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Study shows success with TB therapy observation conducted via video instead of via in-person clinic visits.

Children in Maharashtra India

Trials: Evidence for TB treatment in kids is largely based on adult studies. The SHINE study aims to fix this

Clinical Research

Leadership
Dr. Amita Gupta of Johns Hopkins is Principal Investigator for the Indo-JHU Clinical Research Partnership based out of CCGHE. Research is directed locally in India out of the BJGMC-JHU Clinical Research Site by Dr. Vidya Mave, a Hopkins faculty member who lives in Pune. Dr. Nikhil Gupte is the Lead Biostatistician and Deputy Director and Dr. Nishi Suryavanshi is Clinical Site Coordinator and Deputy Director. Research is conducted in collaboration with the following institutions:
 
 

Diagnosis of Tuberculosis Infection and Th1 Immune Response in Pregnant Women in India

Post Date: 
2014-09-01
Country: 
Tuberculosis (TB) disease is a major cause of mortality among Indian women of reproductive age; approximately 20-50% of women in India are latently infected with Mycobacterium tuberculosis (MTB). Due to immune changes of pregnancy, women are particularly at risk of reactivation and progression to...

PreventionRx Study: Home-based Counseling and Testing in Uganda

Post Date: 
2014-08-27
Country: 
A ‘platform’ for evaluating combination HIV prevention & care-HIV counseling & testing is essential to optimize HIV services. In collaboration with the University of Washington and the Integrated Community Based Initiatives (ICOBI) NGO in Uganda, CCGHE has adapted the emocha ® platform to...

Evaluating Demand Generation (Stylish Man) for HIV/Family Planning Services, Rakai, Uganda

Post Date: 
2014-08-01
Country: 
Dr. Larry Chang is co-investigator of this effort to test a novel approach to promoting HIV services in Rakai, Uganda. The Stylish Man Program, attempts to “demedicalize” HIV prevention and care in a public health campaign designed to normalize HIV care as part of self care for African men. The...

A5279: Phase III Clinical Trial of Ultra-Short-Course Rifapentine/Isoniazid for the Prevention of Active Tuberculosis in HIV-infected Individuals with Latent Tuberculosis Infection

Post Date: 
2014-06-30
Country: 
Dr. Amita Gupta is Protocol Co-Vice Chair for this multinational clinical trial being conducted in Botswana, Brazil, Haiti, Kenya, Malawi, Peru, Puerto Rico, South Africa, Tanzania, Thailand, Uganda, United States, Zambia, Zimbabwe, and India by the Baltimore-Washington-India Clinical Trials Unit,...

Evaluation of Longitudinal Blood Culture Isolates from BJ Medical College in Pune, India

Post Date: 
2014-06-16
Country: 
Antibiotic resistance is a serious global problem and is caused by multiple factors which have led to difficulty in the management of life-threatening, multi-drug resistant (MDR) bacterial bloodstream infections. The knowledge of antibiotic resistance patterns and availability of appropriate...

Optimizing Treatment to Improve TBM Outcomes in Children

Post Date: 
2014-05-01
Country: 
This study is being conducted in India and Malawi. Primary Objectives To characterize the pharmacokinetics (PK) (plasma and cerebrospinal fluid (CSF)) of rifampicin given at model-derived optimal daily doses and levofloxacin in children ages 6 months to 12 years of age with TBM To assess the...

P1078: A Phase IV Randomized Double-Blind Placebo-Controlled Trial to Evaluate the Safety of Immediate (Antepartum-Initiated) Versus Deferred (Postpartum-Initiated) Isoniazid Preventive Therapy Among HIV-Infected Women in High TB Incidence Settings

Post Date: 
2014-04-01
Country: 
Dr. Amita Gupta is Protocol Chair for this multinational clinical trial being conducted in Botswana, Haiti, South Africa, Tanzania, Thailand, Uganda, and Zimbabwe, and in India by the Baltimore-Washington-India Clinical Trials Unit, of which CCGHE is a member. Background Tuberculosis (TB) is the...

Pulmonary and Functional Status of Patients with Pulmonary Mycobacterium Tuberculosis Post-treatment in Lima, Peru

Post Date: 
2014-01-01
Country: 
To conduct a longitudinal study evaluating the hypothesis that pulmonary function and functional status (functional capacity and quality of life) is reduced among individuals previously treated for pulmonary tuberculosis compared to those without a history of tuberculosis.

RePORT: C-TRIUMPH: Cohort for Tuberculosis Research by the Indo-US Medical Partnership

Post Date: 
2013-09-28
Country: 
Collaboratively funded by the US NIH, India’s Department of Biotechnology [DBT], and Indian Council of Medical Research, the Cohort for TB Research by the Indo-US Medical Partnership (C-TRIUMPH) is an Indo-US research consortium that is part of RePORT India, a countrywide consortium for TB research...

RePORT: C-TRIUMPH: Substudy on Assessing the Association of Indoor Air Pollution with Tuberculosis in Adult Women and Children under 5 Years of Age

Post Date: 
2013-09-15
Country: 
Addressing social and environmental risk factors contributing to TB disease is becoming increasingly important for national TB programs. We are leveraging the pediatric participants in 1,100 homes participating in the C-TRIUMPH study, enhancing data collection regarding household and individual...

Community Home Based India Prevention of Mother to Child Transmission of HIV (COMBIND)

Post Date: 
2013-09-02
Country: 
CCGHE is assessing whether equipping Community Health Workers with mobile health technology and involving them in technology training and personal empowerment seminars can help prevent mother-to-child transmission of HIV. CHWs who care for HIV + pregnant and nursing women are using the emocha...

Impact of Diabetes on TB Treatment Outcomes

Post Date: 
2013-02-01
Country: 
CCGHE, the JHU Center for TB Research and BJGMC have been awarded a $2.5 million dollar NIH grant (2013-2018) to conduct a study to evaluate treatment outcomes among Indian patients with both diabetes mellitus and active TB. This study is assessing the prevalence of impaired glucose or frank...

Acute Febrile Illness and Antimicrobial Resistance Patterns in Pune, India

Post Date: 
2013-01-10
Country: 
Evaluate etiology of acute fever and bacterial drug resistance patterns among adults and children in India.

Feasibility and Acceptability of Smartphone-Based Ecological Momentary Assessment of Alcohol Use Among African American Men Who Have Sex With Men in Baltimore

Post Date: 
2013-01-01
Country: 
This study provides evidence to support the feasibility and acceptability of using Ecological Momentary Assessment (EMA ) methods for collecting data on alcohol use among African American men who have sex with men living in urban settings. These data provide the basis for future studies of EMA-...

ONCOGRID: An mHealth Approach to Prevention and Early Diagnosis of Oral Cancer in Rural South India

Post Date: 
2012-11-01
Country: 
The Indian sub-continent is burdened with 80% of the world’s patients with oral cancer, and delay in oral cancer diagnosis is one of the major problems that leads to poor treatment outcomes (V. Shanta, R. Swaminathan, R. Rama. Cancer Control 2013). Current screening and treatment programs are not...

Project Connect Baltimore: Connecting Young Males to Sexual/Reproductive Healthcare

Post Date: 
2012-10-01
Country: 
To design, implement and evaluate a male-friendly and culturally appropriate guide for increasing access to and use of human immunodeficiency virus (HIV)/sexually transmitted disease (STD) testing and sexual/reproductive healthcare (SRHC) among African American and Latino males.

Diagnosis of Active Tuberculosis in HIV-infected and Uninfected Young Children in India

Post Date: 
2012-07-24
Country: 
Tuberculosis (TB) is the most common cause of morbidity/mortality in HIV-infected individuals in India. India has the world's highest burden of HIV and TB, and since children acquire HIV/TB from their caregivers, active TB is highly prevalent (14-67.5%) among HIV-infected young children in India...

A5288: MULTIOCTAVE, Management Using the Latest Technologies in Resource-limited Settings to Optimize Combination Therapy After Viral Failure

Post Date: 
2012-07-16
The study is being done to test a strategy of using a resistance test to choose anti-HIV drugs. Resistance tests look at the HIV in your blood to see which drugs might work best to lower your HIV infection. see how well combinations of new anti-HIV drugs work to lower HIV infection see if taking...

RePORT India

Post Date: 
2012-06-30
Country: 
RePORT India is a joint venture between the Indian and US governments. The Indo-US Vaccine Action Program, a collaboration between the Indian Department of Biotechnology (DBT), the Indian Council of Medical Research (ICMR), and the US NIH, is co-funding six teams of India- and US-based...

Analysis of Data Collected from the Evaluation of Community-Based Education, Research and Service (COBERS)

Post Date: 
2012-06-12
Country: 
Makerere University College of Health Sciences (MakCHS), the Medical Schools at Gulu University (GU), Mbarara University of Science and Technology (MUST), Kampala International University (KIU) and Busitema University (BU) came together with Johns Hopkins University (JHU) in 2010 to form Medical...

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Heterogeneity of the HIV epidemic in agrarian, trading, and fishing communities in Rakai, Uganda: an observational epidemiological study

Post Date: 
2016-08-15
Publication: 
The Lancet HIV
Country: 
Background : Understanding the extent to which HIV burden differs across communities and the drivers of local disparities is crucial for an effective and targeted HIV response. We assessed community-level variations in HIV prevalence, risk factors, and treatment and prevention service uptake in...

Community-based interventions to improve and sustain antiretroviral therapy adherence, retention in HIV care and clinical outcomes in low- and middle-income countries for achieving the UNAIDS 90-90-90 targets

Post Date: 
2016-07-30
Publication: 
Current HIV/AIDS Reports
Country: 
Little is known about the effect of community versus health facility-based interventions to improve and sustain antiretroviral therapy (ART) adherence, virologic suppression, and retention in care among HIV-infected individuals in low- and middle-income countries (LMICs). We systematically searched...

Continued elevation of interleukin-18 and interferon-γ after initiation of antiretroviral therapy and clinical failure in a diverse multicountry human immunodeficiency virus cohort

Post Date: 
2016-07-27
Publication: 
Open Forum Infectious Diseases
Country: 
Background: We assessed immune activation after antiretroviral therapy (ART) initiation to understand clinical failure in diverse settings. Methods: We performed a case-control study in ACTG Prospective Evaluation of Antiretrovirals in Resource-Limited Settings (PEARLS). Cases were defined as...

Association of medical male circumcision and antiretroviral therapy scale-up with community HIV incidence in Rakai, Uganda

Post Date: 
2016-07-12
Publication: 
JAMA
Country: 
IMPORTANCE: Medical male circumcision (MMC) and antiretroviral therapy (ART) are proven HIV prevention interventions, but there are limited data on the population-level effect of scale-up of these interventions in sub-Saharan Africa. Such evaluation is important for planning and resource allocation...

Epidemiological impact of achieving UNAIDS 90-90-90 targets for HIV care in India: a modelling study

Post Date: 
2016-07-07
Publication: 
BMJ Open
Country: 
Objective: Recent UNAIDS ‘90-90-90’ targets propose that to end the HIV epidemic by 2030, 90% of persons living with HIV (PLWH) worldwide should know their diagnosis, 90% of diagnosed PLWH should be on antiretroviral therapy (ART) and 90% of PLWH on ART should be virally suppressed by 2020. We...

Inflammation and change in body weight with antiretroviral therapy initiation in a multinational cohort of HIV-infected adults

Post Date: 
2016-07-01
Publication: 
Journal of Infectious Diseases
Country: 
Background: Both wasting and obesity are associated with inflammation, but the extent to which body weight changes influence inflammation during human immunodeficiency virus infection is unknown. Methods: Among a random virologically suppressed participants of the Prospective Evaluation of...

Defining clinical excellence in adult infectious disease practice

Post Date: 
2016-06-16
Publication: 
Open Forum Infectious Diseases
Country: 
Clinical excellence should be recognized, particularly in the current climate that appropriately prioritizes relationship-centered care. In order to develop a recognition model, a definition of clinical excellence must be created and agreed upon. A paradigm recently suggested by C. Christmas...

Quantitative IFN-y,IL-2 response and latent tuberculosis test discordance in HIV-infected pregnant women

Post Date: 
2016-06-15
Publication: 
American Journal of Respiratory and Critical Care Medicine
Country: 
Rationale: Pregnant women with latent tuberculosis infection (LTBI) are at high risk for development of TB, especially if infected with HIV. Objectives: To assess the performance of LTBI tests in pregnant and postpartum women infected with HIV, investigate the immunology behind discordance in...

Isoniazid hair concentrations in children with tuberculosis: a proof of concept study

Post Date: 
2016-06-01
Publication: 
International Journal of Tuberculosis and Lung Disease
Country: 
Assessing treatment adherence and quantifying exposure to anti-tuberculosis drugs among children is challenging. We undertook a 'proof of concept' study to assess the drug concentrations of isoniazid (INH) in hair as a therapeutic drug monitoring tool. Children aged <12 years initiated on a...

The availability of emergency obstetric care in the context of the JSY cash transfer programme in Madhya Pradesh, India

Post Date: 
2016-05-18
Publication: 
BMC Pregnancy and Childbirth
Country: 
Abstract Background: Since 2005, India has implemented a national cash transfer programme, the Janani Suraksha Yojana (JSY), which provides women a cash transfer upon giving birth in an existing public facility. This has resulted in a steep rise in facility births across the country. The early...

Public health clinic-based hepatitis C testing and linkage to care in Baltimore

Post Date: 
2016-05-15
Publication: 
Journal of Viral Hepatitis
Country: 
Testing and linkage to care are important determinants of hepatitis C virus (HCV) treatment effectiveness. Public health clinics serve populations at high risk of HCV. We investigated their potential to serve as sites for HCV testing, initiation of and linkage to HCV care. Cross-sectional study of...

Applying ethical principles to international community-based research; a case study from the Consortium to Respond Effectively to the AIDS/TB Epidemic

Post Date: 
2016-05-15
This paper describes how one set of HIV-TB prevention research studies put procedures in place to be responsive to these foundational ethical principles when interacting with communities in large population-based, global public health research.

Management and control of multidrug-resistant tuberculosis (MDR-TB): addressing policy needs for India

Post Date: 
2016-05-06
Publication: 
Journal of Public Health Policy
Country: 
Multidrug-resistant tuberculosis (MDR-TB) challenges TB control efforts because of delays in diagnosis plus its long-term treatment which has toxic effects. Of TB high-incidence countries, India carries the highest burden of MDR-TB cases. We describe policy issues in India concerning MDR-TB...

High proportion of extrapulmonary tuberculosis in a low prevalence setting: a retrospective cohort study

Post Date: 
2016-04-29
Publication: 
Public Health
Country: 
Objectives: The proportion of extrapulmonary tuberculosis (EPTB) cases in the United States (US) has been rising due to a slower rate of decline in EPTB compared to pulmonary tuberculosis (PTB). The purpose of this study was to characterise the clinical and treatment differences between EPTB and...

Inflammation and change in body weight with antiretroviral therapy initiation in a multinational cohort of HIV-infected adults

Post Date: 
2016-04-01
Publication: 
The Journal of Infectious Diseases
Background: Both wasting and obesity are associated with inflammation, but the extent to which body weight changes influence inflammation during human immunodeficiency virus infection is unknown. Methods: Among a random virologically suppressed participants of the Prospective Evaluation of...

Persistently elevated C-reactive protein level in the first year of antiretroviral therapy, despite virologic suppression, is associated with HIV disease progression in resource-constrained settings

Post Date: 
2016-04-01
Publication: 
The Journal of Infectious Diseases
A case-cohort analysis of human immunodeficiency virus (HIV)-infected individuals receiving antiretroviral therapy (ART) was performed within a multicountry randomized trial (PEARLS) to assess the prevalence of persistently elevated C-reactive protein (CRP) levels, based on serial measurements of...

High tuberculosis risk among medical trainees, Pune, India

Post Date: 
2016-03-22
Publication: 
Emerging Infectious Diseases
Country: 
During 2012–2013, at a public hospital in Pune, India, 26 (3.9%) cases of tuberculosis were reported among 662 medical trainees, representing an estimated incidence of 3,279 cases/100,000 person-years. Three of these infections were isoniazid-resistant, 1 was multidrug-resistant, and 1 occurred in...

Empirical tuberculosis therapy versus isoniazid in adult outpatients with advanced HIV initiating antiretroviral therapy (REMEMBER): a multicountry open-label randomised controlled trial

Post Date: 
2016-03-19
Publication: 
The Lancet
Background: Mortality within the first 6 months after initiating antiretroviral therapy is common in resource-limited settings and is often due to tuberculosis in patients with advanced HIV disease. Isoniazid preventive therapy is recommended in HIV-positive adults, but subclinical tuberculosis can...

Ecological momentary assessment of illicit drug use compared to biological and self-reported methods

Post Date: 
2016-03-15
Publication: 
Journal of Medical Internet Research
Country: 
Background: The use of mHealth methods for capturing illicit drug use and associated behaviors have become more widely used in research settings, yet there is little research as to how valid these methods are compared to known measures of capturing and quantifying drug use. Objective: We examined...

Infectious Diseases (ID) Learning Unit: How rapidly to evaluate for active tuberculosis disease in low-prevalence settings

Post Date: 
2016-03-11
Publication: 
Open Forum Infectious Diseases
Country: 
With declining tuberculosis (TB) incidence in low-prevalence settings, many clinicians are likely unaware that the approach to diagnosing active TB is evolving with newer technologies. Rapid molecular assays are commercially available, and more are likely to enter the market in the coming years...

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The Impact of Health Seeking Behavior on Community-acquired Multi-drug Resistant Stool Colonization among Hospitalized Febrile Illness Patients in Pune, India

Post Date: 
2016-10-29
Presentation Location: 
New Orleans, LA
Country: 
Event & Convener: 
ID Week 2016
Poster Session: Antibiotic Stewardship: Outpatient and ED. Sachs J , Bharadwaj R, Khadse S, Kadam D, Kagal A, Shaikh N, Shingada K, Raichur P, Kanade S, Suryanvanshi N, Gupta A, Robinson M, Mave V.

Choosing an ID Fellowship

Post Date: 
2016-10-29
Presentation Location: 
New Orleans, LA
Event & Convener: 
ID Week 2016
Presenter, Symposium: Choosing a Career in Infectious Diseases

Impact of Drug Susceptibility Testing on Drug Choice in a Tuberculosis Cohort with High Rates of Drug Resistance from the Private Sector in Mumbai

Post Date: 
2016-10-27
Presentation Location: 
New Orleans, LA
Country: 
Event & Convener: 
ID Week 2016
Poster Abstract Session: Tuberculosis Treatment and Outcome. Udwadia ZF, Tornheim JA , Ganatra S, DeLuca A, Banka R, Gupta A

Etiology of Acute Febrile Illness among Hospitalized Adults and Children at a Public Tertiary-Care Center in Pune, India

Post Date: 
2016-10-27
Presentation Location: 
New Orleans, LA
Country: 
Event & Convener: 
ID Week 2016
Poster Abstract Session: Oh One World: Infections from Near and Far. Robinson M , Balasubramanian U, Raichur P, Kadam D, Khadse S, Marbaniang I, Kanade S, Sachs J, Basavaraj A, Bharadwaj R, Kinikar A, Kulkarni V, Kagal A, Gupta A, Mave V

Xpert® MTB/RIF Assay for Pulmonary Tuberculosis Diagnosis in Patients with Diabetes Mellitus

Post Date: 
2016-10-27
Presentation Location: 
Durban, South Africa
Event & Convener: 
47th Union World Conference on Lung Health. International Union for Tuberculosis and Lung Disease.
Poster Presentation. Mave V , Gupte N, Meshram S, Kagal A, Gupta A, Bharadwaj R, Pradhan N, Deshmukh S, Atre S, Golub J

TB Infection Prevalence, Incidence and Risk Factors among Child and Adult Household Contacts of Adult TB Cases in India

Post Date: 
2016-10-27
Presentation Location: 
New Orleans, LA
Country: 
Event & Convener: 
ID Week 2016
Poster presentation. Shivakumar SVBY , Chandrasekaran P, Thiruvengadam K, Gupte N, Mave V, Hannah LE, Kulkarni V, Gupte A, Deluca A, Gomathy NS, Sathyamurthi P, Paradkar M, Kohli R, Meshram S, Kagal A, Suryavanshi N, Ramachandran G, Thomas B, Dolla CK, Subramanyam B, Golub J, Swaminathan S, Gupta A.

Household Contact Tracing of Adult Pulmonary TB Patients in India: Prevalence of TB Disease and Infection

Post Date: 
2016-10-27
Presentation Location: 
New Orleans, LA
Country: 
Event & Convener: 
ID Week 2016
Poster Abstract Session: Tuberculosis Epidemiology and Diagnosis. Chandrasekaran P , Thiruvengadam K, Gupte N, Luck EH, Mave M, Gupte A, Gupta A, Swaminathan S

Host Factors Associated with Poor Respiratory Health-Related Quality of Life in Pulmonary Tuberculosis

Post Date: 
2016-10-27
Presentation Location: 
New Orleans, LA
Country: 
Event & Convener: 
ID Week 2016
Poster Abstract Session: Tuberculosis Treatment and Outcome. Gupte A , Meshram S, Selvaraju S, Gupte N, Shivakumar SVBY, Paradkar M, Kohli R, Theruvengadam K, Suryavanshi N, Chandrasekaran P, Mave V, Swaminathan S, Salvi S, Checkley, W, Golub J, Gupta A

A Case-control Study of Household Air Pollution and Tuberculosis in Women and Children in Pune, India

Post Date: 
2016-10-26
Presentation Location: 
Liverpool, England
Country: 
Event & Convener: 
46th Union World Conference on Lung Health. International Union for Tuberculosis and Lung Disease
Oral Presentation. Elf JL , Kinikar A, Khadse S, Mave V, Gupte N, Kulkarni V, Patekar S, Raichur P, Breysse PN, Gupta A, Golub JE.

TB and Diabetes in Pregnancy: Current Knowledge and Research Gaps

Post Date: 
2016-10-24
Presentation Location: 
Liverpool, England
Event & Convener: 
47th Union World Conference on Lung Health. International Union for Tuberculosis and Lung Disease.
Presentation. Workshop: Integrated Care and Research for Tuberculosis, Diabetes, and HIV/AIDS: Challenges, Strategies, and Clinical Solutions

Sub-Therapeutic Concentrations of Anti-Tuberculosis Drugs in Children when Treated According to Indian Dosing Recommendation

Post Date: 
2016-10-24
Presentation Location: 
Liverpool, England
Country: 
Event & Convener: 
9th Annual International Workshop on Clinical Pharmacology of Tuberculosis Drugs
Oral Presentation. Guiastrennec B , Ramachandran G, Karlsson MO, Kumar H, Bhavani PK, Gangadevi NP, Swaminathan S, Gupta A, Dooley KE, Savic RM.

Vancomycin-resistant Enterococcal Bacteraemia: Is Daptomycin as Effective as Linezolid?

Post Date: 
2016-10-04
Presentation Location: 
San Diego, CA
Event & Convener: 
Infectious Diseases Society of America. 2007 Annual Meeting.
Presentation.

Outreach Workers in the Prevention of Mother to Child Transmission of HIV (PMTCT) Programme in India: Challenges and Opportunities

Post Date: 
2016-07-21
Presentation Location: 
Durban, South Africa
Country: 
Event & Convener: 
21st Annual International AIDS Conference (AIDS 2016)
Abstract Presentation. Suryavanshi N , Mave V, Kadam A, Kanade S, Sivalenka S, Sampath K, Harve P, Gupta RS, Hegde A, McKenzie-White J, Gupte N, Gupta A, Bollinger RC, Shankar AV.

A Cluster-Randomized Trial to Promote Combination HIV Prevention Using M-health-Supported CHWs in a High-Prevalence Fishing Community: Design and Baseline Characteristics of the mLAKE Trial in Rakai, Uganda

Post Date: 
2016-07-21
Presentation Location: 
Durban, South Africa
Country: 
Event & Convener: 
21st International AIDS Conference. International AIDS Society.
Abstract Presentation. Chang L, Mbabali I, Kong X, Hutton H, Long A, Thomas A, Bugos E, Ssekasanvu J, Kennedy C, Amico R, Nalugoda F, Reynolds S, Quinn T, Serwadda D, Wawer M, Gray R, Nakigozi G.

Rapid Diagnosis, Linkage and Treatment Initiation of Patients with Drug-resistant Tuberculosis in South Africa: The miLINC Solution to Improve Access to Care

Post Date: 
2016-07-20
Presentation Location: 
Durban, South Africa
Country: 
Event & Convener: 
21st International AIDS Conference. International AIDS Society.
Poster Presentation. Farley JE , Seiguer S, Naicker M, McKenzie-White J, Greg C, Elmi M, Stevens W, Stewart-Isherwood L

High Risk for Loss to Follow-Up among Adolescents Living with HIV in Pune, India

Post Date: 
2016-07-19
Presentation Location: 
Durban, South Africa
Country: 
Event & Convener: 
21st International AIDS Conference. International AIDS Society.
Presentation. Nimkar S , Valvi C, Khadse S, Kadam D, Kinikar A, Marbaniang I, Rewari BB, Chandanwale A, Suryavanshi N, Patil S, Nevrekar N, Raichur P, Gupta A, Mave V

Host Factors Associated with Poor Respiratory Health-related Quality of Life in Pulmonary Tuberculosis

Post Date: 
2016-07-17
Presentation Location: 
Durban, South Africa
Event & Convener: 
21st Annual International AIDS Conference (AIDS 2016)
RePORT International Oral Abstract Presentation. Gupte A , Meshram S, Selvaraju S, Gupte N, Shivakumar SVBY, Paradkar M, Kohli R, Theruvengadam K, Suryavanshi N, Chandrasekaran P, Mave V, Swaminathan S, Salvi S, Checkley, W, Golub J, Gupta A

A5300/I2003: Feasibility of Identifying, Recruiting, and Characterizing Adult MDR TB Index Cases and their Adult and Child Household Contacts on Four Continents

Post Date: 
2016-07-17
Presentation Location: 
Durban, South Africa
Event & Convener: 
TB2016. International AIDS Society.
Poster Presentation. Swindells S , Kim S, Gupta A, Hesseling AC, Shah S, Johnson D, Harrington M, Suryavanshi N, Sanchez J, Dawson R, Naini L, Jones L, Hughes M, Churchyard G, for ACTG/IMPAACT

Prevalence of and Risk Factors for Diabetes mellitus among Pulmonary Tuberculosis Patients in Pune, India.

Post Date: 
2016-07-16
Presentation Location: 
Durban, South Africa
Country: 
Event & Convener: 
TB2016. International AIDS Society.
Poster presentation.

The Association of Household Air Pollution and Tuberculosis in Women and Children in Pune, India

Post Date: 
2016-06-21
Presentation Location: 
Baltimore, MD
Country: 
Event & Convener: 
2016 Annual Meeting. Johns Hopkins Center for Tuberculosis Research
Presentation

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Multidrug TB prophylaxis not needed in advanced HIV

Post Date: 
2016-03-18
Source: 
MedPage Today
Patients with advanced HIV infection initiating anti-retroviral therapy who were treated with isoniazid alone to prevent tuberculosis had similar survival rates as patients treated with a standard four-drug anti-tuberculosis regimen in a multi-national, randomized, controlled trial.

Proactively treating HIV patients at risk for tuberculosis with multi-drug TB regimens doesn't save more lives

Post Date: 
2016-03-18
Source: 
Infection Control Today
In what investigators say is a surprise finding, results of a new study appear to strongly affirm the effectiveness of prescribing the anti-tuberculosis drug isoniazid alone — in place of the standard four-drug regimen — to prevent TB and reduce death in

Common TB treatment in HIV: no added benefit?

Post Date: 
2016-03-18
Source: 
Pharmaceutical Processing Online
In a report on the REMEMBER (Reducing Early Mortality and Early Morbidity by Empiric Tuberculosis Treatment) study—a 10-nation, randomized clinical trial of adult outpatients—investigators concluded that there was no added benefit of using four drugs for TB over just using one drug, isoniazid, to...

4-drug tuberculosis treatment among HIV/AIDS patients does not save more lives

Post Date: 
2016-03-18
Source: 
MedIndia
There was no added benefit of using four drugs for tuberculosis over using just one drug, isoniazid, to save lives in people with advanced HIV/AIDS, revealed a report on the so-called REMEMBER (Reducing Early Mortality and Early Morbidity by Empiric Tuberculosis Treatment) study—a 10 nation,...

Common treatment of TB in advanced HIV patients doesn't save more lives

Post Date: 
2016-03-17
Source: 
Medical Xpress
In a report on the so-called REMEMBER (Reducing Early Mortality and Early Morbidity by Empiric Tuberculosis Treatment) study—a 10-nation, randomized clinical trial of adult outpatients—investigators concluded that there was no added benefit of using four drugs for TB over just using one drug,...

Proactively treating HIV patients at risk for tuberculosis with multidrug TB therapy doesn’t save more lives

Post Date: 
2016-03-17
In what investigators say is a surprise finding, results of a new study appear to strongly affirm the effectiveness of prescribing the anti-tuberculosis drug isoniazid alone — in place of the standard four-drug regimen — to prevent TB and reduce death in people with advanced HIV/AIDS infections...

CCGHE at CROI 2016

Post Date: 
2016-02-29
JOHNS HOPKINS CENTER FOR CLINICAL GLOBAL HEALTH EDUCATION AT CROI 2016 FEBRUARY 22-25 2016 | BOSTON, MASSACHUSETTS TUESDAY, FEBRUARY 23 Combination HIV Prevention and HIV Incidence in a Ugandan Hotspot Fishing Community. Poster Presentation. Session: HIV Testing and Prevention. Authors: Kagaayi J,...

Now, docs to get TB leave as cases mount

Post Date: 
2016-02-24
Source: 
Pune Mirror
Too many cases of tuberculosis (TB) among medical trainees and resident doctors in the state have prompted the medical education department to sanction medical leaves exclusively for the malady. This is the first time any state has taken such a step in India. Unusual working hours; close contact...

VIDEO: Amita Gupta, MD, MHS, reviews TB prevention in patients with HIV

Post Date: 
2016-02-24
Source: 
Infectious Disease News, via Healio
In this video with Healio.com, Amita Gupta, MD, MHS, associate professor medicine and international health and deputy director of the Center for Clinical Global Health Education at Johns Hopkins University School of Medicine, discusses research related to the prevention of tuberculosis in patients...

LEAP Program a Resource for Investigators of New Antiretrovirals

Post Date: 
2016-02-03
February 3, 2016—Baltimore, MD—The Johns Hopkins Center for Clinical Global Health Education, the Johns Hopkins Departments of Medicine and Pharmacology and Molecular Sciences, and the University of Liverpool launched a new website for an NIH-funded drug development resource called the Long-Acting/...

Up Close: Matthew Robinson

Post Date: 
2016-02-01
Looking for Causes of Fever in India “The most common reason Indians go to the doctor is for fever. The list of potential causes for fever in India and other low and middle income countries in tropical settings is extensive.” Matt Robinson, MD, is a Clinical Fellow whose research in India aims to...

Tuberculosis test may underreport in pregnant women with HIV

Post Date: 
2016-01-28
Source: 
Infectious Disease Advisor
Pregnancy may confound tuberculosis (TB) tests results in women with HIV, according to research published in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine .

Tuberculosis scare in HIV positive pregnant women: most widely-used tuberculosis test fails to diagnose illness

Post Date: 
2016-01-28
Source: 
International Business Times
The most commonly-used tuberculosis (TB) test, TST, has failed to detect TB in HIV positive pregnant women. A research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine has revealed that the TB test failed to accurately diagnose the...

Most commonly used TB test fails to accurately diagnose pregnant, HIV-positive women

Post Date: 
2016-01-25
Source: 
Infection Control Today
New research finds that the most commonly used test for tuberculosis fails to accurately diagnose TB in up to 50 percent of pregnant women who are HIV positive. The research published early online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine is...

BJGMC Clinical Research Site Observes World AIDS Day

Post Date: 
2015-12-14
Pune, India—To mark the struggle of those living with HIV and in commemoration of those who have lost their lives, the Clinical Research Site at Byramjee Jeejeebhoy Government Medical College (BJGMC CRS) participated in the National AIDS Trust’s World AIDS Day . Each year on December 1, events are...

CCGHE At The Union 2015

Post Date: 
2015-11-30
JOHNS HOPKINS CENTER FOR CLINICAL GLOBAL HEALTH EDUCATION AT THE UNION DECEMBER 2- 6 2015 | CAPE TOWN, SOUTH AFRICA Congratulations, Fogarty Fellows & Ujala Scholars! Dr. Anita Basavaraj, Ms. Jessica Elf, Dr. Sunita Girish, Dr. Nikhil Gupte, Dr. Aarti Kinikar, Dr. Rahul Lokhande, Dr. Jyoti...

Amid international growth, emocha gets grant to look at Maryland TB treatment

Post Date: 
2015-11-23
Source: 
Technical.ly Baltimore
emocha Mobile Health received a Small Business Innovation Research grant to further development of its mobile app that provides video-based healthcare observations in some cases where visits were previously required. The NIH grant, which is for about $200,000 over two years, will allow the Johns...

New cases of HIV in India could fall by 38% with early ART and better retention, finds study

Post Date: 
2015-10-23
Source: 
The BMJ
Starting antiretroviral therapy (ART) early in India could reduce new infections by 18% and AIDS mortality by 9%, a study has found. Better retention in care could reduce new cases by 38% over the next 20 years. The study used dynamic compartmental modelling to compare early ART initiation (at CD4...

CCGHE Faculty and Fogarty Scholars Meet with BJGMC Leadership

Post Date: 
2015-06-22
Baltimore, MD—Dr. Ajay S. Chandanwale, Dean, and other faculty leadership of Byramjee Jeejeebhoy Government Medical College (BJGMC) in Pune, India, arrived at the Johns Hopkins Medical Campus today to meet with CCGHE faculty and Fogarty Scholars who are in Baltimore attending the Hopkins Summer...

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