Research News

ClinInf

We assessed multidrug-resistant tuberculosis (MDR-TB) cases and their household contacts (HHCs) to inform the development of an interventional clinical trial.

Tuberculosis, Gestational Diabetes, and HIV graphic

IJTLD article reviews the epidemiology and immunology of gestational diabetes and finds there's a lot we don't know about interactions between diabetes, pregnancy, and tuberculosis in both HIV+/- women

Clinical Research

Leadership
Dr. Amita Gupta of Johns Hopkins is Principal Investigator for the Indo-JHU Clinical Research Partnership based out of CCGHE. Research is directed locally in India out of the BJGMC-JHU Clinical Research Site by Dr. Vidya Mave, a Hopkins faculty member who lives in Pune. Dr. Nikhil Gupte is the Lead Biostatistician and Deputy Director and Dr. Nishi Suryavanshi is Clinical Site Coordinator and Deputy Director. Research is conducted in collaboration with the following institutions:
 
 

Risk of Tuberculosis among Health Care Workers and Trainees in a Tertiary-care Hospital in Pune, India

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2015-04-15
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This study was funded by the Fogarty International Center at the U.S. National Institutes of Health. A retrospective study of health care workers (HCWs) was conducted by investigators of the Byramjee Jeejeebhoy Medical and Sassoon General Hospitals (BJMC-SGH) in Pune, India. The purpose of the...

Community Health Workers, mHealth, and Combination HIV Prevention in a Hotspot: A Randomized Trial (mLAKE)

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2015-04-01
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Led by Dr. Larry Chang, the mLAKE study in Uganda is examining whether community health workers equipped with cellphones and the emocha Mobile Health platform are able to successfully promote HIV treatment and prevention services in households in a fishing community in East Africa with a very high...

Enhancing Models of HIV, Viral Hepatitis, STIs and Tuberculosis to Inform and Improve Public Health Impact

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2015-01-01
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This study was terminated September 30, 2018. Dr. Maunank Shah was the Project Leader for HIV modeling for this effort led by Emory University and funded by the U.S. Centers for Disease Control and Prevention.

Salud al Dia

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2014-11-01
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This initiative is intended to address healthcare disparities among Latino children in Baltimore by increasing engagement of limited English proficiency (LEP) Latino parents in primary healthcare. Specifically, we are looking at whether using in-person and technology-based support interventions...

Predictive Value of TB-symptom Screen in HIV-infected and HIV-uninfected Pregnant Women in Pune, India

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2014-10-28
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This study is terminated. This is a cross sectional observational study will be conducted at BJGMC to establish what the predictive value of the WHO TB symptom screen is in pregnant women in India. We hypothesize that the WHO TB symptom screen will have a higher positive predictive value (PPV) in...

Inflammation in HIV-infected Pregnant Women: Relationship with Diet, Gut Microbiome and Preterm Birth

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2014-10-28
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This study was terminated May 7, 2018. P regnancy is a state of relative immunosuppression in order to protect the fetus from being rejected. It has also been shown that the Th-1 helper cell response, which is normally necessary for overcoming TB infection, is suppressed in pregnancy. Thus,...

miLINC: MDR-TB South Africa - Patient Linkage to and Retention in Care

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2014-10-06
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Mycobacterium tuberculosis (TB) remains the leading cause of death among persons living with human immunodeficiency virus and acquired immunodeficiency syndrome (HIV/AIDS) in southern Africa. Drug-resistant TB remains a growing threat to public health despite advances made in diagnosis and...

Project S.O.A.R. (Supporting Operational AIDS Research): Positive Health Dignity and Prevention Sub-Project

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2014-09-15
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Dr. Larry Chang is a Co-Investigator for this effort. Purpose The goal of Project SOAR (Supporting Operational AIDS Research) is to improve the quality and impact of HIV and AIDS program outcomes by strengthening operations research and evaluation activities. Project SOAR supports the PEPFAR...

TBM Kids Substudy: Assessment of Neurocognitive Functions in Children with Tuberculosis Meningitis and Healthy Control Children Using the Mullen Scale of Early Learning Attending a Tertiary Care Public Hospital in Pune, India

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2014-09-01
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Objectives: The aim of the present study is to examine the neurological deficit in TBM kids and for that we need to assess, feasibility of the MSEL in our set up an Indian population of healthy children and children with meningitis in particular TB meningitis(TBM). The primary objective of the...

Impact of Immune Changes of HIV and Stages of Pregnancy on Tuberculosis

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2014-09-01
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This is the Parent Study for CCGHE’s PRACHITI (PRegnancy And CHanges In TuberculosIs) effort. It's supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development at the U.S. National Institutes of Health. Purpose: TB is a leading cause of maternal mortality,...

Diagnosis of Tuberculosis Infection and Th1 Immune Response in Pregnant Women in India

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2014-09-01
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This study was terminated April 16, 2018. Tuberculosis (TB) disease is a major cause of mortality among Indian women of reproductive age; approximately 20-50% of women in India are latently infected with Mycobacterium tuberculosis (MTB). Due to immune changes of pregnancy, women are particularly at...

Evaluating Demand Generation (Stylish Man) for HIV/Family Planning Services, Rakai, Uganda

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2014-08-01
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Dr. Larry Chang is co-investigator of this effort to test a novel approach to promoting HIV services in Rakai, Uganda. The Stylish Man Program, attempts to “demedicalize” HIV prevention and care in a public health campaign designed to normalize HIV care as part of self care for African men. The...

A5279: Phase III Clinical Trial of Ultra-Short-Course Rifapentine/Isoniazid for the Prevention of Active Tuberculosis in HIV-infected Individuals with Latent Tuberculosis Infection

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2014-06-30
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This study ended April 27, 2015; it was conducted under the AIDS Clinical Trials Group (ACTG) and funded by the U.S. National Institutes of Health. Dr. Amita Gupta was Protocol Co-Vice Chair for this multinational clinical trial being conducted in Botswana, Brazil, Haiti, Kenya, Malawi, Peru,...

Optimizing Treatment to Improve TBM Outcomes in Children

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2014-05-01
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This study, known as TBM Kids, is being conducted in India and Malawi. Primary Objectives To characterize the pharmacokinetics (PK) (plasma and cerebrospinal fluid (CSF)) of rifampicin given at model-derived optimal daily doses and levofloxacin in children ages 6 months to 12 years of age with TBM...

P1078: A Phase IV Randomized Double-Blind Placebo-Controlled Trial to Evaluate the Safety of Immediate (Antepartum-Initiated) Versus Deferred (Postpartum-Initiated) Isoniazid Preventive Therapy Among HIV-Infected Women in High TB Incidence Settings

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2014-04-01
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This is a clinical trial conducted under the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Network and funded by the U.S. National Institutes of Health. Dr. Amita Gupta is Protocol Chair for this multinational clinical trial being conducted in Botswana, Haiti, South...

Pulmonary and Functional Status of Patients with Pulmonary Mycobacterium Tuberculosis Post-treatment in Lima, Peru

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2014-01-01
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To conduct a longitudinal study evaluating the hypothesis that pulmonary function and functional status (functional capacity and quality of life) is reduced among individuals previously treated for pulmonary tuberculosis compared to those without a history of tuberculosis.

Evaluation of HIV Disease Burden in Hospitalized Patients at Sassoon General Hospital in Pune, India

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2013-11-18
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This study was terminated September 13, 2005. The goal of this project was to conduct both a retrospective and prospective epidemiological study of the burden of HIV disease at Sassoon General Hospital. The specific objectives of the study were to establish the proportion of HIV-infected...

Tuberculosis Noon Conference

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2013-10-24
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This effort ended in 2015. As part of the BJGMC-Johns Hopkins India Fogarty Training Program, from 2013-2015 CCGHE hosted the live Tuberculosis Noon Conference webcast. Led by Drs. Maunank Shah, Jonathan Golub, and Richard Chaisson, these webcast meetings brought together Johns Hopkins TB...

Cohort for Tuberculosis Research by the Indo-US Medical Partnership (C-TRIUMPH)

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2013-09-28
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Collaboratively funded by the US NIH, India’s Department of Biotechnology [DBT], and Indian Council of Medical Research, the Cohort for TB Research by the Indo-US Medical Partnership (C-TRIUMPH) is an Indo-US research consortium that is part of RePORT India, a countrywide consortium for TB research...

Assessing the Association of Indoor Air Pollution with Tuberculosis in Adult Women and Children under 5 Years of Age

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2013-09-15
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This study is conducted the Cohort for Tuberculosis Research by the Indo-US Medical Partnership (C-TRIUMPH) under the Regional Prospective Observational Research for Tuberculosis (RePORT) Network, an international TB consortium. Addressing social and environmental risk factors contributing to TB...

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Cardiovascular risk in an HIV-infected population in India

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2017-07-03
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Heart Asia
Findings: HIV+ Indian patients who had cardiovascular disease at a younger age appear to be at imminent risk for morbidity.

A qualitative study exploring factors influencing clinical decision-making for influenza-like illness in Solapur city, Maharashtra, India

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2017-07-03
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Anthropology and Medicine
Abstract The co-existence of different types of medical systems (medical pluralism) is a typical feature of India's healthcare system. For conditions such as influenza-like illness (ILI), where non-specific disease signs/symptoms exist, clinical reasoning in the context of medical pluralism becomes...

Household food insecurity is associated with low interferon-gamma levels in pregnant Indian women

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2017-07-01
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International Journal of Tuberculosis and Lung Disease
Objective: To determine the association between household food insecurity and interferon-gamma (IFN-γ) levels in pregnancy. Design: Pregnant women in India were administered the Household Food Insecurity Access Scale (HFIAS) questionnaire and underwent an IFN-γ release assay. Logistic regression...

Vitamin A and D deficiencies associated with incident tuberculosis in HIV-infected patients initiating antiretroviral therapy in multinational case-cohort study

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2017-07-01
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Journal of Acquired Immune Deficiency Syndromes
Introduction: Numerous micronutrients have immunomodulatory roles that may influence risk of tuberculosis (TB), but the association between baseline micronutrient deficiencies and incident TB after antiretroviral therapy (ART) initiation in HIV-infected individuals is not well characterized...

Maternal syphilis: An independent risk factor for mother to infant human immunodeficiency virus transmission

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2017-06-15
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Sexually Transmitted Diseases
Abstract Syphilis is associated with increased human immunodeficiency virus acquisition and sexual transmission; we examined impact on human immunodeficiency virus mother-to-child transmission among mother-infant pairs enrolled in the India Six-Week Extended-Dose Nevirapine study. Maternal syphilis...

Presence of human hepegivirus-1 in a cohort of people who inject drugs

Post Date: 
2017-06-07
Publication: 
Annals of Internal Medicine
Findings on the sensitivity of next-generation metagenomic sequencing for discovery of new viral infections.

Tuberculosis screening among persons with diabetes mellitus in Pune, India

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2017-06-02
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BMC Infectious Diseases
Background: Diabetes mellitus (DM) increases tuberculosis (TB) risk, and there is increasing concern over the public health implications of the convergence of these two epidemics. Screening for TB among people with DM is now recommended in India. Methods: People with DM seeking care at a large...

Pulmonary infections in pregnancy

Post Date: 
2017-06-01
Publication: 
Seminars in Respiratory and Critical Care Medicine
Clinical review from Drs. Amita Gupta & Jyoti Mathad on improving tuberculosis treatment outcomes for pregnant women.

The impact of preexposure prophylaxis among men who have sex with men: An individual-based model

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2017-06-01
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Journal of Acquired Immune Deficiency Syndromes
Objectives Preexposure prophylaxis (PrEP) is recommended for preventing HIV infection among individuals at high risk, including men who have sex with men (MSM). Although its individual-level efficacy is proven, questions remain regarding population-level impact of PrEP implementation. Design We...

Design and implementation of a community health worker HIV treatment and prevention intervention in an HIV hot spot fishing community in Rakai, Uganda

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2017-05-22
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Journal of the International Association of Providers of AIDS Care
Abstract Innovative approaches are needed to increase engagement in HIV treatment and prevention services, particularly in HIV hot spots. Here, we detail our design, training approach, and early implementation experiences of a community-based HIV intervention called "health scouts." The...

Treatment of pulmonary tuberculosis

Post Date: 
2017-04-27
Publication: 
Handbook of Tuberculosis
This chapter addresses the treatment of pulmonary tuberculosis highlighting drug classes, recommended regimens, adverse drug reactions, drug-drug interactions, and practical aspects of monitoring, The principles of treatment of latent tuberculosis are also addressed including whom to treat, what...

Clinical features and diagnosis of tuberculosis: primary infection and progressive pulmonary tuberculosis

Post Date: 
2017-04-27
Publication: 
Handbook of Tuberculosis
In this chapter, we will review the clinical manifestations of intrathoracic tuberculosis (TB), including pathophysiology and clinical features of primary and secondary or reactivation TB. Specific topics discussed are the physical examination, and microbiological, radiological, and immunological...

Extrapulmonary tuberculosis

Post Date: 
2017-04-27
Publication: 
Handbook of Tuberculosis
M. tuberculosis (MTB) can cause disease in almost any organ of the body. Extrapulmonary tuberculosis (EPTB) is defined as tuberculosis (TB) disease outside of the lung parenchyma [1]. Much like pulmonary TB, EPTB can occur as a primary infection or as reactivation of a latent focus with subsequent...

High burden of antimicrobial resistance and mortality among adults and children with community-onset bacterial infections in India

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2017-04-15
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Journal of Infectious Diseases
Of 133 isolates from 115 patients, 50% were multi-drug resistant; of 33 isolates tested for carbapenem susceptibility, 36% were resistant.

Resident doctors' attitudes toward tuberculosis patients

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2017-04-15
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Indian Journal of Tuberculosis
Background: The attitude of the resident doctors toward tuberculosis (TB) patients can affect their treatment seeking behavior, compliance to treatment as well as reinforce the stigma attached to the disease by the society at large. Aims: To assess the attitudes of resident medical doctors toward...

Novel interferon-gamma assays for diagnosing tuberculosis in young children in India

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2017-04-01
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International Journal of Tuberculosis and Lung Disease
Setting: The tuberculin skin test (TST) and interferon-gamma release assays (IGRAs) are used as supportive evidence to diagnose active tuberculosis (TB). Novel IGRAs could improve diagnosis, but data are lacking in young children. Design: Children (age 5 years or younger) with suspected TB were...

Prevalence of HIV testing provision at community organizations serving young people in a mid-Atlantic city, 2013-2014

Post Date: 
2017-03-31
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Public Health Reports
Objectives: Little is known about the prevalence of human immunodeficiency virus (HIV) testing at community organizations or the organizational characteristics associated with testing. The objective of this study was to describe (1) the prevalence of HIV testing at community organizations serving...

Reducing uncertainty for acute febrile illness in resource-limited settings: the current diagnostic landscape

Post Date: 
2017-03-27
Publication: 
The American Journal of Tropical Medicine and Hygiene
After decades of slow progress in diagnostics for acute febrile illness in resource-limited settings, a wave of converging advancements will enable clinicians in resource limited settings to reduce uncertainty for the diagnosis of acute febrile illness.

The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis

Post Date: 
2017-03-24
Publication: 
The Lancet Respiratory Medicine
Global tuberculosis incidence has declined marginally over the past decade, and tuberculosis remains out of control in several parts of the world including Africa and Asia. Although tuberculosis control has been effective in some regions of the world, these gains are threatened by the increasing...

High prevalence of cryptococcal antigenaemia amongst asymptomatic advanced HIV patients in Pune, India

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2017-03-21
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Indian Journal of Medical Microbiology
Methods : A prospective study was conducted in a large public sector ART centre and the inpatient wards of Sassoon Hospital, Pune, India. All consenting patients> 18 years of age with CD4 count <100 cells/mm3 were screened for CrAg by latex agglutination assay. Those with positive CrAg...

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Characteristics Associated with Mobile Phone Access among Tuberculosis Patents in Pune, India

Post Date: 
2016-12-04
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Ogale YP , Elf JL, Lokhande R, Mave V, Roy S, Gupta A, Golub J, Mathad J. Characteristics Associated with Mobile Phone Access among Tuberculosis Patents in Pune, India. 46th Union World Conference on Lung Health. International Union for Tuberculosis and Lung Disease. Cape Town, South Africa.

Presentation, Etiology, and Outcome of Febrile Indian Patients Differs by HIV Status

Post Date: 
2016-11-16
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Kadam D, Robinson M , Kagal A, Bharadwaj R, Raichur P, Kanade S, Sachs J, Gupte N, Gupta A, Mave V. Presentation, Etiology, and Outcome of Febrile Indian Patients Differs by HIV Status. 65th Annual Meeting, American Society of Tropical Medicine and Hygiene. Atlanta, GA.

Pharmacokinetic Aspects of 3HP in Special Populations

Post Date: 
2016-10-29
Mathad J. Pharmacokinetic Aspects of 3HP in Special Populations. 47th Union World Conference on Lung Health. International Union for Tuberculosis and Lung Disease. Liverpool, England.

IMPAACT P1078: Background, Design and Baseline Data

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2016-10-29
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Mathad J on behalf of Gupta A and P1078 Study Team. IMPAACT P1078: Background, Design and Baseline Data, 47th Union World Conference on Lung Health. International Union for Tuberculosis and Lung Disease. Liverpool, England.

The Impact of Health Seeking Behavior on Community-acquired Multi-drug Resistant Stool Colonization among Hospitalized Febrile Illness Patients in Pune, India

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2016-10-29
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Sachs J , Bharadwaj R, Khadse S, Kadam D, Kagal A, Shaikh N, Shingada K, Raichur P, Kanade S, Suryanvanshi N, Gupta A, Robinson M, Mave V. The Impact of Health Seeking Behavior on Community-acquired Multi-drug Resistant Stool Colonization among Hospitalized Febrile Illness Patients in Pune, India...

Choosing an ID Fellowship

Post Date: 
2016-10-29
Chida, N. Choosing an ID Fellowship. ID Week 2016. New Orleans, LA. 2016.

Etiology of Acute Febrile Illness among Hospitalized Adults and Children at a Public Tertiary-Care Center in Pune, India

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2016-10-27
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Robinson M , Balasubramanian U, Raichur P, Kadam D, Khadse S, Marbaniang I, Kanade S, Sachs J, Basavaraj A, Bharadwaj R, Kinikar A, Kulkarni V, Kagal A, Gupta A, Mave V. Etiology of Acute Febrile Illness among Hospitalized Adults and Children at a Public Tertiary-Care Center in Pune, India. ID Week...

Xpert® MTB/RIF Assay for Pulmonary Tuberculosis Diagnosis in Patients with Diabetes Mellitus

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2016-10-27
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Mave V , Gupte N, Meshram S, Kagal A, Gupta A, Bharadwaj R, Pradhan N, Deshmukh S, Atre S, Golub J. Xpert® MTB/RIF Assay for Pulmonary Tuberculosis Diagnosis in Patients with Diabetes Mellitus. 47th Union World Conference on Lung Health. International Union for Tuberculosis and Lung Disease...

TB Infection Prevalence, Incidence and Risk Factors among Child and Adult Household Contacts of Adult TB Cases in India

Post Date: 
2016-10-27
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Shivakumar SVBY , Chandrasekaran P, Thiruvengadam K, Gupte N, Mave V, Hannah LE, Kulkarni V, Gupte A, Deluca A, Gomathy NS, Sathyamurthi P, Paradkar M, Kohli R, Meshram S, Kagal A, Suryavanshi N, Ramachandran G, Thomas B, Dolla CK, Subramanyam B, Golub J, Swaminathan S, Gupta A. TB Infection...

Household Contact Tracing of Adult Pulmonary TB Patients in India: Prevalence of TB Disease and Infection

Post Date: 
2016-10-27
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Chandrasekaran P , Thiruvengadam K, Gupte N, Luck EH, Mave M, Gupte A, Gupta A, Swaminathan S. Household Contact Tracing of Adult Pulmonary TB Patients in India: Prevalence of TB Disease and Infection. ID Week 2016. New Orleans, LA. 2016.

Host Factors Associated with Poor Respiratory Health-Related Quality of Life in Pulmonary Tuberculosis

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2016-10-27
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Gupte A , Meshram S, Selvaraju S, Gupte N, Shivakumar SVBY, Paradkar M, Kohli R, Theruvengadam K, Suryavanshi N, Chandrasekaran P, Mave V, Swaminathan S, Salvi S, Checkley, W, Golub J, Gupta A. Host Factors Associated with Poor Respiratory Health-Related Quality of Life in Pulmonary Tuberculosis...

Impact of Drug Susceptibility Testing on Drug Choice in a Tuberculosis Cohort with High Rates of Drug Resistance from the Private Sector in Mumbai

Post Date: 
2016-10-27
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Udwadia ZF, Tornheim JA , Ganatra S, DeLuca A, Banka R, Gupta A. Impact of Drug Susceptibility Testing on Drug Choice in a Tuberculosis Cohort with High Rates of Drug Resistance from the Private Sector in Mumbai. ID Week 2016. New Orleans, LA. 2016.

A Case-control Study of Household Air Pollution and Tuberculosis in Women and Children in Pune, India

Post Date: 
2016-10-26
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Elf JL , Kinikar A, Khadse S, Mave V, Gupte N, Kulkarni V, Patekar S, Raichur P, Breysse PN, Gupta A, Golub JE. A Case-control Study of Household Air Pollution and Tuberculosis in Women and Children in Pune, India. 47th Union World Conference on Lung Health. International Union for Tuberculosis and...

TB and Diabetes in Pregnancy: Current Knowledge and Research Gaps

Post Date: 
2016-10-24
Gupta, A. TB and Diabetes in Pregnancy: Current Knowledge and Research Gaps. 47th Union World Conference on Lung Health. International Union for Tuberculosis and Lung Disease. Liverpool, England.

Sub-Therapeutic Concentrations of Anti-Tuberculosis Drugs in Children when Treated According to Indian Dosing Recommendation

Post Date: 
2016-10-24
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Guiastrennec B, Ramachandran G, Karlsson MO, Kumar H, Bhavani PK, Gangadevi NP, Swaminathan S, Gupta A, Dooley KE, Savic RM. Sub-Therapeutic Concentrations of Anti-Tuberculosis Drugs in Children when Treated According to Indian Dosing Recommendation. 9th Annual International Workshop on Clinical...

Vancomycin-resistant Enterococcal Bacteraemia: Is Daptomycin as Effective as Linezolid?

Post Date: 
2016-10-04
Mave, V. Vancomycin-resistant Enterococcal Bacteraemia: Is Daptomycin as Effective as Linezolid? Infectious Diseases Society of America. 2007 Annual Meeting. San Diego, CA. 2007.

Outreach Workers in the Prevention of Mother to Child Transmission of HIV (PMTCT) Programme in India: Challenges and Opportunities

Post Date: 
2016-07-21
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Suryavanshi N , Mave V, Kadam A, Kanade S, Sivalenka S, Sampath K, Harve P, Gupta RS, Hegde A, McKenzie-White J, Gupte N, Gupta A, Bollinger RC, Shankar AV. Outreach Workers in the Prevention of Mother to Child Transmission of HIV (PMTCT) Programme in India: Challenges and Opportunities. 21st...

A Cluster-Randomized Trial to Promote Combination HIV Prevention Using M-health-Supported CHWs in a High-Prevalence Fishing Community: Design and Baseline Characteristics of the mLAKE Trial in Rakai, Uganda

Post Date: 
2016-07-21
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Chang L, Mbabali I, Kong X, Hutton H, Long A, Thomas A, Bugos E, Ssekasanvu J, Kennedy C, Amico R, Nalugoda F, Reynolds S, Quinn T, Serwadda D, Wawer M, Gray R, Nakigozi G. A Cluster-Randomized Trial to Promote Combination HIV Prevention Using M-health-Supported CHWs in a High-Prevalence Fishing...

Rapid Diagnosis, Linkage and Treatment Initiation of Patients with Drug-resistant Tuberculosis in South Africa: The miLINC Solution to Improve Access to Care

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2016-07-20
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Farley JE , Seiguer S, Naicker M, McKenzie-White J, Greg C, Elmi M, Stevens W, Stewart-Isherwood L. Rapid Diagnosis, Linkage and Treatment Initiation of Patients with Drug-resistant Tuberculosis in South Africa: The miLINC Solution to Improve Access to Care. 21st International AIDS Conference...

High Risk for Loss to Follow-Up among Adolescents Living with HIV in Pune, India

Post Date: 
2016-07-19
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Nimkar S , Valvi C, Khadse S, Kadam D, Kinikar A, Marbaniang I, Rewari BB, Chandanwale A, Suryavanshi N, Patil S, Nevrekar N, Raichur P, Gupta A, Mave V. High Risk for Loss to Follow-Up among Adolescents Living with HIV in Pune, India. 21st International AIDS Conference. International AIDS Society...

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VIDEO: Amita Gupta, MD, MHS, reviews TB prevention in patients with HIV

Post Date: 
2016-02-24
Source: 
Infectious Disease News, via Healio
In this video with Healio.com, Amita Gupta, MD, MHS, associate professor medicine and international health and deputy director of the Center for Clinical Global Health Education at Johns Hopkins University School of Medicine, discusses research related to the prevention of tuberculosis in patients...

LEAP Program a Resource for Investigators of New Antiretrovirals

Post Date: 
2016-02-03
February 3, 2016—Baltimore, MD—The Johns Hopkins Center for Clinical Global Health Education, the Johns Hopkins Departments of Medicine and Pharmacology and Molecular Sciences, and the University of Liverpool launched a new website for an NIH-funded drug development resource called the Long-Acting/...

Up Close: Matthew Robinson

Post Date: 
2016-02-01
Looking for Causes of Fever in India “The most common reason Indians go to the doctor is for fever. The list of potential causes for fever in India and other low and middle income countries in tropical settings is extensive.” Matt Robinson, MD, is a Clinical Fellow whose research in India aims to...

Tuberculosis test may underreport in pregnant women with HIV

Post Date: 
2016-01-28
Source: 
Infectious Disease Advisor
Pregnancy may confound tuberculosis (TB) tests results in women with HIV, according to research published in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine .

Tuberculosis scare in HIV positive pregnant women: most widely-used tuberculosis test fails to diagnose illness

Post Date: 
2016-01-28
Source: 
International Business Times
The most commonly-used tuberculosis (TB) test, TST, has failed to detect TB in HIV positive pregnant women. A research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine has revealed that the TB test failed to accurately diagnose the...

Most commonly used TB test fails to accurately diagnose pregnant, HIV-positive women

Post Date: 
2016-01-25
Source: 
Infection Control Today
New research finds that the most commonly used test for tuberculosis fails to accurately diagnose TB in up to 50 percent of pregnant women who are HIV positive. The research published early online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine is...

BJGMC Clinical Research Site Observes World AIDS Day

Post Date: 
2015-12-14
Pune, India—To mark the struggle of those living with HIV and in commemoration of those who have lost their lives, the Clinical Research Site at Byramjee Jeejeebhoy Government Medical College (BJGMC CRS) participated in the National AIDS Trust’s World AIDS Day . Each year on December 1, events are...

CCGHE At The Union 2015

Post Date: 
2015-11-30
JOHNS HOPKINS CENTER FOR CLINICAL GLOBAL HEALTH EDUCATION AT THE UNION DECEMBER 2- 6 2015 | CAPE TOWN, SOUTH AFRICA Congratulations, Fogarty Fellows & Ujala Scholars! Dr. Anita Basavaraj, Ms. Jessica Elf, Dr. Sunita Girish, Dr. Nikhil Gupte, Dr. Aarti Kinikar, Dr. Rahul Lokhande, Dr. Jyoti...

Amid international growth, emocha gets grant to look at Maryland TB treatment

Post Date: 
2015-11-23
Source: 
Technical.ly Baltimore
emocha Mobile Health received a Small Business Innovation Research grant to further development of its mobile app that provides video-based healthcare observations in some cases where visits were previously required. The NIH grant, which is for about $200,000 over two years, will allow the Johns...

New cases of HIV in India could fall by 38% with early ART and better retention, finds study

Post Date: 
2015-10-23
Source: 
The BMJ
Starting antiretroviral therapy (ART) early in India could reduce new infections by 18% and AIDS mortality by 9%, a study has found. Better retention in care could reduce new cases by 38% over the next 20 years. The study used dynamic compartmental modelling to compare early ART initiation (at CD4...

CCGHE Faculty and Fogarty Scholars Meet with BJGMC Leadership

Post Date: 
2015-06-22
Baltimore, MD—Dr. Ajay S. Chandanwale, Dean, and other faculty leadership of Byramjee Jeejeebhoy Government Medical College (BJGMC) in Pune, India, arrived at the Johns Hopkins Medical Campus today to meet with CCGHE faculty and Fogarty Scholars who are in Baltimore attending the Hopkins Summer...

Mobile app developed by JHU grads helps monitor Ebola, tuberculosis patients

Post Date: 
2015-05-13
Source: 
The HUB at Johns Hopkins
Listening to Morad Elmi list off the recent developments at emocha Mobile Health Inc., the company he co-founded with fellow Johns Hopkins Carey Business School graduate Sebastian Seiguer, it's hard not to be impressed by the breadth and scope of the startup's work. In the past six months, the...

Ujala Foundation Recognized for Commitment to Hopkins Work in India

Post Date: 
2015-04-30
Back Row: Ashlyn Sowell, Kelly Dooley, Jessica Elf, Rupak Shivakoti, Natasha Chida, Akshay Gupte, Jyoti Mathad, Leslie Bernard. Front Row: Molly Bowen, Bob Bollinger, Kamla Gupta, Raj Gupta, Amita Gupta, Jane McKenzie-White Photography: Jon Cristofersen Baltimore, MD—On April 30, 2015, the Ujala...

Uniting mobile, education and pharma to combat HIV

Post Date: 
2015-04-07
Source: 
Healthcare Innovation
Health Innovation talks to Kris Sterkens, Company Group Chairman, Janssen Asia Pacific, about the TAMA project, as well as about some of the changes he has seen in the pharmaceutical industry because of IT and mobile.

Joint Pledge of More than $5 Million to Support Health Research and Education in India

Post Date: 
2014-11-18
Source: 
The Campaign for Johns Hopkins
Gifts from the Ujala and Wyncote Foundations will create professorships and named scholars at the Center for Clinical Global Health Education For more than two decades, the Center for Clinical Global Health Education (CCGHE) at Johns Hopkins Medicine has...

Baltimore tests mobile app for monitoring TB patients

Post Date: 
2014-10-24
Source: 
The Daily Record
The Baltimore City Health Department is piloting a mobile app that helps patients adhere to their medication regimen while reducing the burden on clinicians of monitoring those patients. The app, called miDOT, was developed by a company called emocha Mobile Health Inc., which is working out of the...

Health department launches TB trial with emocha app

Post Date: 
2014-10-22
Source: 
Technical.ly Baltimore
Tuberculosis is both tough to treat and medically cumbersome to manage. Under directly observed therapy, a medical professional has to watch a patient take his or her medication for at least six months. A Baltimore health IT startup may help lighten that load. The Baltimore City Health Department...

Where in the world: A look at JHU's global endeavors in India

Post Date: 
2014-09-01
Source: 
Johns Hopkins Gazette
Combating a TB epidemic India accounts for one-quarter of the cases of tuberculosis infection globally, and nearly 40 percent of its population is infected with the disease, which kills 1.4 million people a year. Researchers in the School of Medicine's Center for Clinical Global Health Education...

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