Research News

Dr. Maunank Shah
September 24, 2021

A new Johns Hopkins Medicine mathematical model to predict how the human immunodeficiency virus (HIV) spreads in urban areas...

Clinical Research

Leadership
While we conduct research all over the world, the majority of our work is in India. Our Indo-JHU Clinical Research Partnership is located in Pune and is directed by Dr. Amita Gupta (Baltimore, MD), with onsite direction from Dr. Vidya Mave, Dr. Nishi Suryavanshi, and Dr. Nikhil Gupte (Pune). The Indo-JHU Partnership employs more than 200 people and in addition to our memberships in cosortia with many esteemed Indian research institutions, we have formal agreements with:

 
 

Multicenter Study of the Accuracy of the BD MAX MDR-TB Assay for Detection of M. tuberculosis Complex and Mutations Associated with Resistance to Rifampin or Isoniazid

Post Date: 
2017-03-01
   |   
Countries: 
   |   
Clinical Sites: 
In a multi-country study, we are assessing the accuracy of the BD MAX rapid MDR-TB assay to detect rifampin and isoniazid resistance.

TREAT Asia Pediatric HIV Observational Database

Post Date: 
2017-02-09
   |   
Countries: 
   |   
Clinical Sites: 
Studies conducted under the TREAT Asia Network and funded by amfAR. TREAT Asia Pediatric HIV Observational Database (TApHOD) is a collaborative observational cohort study of infants, children, and adolescents living with HIV. TApHOD study participants are enrolled and followed at selected TREAT...

TREAT Asia Observational Database

Post Date: 
2017-02-09
   |   
Countries: 
   |   
Clinical Sites: 
Study conducted under the TREAT Asia Network and funded by amfAR. The TREAT Asia Observational Database's primary study objective is to: Examine HIV natural history, including the relationship between access to ART, demographics, and disease progression; short- and long-term responses to ART;...

Shorter Treatment for Minimal TB in Children (SHINE)

Post Date: 
2017-01-17
   |   
Countries: 
   |   
Clinical Sites: 
This is a multicountry study being conducted in India, South Africa, Uganda, and Zambia. The principal objective is to determine whether the standard 6 month regimen (8 weeks HRZ(E) followed by 16 weeks HR) can be reduced with similar efficacy, to 4 months (8 weeks HRZ(E) followed by 8 weeks HR),...

Healthcare-Associated Sepsis in the Neonatal Intensive Care Unit in Pune, India

Post Date: 
2017-01-17
   |   
Countries: 
   |   
Clinical Sites: 
This study is part of CDC's Safe Healthcare, Epidemiology, and Prevention Research Development (SHEPheRD) Program under Domain 7: International HAI and Other Adverse Healthcare Event Prevention. Johns Hopkins neonatologist Dr. Julia Johnson is lead investigator for a systematic study of the...

Bacterial Antimicrobial Resistance Patterns in Pune, India: Substudy on the Introduction of Triage to a Triage Naïve Emergency Department in Pune, India, and the Effects on Patient Flow

Post Date: 
2017-01-01
   |   
Countries: 
   |   
Clinical Sites: 
Despite state-of-the-art inpatient facilities, Sassoon General Hospital (SGH) in Pune, India, does not currently have a method of triaging the large volume of patients they care for on a daily basis. Based on prior studies in low to middle income countries with underdeveloped emergency medical...

LaMocha: A Mobile Technology to Promote HIV Testing among Immigrant Latino Men

Post Date: 
2016-12-15
   |   
Countries: 
Foreign-born Latino males have a high risk of late HIV diagnosis and presentation to care, which can lead to poor clinical outcomes and ongoing HIV transmission in the community. We propose to evaluate if tailored videos delivered through a tablet by a Latino Health Worker and regular SMS text...

Prevalence and Risk Factors for Oral Cancer among HIV-Infected Adults

Post Date: 
2016-12-13
   |   
Countries: 
   |   
Clinical Sites: 
The study is designed as a cross-sectional, single time point study for opportunistic oral cancer screening of HIV-infected and non- HIV adults 21 years or older in an urban hospital. All participants will undergo screening for oral cancer and oral potentially malignant disorders (OPMD) by visual...

Cost-effectiveness of Xpert MTB/RIF for Diagnosing Pulmonary Tuberculosis in HIV-positive Patients

Post Date: 
2016-12-01
   |   
Countries: 
   |   
Clinical Sites: 
This study was terminated October 8, 2019. This is a prospective cross-sectional study which will be conducted at BJGMC in Pune, India. The aim of this study is to see whether Xpert MTB/RIF is useful for early detection of pulmonary tuberculosis, and therefore cost-effective, as compared with...

The Evaluation of Clinical Profile and Mortality of Children Admitted with Tuberculosis in Pediatric Intensive-Care Unit at Sassoon General Hospitals, Pune

Post Date: 
2016-10-27
   |   
Countries: 
   |   
Clinical Sites: 
This study was terminated October 27, 2019. Tuberculosis (TB) is one of the most common causes of infection-related death globally. TB was declared global public health emergency in 1993 by World HealthOrganization (WHO). Mortality due to TB is increasing due to emergence of multidrug resistant (...

Transcriptomic and Metabolomic Analysis of Microbiologically Confirmed Pediatric Tuberculosis Patients and Uninfected Household Contacts

Post Date: 
2016-09-01
   |   
Countries: 
   |   
Clinical Sites: 
This study was terminated in June 2020. This study is using stored samples from the Cohort for Tuberculosis Research by the Indo-US Medical Partnership (C-TRIUMPH), under the Regional Prospective Observational Research for Tuberculosis (RePORT) Network, an international TB consortium. The...

Establishing an Observational Cohort Database for Patient Care and Research at the Hinduja Hospital Chest Clinic

Post Date: 
2016-08-30
   |   
Countries: 
   |   
Clinical Sites: 
India has the largest burden of global tuberculosis (TB), accounting for one quarter of the total number of cases reported. Together with South Africa, India sees one-third of the total number of deaths from TB. Drug-resistant strains of the disease are also on the rise, with India having one of...

Measuring TB Drugs in Hair as a Tool to Monitor Adherence, Exposure and Response in Patients with HIV

Post Date: 
2016-08-16
   |   
Countries: 
   |   
Clinical Sites: 
Our study will examine whether hair levels of two key first line tuberculosis drugs will be useful markers to identify individuals at highest risk of treatment failure in active tuberculosis. Our study aims to provide a lowcost clinical tool using hair that can be noninvasively collected to monitor...

mHealth-enhanced Peer Navigation Intervention for PrEP Delivery among MSM at STD Clinics

Post Date: 
2016-08-01
   |   
Countries: 
Using mixed methodology (quantitative surveys, qualitative interviews, and administrative data), this study will assess acceptability and feasibility of an mHealth-enhanced peer navigation to promote PrEP initiation, retention and adherence among men who have sex with men (MSM) in the Baltimore...

Adherence to Indian National Guidelines for Isoniazid Chemoprophylaxis among Pediatric Contacts of Pulmonary Tuberculosis Cases

Post Date: 
2016-07-06
   |   
Countries: 
   |   
Clinical Sites: 
This study was terminated June 19, 2019. The primary objective of the study was to assess the implementation of the Indian Revised National Tuberculosis Programme's (RNTCP) guidelines regarding isoniazid preventive treatment (IPT) for children under 6 years of age who had been in contact with...

TB and Pregnancy Impact of Immune Changes of HIV and Stages of Pregnancy on Tuberculosis: Nested Study on Temporal Dynamics of Gut Microbiota in HIV Infected Pregnant Women

Post Date: 
2016-07-05
   |   
Countries: 
   |   
Clinical Sites: 
This is a nested prospective longitudinal cohort study of 35 HIV-infected and 35 HIV-noninfected pregnant women who are part of the parent study “Impact of Immune Changes of HIV and Stages of Pregnancy on Tuberculosis." The objectives are to: Determine the association of gestational age with...

A Randomized Therapeutic Interventional Comparative Study between Three Different Modalities of Paediatric Antitubercular Treatment

Post Date: 
2016-06-13
   |   
Countries: 
   |   
Clinical Sites: 
This study was terminated July 6, 2019. It was funded by the Fogarty International Center at the U.S. National Institutes of Health. This study evaluated three different TB treatment regimens in children attending Sassoon General Hospital in Pune, India. A convenience sample size of n=100 children...

Optimal Algorithmic Diagnosis of Genital TB among HIV-infected and Uninfected Infertile Women

Post Date: 
2016-05-26
   |   
Countries: 
   |   
Clinical Sites: 
This study was terminated March 2020. It was funded by the Fogarty International Center at the U.S. National Institutes of Health. There is a lack of a set protocol universally for diagnosis of genital TB, and for Indian hospitals, India's Revised National Tuberculosis Control Program (RNTCP) also...

Whole Genome Sequencing and Trek Sensititre Testing of Stored Isolates of Drug-resistant Tuberculosis from a Clinical Cohort at Hinduja Hospital, Mumbai

Post Date: 
2016-05-02
   |   
Countries: 
   |   
Clinical Sites: 
Among HIV-positive TB patients presenting to Médecins San Frontières (MSF) clinics in Mumbai, 78% carried MDR-TB strains, with nearly half also found to have additional drug resistance. A previously published cohort of 202 patients cared for at these MSF clinics have enrolled in a cross-sectional...

Comparison of Available Purified-protein Derivative (PPD) Tuberculin Skin Test (TST) Antigen Solutions in Detecting Latent Tuberculosis Infection in India

Post Date: 
2016-04-21
   |   
Countries: 
   |   
Clinical Sites: 
This study is conducted by the Cohort for Tuberculosis Research by the Indo-US Medical Partnership (C-TRIUMPH) under the Regional Prospective Observational Research for Tuberculosis (RePORT) Network, an international TB consortium. Given the worldwide shortage of PPD TST antigen solutions, it is...

Pages

Age-specific prevalence of TB infection among household contacts of pulmonary tuberculosis: Is it time for TB preventive therapy?

Post Date: 
2019-06-21
   |   
Countries: 
Publication: 
Transactions of the Royal Society of Tropical Medicine and Hygiene
BACKGROUND: Household contacts (HHCs) of TB patients are at high risk of developing evidence of latent TB infection (LTBI) and active disease from the index patient. We estimated the age-specific prevalence of LTBI and the force of infection (FI), as a measure of recent transmission, among HHCs of...

Users beware! Biological variation in complete blood counts over short time intervals

Post Date: 
2019-05-29
Publication: 
BMJ Evidence Based Medicine
New publication in BMJ Evidence Based Medicine looks at CBC count variations in blood drawn over a short time period

Assessment of lung function in successfully treated tuberculosis reveals high burden of ventilatory defects and COPD

Post Date: 
2019-05-23
   |   
Countries: 
Publication: 
PLoS One
New in PLoS One: We found a high burden of lung function defects and COPD in tuberculosis cases who successfully completed treatment, suggesting a need for lung function screening as part of patient management.

Subtherapeutic rifampicin concentration is associated with unfavourable tuberculosis treatment outcomes

Post Date: 
2019-05-10
   |   
Countries: 
Publication: 
Clinical Infectious Diseases
Rifampicin concentrations were sub-therapeutic in most Indian patients taking a thrice-weekly TB regimen

Venezuela's Public Health Crisis: A Regional Emergency

Post Date: 
2019-04-11
   |   
Countries: 
Publication: 
Lancet
The Lancet: The economic crisis in Venezuela has eroded the country's health-care infrastructure and threatened public health.

The burden of diabetes in India

Post Date: 
2019-04-01
   |   
Countries: 
Publication: 
The Lancet Global Health
The India State-Level Disease Burden Initiative Diabetes Collaborators (December, 2018)1 provide a comprehensive overview of the diabetes burden in India. The authors point out some limitations in estimates due to inadequacies in the data. Nevertheless, on the basis of my field experience in India...

A population pharmacokinetic analysis shows that arylacetamide deacetylase (AADAC) gene polymorphism and HIV infection affect the exposure of rifapentine

Post Date: 
2019-03-29
   |   
Countries: 
Publication: 
Antimicrobial Agents Chemotherapy
New analysis published in Antimicrobial Agents and Chemotherapy!

Feasibility of identifying household contacts of rifampin- and multidrug-resistant tuberculosis cases at high risk of progression to tuberculosis disease

Post Date: 
2019-03-28
   |   
Countries: 
Publication: 
Clinical Infectious Diseases
We assessed multidrug-resistant tuberculosis (MDR-TB) cases and their household contacts (HHCs) to inform the development of an interventional clinical trial.

Willingness to take multidrug-resistant tuberculosis (MDR-TB) preventive therapy among adult and adolescent household contacts of MDR-TB index cases: an international multi-site cross-sectional study

Post Date: 
2019-03-28
   |   
Countries: 
Publication: 
Clinical Infectious Diseases
Abstract BACKGROUND: Household contacts (HHCs) of individuals with multidrug-resistant tuberculosis (MDR-TB) are at high risk of infection and subsequent disease. There is limited evidence on the willingness of MDR-TB HHCs to take MDR-TB preventive therapy (TPT) to decrease their risk of TB disease...

Building the framework for standardized clinical laboratory reporting of next generation sequencing data for resistance-associated mutations in Mycobacterium tuberculosis complex

Post Date: 
2019-03-18
Publication: 
Clinical Infectious Diseases
Abstract Tuberculosis is the primary infectious disease killer worldwide, with a growing threat from multidrug- resistant cases. Unfortunately, classic growth-based phenotypic drug susceptibility testing (DST) remains difficult, costly and time-consuming, while current rapid molecular testing...

Evaluation of an adapted Project Connect community based intervention among professionals serving young minority men

Post Date: 
2019-03-15
   |   
Countries: 
Publication: 
Sexually Transmitted Diseases
BACKGROUND: To address sexual and reproductive health (SRH) needs of young minority urban males, we developed and evaluated Project Connect Baltimore (Connect), which was adapted from a program with demonstrated effectiveness among young females. The objectives were to determine (1) the...

One month of rifapentine plus isoniazid to prevent HIV-related tuberculosis

Post Date: 
2019-03-14
Publication: 
New England Journal of Medicine
Exciting findings from A5279: One month of Rifapentine with isonaizid is as effective as a 9-month course of isoniazid alone!

Elevated highly sensitive C-reactive protein and d-dimer levels are associated with food insecurity among people living with HIV in Pune, India

Post Date: 
2019-03-04
   |   
Countries: 
   |   
Clinical Sites: 
Publication: 
Public Health Nutrition
Abstract OBJECTIVE: To assess the prevalence and determinants of food insecurity among people living with HIV (PLWH) in Pune, India and its association with biomarkers known to confer increased risks of morbidity and mortality in this population. DESIGN:...

Prevalence, predictors, and successful treatment outcomes of Xpert MTB/RIF-identified rifampicin-resistant tuberculosis in post-conflict Eastern Democratic Republic of the Congo, 2012-2017: A retrospective province-wide cohort study

Post Date: 
2019-02-13
   |   
Publication: 
Clinical Infectious Diseases
BACKGROUND: Multidrug-resistant tuberculosis (MDR-TB) jeopardizes global TB control. The prevalence and predictors of Rifampicin-resistant (RR) TB, a proxy for MDR-TB, and the treatment outcomes with standard and shortened regimens have not been assessed in post-conflict regions, such...

Female global health leadership: Data-driven approaches to close the gender gap

Post Date: 
2019-02-09
   |   
Countries: 
   |   
Clinical Sites: 
Publication: 
The Lancet
Lancet article investigates gender-based challenges of female health trainees and professionals and identifies interventions

Few eligible for the newly recommended short course MDR-TB regimen at a large Mumbai private clinic

Post Date: 
2019-01-28
   |   
Countries: 
   |   
Clinical Sites: 
Publication: 
BMC Infectious Diseases
BACKGROUND: India has the world's highest tuberculosis burden, and Mumbai is particularly affected by multidrug resistant tuberculosis (MDR-TB). WHO recommends short, intensive treatment ("Short Course") for previously untreated pulmonary MDR-TB patients but does not require universal...

Symptom screening for active tuberculosis in pregnant women living with HIV

Post Date: 
2019-01-24
Publication: 
Cochrane Database of Systematic Reviews
This is a protocol for a Cochrane Review (Diagnostic test accuracy). The objectives are as follows: To assess the accuracy of the four-symptom screen (cough, fever, night sweats, or weight loss) for identifying active TB in pregnant PLHIV who are screened in an outpatient or community setting...

Preventable losses: Infant mortality increases in Venezuela

Post Date: 
2019-01-24
Publication: 
Lancet Global Health
The health-care system collapse underway in Venezuela is a cause of utmost concern for its people and, increasingly, for the wider region. Declines in provision of basic services, such as childhood immunisation, malaria control, water, sanitation, and nutritional support, have led to...

Is there a connection between gestational diabetes, human immunodeficiency virus infection, and tuberculosis?

Post Date: 
2019-01-01
   |   
Countries: 
   |   
Clinical Sites: 
Publication: 
International Journal of Tuberculosis and Lung Disease
IJTLD article reviews the epidemiology and immunology of gestational diabetes and finds there's a lot we don't know about interactions between diabetes, pregnancy, and tuberculosis in both HIV+/- women

Impact of providing preexposure prophylaxis for human immunodeficiency virus at clinics for sexually transmitted infections in Baltimore City: An agent-based model

Post Date: 
2018-12-15
   |   
Countries: 
Publication: 
Sexually Transmitted Diseases
BACKGROUND: Preexposure prophylaxis (PrEP) greatly reduces the risk of human immunodeficiency virus (HIV) acquisition, but its optimal delivery strategy remains uncertain. Clinics for sexually transmitted infections (STIs) can provide an efficient venue for PrEP delivery. ...

Pages

Drug Susceptibility of Rifampin-resistant Tuberculosis using Whole Genome Sequencing to Identify Genes of Interest in Pune, India

Post Date: 
2017-10-12
   |   
Clinical Sites: 
Tornheim JA , Madugundu AK, Pradhan N, Bharadwaj R, Mave V, Golub J, Pandey A, Gupta A. Drug Susceptibility of Rifampin-resistant Tuberculosis using Whole Genome Sequencing to Identify Genes of Interest in Pune, India. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico.

Biological Differences in Tuberculosis Diagnosis and Disease in Women

Post Date: 
2017-10-12
   |   
Clinical Sites: 
Mathad J. Biological Differences in Tuberculosis Diagnosis and Disease in Women. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico.

Symposium: From Bench to Bassinet: Scientific Innovations: The Fight against Maternal-Infant TB

Post Date: 
2017-10-12
   |   
Clinical Sites: 
Gupta A. Symposium: From Bench to Bassinet: Scientific Innovations: The Fight against Maternal-Infant TB. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico.

Linezolid Experience among MDRTB Patients in Mumbai

Post Date: 
2017-09-13
   |   
Countries: 
   |   
Clinical Sites: 
Tornheim J, Ganatra S, Deluca A, Banka R, Rodrigues C, Gupta A, Udwadia Z. Poster Presentation. Linezolid Experience among MDRTB Patients in Mumbai. ERS International Congress. European Respiratory Society. Milan, Italy.

Trends in Glycated Hemoglobin Levels and Implications for Diabetes Screening among Pulmonary Tuberculosis Cases Undergoing Treatment in India

Post Date: 
2017-09-13
   |   
Countries: 
   |   
Clinical Sites: 
Gupte AN , Mave V, Meshram S, Lokhande R, Kadam D, Dharmshale S, Bharadwaj R, Kagal A, Pradhan N, Deshmukh S, Atre S, Sahasrabudhe T, Barthwal M, Meshram S, Kakrani A, Kulkarni V, Raskar S, Suryavanshi S, Shivakoti R, Chon S, Selvin E, Gupte N, Gupta A, Golub JE. Trends in Glycated Hemoglobin...

High Burden of Diabetes and Prediabetes among Adult Household Contacts of India

Post Date: 
2017-09-13
   |   
Countries: 
   |   
Clinical Sites: 
Shivakumar SVBY , Chandrasekaran P, Kumar AJMV, Paradkar M, Dhanasekaran K, Suryavanshi N, Thomas B, Kohli R, Thiruvengadam K, Kulkarni V, Hannah LE, Sivaramakrishnan GN, Pradhan N, Dolla C, Gupte A, Ramachandran G, DeLuca A, Meshram S, Bhardawaj R, Bollinger RC, Golub J, Selvaraj K, Gupte N,...

Gene Expression Profiles of Pediatric Tuberculosis Patients and Exposed Controls from India

Post Date: 
2017-09-13
   |   
Countries: 
   |   
Clinical Sites: 
Tornheim JA , Paradkar M, Madugundu A, Gupte N, Kulkarni V, Sreenivasamurthy S, Raja R, Pradhan N, Shivakumar SVBY, Valvi C, Kohli R, Chandrasekaran P, Mave V, Pandey A, Gupta A. Gene Expression Profiles of Pediatric Tuberculosis Patients and Exposed Controls from India. RePORT International...

Hepatotoxicity in HIV+ Postpartum Women Initiating Efavirenz-Containing Regimens

Post Date: 
2017-07-26
   |   
Countries: 
Bhattacharya D , Gupta A, Tierney C, Huang S, Peters M, Chipato T, Martinson F, Dula D, George K, Chaktoura N, Klingman K, Gnanashanmugam D, Currier J, Fowler MG. Hepatotoxicity in HIV+ Postpartum Women Initiating Efavirenz-Containing Regimens. IAS 2017. International AIDS Society. Paris, France...

Hepatotoxicity in HIV+ Postpartum Women Initiating Efavirenz-Containing Regimens in PROMISE P1077

Post Date: 
2017-05-31
Amita Gupta. Hepatotoxicity in HIV+ Postpartum Women Initiating Efavirenz-Containing Regimens in PROMISE P1077. 2017 IMPAACT Annual Meeting. Washington, DC. 2017

A5300B/IMPAACT 2003B – PHOENix MDR TB: Protecting Households on Exposure to Newly Diagnosed Index Multidrug-Resistant TB Patients

Post Date: 
2017-05-30
Gupta, A. A5300B/IMPAACT 2003B – PHOENix MDR TB: Protecting Households on Exposure to Newly Diagnosed Index Multidrug-Resistant TB Patients. 2017 IMPAACT Annual Meeting. Washington, DC.

A5300/I2003/PHOENIx Trial Update

Post Date: 
2017-05-30
Gupta, A. A5300/I2003/PHOENIx Trial Update. 2017 IMPAACT Annual Meeting. Washington, DC. 2017.

IMPAACT 2001: Trial of the Pharmacokinetics, Tolerability, and Safety of Once-Weekly Rifapentine and Isoniazid in HIV-infected and HIV-1-uninfected Pregnant and Postpartum Women with Latent Tuberculosis Infection

Post Date: 
2017-05-30
Jyoti Mathad. IMPAACT 2001: Trial of the Pharmacokinetics, Tolerability, and Safety of Once-Weekly Rifapentine and Isoniazid in HIV-infected and HIV-1-uninfected Pregnant and Postpartum Women with Latent Tuberculosis Infection. 2017 IMPAACT Annual Meeting. Washington, DC. 2017.

CTRIUMPh Pediatric Biomarker Substudy

Post Date: 
2017-05-30
   |   
Countries: 
   |   
Clinical Sites: 
Tornheim J . Paradkar M. CTRIUMPh Pediatric Biomarker Substudy. 2017 IMPAACT Annual Meeting. Washington, DC. 2017.

A5300/I2003/PHOENIx Preparatory Study of MDR TB Cases and Their Household Contacts: Operational Feasibility to Inform PHOENIx Trial

Post Date: 
2017-05-29
   |   
Countries: 
   |   
Clinical Sites: 
Gupta, A. A5300/I2003/PHOENIx Preparatory Study of MDR TB Cases and Their Household Contacts: Operational Feasibility to Inform PHOENIx Trial. 2017 IMPAACT Annual Meeting. Washington, DC. 2017.

How Americans Benefit from Global Health Research

Post Date: 
2017-05-25
   |   
Countries: 
Bollinger, R. How Americans Benefit from Global Health Research. The Fogarty International Center: How Americans Benefit from Global Health Research Webinar, Research!America. Washington, DC.

Knowledge, Attitudes and Practices About Multidrug-Resistant Tuberculosis (MDR-TB) and Preventive Therapy Among Adult and Adolescent Household Contacts of MDR-TB Index Cases

Post Date: 
2017-05-22
   |   
Countries: 
   |   
Clinical Sites: 
Suryavanshi N, Shah S, Murrill M , Gupta A. Knowledge, Attitudes and Practices About Multidrug-Resistant Tuberculosis (MDR-TB) and Preventive Therapy Among Adult and Adolescent Household Contacts of MDR-TB Index Cases. American Thoracic Society 2017 International Conference. Washington, DC. 2017.

It Simply Won’t Work Here – Few Eligible for the Newly Recommended Short Course MDR-TB Regimen in a Mumbai Private Clinic

Post Date: 
2017-05-21
   |   
Countries: 
   |   
Clinical Sites: 
Tornheim J , DeLuca A, Ganatra S, Radhika B, Gupta A, Udwadia Z. It Simply Won’t Work Here – Few Eligible for the Newly Recommended Short Course MDR-TB Regimen in a Mumbai Private Clinic. American Thoracic Society 2017 International Conference. Washington, DC. 2017.

Communicating Whole Genome Sequencing Results for Tuberculosis: What Does It Mean and Who Needs to Know?

Post Date: 
2017-04-25
   |   
Countries: 
   |   
Clinical Sites: 
Tornheim, J. Communicating Whole Genome Sequencing Results for Tuberculosis: What Does It Mean and Who Needs to Know? Foundation for Medical Research. Mumbai, India.

What are We Trying to Say Here? Standardizing Next Generation Sequencing Reports for Tuberculosis

Post Date: 
2017-03-30
Tornheim, J. What are We Trying to Say Here? Standardizing Next Generation Sequencing Reports for Tuberculosis. 2017 Critical Path to TB Drug Regimens Annual Workshop. Washington, DC. 2017.

Validity of Reported Measures of Secondhand Smoke Exposure in Indian Households: Mishri Preparation a Potentially Overlooked Source in Low-Income Indian Communities

Post Date: 
2017-03-10
   |   
Clinical Sites: 
Elf JL , Kinikar AA, Khadse S, Mave V, Gupte N, Kulkarni V, Patekar S, Raichur P, Cohen J, Breysse PN, Gupta A, Golub JE. Validity of Reported Measures of Secondhand Smoke Exposure in Indian Households: Mishri Preparation a Potentially Overlooked Source in Low-Income Indian Communities. 23rd Annual...

Pages

4 ways that telemedicine can address the opioid crisis

Post Date: 
2017-12-01
Source: 
The Hill
CCGHE Director Dr. Bob Bollinger describes the utility of telemedicine in this opinion article in The Hill.

Combination HIV prevention reduces infections

Post Date: 
2017-12-01
Source: 
MD Magazine
. . . Researchers found that throughout the 7-year period in which rates of treatment and voluntary medical male circumcision increased significantly, HIV incidence dropped by 42% among nearly 18,000 people in Uganda . . .

Combination HIV Prevention Reduces New Infections by 42 Percent in Ugandan District

Post Date: 
2017-11-29
NIH announces findings from Larry Chang and colleagues published in the New England Journal of Medicine .

Male Circumcision and Antiviral Drugs Appear to Sharply Reduce HIV Infection Rate

Post Date: 
2017-11-29
. . . The study, published Nov. 29 in the New England Journal of Medicine , is the first to track a large group of people before, during and after the start of an HIV prevention program and show that the program is likely working on a large scale. The researchers found that as the program began and...

Male circumcision and antiviral drugs appear to sharply reduce HIV infection rate

Post Date: 
2017-11-29
Source: 
Medical Xpress
. . . The current study, based on RCCS data on 34,000 adults enrolled and followed between 1989 and 2016, confirmed the widespread adoption of many of PEPFAR's HIV prevention measures. The use of antiretroviral therapy among infected people rose steadily from 12 percent in the 2006 survey to 69...

Toward a TB-Free India

Post Date: 
2017-11-09
Source: 
Interagency TB Newsletter
TB research underway by the Indo-JHU clinical research partnership is highlighted in the US Interagency TB Newsletter.

Mexico conference: Experts from BJ Medical College make presentations on TB, treatment

Post Date: 
2017-11-09
Source: 
The Indian Express
Four fellows from the BJGMC-JHU Fogarty HIV-TB Training Program make national headlines in India.

CCGHE Joins 12-Country UNITAID Effort to Control TB

Post Date: 
2017-11-08
Shorter course to prevent progression of latent TB to active disease is the aim of the effort.

Efficacy maintained in HIV regimen switch

Post Date: 
2017-10-10
Source: 
MedPage Today
. . . "We still do have a lot of people on protease inhibitors in this country," Chida told MedPage Today. "Data to prove the safety and sustain viral load effect is important" to support decisions about switching. . .

CCGHE at the Union 2017

Post Date: 
2017-10-05
The 2017 Union Conference was in Guadalajaro, Mexico, October 11-14, and Indo-JHU research was well represented.

Tornheim Promoted to Assistant Professor

Post Date: 
2017-08-31
His research explores whether 2 MDR-TB drug susceptibility tests using WGS & MIC can yield options for individualized treament.

Reduced Level of Disease Possible in India by the Centennial

Post Date: 
2017-08-22
Source: 
India Abroad
India ranks highest in global disease burden. Dr. Amita Gupta weighs in on how to reverse that.

Indo-Hopkins Partnership Seeks Causes of Sepsis in the NICU

Post Date: 
2017-08-10
Sepsis among newborns in the neonatal intensive care unit (NICU) is a big problem in India, and a complex one to untangle.

How can we encourage female leaders in global health?

Post Date: 
2017-08-09
Source: 
Global Health Matters
Fogarty Director Dr. Roger Glass asks why so few women are leading global health centers at med schools or filling other leadership roles.

Sick and afraid, some immigrants forgo medical care

Post Date: 
2017-06-26
Source: 
The New York Times
Dr. Kathleen Page in the New York Times: US government deportation crackdown is affecting healthcare access among undocumented immigrants.

Company tests mobile health for tuberculosis treatment

Post Date: 
2017-05-23
Source: 
NIH: News and Events
Preliminary data show 93% treatment adherence using video observation, with savings of more than $1,000 per TB patient over 6 months

Fogarty International Center, a linchpin of global health research

Post Date: 
2017-05-17
Source: 
JAMA
Bob Bollinger weighs in on NIH’s Fogarty Program & the strategic benefits the program offers for US disease surveillance.

CCGHE at ATS 2017

Post Date: 
2017-05-08
Abstract presentations from the American Thoracic Society International Conference in Washington, DC

Health on the Go: Mobile Clinic Delivers TB Services at Point of Need

Post Date: 
2017-03-24
Thanks to Raj and Bharti Shah, CTIS, & the NB Shah Charitable Trust, we are able to reach more people in Maharashtra who need care

CROI 2017 Highlighted ACTG Network Presentations

Post Date: 
2017-02-28
Source: 
ACTG Newsletter
A5274: Impact of INH adherence on TB incidence and mortality by week 96 in REMEMBER Trial Amita Gupta, MD, MHS, Baltimore-Washington-India Clinical Trials Unit, co-PI and Investigator, Johns Hopkins University Clinical Research Site The A5274/REMEMBER trial team previously reported that among those...

Pages