Research News

Dr. Amita Gupta
February 27, 2020

In this Lancet Respiratory Medicine commentary, Dr. Amita Gupta and colleagues note that TB prevalence among children, adolescents, and women isn't well documented. This poses big challenges for the goal of TB elimination.

Clinical Research

Leadership
While we conduct research all over the world, the majority of our work is in India. Our Indo-JHU Clinical Research Partnership is located in Pune and is directed by Dr. Amita Gupta (Baltimore, MD), with onsite direction from Dr. Vidya Mave, Dr. Nishi Suryavanshi, and Dr. Nikhil Gupte (Pune). The Indo-JHU Partnership employs more than 200 people and in addition to our memberships in cosortia with many esteemed Indian research institutions, we have formal agreements with:

 
 

A Randomized Therapeutic Interventional Comparative Study between Three Different Modalities of Paediatric Antitubercular Treatment

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2016-06-13
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This study was terminated July 6, 2019. It was funded by the Fogarty International Center at the U.S. National Institutes of Health. This study evaluated three different TB treatment regimens in children attending Sassoon General Hospital in Pune, India. A convenience sample size of n=100 children...

Optimal Algorithmic Diagnosis of Genital TB among HIV-infected and Uninfected Infertile Women

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2016-05-26
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This study was terminated March 2020. It was funded by the Fogarty International Center at the U.S. National Institutes of Health. There is a lack of a set protocol universally for diagnosis of genital TB, and for Indian hospitals, India's Revised National Tuberculosis Control Program (RNTCP) also...

Whole Genome Sequencing and Trek Sensititre Testing of Stored Isolates of Drug-resistant Tuberculosis from a Clinical Cohort at Hinduja Hospital, Mumbai

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2016-05-02
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Among HIV-positive TB patients presenting to Médecins San Frontières (MSF) clinics in Mumbai, 78% carried MDR-TB strains, with nearly half also found to have additional drug resistance. A previously published cohort of 202 patients cared for at these MSF clinics have enrolled in a cross-sectional...

Comparison of Available Purified-protein Derivative (PPD) Tuberculin Skin Test (TST) Antigen Solutions in Detecting Latent Tuberculosis Infection in India

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2016-04-21
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This study is conducted by the Cohort for Tuberculosis Research by the Indo-US Medical Partnership (C-TRIUMPH) under the Regional Prospective Observational Research for Tuberculosis (RePORT) Network, an international TB consortium. Given the worldwide shortage of PPD TST antigen solutions, it is...

Barriers to Early Treatment Initiation in Childhood Tuberculosis in High Incidence Setting

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2016-04-21
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This study was terminated October 25, 2019. Funded by the Fogarty International Center and led by PI Dr. Chhaya Tukaram Valvi, the aim of this study is to evaluate the time to treatment initiation and barriers to early treatment initiation in childhood tuberculosis. TB diagnosis in children is...

Barriers to Implementation of Isoniazid Preventive Treatment (IPT) in Pediatric Contacts of Sputum Positive Adults with Tuberculosis

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2016-03-24
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This study was terminated January 3, 2019. It was funded by the Fogarty International Center at the U.S. National Institutes of Health. Young children infected with M.tuberculosis can rapidly progress to pulmonary and extrapulmonary disease with high rates of mortality and morbidity. Studies...

The Human Virome in Health and Disease

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2016-02-21
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This study is part of the Antimicrobial Resistance study referenced below, Some samples were used from the Cohort for Tuberculosis Research by the Indo-US Medical Partnership (C-TRIUMPH), under the Regional Prospective Observational Research for Tuberculosis (RePORT) Network, an international TB...

Whole Genome Sequencing of Clinical Isolates from Patients with Multidrug Resistant Tuberculosis in India 

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2015-11-12
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This study was terminated August 9, 2019. Comparative genomic analysis using whole genome sequencing (WGS) offers an opportunity to understand the specific mutations associated with drug resistance and the phenotypic behavior of TB. As treatment programs incorporate more molecular diagnostics such...

miDOT (Directly Observed Therapy)

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2015-11-01
Designed by Dr. Maunank Shah, the miDOT mobile health application is a video-based Directly Observed Therapy interface that uses the emocha Mobile Health platform to remotely connect patients on long-term tuberculosis therapy with clinicians who are required to witness patients taking...

Residual Respiratory Impairment Following Pulmonary Tuberculosis

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2015-09-13
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This study is conducted by the Cohort for Tuberculosis Research by the Indo-US Medical Partnership (C-TRIUMPH) under the Regional Prospective Observational Research for Tuberculosis (RePORT) Network, an international TB consortium. Many TB patients have...

A5300/IMPAACT2003: Study of MDR TB Cases and Their Household Contacts: Operational Feasibility to Inform PHOENIx Trial Design

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2015-09-01
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This clinical trial was terminated July 18, 2017. It was a study conducted under both the AIDS Clinical Trial Group (ACTG) and the the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Network, and funded by the U.S. National Institutes of Health. Dr. Amita Gupta was...

Prevalence Survey of Risk Factors for Tuberculosis and Non-communicable Diseases in an HIV-positive Population in Pune, India

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2015-08-17
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This study is conducted under the TREAT Asia Network and funded by amfAR. The primary objective of this study is to assess the prevalence of risk factors for tuberculosis and non-communicable diseases (NCDs)--coronary artery disease and diabetes mellitus--among HIV-positive patients. The study will...

A5290: A Randomized, Phase 2b Study of a Double-Dose Lopinavir/Ritonavir-Based Antiretroviral Regimen with Rifampin-Based Tuberculosis Treatment versus a Standard-Dose Lopinavir/Ritonavir-Based Antiretroviral Regimen with Rifabutin-Based Tuberculosis...

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2015-07-07
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This study was terminated February 23, 2016; it was conducted under the AIDS Clinical Trials Group (ACTG) and funded by the U.S. National Institutes of Health.. Full Title: A5290, A Randomized, Phase 2b Study of a Double-Dose Lopinavir/Ritonavir-Based Antiretroviral Regimen with Rifampin-Based...

Bacterial Antimicrobial Resistance Patterns in Pune, India: Substudy on Community Health-Seeking Behavior Among Patients Admitted with Acute Febrile Illness

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2015-05-28
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Objectives: To describe the patterns of health-care seeking behavior and prior outpatient care among patients admitted with acute febrile illness to Sassoon Hospital To determine the effects of outpatient behaviors and prior treatments on the antimicrobial resistance patterns of stool colonizing...

Barriers for Intervention to Prevent Occupationally Acquired Tuberculosis in Healthcare Workers

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2015-05-21
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This study was terminated April 20, 2017; it was funded by the Fogarty International Center at the U.S. National Institutes of Health. Observational study to assess the current status of implementation of interventions for preventing occupationally acquired TB in HCW. Identify the barriers to...

Risk of Tuberculosis among Health Care Workers and Trainees in a Tertiary-care Hospital in Pune, India

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2015-04-15
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This study was terminated April 24, 2018. It was funded by the Fogarty International Center at the U.S. National Institutes of Health. A retrospective study of health care workers (HCWs) was conducted by investigators of the Byramjee Jeejeebhoy Medical and Sassoon General Hospitals (BJMC-SGH) in...

Community Health Workers, mHealth, and Combination HIV Prevention in a Hotspot: A Randomized Trial (mLAKE)

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2015-04-01
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Led by Dr. Larry Chang, the mLAKE study in Uganda is examining whether community health workers equipped with cellphones and the emocha Mobile Health platform are able to successfully promote HIV treatment and prevention services in households in a fishing community in East Africa with a very high...

Enhancing Models of HIV, Viral Hepatitis, STIs and Tuberculosis to Inform and Improve Public Health Impact

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2015-01-01
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This study was terminated September 30, 2018. Dr. Maunank Shah was the Project Leader for HIV modeling for this effort led by Emory University and funded by the U.S. Centers for Disease Control and Prevention.

Salud al Dia

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2014-11-01
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This initiative is intended to address healthcare disparities among Latino children in Baltimore by increasing engagement of limited English proficiency (LEP) Latino parents in primary healthcare. Specifically, we are looking at whether using in-person and technology-based support interventions...

Inflammation in HIV-infected Pregnant Women: Relationship with Diet, Gut Microbiome and Preterm Birth

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2014-10-28
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This study was terminated May 7, 2018. P regnancy is a state of relative immunosuppression in order to protect the fetus from being rejected. It has also been shown that the Th-1 helper cell response, which is normally necessary for overcoming TB infection, is suppressed in pregnancy. Thus,...

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Identifying solutions to improve the sexually transmitted infections testing experience for youth through participatory ideation

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2018-08-15
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AIDS Patient Care and STDs
Sexually transmitted infection (STI) services, including screening, treatment, and counseling among youth, remain suboptimal. In the midst of increasing incidence of bacterial STIs, alarming STI disparities, and persistently low testing rates among youth, solution-focused and action-oriented...

Challenges of TB and co-treatment: updates and insights

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2018-08-04
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Current Opinion in HIV and AIDS
PURPOSE OF REVIEW: In the past few years, tuberculosis (TB) has overtaken HIV as the infectious disease with the highest global mortality. Successful management of this syndemic will require improved diagnostic tests, shorter preventive therapies, and more effective treatments,...

Tuberculin skin test and QuantiFERON-Gold In Tube assay for diagnosis of latent TB infection among household contacts of pulmonary TB patients in high TB burden setting

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2018-08-01
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PLoS One
World Health Organization (WHO) recommends systematic screening of high-risk populations, including household contacts (HHCs) of adult pulmonary tuberculosis (TB) patients, as a key strategy for elimination of TB. QuantiFERON-TB Gold In-Tube (QFT-GIT) assay and tuberculin skin test (TST) are two commonly used tools for the detection of latent tuberculosis infection (LTBI) but may yield differential results, affecting eligibility for TB preventive therapy.

Using mHealth to improve tuberculosis case identification and treatment initiation in South Africa: Results from a pilot study

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2018-07-03
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PLoS One
BACKGROUND: Tuberculosis (TB) incidence in South Africa is among the highest globally. Initial loss to follow-up (ILFU), defined as not starting on TB treatment within 28 days of testing positive, is undermining control efforts. We assessed the feasibility, acceptability, and potential...

Trends in HbA1c levels and implications for diabetes screening in tuberculosis cases undergoing treatment in India

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2018-07-01
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International Journal of Tuberculosis and Lung Disease
SETTING: The optimal timing of screening for diabetes mellitus (DM) among tuberculosis (TB) cases is unclear due to the possibility of stress hyperglycemia. DESIGN: We evaluated adult (18 years) pulmonary TB cases at treatment initiation as well as at 3 months,...

Internal medicine residents' knowledge and practice of pulmonary tuberculosis diagnosis

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2018-06-27
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Open Forum Infectious Diseases
BACKGROUND: Internal medicine physicians are often the first providers to encounter patients with a new diagnosis of tuberculosis. Given the public health risks of missed tuberculosis cases, assessing internal medicine residents' ability to diagnose tuberculosis is important. ...

Loss to follow‐up and mortality among HIV‐infected adolescents receiving antiretroviral therapy in Pune, India

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2018-06-25
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HIV Medicine
Over 6 years, one-third of HIV+ adolescents in this study discontinued medical treatment, indicating a critical need for retention counselling and closer clinical monitoring.

Effect of baseline micronutrient and inflammation status on CD4 recovery post-cART initiation in the multinational PEARLS trial

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2018-05-29
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Clinical Nutrition
Nutritional deficiency and inflammation may impact CD4+ T cell recovery during combination antiretroviral therapy (cART), particularly in resource-limited settings where malnutrition is prevalent. The aim of this study was to investigate the relationship of micronutrient and inflammation biomarkers to CD4 recovery after cART initiation.

Sources of household air pollution and their association with fine particulate matter in low-income urban homes in India

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2018-05-23
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Journal of Exposure Science and Environmental Epidemiology
INTRODUCTION: Household air pollution (HAP) is poorly characterized in low-income urban Indian communities. MATERIALS AND METHODS: A questionnaire assessing sources of HAP and 24 h household concentrations of particulate matter less than 2.5 microns in diameter (...

The global neurological burden of tuberculosis

Post Date: 
2018-05-18
Publication: 
Seminars in Neurology
Central nervous system (CNS) involvement of tuberculosis (TB) is the most severe manifestation of TB and accounts for approximately 5 to 10% of all extrapulmonary TB (EPTB) cases and approximately 1% of all TB cases. TB meningitis (TBM) is the most common form of CNS TB, though other forms...

Group mentorship model to enhance the efficiency and productivity of PhD research training in Sub-Saharan Africa

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2018-05-04
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Annals of Global Health
Annals of Global Health : Systems capacity building approach to PhD training allowed strong outputs at lower cost and with relatively few additional mentors to train independent scientists able to conduct original research and mentor others.

Antibiotic utilization and the role of suspected and diagnosed mosquito borne illness among adults and children with acute febrile illness in Pune, India

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2018-05-02
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Clinical Infectious Diseases
Mosquito-borne disease identification is associated with reduced empiric antibiotic use and faster antibiotic discontinuation.

Addressing knowledge gaps and prevention for tuberculosis-infected Indian adults: a vital part of elimination

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2018-05-02
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BMC Infectious Diseases
BMC Infectious Diseases : Our survey among TB patients' household contacts with evidence of recent exposure found that knowledge is poor and families are confused about disease transmission.

Hepatotoxicity during isoniazid preventive therapy and antiretroviral therapy in people living with HIV with severe immunosuppression: a secondary analysis of a multi-country open-label randomized controlled clinical trial

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2018-05-01
Publication: 
Journal of Acquired Immune Deficiency Syndromes
BACKGROUND: Hepatotoxicity associated with isoniazid preventive therapy (IPT) and antiretroviral therapy (ART) has not been well studied in severely immunosuppressed people with HIV. Our objective was to determine risk factors for hepatotoxicity in severely immunosuppressed individuals...

MDR-TB in children: back to the basics

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2018-05-01
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The International Journal of Tuberculosis and Lung Disease
IJTLD: Summary of the Pediatric Multidrug-Resistant Tuberculosis Clinical Trials Landscape Meeting: a primer of current directions.

Advancing patient-centered care in tuberculosis management: A mixed-methods appraisal of video directly observed therapy

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2018-04-26
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Open Forum Infectious Diseases
BACKGROUND: Directly observed therapy (DOT) remains an integral component of treatment support and adherence monitoring in tuberculosis care. In-person DOT is resource intensive and often burdensome for patients. Video DOT (vDOT) has been proposed as an alternative to increase treatment...

Shorter treatment for minimal tuberculosis (TB) in children (SHINE): a study protocol for a randomised controlled trial

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2018-04-19
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Trials
Trials: Evidence for TB treatment in kids is largely based on adult studies. The SHINE study aims to fix this

Migration and risk of HIV acquisition in Rakai, Uganda: a population-based cohort study

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2018-04-15
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Lancet HIV
BACKGROUND: In sub-Saharan Africa, migrants typically have higher HIV prevalence than non-migrants; however, whether HIV acquisition typically precedes or follows migration is unknown. We aimed to investigate the risk of HIV after migration in Rakai District, Uganda. ...

Prevention of HIV-1 transmission through breastfeeding:efficacy of safety of maternal antiretroviral therapy versus infant nevirapine prophylaxis for duration of breastfeeding in HIV-1-infected women with high CD4 cell count (IMPAACT PROMISE)

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2018-04-01
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Journal of Acquired Immune Deficiency Syndromes
BACKGROUND: No randomized trial has directly compared the efficacy of prolonged infant antiretroviral prophylaxis versus maternal antiretroviral therapy (mART) for prevention of mother-to-child transmission throughout the breastfeeding period. SETTING: Fourteen...

HIV viral suppression and geospatial patterns of HIV antiretroviral therapy treatment facility use in Rakai, Uganda

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2018-03-27
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AIDS
OBJECTIVE: To assess geospatial patterns of HIV antiretroviral therapy (ART) treatment facility use and whether they were impacted by viral load suppression. METHODS: We extracted data on the location and type of care services utilized by HIV-positive persons...

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A5300B/IMPAACT 2003B – PHOENix MDR TB: Protecting Households on Exposure to Newly Diagnosed Index Multidrug-Resistant TB Patients

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2017-05-30
Gupta, A. A5300B/IMPAACT 2003B – PHOENix MDR TB: Protecting Households on Exposure to Newly Diagnosed Index Multidrug-Resistant TB Patients. 2017 IMPAACT Annual Meeting. Washington, DC.

A5300/I2003/PHOENIx Trial Update

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2017-05-30
Gupta, A. A5300/I2003/PHOENIx Trial Update. 2017 IMPAACT Annual Meeting. Washington, DC. 2017.

IMPAACT 2001: Trial of the Pharmacokinetics, Tolerability, and Safety of Once-Weekly Rifapentine and Isoniazid in HIV-infected and HIV-1-uninfected Pregnant and Postpartum Women with Latent Tuberculosis Infection

Post Date: 
2017-05-30
Jyoti Mathad. IMPAACT 2001: Trial of the Pharmacokinetics, Tolerability, and Safety of Once-Weekly Rifapentine and Isoniazid in HIV-infected and HIV-1-uninfected Pregnant and Postpartum Women with Latent Tuberculosis Infection. 2017 IMPAACT Annual Meeting. Washington, DC. 2017.

CTRIUMPh Pediatric Biomarker Substudy

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2017-05-30
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Tornheim J . Paradkar M. CTRIUMPh Pediatric Biomarker Substudy. 2017 IMPAACT Annual Meeting. Washington, DC. 2017.

A5300/I2003/PHOENIx Preparatory Study of MDR TB Cases and Their Household Contacts: Operational Feasibility to Inform PHOENIx Trial

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2017-05-29
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Gupta, A. A5300/I2003/PHOENIx Preparatory Study of MDR TB Cases and Their Household Contacts: Operational Feasibility to Inform PHOENIx Trial. 2017 IMPAACT Annual Meeting. Washington, DC. 2017.

How Americans Benefit from Global Health Research

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2017-05-25
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Bollinger, R. How Americans Benefit from Global Health Research. The Fogarty International Center: How Americans Benefit from Global Health Research Webinar, Research!America. Washington, DC.

Knowledge, Attitudes and Practices About Multidrug-Resistant Tuberculosis (MDR-TB) and Preventive Therapy Among Adult and Adolescent Household Contacts of MDR-TB Index Cases

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2017-05-22
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Suryavanshi N, Shah S, Murrill M , Gupta A. Knowledge, Attitudes and Practices About Multidrug-Resistant Tuberculosis (MDR-TB) and Preventive Therapy Among Adult and Adolescent Household Contacts of MDR-TB Index Cases. American Thoracic Society 2017 International Conference. Washington, DC. 2017.

It Simply Won’t Work Here – Few Eligible for the Newly Recommended Short Course MDR-TB Regimen in a Mumbai Private Clinic

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2017-05-21
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Tornheim J , DeLuca A, Ganatra S, Radhika B, Gupta A, Udwadia Z. It Simply Won’t Work Here – Few Eligible for the Newly Recommended Short Course MDR-TB Regimen in a Mumbai Private Clinic. American Thoracic Society 2017 International Conference. Washington, DC. 2017.

Communicating Whole Genome Sequencing Results for Tuberculosis: What Does It Mean and Who Needs to Know?

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2017-04-25
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Tornheim, J. Communicating Whole Genome Sequencing Results for Tuberculosis: What Does It Mean and Who Needs to Know? Foundation for Medical Research. Mumbai, India.

What are We Trying to Say Here? Standardizing Next Generation Sequencing Reports for Tuberculosis

Post Date: 
2017-03-30
Tornheim, J. What are We Trying to Say Here? Standardizing Next Generation Sequencing Reports for Tuberculosis. 2017 Critical Path to TB Drug Regimens Annual Workshop. Washington, DC. 2017.

Validity of Reported Measures of Secondhand Smoke Exposure in Indian Households: Mishri Preparation a Potentially Overlooked Source in Low-Income Indian Communities

Post Date: 
2017-03-10
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Elf JL , Kinikar AA, Khadse S, Mave V, Gupte N, Kulkarni V, Patekar S, Raichur P, Cohen J, Breysse PN, Gupta A, Golub JE. Validity of Reported Measures of Secondhand Smoke Exposure in Indian Households: Mishri Preparation a Potentially Overlooked Source in Low-Income Indian Communities. 23rd Annual...

mHealth in medicine: A Hopkins-Focused Perspective

Post Date: 
2017-02-24
Chang, L. mHealth in medicine: A Hopkins-Focused Perspective. Digital Health Day. Johns Hopkins University. Baltimore, MD.

HIV Testing Uptake Among Household Contacts of MDR-TB Index Cases in Eight Countries

Post Date: 
2017-02-14
Opollo VS, Wu X, Lando R, Swindells S, Gupta A, Hesseling A, Dawson R, Hughes MD, Shah S. HIV Testing Uptake Among Household Contacts of MDR-TB Index Cases in Eight Countries. CROI 2017. Seattle, Washington. 2017.

Impact of INH Adherence on TB Incidence and Mortality by Week 96 in ACTG 5274 Trial 

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2017-02-14
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Gupta A , Sun X, Miyahara S, Matoga M, Langat D, Riviere C, Bisson C, Kumwenda J, Hosseinipour MC, for the ACTG A5274/REMEMBER Study Team. Impact of INH Adherence on TB Incidence and Mortality by Week 96 in ACTG 5274 Trial. CROI 2017. Seattle, Washington. 2017.

Inflammation Biomarkers Predict Clinical Treatment Failure in HIV-infected Adults

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2017-02-14
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Shivakoti R , Gupte N, Pillay S, Riviere C, Cardoso SW, Balagopal A, Semba R, Campbell T, Gupta A. Inflammation Biomarkers Predict Clinical Treatment Failure in HIV-infected Adults. CROI 2017. Seattle, Washington. 2017.

Risk Factors for Death in Advanced HIV-Infected Adults in an Empiric TB Therapy Trial

Post Date: 
2017-02-14
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Bisson G, Ramchandani R , Miyahara S, Sun X, Bao J, Gupta A, Hosseinipour MC, Kumwenda J. Risk Factors for Death in Advanced HIV-Infected Adults in an Empiric TB Therapy Trial. CROI 2017. Seattle, Washington. 2017.

Hepatotoxicity in People with Advanced Immunosuppression taking Isoniazid Preventive Therapy and Antiretroviral Therapy

Post Date: 
2017-02-14
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Ngongondo M , Miyahara S, Hughes MD, Sun X, Gupta A, Kumwenda J, Torres TS, Bisson G, Hosseinipour MC. Hepatotoxicity in People with Advanced Immunosuppression taking Isoniazid Preventive Therapy and Antiretroviral Therapy. CROI 2017. Seattle, Washington. 2017.

Factors Associated with Pulmonary Impairment in HIV-infected South African Adults

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2017-02-14
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Gupte A , Wong M, Msandiwa R, Barnes G, Golub J, Chaisson R, Hoffmann C, Martinson N. Factors Associated with Pulmonary Impairment in HIV-infected South African Adults. CROI 2017. Seattle, Washington. 2017.

Household Contact Tracing of Adult Pulmonary TB Patients in India: Prevalence of TB Disease and Infection

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2017-02-03
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Chandrasekaran P , Thiruvengadam K, Gupte N, Luck EH, Mave M, Gupte A, Gupta A, Swaminathan S. Household Contact Tracing of Adult Pulmonary TB Patients in India: Prevalence of TB Disease and Infection. 6th Annual Regional Prospective Observational Research for Tuberculosis (RePORT) India Joint...

Impact of Drug Susceptibility Testing on Drug Choice in a Tuberculosis Cohort with High Rates of Drug Resistance from the Private Sector in Mumbai

Post Date: 
2017-02-03
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Tornheim JA , Ganatra S, DeLuca A, Banka R, Gupta A, Udwadia ZF. Impact of Drug Susceptibility Testing on Drug Choice in a Tuberculosis Cohort with High Rates of Drug Resistance from the Private Sector in Mumbai. 6th Annual Regional Prospective Observational Research for Tuberculosis (RePORT) India...

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World AIDS Day 2016 at BJGMC

Post Date: 
2016-12-06
Read more about 2016 World AIDS Day activities at the BJGMC Clinical Site in Pune, India.

CCGHE at ID Week 2016

Post Date: 
2016-10-11
OCTOBER 27 TB Infection Prevalence, Incidence and Risk Factors among Child and Adult Household Contacts of Adult TB Cases in India Shivakumar SVBY, Chandrasekaran P, Thiruvengadam K, Gupte N, Mave V, Hannah LE, Kulkarni V, Gupte A, Deluca A, Gomathy NS, Sathyamurthi P, Paradkar M, Kohli R, Meshram...

Imec’s miDiagnostics joint venture does blood tests from blood-drop

Post Date: 
2016-08-09
Source: 
Electronics Weekly
miDiagnostics, the joint venture between Imec and Johns Hopkins University, aims to develop IC-based diagnostic tests which use drops of blood to detect cells, proteins, nucleic acids, and/or small molecules.

emocha’s public health apps are heading to California

Post Date: 
2016-08-02
Source: 
Technical.ly Baltimore
Three counties in California signed on to use emocha’s apps for managing tuberculosis. The Johns Hopkins spinout is implementing miDOT in Fresno, Merced and Contra Costa counties.

Emocha brings TB adherence tech to California as part of national expansion

Post Date: 
2016-08-02
Source: 
MedCity News
Emocha, a digital health startup seeking to create more flexibility for tuberculosis patients to meet the requirements for Directly Observed Therapy, or DOT, has added a new set of customers in California as part of a national expansion.

Help on wheels to screen TB in rural areas

Post Date: 
2016-07-26
Source: 
The Times of India
A state-of the art health services bus would provide medical care to rural populace at their doorsteps. Designed through a donation of US$100,000 from philanthropists Raj and Bharati Shah of the US-based Capital Technology Information Services (CTIS), the mobile health and wellness clinic launched...

Mobile Health and Wellness Clinic Debuts in Pune for Clinical Research and Community-Based Care

Post Date: 
2016-07-25
The Maryland-based health care informatics company CTIS and its founders, Raj and Bharti Shah, have collaborated with the Johns Hopkins Center for Clinical Global Health Education and Byramjee Jeejeebhoy Government Medical College to equip and dispatch a custom-designed mobile health care services...

CCGHE at AIDS 2016

Post Date: 
2016-07-20
CCGHE efforts presented at AIDS 2016 in Durban, South Africa

2016 Global Health Established Field Placement Awardees

Post Date: 
2016-06-28
The following Johns Hopkins students received Global Health Established Field Placement Awards to work on CCGHE research studies in India and Uganda. Each student is spending a minimum of 6 weeks in the field, and each has been awarded $3500 from the Johns Hopkins Center for Global Health for...

Confronting Gender Based Violence 2016 Course

Post Date: 
2016-06-16
2016-06-16—The Johns Hopkins Center for Clinical Global Health Education (CCGHE) is pleased to launch the free online course Confronting Gender-based Violence: Global Lessons for Healthcare Workers. Registration is now open for the course, which is being offered through Coursera. It is scheduled to...

Up Close: Jessica Elf

Post Date: 
2016-05-31
The quality of air is an ethical imperative.

Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in HIV-positive adults

Post Date: 
2016-05-11
Source: 
Science Daily
An international review team has prepared a systematic review to assess the accuracy of a point-of-care urine test for diagnosing and screening tuberculosis (TB) in people living with human immunodeficiency virus (HIV).

Amita Gupta Appointed US Chair for India TB Research Consortium

Post Date: 
2016-05-11
“After more than 40 years of little discovery, interest, or funding for TB research, we are at a nexus of advancement."

Can Technology & Training Promote Retention in Care & Prevent HIV Transmission?

Post Date: 
2016-05-10
When HIV+ mothers are actively engaged in care, they are far less likely to transmit the disease to their babies. And while HIV+ women in India generally seek initial care, maintaining continuity of care can be challenging. One study in India seeks to answer the question: Can a focused...

Mobile Technology Developed at Hopkins Medicine Transforming TB Care in Texas

Post Date: 
2016-04-19
Harris County Public Health Environmental Services Hailed TB Elimination Champion by CDC The US Centers for Disease Control and Prevention recently named Harris County Public Health Environmental Services among its 2016 TB Elimination Champions for...

Study evaluates four-drug TB treatment for HIV/AIDS patients

Post Date: 
2016-04-04
Source: 
Vaccine News Daily
"Our results even suggest the four-drug strategy is actually doing more harm than isoniazid-alone therapy because study participants found it less tolerable and stopped using it," Dr. Amita Gupta, senior study author and associate professor of medicine and deputy director of the Johns Hopkins...

Feasibility Study Complete on Preventive Therapy for Household Contacts of MDR-TB Patients in Pune, India

Post Date: 
2016-03-31
March 31, 2016—Pune, India—The Baltimore-Washington-India Clinical Trials Unit is pleased to announce that the BJGMC Clinical Research Site (BJGMC-CRS) in Pune, India, just finished the feasibility study titled A5300/IMPAACT2003: Study of MDR-TB Cases and their Household Contacts: Operational...

In Many Regions, World Tuberculosis Day is Every Day

Post Date: 
2016-03-24
India Assumes the Greatest Burden Each year on March 24, the world pauses to reflect on the devastation that tuberculosis causes globally. TB is preventable and treatable, and it disproportionately and gravely affects resource-limited regions of the world. The World Health Organization reports that...

Proactively treating HIV patients at risk for tuberculosis with multi-drug TB regimens doesn't save more lives

Post Date: 
2016-03-20
Source: 
Health Canal
The number one killer of HIV patients in resource-limited areas, including parts of Africa and India, is tuberculosis (TB), underscoring the need for optimal treatments and effective strategies to address this deadly co-infection. But TB is harder to detect in HIV-infected patients and diagnostic...

Proactively treating HIV patients at risk for tuberculosis with multi-drug TB regimens doesn't save more lives

Post Date: 
2016-03-18
Source: 
Infection Control Today
In what investigators say is a surprise finding, results of a new study appear to strongly affirm the effectiveness of prescribing the anti-tuberculosis drug isoniazid alone — in place of the standard four-drug regimen — to prevent TB and reduce death in

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