Research News

Remdesivir vials
March 24, 2021

Just Published in JAMA Network Open: In this retrospective analysis, remdesivir was associated with faster clinical improvement of COVID-19 in a cohort of predominantly non-White patients

Clinical Research

Leadership
While we conduct research all over the world, the majority of our work is in India. Our Indo-JHU Clinical Research Partnership is located in Pune and is directed by Dr. Amita Gupta (Baltimore, MD), with onsite direction from Dr. Vidya Mave, Dr. Nishi Suryavanshi, and Dr. Nikhil Gupte (Pune). The Indo-JHU Partnership employs more than 200 people and in addition to our memberships in cosortia with many esteemed Indian research institutions, we have formal agreements with:

 
 

Risk Factors for Unfavourable Treatment Outcomes among Multidrug-Resistant Tuberculosis Patients in Public Sector Treatment in Pune

Post Date: 
2017-03-29
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This study is funded and conducted under the U.S. National Institutes of Health, Fogarty International Center. This study seeks to identify risk factors associated with unfavourable treatment outcomes (death, treatment failure, default, XDR-TB) among multidrug-resistant tuberculosis (MDR-TB)...

MDR-TB Free: Monitoring Adverse Effects, Utilizing Resources Optimally, Knowing Resistance Patterns, and Treatment Strategy

Post Date: 
2017-03-24
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This study is also known as MDR-TB MUKT: M onitoring Adverse Effects, U tilizing Resources Optimally, K nowing Resistance Patterns, and T reatment Strategy. Purpose: To establish an observational cohort of MDR-TB cases and household contacts with accompanying biorepository at PD Hinduja National...

Biomarkers for Tuberculosis Diagnosis and Treatment Response

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2017-03-24
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This study is conducted by the Cohort for Tuberculosis Research by the Indo-US Medical Partnership (C-TRIUMPH) under the Regional Prospective Observational Research for Tuberculosis (RePORT) Network, an international TB consortium. Aims: To develop non-sputum, blood-based tools for TB diagnosis and...

Impact of HIV and Diabetes Mellitus on TB Drug Resistance and Recurrence

Post Date: 
2017-03-02
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This study was terminated in January 2021. Tuberculosis (TB) is the leading cause of mortality globally. With increasing burden of HIV and diabetes mellitus (DM), there is a critical need to understand the microbial response and ensuing disease dynamics of TB in the HIV-infected and diabetic host...

Multicenter Study of the Accuracy of the BD MAX MDR-TB Assay for Detection of M. tuberculosis Complex and Mutations Associated with Resistance to Rifampin or Isoniazid

Post Date: 
2017-03-01
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In a multi-country study, we are assessing the accuracy of the BD MAX rapid MDR-TB assay to detect rifampin and isoniazid resistance.

TREAT Asia Pediatric HIV Observational Database

Post Date: 
2017-02-09
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Studies conducted under the TREAT Asia Network and funded by amfAR. TREAT Asia Pediatric HIV Observational Database (TApHOD) is a collaborative observational cohort study of infants, children, and adolescents living with HIV. TApHOD study participants are enrolled and followed at selected TREAT...

TREAT Asia Observational Database

Post Date: 
2017-02-09
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Study conducted under the TREAT Asia Network and funded by amfAR. The TREAT Asia Observational Database's primary study objective is to: Examine HIV natural history, including the relationship between access to ART, demographics, and disease progression; short- and long-term responses to ART;...

Shorter Treatment for Minimal TB in Children (SHINE)

Post Date: 
2017-01-17
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This is a multicountry study being conducted in India, South Africa, Uganda, and Zambia. The principal objective is to determine whether the standard 6 month regimen (8 weeks HRZ(E) followed by 16 weeks HR) can be reduced with similar efficacy, to 4 months (8 weeks HRZ(E) followed by 8 weeks HR),...

Healthcare-Associated Sepsis in the Neonatal Intensive Care Unit in Pune, India

Post Date: 
2017-01-17
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This study is part of CDC's Safe Healthcare, Epidemiology, and Prevention Research Development (SHEPheRD) Program under Domain 7: International HAI and Other Adverse Healthcare Event Prevention. Johns Hopkins neonatologist Dr. Julia Johnson is lead investigator for a systematic study of the...

Bacterial Antimicrobial Resistance Patterns in Pune, India: Substudy on the Introduction of Triage to a Triage Naïve Emergency Department in Pune, India, and the Effects on Patient Flow

Post Date: 
2017-01-01
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Despite state-of-the-art inpatient facilities, Sassoon General Hospital (SGH) in Pune, India, does not currently have a method of triaging the large volume of patients they care for on a daily basis. Based on prior studies in low to middle income countries with underdeveloped emergency medical...

LaMocha: A Mobile Technology to Promote HIV Testing among Immigrant Latino Men

Post Date: 
2016-12-15
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Foreign-born Latino males have a high risk of late HIV diagnosis and presentation to care, which can lead to poor clinical outcomes and ongoing HIV transmission in the community. We propose to evaluate if tailored videos delivered through a tablet by a Latino Health Worker and regular SMS text...

Prevalence and Risk Factors for Oral Cancer among HIV-Infected Adults

Post Date: 
2016-12-13
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The study is designed as a cross-sectional, single time point study for opportunistic oral cancer screening of HIV-infected and non- HIV adults 21 years or older in an urban hospital. All participants will undergo screening for oral cancer and oral potentially malignant disorders (OPMD) by visual...

Cost-effectiveness of Xpert MTB/RIF for Diagnosing Pulmonary Tuberculosis in HIV-positive Patients

Post Date: 
2016-12-01
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This study was terminated October 8, 2019. This is a prospective cross-sectional study which will be conducted at BJGMC in Pune, India. The aim of this study is to see whether Xpert MTB/RIF is useful for early detection of pulmonary tuberculosis, and therefore cost-effective, as compared with...

The Evaluation of Clinical Profile and Mortality of Children Admitted with Tuberculosis in Pediatric Intensive-Care Unit at Sassoon General Hospitals, Pune

Post Date: 
2016-10-27
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This study was terminated October 27, 2019. Tuberculosis (TB) is one of the most common causes of infection-related death globally. TB was declared global public health emergency in 1993 by World HealthOrganization (WHO). Mortality due to TB is increasing due to emergence of multidrug resistant (...

Transcriptomic and Metabolomic Analysis of Microbiologically Confirmed Pediatric Tuberculosis Patients and Uninfected Household Contacts

Post Date: 
2016-09-01
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This study was terminated in June 2020. This study is using stored samples from the Cohort for Tuberculosis Research by the Indo-US Medical Partnership (C-TRIUMPH), under the Regional Prospective Observational Research for Tuberculosis (RePORT) Network, an international TB consortium. The...

Establishing an Observational Cohort Database for Patient Care and Research at the Hinduja Hospital Chest Clinic

Post Date: 
2016-08-30
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India has the largest burden of global tuberculosis (TB), accounting for one quarter of the total number of cases reported. Together with South Africa, India sees one-third of the total number of deaths from TB. Drug-resistant strains of the disease are also on the rise, with India having one of...

Measuring TB Drugs in Hair as a Tool to Monitor Adherence, Exposure and Response in Patients with HIV

Post Date: 
2016-08-16
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Our study will examine whether hair levels of two key first line tuberculosis drugs will be useful markers to identify individuals at highest risk of treatment failure in active tuberculosis. Our study aims to provide a lowcost clinical tool using hair that can be noninvasively collected to monitor...

mHealth-enhanced Peer Navigation Intervention for PrEP Delivery among MSM at STD Clinics

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2016-08-01
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Using mixed methodology (quantitative surveys, qualitative interviews, and administrative data), this study will assess acceptability and feasibility of an mHealth-enhanced peer navigation to promote PrEP initiation, retention and adherence among men who have sex with men (MSM) in the Baltimore...

Adherence to Indian National Guidelines for Isoniazid Chemoprophylaxis among Pediatric Contacts of Pulmonary Tuberculosis Cases

Post Date: 
2016-07-06
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This study was terminated June 19, 2019. The primary objective of the study was to assess the implementation of the Indian Revised National Tuberculosis Programme's (RNTCP) guidelines regarding isoniazid preventive treatment (IPT) for children under 6 years of age who had been in contact with...

TB and Pregnancy Impact of Immune Changes of HIV and Stages of Pregnancy on Tuberculosis: Nested Study on Temporal Dynamics of Gut Microbiota in HIV Infected Pregnant Women

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2016-07-05
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This is a nested prospective longitudinal cohort study of 35 HIV-infected and 35 HIV-noninfected pregnant women who are part of the parent study “Impact of Immune Changes of HIV and Stages of Pregnancy on Tuberculosis." The objectives are to: Determine the association of gestational age with...

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Impact of combination HIV interventions on HIV incidence in hyperendemic fishing communities in Uganda: a prospective cohort study

Post Date: 
2019-09-15
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Publication: 
Lancet HIV
Background: Targeting combination HIV interventions to locations and populations with high HIV burden is a global priority, but the impact of these strategies on HIV incidence is unclear. We assessed the impact of combination HIV interventions on HIV incidence in four HIV-hyperendemic communities...

Cell Phones, Sexual Behaviors and HIV Prevalence in Rakai, Uganda: A Cross Sectional Analysis of Longitudinal Data

Post Date: 
2019-09-13
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Publication: 
AIDS and Behavior
Abstract Cell phones have increased communication and connection across the globe and particularly in sub-Saharan Africa-with potential consequences for the HIV epidemic. We examined the association among ownership of cell phones, sexual behaviors (number of sexual partners, alcohol use before sex...

Re: A Shorter Regimen for Rifampin-Resistant Tuberculosis

Post Date: 
2019-09-12
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Publication: 
New England Journal of Medicine
Dr. Jeff Tornheim and colleagues respond to an NEJM article about shorter course TB treatment.

Evaluation of miLINC to shorten time to treatment for rifampicin-resistant Mycobacterium tuberculosis

Post Date: 
2019-09-01
Publication: 
The International Journal of Tuberculosis and Lung Disease
A suite of mobile health applications shows promise for linking more drug-resisitant TB patients to care and in less time.

Use of smartphone-based video Directly Observed Therapy (vDOT) in tuberculosis care: Single-arm, prospective feasibility study

Post Date: 
2019-08-30
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Publication: 
Journal of Medical Internet Research
Video-based monitoring is increasingly used as an efficient and low cost alternative to in-person observation and monitoring of TB patients. It showed promise in the high TB setting of India, too.

Inclusion of key populations in clinical trials of new antituberculosis treatments: Current barriers and recommendations for pregnant and lactating women, children, and HIV-infected persons

Post Date: 
2019-08-15
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Publication: 
PLOS Medicine
PLOS Medicine: Dr. Amita Gupta and colleagues discuss the scientific and ethical basis for including pregnant and lactation women, children, and HIV+ patients in tuberculosis therapeutic clinical trials.

A tuberculosis-free world: is it a delusion?

Post Date: 
2019-08-12
Publication: 
The Lancet
The Lancet: Dr. Sachin Atre's correspondence questions progress and global commitment toward TB elimination.

Smoking, alcohol use disorder and tuberculosis treatment outcomes: A dual co-morbidity burden that cannot be ignored

Post Date: 
2019-07-31
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PLoS One
BACKGROUND: More than 20% of tuberculosis (TB) disease worldwide may be attributable to smoking and alcohol abuse. India is the second largest consumer of tobacco products, a major consumer of alcohol particularly among males, and has the highest burden of TB globally. The impact of...

Third-line antiretroviral therapy in low-income and middle-income countries (ACTG A5288): a prospective strategy study

Post Date: 
2019-07-29
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Publication: 
Lancet HIV
BACKGROUND: Antiretroviral therapy (ART) management is challenging for individuals in resource-limited settings presenting for third-line treatment because of complex resistance patterns, partly due to reduced access to viral load monitoring. We aimed to evaluate use of newer...

Infection free "resisters" among household contacts of adult pulmonary tuberculosis

Post Date: 
2019-07-18
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Publication: 
PLoS One
Despite substantial exposure to infectious pulmonary tuberculosis (TB) cases, some household contacts (HHC) never acquire latent TB infection (LTBI). Characterizing these "resisters" can inform who to study immunologically for the development of TB vaccines. We enrolled HHCs of culture-...

The Right and Left Hands of the State — Two Patients at Risk of Deportation

Post Date: 
2019-07-18
Publication: 
New England Journal of Medicine
NEJM: Dr. Kathleen Page and colleagues offer guidance for clinicians on meeting the needs of patients in an era of punitive immigration policy

HIV-ASSIST

Post Date: 
2019-07-16
Publication: 
HIVSpecialist
HIVSpecialist: Dr. Maunank Shah and colleagues chronicle the development of HIV-ASSIST, a tool to help guide selections for patient-centered antiretroviral therapy.

Long-acting or extended-release antiretroviral products for HIV treatment and prevention in infants, children, adolescents, and pregnant and breastfeeding women: knowledge gaps and research priorities

Post Date: 
2019-07-15
Publication: 
Lancet HIV
Lancet HIV : This paper summarizes findings of the Long acting/Extended Release Antiretroviral Resource Program workshop, and offers recommendations for developing ARV products for HIV treatment and prevention in infants, children, adolescents, and pregnant and breastfeeding women

Advancing the development of new tuberculosis treatment regimens: The essential role of translational and clinical pharmacology and microbiology

Post Date: 
2019-07-15
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Publication: 
PLoS Medicine
Summary points Translational and clinical pharmacology are the state-of-the-art tools used by drug developers to efficiently move compounds and regimens through all drug development phases. Tuberculosis drug and regimen development, though, has traditionally underutilized these modern, model-based...

Advancing the development of new tuberculosis treatment regimens: The essential role of translational and clinical pharmacology and microbiology

Post Date: 
2019-07-05
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Publication: 
PLOS
Application of clinical pharmacology best practices is essential to the efficient and rational development of drugs. In general, knowledge gained about exposure–response relationships in preclinical models aids drug and dose selection in human studies, and biomarkers and pharmacokinetic (PK) data...

Mobile phone access and comfort: implications for HIV and tuberculosis care in India and South Africa.

Post Date: 
2019-07-01
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Publication: 
International Journal of Tuberculosis and Lung Disease
SETTING: India and South Africa shoulder the greatest burden of tuberculosis (TB) and human immunodeficiency virus (HIV) infection respectively, but care retention is suboptimal. OBJECTIVE: We conducted a study in Pune, India, and Matlosana, South Africa ...

Advancing Patient-Centered Care in Tuberculosis Management: A Mixed-Methods Appraisal of Video Directly Observed Therapy

Post Date: 
2019-06-25
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Countries: 
Publication: 
Open Forum Infectious Diseases
OFID : Study compared directly-observed therapy with video-based observed therapy using the emocha mobile health platform

Age-specific prevalence of TB infection among household contacts of pulmonary tuberculosis: Is it time for TB preventive therapy?

Post Date: 
2019-06-21
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Publication: 
Transactions of the Royal Society of Tropical Medicine and Hygiene
BACKGROUND: Household contacts (HHCs) of TB patients are at high risk of developing evidence of latent TB infection (LTBI) and active disease from the index patient. We estimated the age-specific prevalence of LTBI and the force of infection (FI), as a measure of recent transmission, among HHCs of...

Users beware! Biological variation in complete blood counts over short time intervals

Post Date: 
2019-05-29
Publication: 
BMJ Evidence Based Medicine
New publication in BMJ Evidence Based Medicine looks at CBC count variations in blood drawn over a short time period

Assessment of lung function in successfully treated tuberculosis reveals high burden of ventilatory defects and COPD

Post Date: 
2019-05-23
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Publication: 
PLoS One
New in PLoS One: We found a high burden of lung function defects and COPD in tuberculosis cases who successfully completed treatment, suggesting a need for lung function screening as part of patient management.

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Linezolid Experience Among MDR-TB Patients in Mumbai

Post Date: 
2018-03-16
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Tornheim J. Linezolid Experience Among MDR-TB Patients in Mumbai. 2018 Research Retreat, Johns Hopkins Department of Medicine. Baltimore, MD. 2018.

Similar Clinical Outcomes Between Formula and Breastfeeding Women In PROMISE

Post Date: 
2018-03-07
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Hoffman RM , Angelidou K, Brummel S, Saidi F, Dula DE, Mave V, Fairlie L, Theron G, Kamateeka M, Chipato T, Violari A, Chakhtoura N, Currier JS, Fowler MG, for the IMPAACT PROMISE 1077BF/FF Team. Similar Clinical Outcomes Between Formula and Breastfeeding Women In PROMISE. CROI 2018. Boston,...

Randomized Trial of Safety of Isoniazid Preventive Therapy During or After Pregnancy

Post Date: 
2018-03-07
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Clinical Sites: 
Gupta A, Montepiedra G, Aaron L, Theron G, McCarthy K, Onyango-Makumbi C, Chipate T, Masheto G, Shin K, Zimmer B, Sterling TR, Chakhtoura N, Jean-Philippe P, Weinberg A for the IMPAACT P1078/TB APPRISE Study Team. Randomized Trial of Safety of Isoniazid Preventive Therapy During or After Pregnancy...

GLP-1 and C-Peptide are Associated with Insulin Resistance among PLWH in India

Post Date: 
2018-03-07
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Marbaniang I, Sangle S, Kadam D, Kulkarni V, Shere D, Gupte N, Gupta A, Mave V. GLP-1 and C-Peptide are Associated with Insulin Resistance among PLWH in India. CROI 2018. Boston, MA. 2018

Inflammation in HIV-Infected Pregnant Women is Associated with Pre-term Birth

Post Date: 
2018-03-07
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Shivakoti R , Gupte N, Kumar NP, Kulkarni V, Balasubramanian U, Bhosale R, Sambarey P, Kinikar A, Bharadwaj R, Patil S, Inamdar S, Suryavanshi N, Babu S, Bollinger R, Gupta A. Inflammation in HIV-Infected Pregnant Women is Associated with Pre-term Birth. CROI 2018. Boston, MA. 2018

One Month of Rifapentine/Isoniazid to Prevent TB In People With HIV: Brief-TB/A5279

Post Date: 
2018-03-05
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Swindells S, Ramchandani R, Gupta A, Benson CA, Leon-Cruz JT, Omoz-Oarhe A, Juste MAJ, Lama JR, Valencia JA, Badal-Faesen S, Moran LE, Fletcher CV, Nuermberger E, Chaisson RE. One Month of Rifapentine/Isoniazid to Prevent TB In People With HIV: Brief-TB/A5279. CROI 2018. Boston, MA. 2018

Clinical Profile of Tuberculous Meningitis in a Tertiary Care Center in India. 5th Global Forum on TB Vaccines. New Delhi, India

Post Date: 
2018-02-21
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Basavaraj A. Clinical Profile of Tuberculous Meningitis in a Tertiary Care Center in India. Poster presented at 5th Global Forum on TB Vaccines. New Delhi, India. February 20-23, 2018.

Infection Free “Resistors” among Household Contacts of Culture-Confirmed Adult Pulmonary TB Cases

Post Date: 
2018-02-21
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Mave V , Chandrasekaran P, Paradkar M, Gupte A, Pradhan N, Kannan GN, Shivakumar SVBY, Kulkarni V, Dhanasekaran K, Subramanyam B, Selvaraju S, Murali L, Bharadwaj R, Gaikwad S, Meshram S, Kinikar A, Hanna LE, Swaminathan S, Gupte N, Gupta A. Infection Free “Resistors” among Household Contacts of...

TB Infection Among Household Contacts: Preventive Therapy for All?

Post Date: 
2018-02-21
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Dolla CK, Paradkar M, Gupte A, Thiruvenkadam K, Gupte N, Kulkarni A, Balasubranian U, Hanna LE, Dhanasekaran K, Bharadwaj R, Shivakumar SVBY, Gaikwad S, Meshram S, Kohli R, Lokhande R, Thomas B, Kinikar A, Swaminathan S, Mave V, Gupta A, Chandrasekaran P. TB Infection Among Household Contacts:...

Incidence of Mycobacterium tuberculosis Infection among Household Contacts of Adult Pulmonary Tuberculosis Cases in India

Post Date: 
2018-02-20
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Selvaraju S, Thiruvenkadam K, Paradkar M , Marinaik SB, Bharadwaj R, Rajagopalan S, Gaikwad S, Pattabiraman S, Kinikar A, Sivaramakrishnan GN, Meshram S, Hanna LE, Lokhande R, Dhanasekaran K, Gupte A, John S, Gupte N, Thomas B, Kukarni V, Ayyanu S, Kohli R, Shivakumar SVBY, Swaminathan S, Mave V,...

Hyperhomocysteinemia Screening: A Missed Opportunity to Mitigate CVD Risk among Asian Indian HIV-infected Adults?

Post Date: 
2017-12-28
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Marbaniang I , Sangle S, Kulkarni V, Deshpande P, Shere D, Gupte N, Gupta A, Mave V. Hyperhomocysteinemia Screening: A Missed Opportunity to Mitigate CVD Risk among Asian Indian HIV-infected Adults? AAPI Global Health Summit. American Association of Physicians of Indian Origin. Kolkata, India.

Leveraging Collective Impact to Promote India's Development: The Role of the Indian Diaspora in the Fight Against Tuberculosis

Post Date: 
2017-11-09
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Gupta, A. Leveraging Collective Impact to Promote India's Development: The Role of the Indian Diaspora in the Fight Against Tuberculosis. Roundtable Event. USAID, American India Foundation, Dasra, Indiaspora, Intellecap. Georgetown University, Washington, DC.

Meet the Expert: Managing Tuberculosis in Pregnant Women and Newborns

Post Date: 
2017-10-13
Gupta A. Meet the Expert: Managing Tuberculosis in Pregnant Women and Newborns. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico.

A Study to Compare Efficacy of Oral High Dose Rifampicin with Standard Dose Rifampicin in Tuberculous Meningitis

Post Date: 
2017-10-13
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Clinical Sites: 
Basavaraj A , Avhad A, Kadam D. A Study to Compare Efficacy of Oral High Dose Rifampicin with Standard Dose Rifampicin in Tuberculous Meningitis. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico. October 13, 2017.

Prevalence of Vitamin D Deficiency among Indian Children with Tuberculosis and Age- and Sex-matched Controls

Post Date: 
2017-10-13
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Clinical Sites: 
Kinikar A , Chandanwale A, Dixit S, Jubilus J, Jain S, Bharadwaj R, Mave V, Gupte N, DeLuca A, Gupta A, Bollinger RC. Prevalence of Vitamin D Deficiency among Indian Children with Tuberculosis and Age- and Sex-matched Controls. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico...

Lack of TB Knowledge Among TST-Positive Household Contacts of Pulmonary Cases: A Missed Opportunity

Post Date: 
2017-10-13
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Clinical Sites: 
DeLuca A , Dhumal G, Paradkar M, Suryavanshi N, Mave V, Kohli R, Shivakumar SVBY, Gupta A. Lack of TB Knowledge Among TST-Positive Household Contacts of Pulmonary Cases: A Missed Opportunity. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico.

The ACTG IMPAACT PHOENIx Feasibility Study: Implications for Country Programs

Post Date: 
2017-10-13
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Gupta A. The ACTG IMPAACT PHOENIx Feasibility Study: Implications for Country Programs. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico.

Delays and Barriers to Early Treatment Initiation for Childhood Tuberculosis in India

Post Date: 
2017-10-13
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Clinical Sites: 
Valvi C , Chandanwale A, Khadse A, Kulkarni R, Kadam D, Dhumal G, Bollinger RC, Deluca A. Delays and Barriers to Early Treatment Initiation for Childhood Tuberculosis in India. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico. October 13, 2017.

Accessing MDR-TB Exposed Households: the PHOENiX MDR-TB Feasibility Study

Post Date: 
2017-10-13
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Clinical Sites: 
Gupta A. Accessing MDR-TB Exposed Households: the PHOENiX MDR-TB Feasibility Study. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico.

Biological Differences in Tuberculosis Diagnosis and Disease in Women

Post Date: 
2017-10-12
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Clinical Sites: 
Mathad J. Biological Differences in Tuberculosis Diagnosis and Disease in Women. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico.

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Shah Receives Dr. David Glasser Memorial Award for TB Control in Maryland

Post Date: 
2018-04-27
Award recognizes significant contributions to TB prevention & control in MD.

Smartphone App Keeps an ‘Eye’ on Daily Tuberculosis Therapy

Post Date: 
2018-04-26
Johns Hopkins Medicine logo
Study shows success with TB therapy observation conducted via video instead of via in-person clinic visits.

World Tuberculosis (TB) Day Recognized with Community Event at BJGMC

Post Date: 
2018-04-17
World Health Day group activities at BJGMC Clinical Research Site in Pune, India
This year's themes: Maintaining healthy nutrition, addressing mental health challenges, and the latest in TB research.

Adverse pregnancy outcomes with isoniazid preventive therapy in HIV

Post Date: 
2018-03-09
Source: 
Infectious Disease Advisor
. . . The safety of IPT in pregnant women with HIV is unknown, especially with regard to its combination with highly active antiretroviral therapy (ART). Amita Gupta, MD, deputy director of the Johns Hopkins University Center for Clinical Global Health Education at the Johns Hopkins...

No difference in safety for HIV+ pregnant women deferring TB Tx

Post Date: 
2018-03-09
Source: 
MedPage Today
First randomized clinical trail of IPT in pregnant and postpartum women may suggest need for WHO guideline change.

Preventive TB therapy during pregnancy causes excessive adverse events

Post Date: 
2018-03-08
Source: 
Healio Infectious Disease News
. . . “Identifying ways to prevent TB during pregnancy and the postpartum period is a really important way to address maternal and infant health for a globally important disease such as tuberculosis,” Amita Gupta, MD, MHS, associate professor of medicine and international health and deputy director...

Study Results for IMPAACT P1078 Presented at CROI 2018

Post Date: 
2018-03-07
Source: 
IMPAACT Network News
IMPAACT Network News: Dr. Amita Gupta presented findings at CROI 2018.

One-Month Tuberculosis Prophylaxis as Effective as Nine-Month Regimen for People Living with HIV

Post Date: 
2018-03-05
National Institutes of Health Logo
The Indo-JHU Clinical Research Partnership participated in this important study that could change TB prevention for people living with HIV.

CCGHE at CROI 2018

Post Date: 
2018-03-05
Check out where and when CCGHE presented at the Conference on Retroviruses and Opportunistic Infections. One Month of Rifapentine/Isoniazid to Prevent TB In People With HIV: Brief-TB/A5279 Swindells S, Ramchandani R, Gupta A, Benson CA, Leon-Cruz JT, Omoz-Oarhe A...

Tip Sheet: Johns Hopkins Researchers Present at Annual CROI Meeting

Post Date: 
2018-03-01
Newswise — Amita Gupta, M.D., deputy director of the Johns Hopkins University Center for Clinical Global Health Education at the Johns Hopkins University School of Medicine, will present a multicounty study of preventive treatment for tuberculosis (TB) in HIV-infected pregnant and postpartum women—...

2017 Year in Review

Post Date: 
2018-02-19
What a year! Our 2017 Year In Review outlines the most ambitious 365 days we’ve had to date.

WHO sets disease priorities for 2018; Tuberculosis once again not included

Post Date: 
2018-02-15
Source: 
Contagion Live: Infectious Diseases Today
CCGHE Director Bob Bollinger weighs in on WHO's priority pathogens for 2018.

The Health App that Beat Hurricane Harvey

Post Date: 
2018-01-18
Source: 
Politico
CCGHE invented the emocha Mobile Health platform, and it's changing the way tuberculosis patients are cared for.

Notes from the Field: Use of Asynchronous Video Directly Observed Therapy for Treatment of Tuberculosis and Latent Tuberculosis Infection in a Long-Term–Care Facility ― Puerto Rico, 2016–2017

Post Date: 
2017-12-22
Source: 
Morbidity and Mortality Weekly Report
emocha's video Directly Observed Therapy is highlighted in this report.

Upstarts: A Better Blood Test?

Post Date: 
2017-12-15
Source: 
JHU Engineering Impact
The miLAB handheld diagnostic project led by Dr. Bob Bollinger is the feature of this report.

Celebrating Johns Hopkins Medicine's impact in India

Post Date: 
2017-12-13
Source: 
The Campaign for Johns Hopkins Medicine
In 4 years, the CCGHE has tripled its capacity for conducting research on grave health threats, thanks to strong philanthropic support.

Transforming India from TB Hot Zone to TB Hot Shot

Post Date: 
2017-12-09
Source: 
Indiaspora
Dr. Amita Gupta's invited commentary: Can Indian transform its role in the global TB epidemic?

Combination HIV prevention reduces infections

Post Date: 
2017-12-01
Source: 
MD Magazine
. . . Researchers found that throughout the 7-year period in which rates of treatment and voluntary medical male circumcision increased significantly, HIV incidence dropped by 42% among nearly 18,000 people in Uganda . . .

NIH Statement on World AIDS Day 2017

Post Date: 
2017-12-01
. . . A study published recently in the New England Journal of Medicine found that HIV incidence dropped by 42 percent among nearly 18,000 people in a Ugandan district during a 7-year period when the rates of HIV treatment and voluntary medical male circumcision were significantly increased . . .

4 ways that telemedicine can address the opioid crisis

Post Date: 
2017-12-01
Source: 
The Hill
CCGHE Director Dr. Bob Bollinger describes the utility of telemedicine in this opinion article in The Hill.

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