Research News

Venezuela flag
March 26, 2020

Foreign Policy: Dr. Kathleen Page argues that Venezuela's weak healthcare infrastructure leaves its people defenseless and presents a serious threat to global health, and she advocates for the global community to act now.

Clinical Research

Leadership
While we conduct research all over the world, the majority of our work is in India. Our Indo-JHU Clinical Research Partnership is located in Pune and is directed by Dr. Amita Gupta (Baltimore, MD), with onsite direction from Dr. Vidya Mave, Dr. Nishi Suryavanshi, and Dr. Nikhil Gupte (Pune). The Indo-JHU Partnership employs more than 200 people and in addition to our memberships in cosortia with many esteemed Indian research institutions, we have formal agreements with:

 
 

Predictive Value of TB-symptom Screen in HIV-infected and HIV-uninfected Pregnant Women in Pune, India

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2014-10-28
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This study was terminated July 17, 2017. This is a cross sectional observational study will be conducted at BJGMC to establish what the predictive value of the WHO TB symptom screen is in pregnant women in India. We hypothesize that the WHO TB symptom screen will have a higher positive predictive...

miLINC: MDR-TB South Africa - Patient Linkage to and Retention in Care

Post Date: 
2014-10-06
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Mycobacterium tuberculosis (TB) remains the leading cause of death among persons living with human immunodeficiency virus and acquired immunodeficiency syndrome (HIV/AIDS) in southern Africa. Drug-resistant TB remains a growing threat to public health despite advances made in diagnosis and...

Project S.O.A.R. (Supporting Operational AIDS Research): Positive Health Dignity and Prevention Sub-Project

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2014-09-15
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Dr. Larry Chang is a Co-Investigator for this effort. Purpose The goal of Project SOAR (Supporting Operational AIDS Research) is to improve the quality and impact of HIV and AIDS program outcomes by strengthening operations research and evaluation activities. Project SOAR supports the PEPFAR...

Impact of Immune Changes of HIV and Stages of Pregnancy on Tuberculosis

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2014-09-01
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This is the Parent Study for CCGHE’s PRACHITI (PRegnancy And CHanges In TuberculosIs) effort. It's supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development at the U.S. National Institutes of Health. Purpose: TB is a leading cause of maternal mortality,...

Diagnosis of Tuberculosis Infection and Th1 Immune Response in Pregnant Women in India

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2014-09-01
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This study was terminated April 16, 2018. Tuberculosis (TB) disease is a major cause of mortality among Indian women of reproductive age; approximately 20-50% of women in India are latently infected with Mycobacterium tuberculosis (MTB). Due to immune changes of pregnancy, women are particularly at...

TBM Kids Substudy: Assessment of Neurocognitive Functions in Children with Tuberculosis Meningitis and Healthy Control Children Using the Mullen Scale of Early Learning Attending a Tertiary Care Public Hospital in Pune, India

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2014-09-01
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Objectives: The aim of the present study is to examine the neurological deficit in TBM kids and for that we need to assess, feasibility of the MSEL in our set up an Indian population of healthy children and children with meningitis in particular TB meningitis(TBM). The primary objective of the...

Evaluating Demand Generation (Stylish Man) for HIV/Family Planning Services, Rakai, Uganda

Post Date: 
2014-08-01
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Dr. Larry Chang is co-investigator of this effort to test a novel approach to promoting HIV services in Rakai, Uganda. The Stylish Man Program, attempts to “demedicalize” HIV prevention and care in a public health campaign designed to normalize HIV care as part of self care for African men. The...

A5279: Phase III Clinical Trial of Ultra-Short-Course Rifapentine/Isoniazid for the Prevention of Active Tuberculosis in HIV-infected Individuals with Latent Tuberculosis Infection

Post Date: 
2014-06-30
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This study ended April 27, 2015; it was conducted under the AIDS Clinical Trials Group (ACTG) and funded by the U.S. National Institutes of Health. Dr. Amita Gupta was Protocol Co-Vice Chair for this multinational clinical trial being conducted in Botswana, Brazil, Haiti, Kenya, Malawi, Peru,...

ART Study 1: Database: Epidemiology of HIV/AIDS and Associated Comorbidities in a Public Antiretroviral Treatment (ART) Clinic at BJGMC in Pune

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2014-06-14
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Since 2004, the National AIDS Control Program of India has been rolling out free antiretroviral therapy. Byramjee Jeejeebhoy Government Medical College (BJGMC), located in Pune, India, is now the largest HIV clinic in India, with over 26,000 adult and pediatric patients registered since 2005. We...

Optimizing Treatment to Improve TBM Outcomes in Children

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2014-05-01
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This study, known as TBM Kids, is being conducted in India and Malawi. Primary Objectives To characterize the pharmacokinetics (PK) (plasma and cerebrospinal fluid (CSF)) of rifampicin given at model-derived optimal daily doses and levofloxacin in children ages 6 months to 12 years of age with TBM...

P1078: A Phase IV Randomized Double-Blind Placebo-Controlled Trial to Evaluate the Safety of Immediate (Antepartum-Initiated) Versus Deferred (Postpartum-Initiated) Isoniazid Preventive Therapy Among HIV-Infected Women in High TB Incidence Settings

Post Date: 
2014-04-01
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This is a clinical trial conducted under the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Network and funded by the U.S. National Institutes of Health. Dr. Amita Gupta is Protocol Chair for this multinational clinical trial being conducted in Botswana, Haiti, South...

Pulmonary and Functional Status of Patients with Pulmonary Mycobacterium Tuberculosis Post-treatment in Lima, Peru

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2014-01-01
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To conduct a longitudinal study evaluating the hypothesis that pulmonary function and functional status (functional capacity and quality of life) is reduced among individuals previously treated for pulmonary tuberculosis compared to those without a history of tuberculosis.

Evaluation of HIV Disease Burden in Hospitalized Patients at Sassoon General Hospital in Pune, India

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2013-11-18
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This study was terminated September 13, 2005. The goal of this project was to conduct both a retrospective and prospective epidemiological study of the burden of HIV disease at Sassoon General Hospital. The specific objectives of the study were to establish the proportion of HIV-infected...

Tuberculosis Noon Conference

Post Date: 
2013-10-24
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This effort ended in 2015. As part of the BJGMC-Johns Hopkins India Fogarty Training Program, from 2013-2015 CCGHE hosted the live Tuberculosis Noon Conference webcast. Led by Drs. Maunank Shah, Jonathan Golub, and Richard Chaisson, these webcast meetings brought together Johns Hopkins TB...

Cohort for Tuberculosis Research by the Indo-US Medical Partnership (C-TRIUMPH)

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2013-09-28
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Collaboratively funded by the US NIH, India’s Department of Biotechnology [DBT], and Indian Council of Medical Research, the Cohort for TB Research by the Indo-US Medical Partnership (C-TRIUMPH) is an Indo-US research consortium that is part of RePORT India, a countrywide consortium for TB research...

Assessing the Association of Indoor Air Pollution with Tuberculosis in Adult Women and Children under 5 Years of Age

Post Date: 
2013-09-15
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This study is conducted the Cohort for Tuberculosis Research by the Indo-US Medical Partnership (C-TRIUMPH) under the Regional Prospective Observational Research for Tuberculosis (RePORT) Network, an international TB consortium. Addressing social and environmental risk factors contributing to TB...

Community Home Based India Prevention of Mother to Child Transmission of HIV (COMBIND)

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2013-09-02
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This study ended May 14, 2019. CCGHE is assessing whether equipping Community Health Workers with mobile health technology and involving them in technology training and personal empowerment seminars can help prevent mother-to-child...

Impact of Diabetes on TB Treatment Outcomes

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2013-02-01
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CCGHE, the JHU Center for TB Research and BJGMC have been awarded a $2.5 million dollar NIH grant (2013-2018) to conduct a study to evaluate treatment outcomes among Indian patients with both diabetes mellitus and active TB. This study is assessing the prevalence of impaired glucose or frank...

Bacterial Antimicrobial Resistance Patterns in Pune, India

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2013-01-10
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This study was terminated September 24, 2019. Evaluate etiology of acute fever and bacterial drug resistance patterns among adults and children in India.

Feasibility and Acceptability of Smartphone-Based Ecological Momentary Assessment of Alcohol Use Among African American Men Who Have Sex With Men in Baltimore

Post Date: 
2013-01-01
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This study provides evidence to support the feasibility and acceptability of using Ecological Momentary Assessment (EMA ) methods for collecting data on alcohol use among African American men who have sex with men living in urban settings. These data provide the basis for future studies of EMA-...

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Addressing knowledge gaps and prevention for tuberculosis-infected Indian adults: a vital part of elimination

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2018-05-02
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BMC Infectious Diseases
BMC Infectious Diseases : Our survey among TB patients' household contacts with evidence of recent exposure found that knowledge is poor and families are confused about disease transmission.

Hepatotoxicity during isoniazid preventive therapy and antiretroviral therapy in people living with HIV with severe immunosuppression: a secondary analysis of a multi-country open-label randomized controlled clinical trial

Post Date: 
2018-05-01
Publication: 
Journal of Acquired Immune Deficiency Syndromes
BACKGROUND: Hepatotoxicity associated with isoniazid preventive therapy (IPT) and antiretroviral therapy (ART) has not been well studied in severely immunosuppressed people with HIV. Our objective was to determine risk factors for hepatotoxicity in severely immunosuppressed individuals...

MDR-TB in children: back to the basics

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2018-05-01
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The International Journal of Tuberculosis and Lung Disease
IJTLD: Summary of the Pediatric Multidrug-Resistant Tuberculosis Clinical Trials Landscape Meeting: a primer of current directions.

Advancing patient-centered care in tuberculosis management: A mixed-methods appraisal of video directly observed therapy

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2018-04-26
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Open Forum Infectious Diseases
BACKGROUND: Directly observed therapy (DOT) remains an integral component of treatment support and adherence monitoring in tuberculosis care. In-person DOT is resource intensive and often burdensome for patients. Video DOT (vDOT) has been proposed as an alternative to increase treatment...

Shorter treatment for minimal tuberculosis (TB) in children (SHINE): a study protocol for a randomised controlled trial

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2018-04-19
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Trials
Trials: Evidence for TB treatment in kids is largely based on adult studies. The SHINE study aims to fix this

Migration and risk of HIV acquisition in Rakai, Uganda: a population-based cohort study

Post Date: 
2018-04-15
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Lancet HIV
BACKGROUND: In sub-Saharan Africa, migrants typically have higher HIV prevalence than non-migrants; however, whether HIV acquisition typically precedes or follows migration is unknown. We aimed to investigate the risk of HIV after migration in Rakai District, Uganda. ...

Prevention of HIV-1 transmission through breastfeeding:efficacy of safety of maternal antiretroviral therapy versus infant nevirapine prophylaxis for duration of breastfeeding in HIV-1-infected women with high CD4 cell count (IMPAACT PROMISE)

Post Date: 
2018-04-01
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Journal of Acquired Immune Deficiency Syndromes
BACKGROUND: No randomized trial has directly compared the efficacy of prolonged infant antiretroviral prophylaxis versus maternal antiretroviral therapy (mART) for prevention of mother-to-child transmission throughout the breastfeeding period. SETTING: Fourteen...

HIV viral suppression and geospatial patterns of HIV antiretroviral therapy treatment facility use in Rakai, Uganda

Post Date: 
2018-03-27
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AIDS
OBJECTIVE: To assess geospatial patterns of HIV antiretroviral therapy (ART) treatment facility use and whether they were impacted by viral load suppression. METHODS: We extracted data on the location and type of care services utilized by HIV-positive persons...

Pyrosequencing to resolve discrepant Xpert MTB/RIF and Mycobacterial Growth Indicator Tube 960

Post Date: 
2018-03-26
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Lung India
Lung India: Indo-JHU researchers find that pyrosequencing can clear up discrepancies about drug resistance in TB.

Screening and diagnosis of gestational diabetes in India: A systematic review and meta analysis

Post Date: 
2018-03-26
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Acta Diabetologica
Review article on prevalence and screening and diagnostic methods for gestational diabetes in India.

Intestinal barrier dysfunction and microbial translocation in HIV-infected pregnant women is associated with preterm birth

Post Date: 
2018-03-24
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Clinical Infectious Diseases
Our results show select immune markers can identify women at higher risk for PTB in HIV-1-infected populations and suggest modulating gut barrier integrity and microbial translocation may affect PTB.

Mobile phone incentives for childhood immunizations in rural India

Post Date: 
2018-03-19
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Pediatrics
In Pediatrics: Incentives and technology can improve immunization coverage in young children in resource-poor settings.

How feasible is pharmaceutical regulation in India?

Post Date: 
2018-01-29
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The Lancet Global Health
Lancet Global Health: Dr. Sachin Atre outlines factors that complicate pharmaceutical regulation in India, which is a component of WHO's Global Antimicrobial Resistance Action Plan.

The validity of self-reported antiretroviral use in persons living with HIV: a population-based study

Post Date: 
2018-01-28
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Publication: 
AIDS
OBJECTIVE: To assess the validity of self-reported antiretroviral therapy use (ART) using population-based cohort data. METHODS: Self-reported ART use and nonuse was compared with a validated laboratory assay in 557 HIV-positive participants in the Rakai...

¡Vive!: Designing an intervention to improve timely HIV diagnosis among Latino immigrant men

Post Date: 
2018-01-23
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Progress in Community Health Partnerships
Background: Latinos, particularly immigrant men, are more likely to present late to care for human immunodeficiency virus (HIV) infection. Objectives: This manuscript describes the development of ¡Sólo Se Vive Una Vez! (¡Vive!) (You Only Live Once), a multilevel (...

Gender-based violence screening methods preferred by women visiting a public hospital in Pune, India

Post Date: 
2018-01-22
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BMC Womens Health
BMC Womens Health : In our study, 23% of women reported experiencing gender based violence, and 90% reported they had never been asked about it in the healthcare setting.

Secondhand smoke exposure and validity of self-report in low-income women and children in India

Post Date: 
2018-01-10
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Pediatrics
Pediatrics: Dr. Jessica Elf and colleagues evaluated the validity of standard self-reported measures for secondhand smoke (SHS) exposure among women and children in urban India.

What will it take to reduce HIV incidence in the United States: A mathematical modeling analysis

Post Date: 
2018-01-06
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Open Forum Infectious Diseases
Modeling and simulations suggest that cutting HIV incidence in half by 2025 will require 95% of people living with HIV to be engaged in care.

How reliable and valid are the self-reports on sexual behavior among HIV discordant couples from Pune, India?

Post Date: 
2018-01-01
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Psychology, Health, and Medicine
Reliability of self-reported sexual and safe sex behavior among heterosexual HIV discordant couples was assessed by matching individual responses of couples to a common set of questions and validated by matching with pregnancy and seroconversion during study period. Demographic, clinical and...

Suboptimal antituberculosis drug concentrations and outcomes in small and HIV‐coinfected children in India: Recommendations for dose modifications

Post Date: 
2017-12-16
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Clinical Pharmacology and Therapeutics
This work aimed to evaluate the once-daily antituberculosis treatment as recommended by the new Indian pediatric guidelines. Isoniazid, rifampin, and pyrazinamide concentration-time profiles and treatment outcome were obtained from 161 Indian children with drug-sensitive tuberculosis...

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Alcohol Use Among Adult Pulmonary and Extra-pulmonary TB Cases in the C-TRIUMPH India Cohort

Post Date: 
2017-02-03
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John S , DeLuca A, Paradkar M, Nayagam R, Shivakumar SVBY, Gupte A, Gupte N, Thomas B, Suryavanshi N, Kolhi R, Golub J, Kulkarni V, Pradhan N, Mave V, Chandrasekaran P, Gupta A. Alcohol Use Among Adult Pulmonary and Extra-pulmonary TB Cases in the C-TRIUMPH India Cohort. 6th Annual Regional...

Impact of Immune Changes of Pregnancy and HIV Infection on Tuberculosis

Post Date: 
2017-02-03
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Mathad J, Alexander M , Bhosale R, Naik S, Shivakoti R, Mave V, Suryavanshi N, Gupte N, Kulkarni V, Pradan N, Patil N, Gupta A. Impact of Immune Changes of Pregnancy and HIV Infection on Tuberculosis. 6th Annual Regional Prospective Observational Research for Tuberculosis (RePORT) India Joint...

Host Factors Associated with Poor Respiratory Health-Related Quality of Life in Pulmonary Tuberculosis

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2017-02-03
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Gupte A , Meshram S, Selvaraju S, Gupte N, Shivakumar SVBY, Paradkar M, Kohli R, Theruvengadam K, Suryavanshi N, Chandrasekaran P, Mave V, Swaminathan S, Salvi S, Checkley, W, Golub J, Gupta A. Host Factors Associated with Poor Respiratory Health-Related Quality of Life in Pulmonary Tuberculosis...

Descriptive Baseline Characteristics, Treatment Outcomes and Biorepository of Pediatric TB Cases in CTRIUMPh-RePORT India Prospective Cohort

Post Date: 
2017-02-03
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Paradkar M , Kavitha D, Shiva Kumar SVBY, Khadse S, Khwaja S, Hari K, Rani N, Thiruvengadam K, Gupte N, Raskar S, Jain D, Suryavanshi S, Kohli R, Kulkarni V, Pradhan N, Sathyamurthi B, Tornheim J, Gupte A, DeLuca A, Mave V, Chandrasekaran P, Gupta A for the CTRIUMPH Study Team. Descriptive Baseline...

Household Contact Tracing of Adult Pulmonary TB Patients in India: Prevalence of TB Disease and Infection

Post Date: 
2017-02-03
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Chandrasekaran P , Thiruvengadam K, Gupte N, Luck EH, Mave M, Gupte A, Gupta A, Swaminathan S. Household Contact Tracing of Adult Pulmonary TB Patients in India: Prevalence of TB Disease and Infection. 6th Annual Regional Prospective Observational Research for Tuberculosis (RePORT) India Joint...

Attrition among HIV-infected Adolescent Girls and Young Women in Pune, India

Post Date: 
2016-12-06
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Nimkar S , Kadam D, Marbaniang I, Suman R, Gupte N, Salvi S, Suryavanshi N, Gupta A, Mave V. Attrition among HIV-infected Adolescent Girls and Young Women in Pune, India. Center for AIDS Research. Women and HIV: Inter-CFAR Joint Symposium on HIV Research in Women. Birmingham, AL.

Characteristics of HIV-infected Transgender Women Registered under Programmatic Conditions in Pune, India

Post Date: 
2016-12-06
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Marbaniang I , Kadam D, Gupte N, Suman R, Salvi S, Nimkar S, Suryavanshi N, Gupta A, Mave V. Characteristics of HIV-infected Transgender Women Registered under Programmatic Conditions in Pune, India. Center for AIDS Research. Women and HIV: Inter-CFAR Joint Symposium on HIV Research in Women...

Spousal Serostatus Affects Retention in Care among Married HIV Infected Women in Pune, India

Post Date: 
2016-12-06
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Nimkar S , Kadam D, Marbaniang I< Suman R, Gupte N, Salvi S, Suryavanshi N, Gupta A, Mave V. Spousal Serostatus Affects Retention in Care among Married HIV Infected Women in Pune, India. Center for AIDS Research. Women and HIV: Inter-CFAR Joint Symposium on HIV Research in Women. Birmingham, AL.

Characteristics Associated with Mobile Phone Access among Tuberculosis Patents in Pune, India

Post Date: 
2016-12-04
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Ogale YP , Elf JL, Lokhande R, Mave V, Roy S, Gupta A, Golub J, Mathad J. Characteristics Associated with Mobile Phone Access among Tuberculosis Patents in Pune, India. 46th Union World Conference on Lung Health. International Union for Tuberculosis and Lung Disease. Cape Town, South Africa.

Presentation, Etiology, and Outcome of Febrile Indian Patients Differs by HIV Status

Post Date: 
2016-11-16
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Kadam D, Robinson M , Kagal A, Bharadwaj R, Raichur P, Kanade S, Sachs J, Gupte N, Gupta A, Mave V. Presentation, Etiology, and Outcome of Febrile Indian Patients Differs by HIV Status. 65th Annual Meeting, American Society of Tropical Medicine and Hygiene. Atlanta, GA.

IMPAACT P1078: Background, Design and Baseline Data

Post Date: 
2016-10-29
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Mathad J on behalf of Gupta A and P1078 Study Team. IMPAACT P1078: Background, Design and Baseline Data, 47th Union World Conference on Lung Health. International Union for Tuberculosis and Lung Disease. Liverpool, England.

The Impact of Health Seeking Behavior on Community-acquired Multi-drug Resistant Stool Colonization among Hospitalized Febrile Illness Patients in Pune, India

Post Date: 
2016-10-29
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Sachs J , Bharadwaj R, Khadse S, Kadam D, Kagal A, Shaikh N, Shingada K, Raichur P, Kanade S, Suryanvanshi N, Gupta A, Robinson M, Mave V. The Impact of Health Seeking Behavior on Community-acquired Multi-drug Resistant Stool Colonization among Hospitalized Febrile Illness Patients in Pune, India...

Choosing an ID Fellowship

Post Date: 
2016-10-29
Chida, N. Choosing an ID Fellowship. ID Week 2016. New Orleans, LA. 2016.

Pharmacokinetic Aspects of 3HP in Special Populations

Post Date: 
2016-10-29
Mathad J. Pharmacokinetic Aspects of 3HP in Special Populations. 47th Union World Conference on Lung Health. International Union for Tuberculosis and Lung Disease. Liverpool, England.

Xpert® MTB/RIF Assay for Pulmonary Tuberculosis Diagnosis in Patients with Diabetes Mellitus

Post Date: 
2016-10-27
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Mave V , Gupte N, Meshram S, Kagal A, Gupta A, Bharadwaj R, Pradhan N, Deshmukh S, Atre S, Golub J. Xpert® MTB/RIF Assay for Pulmonary Tuberculosis Diagnosis in Patients with Diabetes Mellitus. 47th Union World Conference on Lung Health. International Union for Tuberculosis and Lung Disease...

TB Infection Prevalence, Incidence and Risk Factors among Child and Adult Household Contacts of Adult TB Cases in India

Post Date: 
2016-10-27
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Shivakumar SVBY , Chandrasekaran P, Thiruvengadam K, Gupte N, Mave V, Hannah LE, Kulkarni V, Gupte A, Deluca A, Gomathy NS, Sathyamurthi P, Paradkar M, Kohli R, Meshram S, Kagal A, Suryavanshi N, Ramachandran G, Thomas B, Dolla CK, Subramanyam B, Golub J, Swaminathan S, Gupta A. TB Infection...

Household Contact Tracing of Adult Pulmonary TB Patients in India: Prevalence of TB Disease and Infection

Post Date: 
2016-10-27
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Chandrasekaran P , Thiruvengadam K, Gupte N, Luck EH, Mave M, Gupte A, Gupta A, Swaminathan S. Household Contact Tracing of Adult Pulmonary TB Patients in India: Prevalence of TB Disease and Infection. ID Week 2016. New Orleans, LA. 2016.

Host Factors Associated with Poor Respiratory Health-Related Quality of Life in Pulmonary Tuberculosis

Post Date: 
2016-10-27
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Gupte A , Meshram S, Selvaraju S, Gupte N, Shivakumar SVBY, Paradkar M, Kohli R, Theruvengadam K, Suryavanshi N, Chandrasekaran P, Mave V, Swaminathan S, Salvi S, Checkley, W, Golub J, Gupta A. Host Factors Associated with Poor Respiratory Health-Related Quality of Life in Pulmonary Tuberculosis...

Impact of Drug Susceptibility Testing on Drug Choice in a Tuberculosis Cohort with High Rates of Drug Resistance from the Private Sector in Mumbai

Post Date: 
2016-10-27
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Udwadia ZF, Tornheim JA , Ganatra S, DeLuca A, Banka R, Gupta A. Impact of Drug Susceptibility Testing on Drug Choice in a Tuberculosis Cohort with High Rates of Drug Resistance from the Private Sector in Mumbai. ID Week 2016. New Orleans, LA. 2016.

Etiology of Acute Febrile Illness among Hospitalized Adults and Children at a Public Tertiary-Care Center in Pune, India

Post Date: 
2016-10-27
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Robinson M , Balasubramanian U, Raichur P, Kadam D, Khadse S, Marbaniang I, Kanade S, Sachs J, Basavaraj A, Bharadwaj R, Kinikar A, Kulkarni V, Kagal A, Gupta A, Mave V. Etiology of Acute Febrile Illness among Hospitalized Adults and Children at a Public Tertiary-Care Center in Pune, India. ID Week...

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Feasibility Study Complete on Preventive Therapy for Household Contacts of MDR-TB Patients in Pune, India

Post Date: 
2016-03-31
March 31, 2016—Pune, India—The Baltimore-Washington-India Clinical Trials Unit is pleased to announce that the BJGMC Clinical Research Site (BJGMC-CRS) in Pune, India, just finished the feasibility study titled A5300/IMPAACT2003: Study of MDR-TB Cases and their Household Contacts: Operational...

In Many Regions, World Tuberculosis Day is Every Day

Post Date: 
2016-03-24
India Assumes the Greatest Burden Each year on March 24, the world pauses to reflect on the devastation that tuberculosis causes globally. TB is preventable and treatable, and it disproportionately and gravely affects resource-limited regions of the world. The World Health Organization reports that...

Proactively treating HIV patients at risk for tuberculosis with multi-drug TB regimens doesn't save more lives

Post Date: 
2016-03-20
Source: 
Health Canal
The number one killer of HIV patients in resource-limited areas, including parts of Africa and India, is tuberculosis (TB), underscoring the need for optimal treatments and effective strategies to address this deadly co-infection. But TB is harder to detect in HIV-infected patients and diagnostic...

Proactively treating HIV patients at risk for tuberculosis with multi-drug TB regimens doesn't save more lives

Post Date: 
2016-03-18
Source: 
Infection Control Today
In what investigators say is a surprise finding, results of a new study appear to strongly affirm the effectiveness of prescribing the anti-tuberculosis drug isoniazid alone — in place of the standard four-drug regimen — to prevent TB and reduce death in

Common TB treatment in HIV: no added benefit?

Post Date: 
2016-03-18
Source: 
Pharmaceutical Processing Online
In a report on the REMEMBER (Reducing Early Mortality and Early Morbidity by Empiric Tuberculosis Treatment) study—a 10-nation, randomized clinical trial of adult outpatients—investigators concluded that there was no added benefit of using four drugs for TB over just using one drug, isoniazid...

4-drug tuberculosis treatment among HIV/AIDS patients does not save more lives

Post Date: 
2016-03-18
Source: 
MedIndia
There was no added benefit of using four drugs for tuberculosis over using just one drug, isoniazid, to save lives in people with advanced HIV/AIDS, revealed a report on the so-called REMEMBER (Reducing Early Mortality and Early Morbidity by Empiric Tuberculosis Treatment) study—a 10 nation,...

Multidrug TB prophylaxis not needed in advanced HIV

Post Date: 
2016-03-18
Source: 
MedPage Today
Patients with advanced HIV infection initiating anti-retroviral therapy who were treated with isoniazid alone to prevent tuberculosis had similar survival rates as patients treated with a standard four-drug anti-tuberculosis regimen in a multi-national, randomized, controlled trial.

Common treatment of TB in advanced HIV patients doesn't save more lives

Post Date: 
2016-03-17
Source: 
Medical Xpress
In a report on the so-called REMEMBER (Reducing Early Mortality and Early Morbidity by Empiric Tuberculosis Treatment) study—a 10-nation, randomized clinical trial of adult outpatients—investigators concluded that there was no added benefit of using four drugs for TB over just using one drug,...

Proactively treating HIV patients at risk for tuberculosis with multidrug TB therapy doesn’t save more lives

Post Date: 
2016-03-17
In what investigators say is a surprise finding, results of a new study appear to strongly affirm the effectiveness of prescribing the anti-tuberculosis drug isoniazid alone — in place of the standard four-drug regimen — to prevent TB and reduce death in people with advanced HIV/AIDS infections...

CCGHE at CROI 2016

Post Date: 
2016-02-29
JOHNS HOPKINS CENTER FOR CLINICAL GLOBAL HEALTH EDUCATION AT CROI 2016 FEBRUARY 22-25 2016 | BOSTON, MASSACHUSETTS TUESDAY, FEBRUARY 23 Combination HIV Prevention and HIV Incidence in a Ugandan Hotspot Fishing Community. Poster Presentation. Session: HIV Testing and Prevention. Authors: Kagaayi J,...

Now, docs to get TB leave as cases mount

Post Date: 
2016-02-24
Source: 
Pune Mirror
Too many cases of tuberculosis (TB) among medical trainees and resident doctors in the state have prompted the medical education department to sanction medical leaves exclusively for the malady. This is the first time any state has taken such a step in India. Unusual working hours; close contact...

VIDEO: Amita Gupta, MD, MHS, reviews TB prevention in patients with HIV

Post Date: 
2016-02-24
Source: 
Infectious Disease News, via Healio
In this video with Healio.com, Amita Gupta, MD, MHS, associate professor medicine and international health and deputy director of the Center for Clinical Global Health Education at Johns Hopkins University School of Medicine, discusses research related to the prevention of tuberculosis in patients...

LEAP Program a Resource for Investigators of New Antiretrovirals

Post Date: 
2016-02-03
February 3, 2016—Baltimore, MD—The Johns Hopkins Center for Clinical Global Health Education, the Johns Hopkins Departments of Medicine and Pharmacology and Molecular Sciences, and the University of Liverpool launched a new website for an NIH-funded drug development resource called the Long-Acting/...

Up Close: Matthew Robinson

Post Date: 
2016-02-01
Looking for Causes of Fever in India “The most common reason Indians go to the doctor is for fever. The list of potential causes for fever in India and other low and middle income countries in tropical settings is extensive.” Matt Robinson, MD, is a Clinical Fellow whose research in India aims to...

Tuberculosis test may underreport in pregnant women with HIV

Post Date: 
2016-01-28
Source: 
Infectious Disease Advisor
Pregnancy may confound tuberculosis (TB) tests results in women with HIV, according to research published in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine .

Tuberculosis scare in HIV positive pregnant women: most widely-used tuberculosis test fails to diagnose illness

Post Date: 
2016-01-28
Source: 
International Business Times
The most commonly-used tuberculosis (TB) test, TST, has failed to detect TB in HIV positive pregnant women. A research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine has revealed that the TB test failed to accurately diagnose the...

Most commonly used TB test fails to accurately diagnose pregnant, HIV-positive women

Post Date: 
2016-01-25
Source: 
Infection Control Today
New research finds that the most commonly used test for tuberculosis fails to accurately diagnose TB in up to 50 percent of pregnant women who are HIV positive. The research published early online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine is...

BJGMC Clinical Research Site Observes World AIDS Day

Post Date: 
2015-12-14
Pune, India—To mark the struggle of those living with HIV and in commemoration of those who have lost their lives, the Clinical Research Site at Byramjee Jeejeebhoy Government Medical College (BJGMC CRS) participated in the National AIDS Trust’s World AIDS Day . Each year on December 1, events are...

CCGHE At The Union 2015

Post Date: 
2015-11-30
JOHNS HOPKINS CENTER FOR CLINICAL GLOBAL HEALTH EDUCATION AT THE UNION DECEMBER 2- 6 2015 | CAPE TOWN, SOUTH AFRICA Congratulations, Fogarty Fellows & Ujala Scholars! Dr. Anita Basavaraj, Ms. Jessica Elf, Dr. Sunita Girish, Dr. Nikhil Gupte, Dr. Aarti Kinikar, Dr. Rahul Lokhande, Dr. Jyoti...

Amid international growth, emocha gets grant to look at Maryland TB treatment

Post Date: 
2015-11-23
Source: 
Technical.ly Baltimore
emocha Mobile Health received a Small Business Innovation Research grant to further development of its mobile app that provides video-based healthcare observations in some cases where visits were previously required. The NIH grant, which is for about $200,000 over two years, will allow the Johns...

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