Technology

Clinical Sites:

Study is assessing whether computer-delivered alcohol screening and intervention helps overcome barriers to treatment in India.

Evaluation of Video-Based Directly Observed Therapy for Tuberculosis in India

Post Date:

2018-05-14

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This study was designed to evaluate Directly Observed Therapy conducted through miDOT, a secure mobile health interface, with traditional in-person Directly Observed Therapy.

Multidisciplinary Research Training to Understand and Reduce HIV Incidence in Uganda

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2018-05-10

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Dr. Larry Chang is PI for this multi-year (2018-2023) training grant sponsored by the Fogarty International Center at the National Institute of Health. Abstract While substantial progress has been made in the global HIV response, impact has been uneven. Uganda provides a prime case study. Uganda...

Characteristics Associated with Mobile Phone Usage among TB Populations in Pune, India

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2017-10-02

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With 8.6 million people affected worldwide in 2012, the control and prevention of tuberculosis (TB) has become an international priority. In order to reduce burdens and achieve global goals for TB control, new and innovative tools are necessary. With a growing number of mobile phone subscriptions...

HIV Antiretroviral Selection Support and Interactive Search Tool (ASSIST)

Post Date:

2017-09-01

HIV-ASSIST is an evidence based, web platform designed and developed by experts at Johns Hopkins University to assist and educate clinicians in personalizing ARV regimens for their patients. This tool is designed to be used for adult patients only. The goals are to provide: Patient-centric...

LaMocha: A Mobile Technology to Promote HIV Testing among Immigrant Latino Men

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2016-12-15

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Foreign-born Latino males have a high risk of late HIV diagnosis and presentation to care, which can lead to poor clinical outcomes and ongoing HIV transmission in the community. We propose to evaluate if tailored videos delivered through a tablet by a Latino Health Worker and regular SMS text...

mHealth-enhanced Peer Navigation Intervention for PrEP Delivery among MSM at STD Clinics

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2016-08-01

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Using mixed methodology (quantitative surveys, qualitative interviews, and administrative data), this study will assess acceptability and feasibility of an mHealth-enhanced peer navigation to promote PrEP initiation, retention and adherence among men who have sex with men (MSM) in the Baltimore...

miDOT (Directly Observed Therapy)

Post Date:

2015-11-01

Designed by Dr. Maunank Shah, the miDOT mobile health application is a video-based Directly Observed Therapy interface that uses the emocha Mobile Health platform to remotely connect patients on long-term tuberculosis therapy with clinicians who are required to witness patients taking...

Smallpox Comes Back to Life in Microbe Hunters

Post Date:

2015-10-22

Baltimore, MD—The world may have been declared free of smallpox in 1980, but the eradication campaign was revived Tuesday in a multimedia presentation at the Johns Hopkins Medical Campus. The event featured a screening of the film Microbe Hunters: Smallpox , by the Johns Hopkins Center for Clinical...

Community Health Workers, mHealth, and Combination HIV Prevention in a Hotspot: A Randomized Trial (mLAKE)

Post Date:

2015-04-01

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Led by Dr. Larry Chang, the mLAKE study in Uganda is examining whether community health workers equipped with cellphones and the emocha Mobile Health platform are able to successfully promote HIV treatment and prevention services in households in a fishing community in East Africa with a very high...

Salud al Dia

Post Date:

2014-11-01

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This initiative is intended to address healthcare disparities among Latino children in Baltimore by increasing engagement of limited English proficiency (LEP) Latino parents in primary healthcare. Specifically, we are looking at whether using in-person and technology-based support interventions...

miLINC: MDR-TB South Africa - Patient Linkage to and Retention in Care

Post Date:

2014-10-06

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Mycobacterium tuberculosis (TB) remains the leading cause of death among persons living with human immunodeficiency virus and acquired immunodeficiency syndrome (HIV/AIDS) in southern Africa. Drug-resistant TB remains a growing threat to public health despite advances made in diagnosis and...

Cohort for Tuberculosis Research by the Indo-US Medical Partnership (C-TRIUMPH)

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2013-09-28

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NIRT

Collaboratively funded by the US NIH, India’s Department of Biotechnology [DBT], and Indian Council of Medical Research, the Cohort for TB Research by the Indo-US Medical Partnership (C-TRIUMPH) is an Indo-US research consortium that is part of RePORT India, a countrywide consortium for TB research...

Community Home Based India Prevention of Mother to Child Transmission of HIV (COMBIND)

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2013-09-02

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This study ended May 14, 2019. CCGHE is assessing whether equipping Community Health Workers with mobile health technology and involving them in technology training and personal empowerment seminars can help prevent mother-to-child...

Impact of Diabetes on TB Treatment Outcomes

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2013-02-01

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Clinical Sites:

DY Patil

CCGHE, the JHU Center for TB Research and BJGMC have been awarded a $2.5 million dollar NIH grant (2013-2018) to conduct a study to evaluate treatment outcomes among Indian patients with both diabetes mellitus and active TB. This study is assessing the prevalence of impaired glucose or frank...

Feasibility and Acceptability of Smartphone-Based Ecological Momentary Assessment of Alcohol Use Among African American Men Who Have Sex With Men in Baltimore

Post Date:

2013-01-01

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This study provides evidence to support the feasibility and acceptability of using Ecological Momentary Assessment (EMA ) methods for collecting data on alcohol use among African American men who have sex with men living in urban settings. These data provide the basis for future studies of EMA-...

ONCOGRID: An mHealth Approach to Prevention and Early Diagnosis of Oral Cancer in Rural South India

Post Date:

2012-11-01

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This study ended February 7, 2017. The Indian sub-continent is burdened with 80% of the world’s patients with oral cancer, and delay in oral cancer diagnosis is one of the major problems that leads to poor treatment outcomes (V. Shanta, R. Swaminathan, R. Rama. Cancer Control 2013). Current...

Analysis of Data Collected from the Evaluation of Community-Based Education, Research and Service (COBERS)

Post Date:

2012-06-12

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This effort ended in June 2015. Makerere University College of Health Sciences (MakCHS), the Medical Schools at Gulu University (GU), Mbarara University of Science and Technology (MUST), Kampala International University (KIU) and Busitema University (BU) came together with Johns Hopkins University...

DOmestic Violence Enhanced Home Visitation and Smart Phones (DOVE)

Post Date:

2012-01-01

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This effort ended in 2017. The major challenge of early prenatal nurse home visitation programs is to accurately identify abused women. The DOVE study aims to improve maternal health and increase the use of a safety plan and community resources by using an emocha ®...

PreventionRx Study: Home-based Counseling and Testing in Uganda

Post Date:

2010-10-21

Countries:

This study was terminated August 29, 2014. A ‘platform’ for evaluating combination HIV prevention & care-HIV counseling & testing is essential to optimize HIV services. In collaboration with the University of Washington and the Integrated Community Based Initiatives (ICOBI) NGO in Uganda,...

Real-world implementation of video-observed therapy in an urban TB program in the United States

Post Date:

2021-08-02

Publication:

Int J Tuberc Lung Dis

Video directly observed therapy (vDOT) was introduced to increase flexibility and meet patient-specific needs for TB treatment.

A mobile health-facilitated behavioral intervention for community health workers improves exclusive breastfeeding and early infant HIV diagnosis in India: A cluster randomized trial

Post Date:

2020-07-03

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Publication:

Journal of the International AIDS Society

When community health workers used a mobile health intervention with HIV+ women to deliver care, there was a higher uptake of exclusive breastfeeding at two months and early infant HIV diagnosis at six weeks

Randomized trial of online, interactive decision-support versus guidelines for HIV treatment selection by trainees

Post Date:

2020-03-25

Publication:

Clinical Infectious Diseases

CID: Trainees using HIV-ASSIST were significantly more likely to choose appropriate ART regimens compared to those using guidelines alone.

Development and validation of HIV-ASSIST, an online, educational, clinical decision support tool to guide patient-centered ARV regimen selection

Post Date:

2019-10-01

Publication:

Journal of Acquired Immune Deficiency Syndromes

Maunank Shah and colleagues invented HIV-ASSIST, an online decision-making tool that helps clinicians determine what antiretroviral therapies will best meet the needs of individual HIV patients. This paper in JAIDS discusses what they found in testing the tool's validity.

Evaluation of miLINC to shorten time to treatment for rifampicin-resistant Mycobacterium tuberculosis

Post Date:

2019-09-01

Publication:

The International Journal of Tuberculosis and Lung Disease

A suite of mobile health applications shows promise for linking more drug-resisitant TB patients to care and in less time.

Use of smartphone-based video Directly Observed Therapy (vDOT) in tuberculosis care: Single-arm, prospective feasibility study

Post Date:

2019-08-30

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DY Patil

Publication:

Journal of Medical Internet Research

Video-based monitoring is increasingly used as an efficient and low cost alternative to in-person observation and monitoring of TB patients. It showed promise in the high TB setting of India, too.

HIV-ASSIST

Post Date:

2019-07-16

Publication:

HIVSpecialist

HIVSpecialist: Dr. Maunank Shah and colleagues chronicle the development of HIV-ASSIST, a tool to help guide selections for patient-centered antiretroviral therapy.

Mobile phone access and comfort: implications for HIV and tuberculosis care in India and South Africa.

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2019-07-01

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Publication:

International Journal of Tuberculosis and Lung Disease

SETTING: India and South Africa shoulder the greatest burden of tuberculosis (TB) and human immunodeficiency virus (HIV) infection respectively, but care retention is suboptimal. OBJECTIVE: We conducted a study in Pune, India, and Matlosana, South Africa ...

Advancing Patient-Centered Care in Tuberculosis Management: A Mixed-Methods Appraisal of Video Directly Observed Therapy

Post Date:

2019-06-25

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Publication:

Open Forum Infectious Diseases

OFID : Study compared directly-observed therapy with video-based observed therapy using the emocha mobile health platform

Users beware! Biological variation in complete blood counts over short time intervals

Post Date:

2019-05-29

Publication:

BMJ Evidence Based Medicine

New publication in BMJ Evidence Based Medicine looks at CBC count variations in blood drawn over a short time period

¡Vive!: Designing an intervention to improve timely HIV diagnosis among Latino immigrant men

Post Date:

2018-01-23

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Publication:

Progress in Community Health Partnerships

Background: Latinos, particularly immigrant men, are more likely to present late to care for human immunodeficiency virus (HIV) infection. Objectives: This manuscript describes the development of ¡Sólo Se Vive Una Vez! (¡Vive!) (You Only Live Once), a multilevel (...

The use of clinical decision support in reducing diagnosis of and treatment of asymptomatic bacteriuria

Post Date:

2017-12-06

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Publication:

Journal of Hospital Medicine

Clinical decision support embedded within the electronic health record is a potential antibiotic stewardship strategy for hospitalized patients.

Impact of a community health worker HIV treatment and prevention intervention in an HIV hotspot fishing community in Rakai, Uganda (mLAKE): study protocol for a randomized controlled trial

Post Date:

2017-10-23

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Publication:

Trials

Abstract Background: Effective yet practical strategies are needed to increase engagement in HIV treatment and prevention services, particularly in high-HIV-prevalence hotspots. We designed a community-based intervention called "Health Scouts" to promote uptake and adherence to...

Design and implementation of a community health worker HIV treatment and prevention intervention in an HIV hot spot fishing community in Rakai, Uganda

Post Date:

2017-05-22

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Publication:

Journal of the International Association of Providers of AIDS Care

Abstract Innovative approaches are needed to increase engagement in HIV treatment and prevention services, particularly in HIV hot spots. Here, we detail our design, training approach, and early implementation experiences of a community-based HIV intervention called "health scouts." The...

¡Sólo se vive una vez! (you only live once): a pilot evaluation of individually tailored video modules aiming to increase HIV testing among foreign-born Latino men

Post Date:

2017-02-01

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Publication:

Journal of Acquired Immune Deficiency Syndromes

BACKGROUND: Although Latinos living in the United States are disproportionately affected by HIV, the development, implementation, and evaluation of HIV prevention, testing, and linkage to care interventions lag behind efforts occurring in other communities. To address...

Ecological momentary assessment of illicit drug use compared to biological and self-reported methods

Post Date:

2016-03-15

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Publication:

Journal of Medical Internet Research

Background: The use of mHealth methods for capturing illicit drug use and associated behaviors have become more widely used in research settings, yet there is little research as to how valid these methods are compared to known measures of capturing and quantifying drug use. ...

RePORT International: advancing tuberculosis biomarker research through global collaboration

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2015-10-15

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Publication:

Clinical Infectious Diseases

Progress in tuberculosis clinical research is hampered by a lack of reliable biomarkers that predict progression from latent to active tuberculosis, and subsequent cure, relapse, or failure. Regional Prospective Observational Research for Tuberculosis (RePORT) International represents a...

GETHealth Summit Report—2014, Conference Proceedings

Post Date:

2015-07-08

The GETHealth Summit brought together healthcare professionals, representatives from the technology and education sectors, academic researchers, global health experts from backgrounds including non-governmental organisations to government. This diverse group of delegates were brought together to...

Feasibility and acceptability of smartphone-based ecological momentary assessment of alcohol use among African American men who have sex with men in Baltimore

Post Date:

2015-06-17

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Publication:

Journal of Medical Internet Research

Background: Alcohol use is a risk factor for the acquisition of human immunodeficiency virus (HIV) among African American men who havesex with men (MSM). Mobile phone-based ecological momentary assessments (EMA) could minimize bias due to retrospective recall and thus provide a better...

Utilizing mHealth methods to identify patterns of high risk illicit drug use

Post Date:

2015-06-01

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Publication:

Drug and Alcohol Dependence

Introduction: We assessed patterns of illicit drug use using mobile health (mHealth) methods and subsequent health care indicators among drug users in Baltimore, MD. Methods: Participants of the EXposure Assessment in Current Time (EXACT) study were provided...

Randomized trial of HIV-ASSIST versus guidelines for ART selection by trainees

Post Date:

2020-03-10

Countries:

Ramirez J, Maddali M, Nematollahi S, Li JZ, Shah M. Randomized trial of HIV-ASSIST versus guidelines for ART selection by trainees. Presented at: CROI 2020. Boston, MA: March 8-11, 2020.

An mHealth CHW intervention trials in an HIV hyperendemic community in Rakai, Uganda

Post Date:

2020-03-09

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Chang LW , Mbabali I, Kong X, Amico R, Kennedy CE, Nalugoda F, Anok A, Serwadda D, Ssekasanvu J, Quinn TC, Reynolds SJ, Gray RH, Wawer M, Hutton H, Nakigozi G. An mHealth CHW intervention trials in an HIV hyperendemic community in Rakai, Uganda. Presented at: CROI 2020. Boston, MA; March 8-11, 2020.

mobile Health (mHealth) strategies to strengthen CHW impact.

Post Date:

2019-09-16

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Chang L. mobile Health (mHealth) strategies to strengthen CHW impact. Strengthening the Impact of Community Health Workers on HIV Care and Viral Suppression in the US. Bethesda, MD. September 16, 2019.

Mobile Phone Access and Comfort: Implications for HIV and Tuberculosis Care in India and South Africa

Post Date:

2018-10-04

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Clinical Sites:

Cox SN , Elf J, Lokhande R, Ogale YP, DiAndreth L, Dupuis E, Milovanovic M, Mpongose N, Martinson N, Mave V, Suryavanshi N, Gupta A, Golub JE, Mathad JS. Mobile Phone Access and Comfort: Implications for HIV and Tuberculosis Care in India and South Africa. I DSA. IDWeek 2018. San Francisco, CA,...

Mobile Health and Behavioral PMTCT Intervention among Community Health Workers Improves Exclusive Breastfeeding and Early Infant Diagnosis in India: A Cluster Randomized Trial

Post Date:

2018-07-24

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Clinical Sites:

Suryavanshi N, Kadam A, Hegde A, Sivalenka S, Kumar VS, McKenzie-White J, Kanade S, Gupta A, Bollinger RC, Shankar A, Gupte N, Mave V. Mobile Health and Behavioral PMTCT Intervention among Community Health Workers Improves Exclusive Breastfeeding and Early Infant Diagnosis in India: A Cluster...

Opportunities, Challenges and Implications of m-Health Oral Cancer Screening for HIV-positive Individuals in India

Post Date:

2018-07-23

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Clinical Sites:

Joshi S, Chandanwale A, Sangle S, Marbaniang I , Khaire S, Thakur R, Gupta A, Chigurupati R, Mave V. Opportunities, Challenges and Implications of m-Health Oral Cancer Screening for HIV-positive Individuals in India. AIDS 2018. Amsterdam, The Netherlands. July 23-27, 2018.

How Americans Benefit from Global Health Research

Post Date:

2017-05-25

Countries:

Bollinger, R. How Americans Benefit from Global Health Research. The Fogarty International Center: How Americans Benefit from Global Health Research Webinar, Research!America. Washington, DC.

mHealth in medicine: A Hopkins-Focused Perspective

Post Date:

2017-02-24

Chang, L. mHealth in medicine: A Hopkins-Focused Perspective. Digital Health Day. Johns Hopkins University. Baltimore, MD.

Characteristics Associated with Mobile Phone Access among Tuberculosis Patents in Pune, India

Post Date:

2016-12-04

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Ogale YP , Elf JL, Lokhande R, Mave V, Roy S, Gupta A, Golub J, Mathad J. Characteristics Associated with Mobile Phone Access among Tuberculosis Patents in Pune, India. 46th Union World Conference on Lung Health. International Union for Tuberculosis and Lung Disease. Cape Town, South Africa.

Outreach Workers in the Prevention of Mother to Child Transmission of HIV (PMTCT) Programme in India: Challenges and Opportunities

Post Date:

2016-07-21

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Clinical Sites:

Suryavanshi N , Mave V, Kadam A, Kanade S, Sivalenka S, Sampath K, Harve P, Gupta RS, Hegde A, McKenzie-White J, Gupte N, Gupta A, Bollinger RC, Shankar AV. Outreach Workers in the Prevention of Mother to Child Transmission of HIV (PMTCT) Programme in India: Challenges and Opportunities. 21st...

A Cluster-Randomized Trial to Promote Combination HIV Prevention Using M-health-Supported CHWs in a High-Prevalence Fishing Community: Design and Baseline Characteristics of the mLAKE Trial in Rakai, Uganda

Post Date:

2016-07-21

Countries:

Chang L, Mbabali I, Kong X, Hutton H, Long A, Thomas A, Bugos E, Ssekasanvu J, Kennedy C, Amico R, Nalugoda F, Reynolds S, Quinn T, Serwadda D, Wawer M, Gray R, Nakigozi G. A Cluster-Randomized Trial to Promote Combination HIV Prevention Using M-health-Supported CHWs in a High-Prevalence Fishing...

Rapid Diagnosis, Linkage and Treatment Initiation of Patients with Drug-resistant Tuberculosis in South Africa: The miLINC Solution to Improve Access to Care

Post Date:

2016-07-20

Countries:

Farley JE , Seiguer S, Naicker M, McKenzie-White J, Greg C, Elmi M, Stevens W, Stewart-Isherwood L. Rapid Diagnosis, Linkage and Treatment Initiation of Patients with Drug-resistant Tuberculosis in South Africa: The miLINC Solution to Improve Access to Care. 21st International AIDS Conference...

Prevalence of and Risk Factors for Diabetes mellitus among Pulmonary Tuberculosis Patients in Pune, India.

Post Date:

2016-07-16

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Clinical Sites:

DY Patil

Golub, J., Gupta, A. Prevalence of and Risk Factors for Diabetes mellitus among Pulmonary Tuberculosis Patients in Pune, India. TB2016. International AIDS Society. Durban, South Africa. 2016.

Medicine as a Bridge Between the US and India

Post Date:

2016-05-21

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Gupta, A. Medicine as a Bridge Between the US and India. Indiaspora. Philadelphia, PA.

Combination HIV Prevention and HIV Incidence in a Ugandan Hotspot Fishing Community

Post Date:

2016-02-23

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Kagaayi J, Grabowski MK, Nakigozi G, Kigozi G, Nalugoda F, Ssekubugu R, Gray RH, Serwadda D, Wawer MJ, Chang L. Combination HIV Prevention and HIV Incidence in a Ugandan Hotspot Fishing Community. Conference on Retroviruses and Opportunistic Infections 2016. Boston, MA. 2016.

Novel Package of Integrated Mobile Applications Reduces Time to Treatment Initiation for Patients with MDR-TB

Post Date:

2015-12-05

Countries:

Farley J, McKenzie-White J, Seiguer S, Naicker M, Peters A, Isherwood L, Olsen F, Stevens W. Novel Package of Integrated Mobile Applications Reduces Time to Treatment Initiation for Patients with MDR-TB. The 46th Union World Conference on Lung Health. Cape Town, South Africa.

Characteristics Associated with Mobile Phone Access among TB Patients in Pune, India

Post Date:

2015-12-04

Countries:

Clinical Sites:

Ogale YP, Elf J, Lokhande R, Mave V, Roy S, Gupta A, Golub J, Mathad J. Characteristics Associated with Mobile Phone Access among TB Patients in Pune, India. The 46th Union World Conference on Lung Health. Cape Town, South Africa.

Risk Factors for Unfavorable Treatment Outcomes in DOTs-treated Pediatric TB Patients

Post Date:

2015-12-04

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Clinical Sites: