
2005-06-15
Publication: 
Journal of Pediatric Infectious Diseases
Background: Antimicrobial-resistant Shigella sonnei is a growing problem in the United States and poses treatment challenges particularly among children. Azithromycin is recommended as an alternative oral agent for shigellosis. Methods: All isolates of Shigella submitted to Johns Hopkins clinical...

IJMR Special Issue on HIV/AIDS: Editorial overview

Post Date: 
2005-04-15
   |   
Countries: 
Publication: 
Indian Journal of Medical Research
No summary available online

High-risk behaviour in young men attending sexually transmitted disease clinics in Pune, India.

Post Date: 
2005-04-15
   |   
Countries: 
Publication: 
AIDS Care
The present study reports sexual risk factors associated with HIV infection among men attending two sexually transmitted disease (STD) clinicsin Pune, India and compares these behaviours between young and older men. Between April 1998 and May 2000, 1872 STD patients were screened for HIV infection...

Making the choice: the translation of global HIV and infant feeding policy to local practice among mothers in Pune, India

Post Date: 
2005-04-15
   |   
Clinical Sites: 
   |   
Countries: 
Publication: 
The Journal of Nutrition
In 2003, India had over 5.1 million infected individuals living with HIV/AIDS. The percentage of all HIV cases attributed to perinatal transmission has been increasing steadily from 0.33% of total cases in 1999 to 2.80% in 2004. Recent statistics indicate that over 130,000 infants have been...

Sex-based differences in T lymphocyte responses in HIV-1-seropositive individuals

Post Date: 
2005-03-15
Publication: 
Journal of Infectious Diseases
Sex-based differences in the levels of human immunodeficiency virus 1 (HIV-1) RNA in plasma could be associated with differences in the strength of HIV-1-specific CD8(+) T cell responses. CD8(+) effector responses in 18 men and 15 women were measured 0-2 years (time A) and 5-7 years (time B) after...

Correlates of HIV vaccine trial participation: an Indian perspective

Post Date: 
2005-02-03
   |   
Countries: 
Publication: 
Vaccine
Successful conduct of HIV vaccine trials in a population of great cultural diversity like India could be a challenge. Concerns, knowledge gaps and willingness to participate in future HIV vaccine trials were studied among 349 patients attending three sexually transmitted infections clinics and one...

Profile of bone marrow examination in HIV/AIDS patients to detect opportunistic infections, especially tuberculosis

Post Date: 
2005-01-15
   |   
Clinical Sites: 
   |   
Countries: 
Publication: 
Indian Journal of Pathology and Microbiology
Morphological evaluation of 140 bone marrow aspirations received in haematopathology laboratory with serologically established HIV infection, along with other relevant special haematological tests, was done during 1st Jan 1999 - 31st Dec 2002 at state government run tertiary care General Hospital...

Profile of bone marrow examination in HIV/AIDS patients to detect opportunistic infections, especially tuberculosis

Post Date: 
2005-01-15
   |   
Clinical Sites: 
   |   
Countries: 
Publication: 
iIndian Journal of Pathology and Microbiology
Morphological evaluation of 140 bone marrow aspirations received in haematopathology laboratory with serologically established HIV infection, along with other relevant special haematological tests, was done during 1st Jan 1999 - 31st Dec 2002 at state government run tertiary care General Hospital...

An international outbreak of salmonellosis associated with raw almonds contaminated with a rare phage type of Salmonella enteriditis

Post Date: 
2005-01-15
   |   
Countries: 
Publication: 
Journal of Food Protection
During the winter of 2000 to 2001, an outbreak due to Salmonella Enteritidis (SE) phage type 30 (PT30), a rare strain, was detected in Canada. The ensuing investigation involved Canadian and American public health and food regulatory agencies and an academic research laboratory. Enhanced laboratory...

Limited evolution in the HIV type 1 pol region among acute seroconverters in Pune, India

Post Date: 
2005-01-15
   |   
Clinical Sites: 
   |   
Countries: 
Publication: 
AIDS Research and Human Retroviruses
India has the second largest burden of HIV-1-infected persons worldwide. Access to antiretroviral drugs in India is increasing. We analyzed HIV-1 protease and reverse transcriptase sequences in 12 acute seroconverters from Pune, India, and evaluated HIV-1 evolution in these individuals over time...

An international outbreak of salmonellosis associated with raw almonds contaminated with a rare phage type of Salmonella enteriditis.

Post Date: 
2005-01-15
Publication: 
Journal of Food Protection
During the winter of 2000 to 2001, an outbreak due to Salmonella Enteritidis (SE) phage type 30 (PT30), a rare strain, was detected in Canada. The ensuing investigation involved Canadian and American public health and food regulatory agencies and an academic research laboratory. Enhanced laboratory...

Pages

Update on HIV Resistance

Post Date: 
2009-03-31
Presentation Location: 
San Salvador, El Salvador
Event & Convener: 
COMISCA (Consejos de Ministerios de Salud de Centroamerica- Counsel of Central American Ministries of Health). Renaissance Hotel
Presentationi

PMTCT, infant feeding and response to ART treatment and resistance in women and children

Post Date: 
2009-03-26
Presentation Location: 
Maseru, Lesotho
Event & Convener: 
US State Department Workshop. Baylor Center for Excellence Pediatric Hospital
Presentation

Global HIV: Top Ten Developments of the Past Year and Prevention and Treatment of HIV in South Asia: Challenges and Opportunities

Post Date: 
2009-01-30
Presentation Location: 
Tampa, FL
Event & Convener: 
University of South Florida
Presentation

WHISC presentation of P1078

Post Date: 
2008-12-07
Presentation Location: 
Baltimore, MD
Event & Convener: 
IMPAACT Meeting
Presentation

Early mortality in HIV treatment and TB empiric therapy: Weighing the risks and benefits of an empiric TB strategy

Post Date: 
2008-12-05
Presentation Location: 
Baltimore, MD
Event & Convener: 
ACTG Meeting
Presentation

Update on opportunistic infections and IRIS

Post Date: 
2008-12-03
Presentation Location: 
Wilmington, DE
Event & Convener: 
Mid-Atlantic AIDS Education Training. Wilmington Hospital
Presentation

World AIDS day for African students

Post Date: 
2008-12-02
Presentation Location: 
Washington, DC
Event & Convener: 
US State Department Live Webcast
Presentation

Global Perspective of HIV

Post Date: 
2008-12-01
Presentation Location: 
Baltimore, MD
Event & Convener: 
Caring for the City of HIV, World AIDS Day Celebration. Pastoral Care at the Johns Hopkins Hospital. The Johns Hopkins Hospital
Pastoral Care at the Johns Hopkins Hospital

Global epidemiology and its impact on the Macroeconomics of Countries

Post Date: 
2008-10-28
Presentation Location: 
Philadelphia, PA
Event & Convener: 
University of Pennsylvania: Wharton School
Presentation

Perspectives on Health Care Delivery in Latin America

Post Date: 
2008-09-30
Presentation Location: 
Baltimore, MD
Event & Convener: 
Latin American Student Society. Johns Hopkins Bloomberg School of Public Health
Presentation

Telemedicine in Resource Limited Countries

Post Date: 
2008-09-25
Presentation Location: 
Washington, DC
Event & Convener: 
Children’s National Medical Center
Presentation

Community-based HIV Care

Post Date: 
2008-09-09
Presentation Location: 
Cambridge, MA
Event & Convener: 
HIV Online Provider Education (H.O.P.E.) Conference. Harvard University Center for AIDS Research
Presentation

Ceftriaxone-resistant Salmonella

Post Date: 
2008-06-21
Presentation Location: 
Kuala Lumpur, Malaysia
Event & Convener: 
International Conference on Infectious Diseases
Presentation

Tuberculosis in Pregnancy

Post Date: 
2008-06-06
Presentation Location: 
Rockville, MD
Event & Convener: 
Workshop on Research Priorities for Pediatric Tuberculosis. NIAID/NICHD
Presentation

An update in opportunistic infections

Post Date: 
2008-05-16
Presentation Location: 
Baltimore, MD
Event & Convener: 
Johns Hopkins HIV Clinical Care Conference
Presentation

An Annual Checkup of South Asia’s Public Health

Post Date: 
2008-05-13
Presentation Location: 
Washington, DC
Event & Convener: 
Foreign Service Institute. U.S. Department of State
Presentation

Antibiotic Management Program

Post Date: 
2008-05-10
Presentation Location: 
Santiago, Chile
Event & Convener: 
Experience and Nococomial Pneumonia and Respiratory Tract Infections and C-difficile. Johns Hopkins Medicine International and Clinic of Condes
Presentation

Update on opportunistic infections

Post Date: 
2008-04-04
Presentation Location: 
Rio de Janeiro, Brazil
Event & Convener: 
Brazil-Hopkins AIDS Conference
Presentation

The Need to Build a Culture and Capacity for Clinical Research within HIV Prevention, Care and Treatment Programs

Post Date: 
2008-04-04
Presentation Location: 
Rio de Janeiro, Brazil
Event & Convener: 
VIII Brasil-Johns Hopkins University on HIV/AIDS. Hotel Sofitel
Presentation

Priorities and Opportunities for Vaccine Development: A Global View

Post Date: 
2008-03-27
Presentation Location: 
Philadelphia, PA
Event & Convener: 
Jefferson Vaccine Center Yearly Retreat. Thomas Jefferson University
Presentation

Pages