Research News

Tuberculosis bacteria
June 25, 2019

NIH Press Release: NIH announces a large international clinical trial to prevent multidrug-resistant TB in children, adolescents, and adults who live with someone who has MDR-TB. CCGHE's Dr. Amita Gupta is a protocol chair.

Clinical Research

Leadership
While we conduct research all over the world, the majority of our work is in India. Our Indo-JHU Clinical Research Partnership is located in Pune and is directed by Dr. Amita Gupta (Baltimore, MD), with onsite direction from Dr. Vidya Mave, Dr. Nishi Suryavanshi, and Dr. Nikhil Gupte (Pune). The Indo-JHU Partnership employs more than 200 people and in addition to our memberships in cosortia with many esteemed Indian research institutions, we have formal agreements with:

 
 

Antifungal interventions for the primary prevention of cryptococcal disease in adults with HIV

Post Date: 
2005-07-20
Publication: 
Cochrane Database of Systematic Reviews
Infection with the human immunodeficiency virus (HIV) leads to progressive destruction and weakening of the body's immune system. Patients with advanced HIV disease are vulnerable to various diseases, called opportunistic infections (OIs), which most people with normal immune systems are protected...

Necrotizing enterocolitis associated with Clostridium perfringens type A in previously healthy North-American adults

Post Date: 
2005-07-15
Publication: 
Journal of the American College of Surgeons
Background: Necrotizing enteritis associated with Clostridium perfringens type C ("pigbel") is a well-known syndrome in severely protein-deprived populations in the Pacific. It is exceedingly rare in the developed world. C perfringens type A is a common cause of acute gastroenteritis and, in a...

Genetic diversification and recombination of HIV type 1 group M in Kinshasa, Democratic Republic of Congo

Post Date: 
2005-07-15
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Publication: 
AIDS Research and Human Retroviruses
As the HIV-1 pandemic becomes increasingly complex, the genetic characterization of HIV strains bears important implications for vaccine research. To better understand the molecular evolution of HIV-1 viral diversity, we performed a comparative molecular analysis of HIV strains collected from high-...

Antimicrobial-resistant Shigella sonnei: Limited antimicrobial treatment options for children and challenges of interpreting in vitro azithromycin susceptibility

Post Date: 
2005-06-15
Publication: 
Journal of Pediatric Infectious Diseases
Background: Antimicrobial-resistant Shigella sonnei is a growing problem in the United States and poses treatment challenges particularly among children. Azithromycin is recommended as an alternative oral agent for shigellosis. Methods: All isolates of Shigella submitted to Johns Hopkins clinical...

IJMR Special Issue on HIV/AIDS: Editorial overview

Post Date: 
2005-04-15
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Countries: 
Publication: 
Indian Journal of Medical Research
No summary available online

High-risk behaviour in young men attending sexually transmitted disease clinics in Pune, India.

Post Date: 
2005-04-15
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Countries: 
Publication: 
AIDS Care
The present study reports sexual risk factors associated with HIV infection among men attending two sexually transmitted disease (STD) clinicsin Pune, India and compares these behaviours between young and older men. Between April 1998 and May 2000, 1872 STD patients were screened for HIV infection...

Making the choice: the translation of global HIV and infant feeding policy to local practice among mothers in Pune, India

Post Date: 
2005-04-15
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Countries: 
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Publication: 
The Journal of Nutrition
In 2003, India had over 5.1 million infected individuals living with HIV/AIDS. The percentage of all HIV cases attributed to perinatal transmission has been increasing steadily from 0.33% of total cases in 1999 to 2.80% in 2004. Recent statistics indicate that over 130,000 infants have been...

Sex-based differences in T lymphocyte responses in HIV-1-seropositive individuals

Post Date: 
2005-03-15
Publication: 
Journal of Infectious Diseases
Sex-based differences in the levels of human immunodeficiency virus 1 (HIV-1) RNA in plasma could be associated with differences in the strength of HIV-1-specific CD8(+) T cell responses. CD8(+) effector responses in 18 men and 15 women were measured 0-2 years (time A) and 5-7 years (time B) after...

Correlates of HIV vaccine trial participation: an Indian perspective

Post Date: 
2005-02-03
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Countries: 
Publication: 
Vaccine
Successful conduct of HIV vaccine trials in a population of great cultural diversity like India could be a challenge. Concerns, knowledge gaps and willingness to participate in future HIV vaccine trials were studied among 349 patients attending three sexually transmitted infections clinics and one...

An international outbreak of salmonellosis associated with raw almonds contaminated with a rare phage type of Salmonella enteriditis.

Post Date: 
2005-01-15
Publication: 
Journal of Food Protection
During the winter of 2000 to 2001, an outbreak due to Salmonella Enteritidis (SE) phage type 30 (PT30), a rare strain, was detected in Canada. The ensuing investigation involved Canadian and American public health and food regulatory agencies and an academic research laboratory. Enhanced laboratory...

Profile of bone marrow examination in HIV/AIDS patients to detect opportunistic infections, especially tuberculosis

Post Date: 
2005-01-15
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Countries: 
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Clinical Sites: 
Publication: 
Indian Journal of Pathology and Microbiology
Morphological evaluation of 140 bone marrow aspirations received in haematopathology laboratory with serologically established HIV infection, along with other relevant special haematological tests, was done during 1st Jan 1999 - 31st Dec 2002 at state government run tertiary care General Hospital...

Profile of bone marrow examination in HIV/AIDS patients to detect opportunistic infections, especially tuberculosis

Post Date: 
2005-01-15
   |   
Countries: 
   |   
Clinical Sites: 
Publication: 
iIndian Journal of Pathology and Microbiology
Morphological evaluation of 140 bone marrow aspirations received in haematopathology laboratory with serologically established HIV infection, along with other relevant special haematological tests, was done during 1st Jan 1999 - 31st Dec 2002 at state government run tertiary care General Hospital...

An international outbreak of salmonellosis associated with raw almonds contaminated with a rare phage type of Salmonella enteriditis

Post Date: 
2005-01-15
   |   
Countries: 
Publication: 
Journal of Food Protection
During the winter of 2000 to 2001, an outbreak due to Salmonella Enteritidis (SE) phage type 30 (PT30), a rare strain, was detected in Canada. The ensuing investigation involved Canadian and American public health and food regulatory agencies and an academic research laboratory. Enhanced laboratory...

Limited evolution in the HIV type 1 pol region among acute seroconverters in Pune, India

Post Date: 
2005-01-15
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Countries: 
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Clinical Sites: 
Publication: 
AIDS Research and Human Retroviruses
India has the second largest burden of HIV-1-infected persons worldwide. Access to antiretroviral drugs in India is increasing. We analyzed HIV-1 protease and reverse transcriptase sequences in 12 acute seroconverters from Pune, India, and evaluated HIV-1 evolution in these individuals over time...

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