Research News

Kathleen Page briefs UN Security Council on Venezuela humanitarian crisis, April 9, 2019

Calling for the declaration of a humanitarian crisis, Dr. Kathleen Page briefed the UN Security Council on Venezuela's Humanitarian Emergency, a recent report by Page and colleagues at Human Rights Watch

Clinical Research

Leadership
Dr. Amita Gupta of Johns Hopkins is Principal Investigator for the Indo-JHU Clinical Research Partnership based out of CCGHE. Research is directed locally in India out of the BJGMC-JHU Clinical Research Site by Dr. Vidya Mave, a Hopkins faculty member who lives in Pune. Dr. Nikhil Gupte is the Lead Biostatistician and Deputy Director and Dr. Nishi Suryavanshi is Clinical Site Coordinator and Deputy Director. Research is conducted in collaboration with the following institutions:
 
 

Association of Lipid Mediators of Inflammation with TB Treatment Outcomes

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2017-08-03
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This study is using stored samples from the Cohort for Tuberculosis Research by the Indo-US Medical Partnership (C-TRIUMPH), under the Regional Prospective Observational Research for Tuberculosis (RePORT) Network, an international TB consortium. Recent studies have shown the significant role that...

Role of Specialized Pro-resolving Mediators (SPMs) on Markers of Inflammation in HIV-infected Adults

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2017-08-03
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Dr. Rupak Shivikoti is leading this study. There has been a surge of recent studies focusing on the role of novel lipid mediators of inflammation called specialized pro-resolving mediators (SPMs). They are produced during inflammation as a negative feedback to resolve inflammation. However, the...

Optimizing Treatment to Improve TBM Outcomes in Children: Substudy on Clinical Profile and CSF Biorepository of the Pediatric Suspected Meningitis Cases

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2017-07-18
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This sub-study is being led by PIs Dr. Kelly Dooley and Dr. Chhaya Valvi. Meningoencephalitis is associated with significant morbidity and mortality. Several viruses, bacteria, and fungal pathogens including Neisseria meningitidis, Streptococcus pneumoniae, Mycobacterium tuberculosis, Herpes...

A5332: Randomized Trial to Prevent Vascular Events in HIV – REPRIEVE

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2017-06-09
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This study is conducted under the AIDS Clinical Trials Group (ACTG) and funded by the U.S. National Institutes of Health. This is a prospective, double-blind, randomized, placebo-controlled, multicenter efficacy study in 6500 subjects, with individual subjects to be followed for up to 72 months...

A5349: Rifapentine-containing Treatment Shortening Regimens for Pulmonary Tuberculosis: A Randomized, Open-label, Controlled Phase 3 Clinical Trial

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2017-06-05
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This study is conducted under the AIDS Clinical Trials Group (ACTG) and funded by the U.S. National Institutes of Health. This is an international, multicenter, randomized, controlled, open-label, 3-arm, phase 3 non-inferiority trial. Primary Objectives: To evaluate the efficacy of a rifapentine-...

Understanding Quality of Life during and Loss to Follow-up from Drug-Resistant Tuberculosis Treatment in Pune, India

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2017-05-15
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This study will examine a) risk factors for loss to follow-up from DR-TB treatment, b) actively trace DR-TB patients lost to follow-up from treatment and c) establish a prospective observational cohort of MDR-TB, XDR-TB and DS-TB patients as well as healthy controls nested within ongoing RNTCP...

Risk Factors for Unfavourable Treatment Outcomes among Multidrug-Resistant Tuberculosis Patients in Public Sector Treatment in Pune

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2017-03-29
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This study is funded and conducted under the U.S. National Institutes of Health, Fogarty International Center. This study seeks to identify risk factors associated with unfavourable treatment outcomes (death, treatment failure, default, XDR-TB) among multidrug-resistant tuberculosis (MDR-TB)...

Biomarkers for Tuberculosis Diagnosis and Treatment Response

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2017-03-24
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This study is conducted by the Cohort for Tuberculosis Research by the Indo-US Medical Partnership (C-TRIUMPH) under the Regional Prospective Observational Research for Tuberculosis (RePORT) Network, an international TB consortium. Aims: To develop non-sputum, blood-based tools for TB diagnosis and...

MDR-TB Free: Monitoring Adverse Effects, Utilizing Resources Optimally, Knowing Resistance Patterns, and Treatment Strategy

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2017-03-24
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This study is also known as MDR-TB MUKT: M onitoring Adverse Effects, U tilizing Resources Optimally, K nowing Resistance Patterns, and T reatment Strategy. Purpose: To establish an observational cohort of MDR-TB cases and household contacts with accompanying biorepository at PD Hinduja National...

Impact of HIV and Diabetes Mellitus on TB Drug Resistance and Recurrence

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2017-03-02
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Tuberculosis (TB) is the leading cause of mortality globally. With increasing burden of HIV and diabetes mellitus (DM), there is a critical need to understand the microbial response and ensuing disease dynamics of TB in the HIV-infected and diabetic host to optimally control TB globally. Among...

Multicenter Study of the Accuracy of the BD MAX MDR-TB Assay for Detection of M. tuberculosis Complex and Mutations Associated with Resistance to Rifampin or Isoniazid

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2017-03-01
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In a multi-country study, we are assessing the accuracy of the BD MAX rapid MDR-TB assay to detect rifampin and isoniazid resistance.

TREAT Asia Pediatric HIV Observational Database

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2017-02-09
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Studies conducted under the TREAT Asia Network and funded by amfAR. TREAT Asia Pediatric HIV Observational Database (TApHOD) is a collaborative observational cohort study of infants, children, and adolescents living with HIV. TApHOD study participants are enrolled and followed at selected TREAT...

TREAT Asia Observational Database

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2017-02-09
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Study conducted under the TREAT Asia Network and funded by amfAR. The TREAT Asia Observational Database's primary study objective is to: Examine HIV natural history, including the relationship between access to ART, demographics, and disease progression; short- and long-term responses to ART;...

Healthcare-Associated Sepsis in the Neonatal Intensive Care Unit in Pune, India

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2017-01-17
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This study is part of CDC's Safe Healthcare, Epidemiology, and Prevention Research Development (SHEPheRD) Program under Domain 7: International HAI and Other Adverse Healthcare Event Prevention. Johns Hopkins neonatologist Dr. Julia Johnson is lead investigator for a systematic study of the...

Shorter Treatment for Minimal TB in Children (SHINE)

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2017-01-17
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This is a multicountry study being conducted in India, South Africa, Uganda, and Zambia. The principal objective is to determine whether the standard 6 month regimen (8 weeks HRZ(E) followed by 16 weeks HR) can be reduced with similar efficacy, to 4 months (8 weeks HRZ(E) followed by 8 weeks HR),...

Bacterial Antimicrobial Resistance Patterns in Pune, India: Substudy on the Introduction of Triage to a Triage Naïve Emergency Department in Pune, India, and the Effects on Patient Flow

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2017-01-01
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Despite state-of-the-art inpatient facilities, Sassoon General Hospital (SGH) in Pune, India, does not currently have a method of triaging the large volume of patients they care for on a daily basis. Based on prior studies in low to middle income countries with underdeveloped emergency medical...

LaMocha: A Mobile Technology to Promote HIV Testing among Immigrant Latino Men

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2016-12-15
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Foreign-born Latino males have a high risk of late HIV diagnosis and presentation to care, which can lead to poor clinical outcomes and ongoing HIV transmission in the community. We propose to evaluate if tailored videos delivered through a tablet by a Latino Health Worker and regular SMS text...

Prevalence and Risk Factors for Oral Cancer among HIV-Infected Adults

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2016-12-13
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The study is designed as a cross-sectional, single time point study for opportunistic oral cancer screening of HIV-infected and non- HIV adults 21 years or older in an urban hospital. All participants will undergo screening for oral cancer and oral potentially malignant disorders (OPMD) by visual...

Cost-effectiveness of Xpert MTB/RIF for Diagnosing Pulmonary Tuberculosis in HIV-positive Patients

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2016-12-01
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This is a prospective cross-sectional study which will be conducted at BJGMC in Pune, India. The aim of this study is to see whether Xpert MTB/RIF is useful for early detection of pulmonary tuberculosis, and therefore cost-effective, as compared with sputum microscopy and the gold standard tests...

The Evaluation of Clinical Profile and Mortality of Children Admitted with Tuberculosis in Pediatric Intensive-Care Unit at Sassoon General Hospitals, Pune

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2016-10-27
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Tuberculosis (TB) is one of the most common causes of infection-related death globally. TB was declared global public health emergency in 1993 by World HealthOrganization (WHO). Mortality due to TB is increasing due to emergence of multidrug resistant (MDR) strains and HIV-TB co-infection,...

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Antimicrobial susceptibility of Neisseria gonorrhoeae isolates in Baltimore, Maryland – 2016: The importance of sentinel surveillance in the era of multi-drug resistant gonorrhea

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2018-08-17
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Antibiotics
The increasing rates of gonorrhea infections and the global emergence and spread of multi-drug-resistant Neisseria gonorrhoeae (NG) threaten the successful management of gonorrhea. In the era of nucleic acid amplification tests (NAATs), surveillance projects are urgently needed to monitor...

Identifying solutions to improve the sexually transmitted infections testing experience for youth through participatory ideation

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2018-08-15
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AIDS Patient Care and STDs
Sexually transmitted infection (STI) services, including screening, treatment, and counseling among youth, remain suboptimal. In the midst of increasing incidence of bacterial STIs, alarming STI disparities, and persistently low testing rates among youth, solution-focused and action-oriented...

Challenges of TB and co-treatment: updates and insights

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2018-08-04
Publication: 
Current Opinion in HIV and AIDS
PURPOSE OF REVIEW: In the past few years, tuberculosis (TB) has overtaken HIV as the infectious disease with the highest global mortality. Successful management of this syndemic will require improved diagnostic tests, shorter preventive therapies, and more effective treatments, particularly in...

Tuberculin skin test and QuantiFERON-Gold In Tube assay for diagnosis of latent TB infection among household contacts of pulmonary TB patients in high TB burden setting

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2018-08-01
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PLoS One
World Health Organization (WHO) recommends systematic screening of high-risk populations, including household contacts (HHCs) of adult pulmonary tuberculosis (TB) patients, as a key strategy for elimination of TB. QuantiFERON-TB Gold In-Tube (QFT-GIT) assay and tuberculin skin test (TST) are two commonly used tools for the detection of latent tuberculosis infection (LTBI) but may yield differential results, affecting eligibility for TB preventive therapy.

Using mHealth to improve tuberculosis case identification and treatment initiation in South Africa: Results from a pilot study

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2018-07-03
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PLoS One
BACKGROUND: Tuberculosis (TB) incidence in South Africa is among the highest globally. Initial loss to follow-up (ILFU), defined as not starting on TB treatment within 28 days of testing positive, is undermining control efforts. We assessed the feasibility, acceptability, and potential of a mHealth...

Trends in HbA1c levels and implications for diabetes screening in tuberculosis cases undergoing treatment in India

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2018-07-01
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International Journal of Tuberculosis and Lung Disease
SETTING: The optimal timing of screening for diabetes mellitus (DM) among tuberculosis (TB) cases is unclear due to the possibility of stress hyperglycemia. DESIGN: We evaluated adult (18 years) pulmonary TB cases at treatment initiation as well as at 3 months, 6 months and 12 months. DM was...

Internal medicine residents' knowledge and practice of pulmonary tuberculosis diagnosis

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2018-06-27
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Open Forum Infectious Diseases
BACKGROUND: Internal medicine physicians are often the first providers to encounter patients with a new diagnosis of tuberculosis. Given the public health risks of missed tuberculosis cases, assessing internal medicine residents' ability to diagnose tuberculosis is important. METHODS: Internal...

Loss to follow‐up and mortality among HIV‐infected adolescents receiving antiretroviral therapy in Pune, India

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2018-06-25
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HIV Medicine
Over 6 years, one-third of HIV+ adolescents in this study discontinued medical treatment, indicating a critical need for retention counselling and closer clinical monitoring.

Effect of baseline micronutrient and inflammation status on CD4 recovery post-cART initiation in the multinational PEARLS trial

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2018-05-29
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Clinical Nutrition
Nutritional deficiency and inflammation may impact CD4+ T cell recovery during combination antiretroviral therapy (cART), particularly in resource-limited settings where malnutrition is prevalent. The aim of this study was to investigate the relationship of micronutrient and inflammation biomarkers to CD4 recovery after cART initiation.

Sources of household air pollution and their association with fine particulate matter in low-income urban homes in India

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2018-05-23
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Journal of Exposure Science and Environmental Epidemiology
INTRODUCTION: Household air pollution (HAP) is poorly characterized in low-income urban Indian communities. MATERIALS AND METHODS: A questionnaire assessing sources of HAP and 24 h household concentrations of particulate matter less than 2.5 microns in diameter (PM 2.5 ) were collected in a sample...

The global neurological burden of tuberculosis

Post Date: 
2018-05-18
Publication: 
Seminars in Neurology
Central nervous system (CNS) involvement of tuberculosis (TB) is the most severe manifestation of TB and accounts for approximately 5 to 10% of all extrapulmonary TB (EPTB) cases and approximately 1% of all TB cases. TB meningitis (TBM) is the most common form of CNS TB, though other forms occur,...

Group mentorship model to enhance the efficiency and productivity of PhD research training in Sub-Saharan Africa

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2018-05-04
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Annals of Global Health
Annals of Global Health : Systems capacity building approach to PhD training allowed strong outputs at lower cost and with relatively few additional mentors to train independent scientists able to conduct original research and mentor others.

Addressing knowledge gaps and prevention for tuberculosis-infected Indian adults: a vital part of elimination

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2018-05-02
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BMC Infectious Diseases
BMC Infectious Diseases : Our survey among TB patients' household contacts with evidence of recent exposure found that knowledge is poor and families are confused about disease transmission.

Hepatotoxicity during isoniazid preventive therapy and antiretroviral therapy in people living with HIV with severe immunosuppression: a secondary analysis of a multi-country open-label randomized controlled clinical trial

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2018-05-01
Publication: 
Journal of Acquired Immune Deficiency Syndromes
BACKGROUND: Hepatotoxicity associated with isoniazid preventive therapy (IPT) and antiretroviral therapy (ART) has not been well studied in severely immunosuppressed people with HIV. Our objective was to determine risk factors for hepatotoxicity in severely immunosuppressed individuals taking IPT...

MDR-TB in children: back to the basics

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2018-05-01
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The International Journal of Tuberculosis and Lung Disease
IJTLD: Summary of the Pediatric Multidrug-Resistant Tuberculosis Clinical Trials Landscape Meeting: a primer of current directions.

Advancing patient-centered care in tuberculosis management: A mixed-methods appraisal of video directly observed therapy

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2018-04-26
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Open Forum Infectious Diseases
BACKGROUND: Directly observed therapy (DOT) remains an integral component of treatment support and adherence monitoring in tuberculosis care. In-person DOT is resource intensive and often burdensome for patients. Video DOT (vDOT) has been proposed as an alternative to increase treatment flexibility...

Shorter treatment for minimal tuberculosis (TB) in children (SHINE): a study protocol for a randomised controlled trial

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2018-04-19
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Trials
Trials: Evidence for TB treatment in kids is largely based on adult studies. The SHINE study aims to fix this

Migration and risk of HIV acquisition in Rakai, Uganda: a population-based cohort study

Post Date: 
2018-04-15
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Lancet HIV
BACKGROUND: In sub-Saharan Africa, migrants typically have higher HIV prevalence than non-migrants; however, whether HIV acquisition typically precedes or follows migration is unknown. We aimed to investigate the risk of HIV after migration in Rakai District, Uganda. METHODS: In a prospective...

Prevention of HIV-1 transmission through breastfeeding:efficacy of safety of maternal antiretroviral therapy versus infant nevirapine prophylaxis for duration of breastfeeding in HIV-1-infected women with high CD4 cell count (IMPAACT PROMISE)

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2018-04-01
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Journal of Acquired Immune Deficiency Syndromes
BACKGROUND: No randomized trial has directly compared the efficacy of prolonged infant antiretroviral prophylaxis versus maternal antiretroviral therapy (mART) for prevention of mother-to-child transmission throughout the breastfeeding period. SETTING: Fourteen sites in Sub-Saharan Africa and India...

HIV viral suppression and geospatial patterns of HIV antiretroviral therapy treatment facility use in Rakai, Uganda

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2018-03-27
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AIDS
OBJECTIVE: To assess geospatial patterns of HIV antiretroviral therapy (ART) treatment facility use and whether they were impacted by viral load suppression. METHODS: We extracted data on the location and type of care services utilized by HIV-positive persons accessing ART between February 2015 and...

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A Study to Compare Efficacy of Oral High Dose Rifampicin with Standard Dose Rifampicin in Tuberculous Meningitis

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2017-10-13
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Basavaraj A , Avhad A, Kadam D. A Study to Compare Efficacy of Oral High Dose Rifampicin with Standard Dose Rifampicin in Tuberculous Meningitis. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico. October 13, 2017.

Prevalence of Vitamin D Deficiency among Indian Children with Tuberculosis and Age- and Sex-matched Controls

Post Date: 
2017-10-13
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Kinikar A , Chandanwale A, Dixit S, Jubilus J, Jain S, Bharadwaj R, Mave V, Gupte N, DeLuca A, Gupta A, Bollinger RC. Prevalence of Vitamin D Deficiency among Indian Children with Tuberculosis and Age- and Sex-matched Controls. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico...

Lack of TB Knowledge Among TST-Positive Household Contacts of Pulmonary Cases: A Missed Opportunity

Post Date: 
2017-10-13
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DeLuca A , Dhumal G, Paradkar M, Suryavanshi N, Mave V, Kohli R, Shivakumar SVBY, Gupta A. Lack of TB Knowledge Among TST-Positive Household Contacts of Pulmonary Cases: A Missed Opportunity. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico.

Biological Differences in Tuberculosis Diagnosis and Disease in Women

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2017-10-12
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Mathad J. Biological Differences in Tuberculosis Diagnosis and Disease in Women. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico.

Symposium: From Bench to Bassinet: Scientific Innovations: The Fight against Maternal-Infant TB

Post Date: 
2017-10-12
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Gupta A. Symposium: From Bench to Bassinet: Scientific Innovations: The Fight against Maternal-Infant TB. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico.

Barriers to Contact Screening and Isoniazid Preventive Therapy among Pediatric Contacts of Adults with Smear-positive Tuberculosis

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2017-10-12
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Belgaumkar V , Chandanwale A, Valvi C, Khadse S, Jain D, Dhumal G, Bollinger RC, Deluca A. Barriers to Contact Screening and Isoniazid Preventive Therapy among Pediatric Contacts of Adults with Smear-positive Tuberculosis. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico.

Drug Susceptibility of Rifampin-resistant Tuberculosis using Whole Genome Sequencing to Identify Genes of Interest in Pune, India

Post Date: 
2017-10-12
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Tornheim JA , Madugundu AK, Pradhan N, Bharadwaj R, Mave V, Golub J, Pandey A, Gupta A. Drug Susceptibility of Rifampin-resistant Tuberculosis using Whole Genome Sequencing to Identify Genes of Interest in Pune, India. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico.

Linezolid Experience among MDRTB Patients in Mumbai

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2017-09-13
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Tornheim J, Ganatra S, Deluca A, Banka R, Rodrigues C, Gupta A, Udwadia Z. Poster Presentation. Linezolid Experience among MDRTB Patients in Mumbai. ERS International Congress. European Respiratory Society. Milan, Italy.

Trends in Glycated Hemoglobin Levels and Implications for Diabetes Screening among Pulmonary Tuberculosis Cases Undergoing Treatment in India

Post Date: 
2017-09-13
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Gupte AN , Mave V, Meshram S, Lokhande R, Kadam D, Dharmshale S, Bharadwaj R, Kagal A, Pradhan N, Deshmukh S, Atre S, Sahasrabudhe T, Barthwal M, Meshram S, Kakrani A, Kulkarni V, Raskar S, Suryavanshi S, Shivakoti R, Chon S, Selvin E, Gupte N, Gupta A, Golub JE. Trends in Glycated Hemoglobin...

High Burden of Diabetes and Prediabetes among Adult Household Contacts of India

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2017-09-13
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Shivakumar SVBY , Chandrasekaran P, Kumar AJMV, Paradkar M, Dhanasekaran K, Suryavanshi N, Thomas B, Kohli R, Thiruvengadam K, Kulkarni V, Hannah LE, Sivaramakrishnan GN, Pradhan N, Dolla C, Gupte A, Ramachandran G, DeLuca A, Meshram S, Bhardawaj R, Bollinger RC, Golub J, Selvaraj K, Gupte N,...

Gene Expression Profiles of Pediatric Tuberculosis Patients and Exposed Controls from India

Post Date: 
2017-09-13
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Tornheim JA , Paradkar M, Madugundu A, Gupte N, Kulkarni V, Sreenivasamurthy S, Raja R, Pradhan N, Shivakumar SVBY, Valvi C, Kohli R, Chandrasekaran P, Mave V, Pandey A, Gupta A. Gene Expression Profiles of Pediatric Tuberculosis Patients and Exposed Controls from India. RePORT International...

Hepatotoxicity in HIV+ Postpartum Women Initiating Efavirenz-Containing Regimens

Post Date: 
2017-07-26
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Bhattacharya D , Gupta A, Tierney C, Huang S, Peters M, Chipato T, Martinson F, Dula D, George K, Chaktoura N, Klingman K, Gnanashanmugam D, Currier J, Fowler MG. Hepatotoxicity in HIV+ Postpartum Women Initiating Efavirenz-Containing Regimens. IAS 2017. International AIDS Society. Paris, France...

Hepatotoxicity in HIV+ Postpartum Women Initiating Efavirenz-Containing Regimens in PROMISE P1077

Post Date: 
2017-05-31
Amita Gupta. Hepatotoxicity in HIV+ Postpartum Women Initiating Efavirenz-Containing Regimens in PROMISE P1077. 2017 IMPAACT Annual Meeting. Washington, DC. 2017

A5300B/IMPAACT 2003B – PHOENix MDR TB: Protecting Households on Exposure to Newly Diagnosed Index Multidrug-Resistant TB Patients

Post Date: 
2017-05-30
Gupta, A. A5300B/IMPAACT 2003B – PHOENix MDR TB: Protecting Households on Exposure to Newly Diagnosed Index Multidrug-Resistant TB Patients. 2017 IMPAACT Annual Meeting. Washington, DC.

A5300/I2003/PHOENIx Trial Update

Post Date: 
2017-05-30
Gupta, A. A5300/I2003/PHOENIx Trial Update. 2017 IMPAACT Annual Meeting. Washington, DC. 2017.

IMPAACT 2001: Trial of the Pharmacokinetics, Tolerability, and Safety of Once-Weekly Rifapentine and Isoniazid in HIV-infected and HIV-1-uninfected Pregnant and Postpartum Women with Latent Tuberculosis Infection

Post Date: 
2017-05-30
Jyoti Mathad. IMPAACT 2001: Trial of the Pharmacokinetics, Tolerability, and Safety of Once-Weekly Rifapentine and Isoniazid in HIV-infected and HIV-1-uninfected Pregnant and Postpartum Women with Latent Tuberculosis Infection. 2017 IMPAACT Annual Meeting. Washington, DC. 2017.

CTRIUMPh Pediatric Biomarker Substudy

Post Date: 
2017-05-30
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Tornheim J . Paradkar M. CTRIUMPh Pediatric Biomarker Substudy. 2017 IMPAACT Annual Meeting. Washington, DC. 2017.

A5300/I2003/PHOENIx Preparatory Study of MDR TB Cases and Their Household Contacts: Operational Feasibility to Inform PHOENIx Trial

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2017-05-29
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Gupta, A. A5300/I2003/PHOENIx Preparatory Study of MDR TB Cases and Their Household Contacts: Operational Feasibility to Inform PHOENIx Trial. 2017 IMPAACT Annual Meeting. Washington, DC. 2017.

How Americans Benefit from Global Health Research

Post Date: 
2017-05-25
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Bollinger, R. How Americans Benefit from Global Health Research. The Fogarty International Center: How Americans Benefit from Global Health Research Webinar, Research!America. Washington, DC.

Knowledge, Attitudes and Practices About Multidrug-Resistant Tuberculosis (MDR-TB) and Preventive Therapy Among Adult and Adolescent Household Contacts of MDR-TB Index Cases

Post Date: 
2017-05-22
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Suryavanshi N, Shah S, Murrill M , Gupta A. Knowledge, Attitudes and Practices About Multidrug-Resistant Tuberculosis (MDR-TB) and Preventive Therapy Among Adult and Adolescent Household Contacts of MDR-TB Index Cases. American Thoracic Society 2017 International Conference. Washington, DC. 2017.

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CCGHE Joins 12-Country UNITAID Effort to Control TB

Post Date: 
2017-11-08
Shorter course to prevent progression of latent TB to active disease is the aim of the effort.

Efficacy maintained in HIV regimen switch

Post Date: 
2017-10-10
Source: 
MedPage Today
. . . "We still do have a lot of people on protease inhibitors in this country," Chida told MedPage Today. "Data to prove the safety and sustain viral load effect is important" to support decisions about switching. . .

CCGHE at the Union 2017

Post Date: 
2017-10-05
The 2017 Union Conference was in Guadalajaro, Mexico, October 11-14, and Indo-JHU research was well represented.

Tornheim Promoted to Assistant Professor

Post Date: 
2017-08-31
His research explores whether 2 MDR-TB drug susceptibility tests using WGS & MIC can yield options for individualized treament.

Reduced Level of Disease Possible in India by the Centennial

Post Date: 
2017-08-22
Source: 
India Abroad
India ranks highest in global disease burden. Dr. Amita Gupta weighs in on how to reverse that.

Indo-Hopkins Partnership Seeks Causes of Sepsis in the NICU

Post Date: 
2017-08-10
Sepsis among newborns in the neonatal intensive care unit (NICU) is a big problem in India, and a complex one to untangle.

How can we encourage female leaders in global health?

Post Date: 
2017-08-09
Source: 
Global Health Matters
Fogarty Director Dr. Roger Glass asks why so few women are leading global health centers at med schools or filling other leadership roles.

Sick and afraid, some immigrants forgo medical care

Post Date: 
2017-06-26
Source: 
The New York Times
Dr. Kathleen Page in the New York Times: US government deportation crackdown is affecting healthcare access among undocumented immigrants.

Company tests mobile health for tuberculosis treatment

Post Date: 
2017-05-23
Source: 
NIH: News and Events
Preliminary data show 93% treatment adherence using video observation, with savings of more than $1,000 per TB patient over 6 months

Fogarty International Center, a linchpin of global health research

Post Date: 
2017-05-17
Source: 
JAMA
Bob Bollinger weighs in on NIH’s Fogarty Program & the strategic benefits the program offers for US disease surveillance.

CCGHE at ATS 2017

Post Date: 
2017-05-08
Abstract presentations from the American Thoracic Society International Conference in Washington, DC

Health on the Go: Mobile Clinic Delivers TB Services at Point of Need

Post Date: 
2017-03-24
Thanks to Raj and Bharti Shah, CTIS, & the NB Shah Charitable Trust, we are able to reach more people in Maharashtra who need care

CROI 2017 Highlighted ACTG Network Presentations

Post Date: 
2017-02-28
Source: 
ACTG Newsletter
A5274: Impact of INH adherence on TB incidence and mortality by week 96 in REMEMBER Trial Amita Gupta, MD, MHS, Baltimore-Washington-India Clinical Trials Unit, co-PI and Investigator, Johns Hopkins University Clinical Research Site The A5274/REMEMBER trial team previously reported that among those...

2017 Directors' Statement

Post Date: 
2017-01-31
A New Decade of Global Health Impact The CCGHE recently marked its 10-year anniversary, and it’s an occasion that affords an opportunity to reflect on the progress we’ve made so far, and envision what lies ahead. We are encouraged by the changes we’ve seen in health outcomes for people living with...

Global Impact Report

Post Date: 
2017-01-31
Learn about CCGHE's work to improve infectious disease prevention & treatment around the world.

emocha and miDiagnostics collaborate to achieve more comprehensive mobile testing

Post Date: 
2016-12-12
Source: 
iMedicalApps
Baltimore-based tech startup emocha is collaborating with miDIAGNOSTICS in order to combine hardware and software to augment current medical tests for patients and health care providers. Emocha is a Johns Hopkins startup spinout and the end goal is to utilize each company’s strengths to bring test...

World AIDS Day 2016 at BJGMC

Post Date: 
2016-12-06
Read more about 2016 World AIDS Day activities at the BJGMC Clinical Site in Pune, India.

CCGHE at ID Week 2016

Post Date: 
2016-10-11
OCTOBER 27 TB Infection Prevalence, Incidence and Risk Factors among Child and Adult Household Contacts of Adult TB Cases in India Shivakumar SVBY, Chandrasekaran P, Thiruvengadam K, Gupte N, Mave V, Hannah LE, Kulkarni V, Gupte A, Deluca A, Gomathy NS, Sathyamurthi P, Paradkar M, Kohli R, Meshram...

Imec’s miDiagnostics joint venture does blood tests from blood-drop

Post Date: 
2016-08-09
Source: 
Electronics Weekly
miDiagnostics, the joint venture between Imec and Johns Hopkins University, aims to develop IC-based diagnostic tests which use drops of blood to detect cells, proteins, nucleic acids, and/or small molecules.

Emocha brings TB adherence tech to California as part of national expansion

Post Date: 
2016-08-02
Source: 
MedCity News
Emocha, a digital health startup seeking to create more flexibility for tuberculosis patients to meet the requirements for Directly Observed Therapy, or DOT, has added a new set of customers in California as part of a national expansion.

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