All Studies/Projects

A Prospective Study Evaluating the Role of Cryptococcal Antigen Screening among HIV-infected Adults with Low CD4 Counts

Post Date: 
2011-01-01
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This prospective observational study aimed to evaluate the burden of cryptococcal disease among approximately 200 HIV-infected adults with low CD4 cell counts in Pune, India to determine whether a Cryptococcal screening strategy should be the standard of care among patients with advanced HIV...

Brief Venue Survey of HIV Risk Places and Use of Technology in the Baltimore Latino Population

Post Date: 
2010-12-14
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This study ended December 13, 2011. In the last ten years, Baltimore City has seen a doubling in the AIDS incidence rate among Latinos. This has been paralleled by a doubling of the Baltimore Latino population over the last five years. At the Baltimore City Health Department (BCHD), Latino patients...

The Role of Vitamin D in the Development of Active Tuberculosis Disease in Young Children

Post Date: 
2010-12-09
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This study was terminated September 2014. Mycobacterium tuberculosis (MTB) results in significant morbidity and mortality worldwide, yet remains difficult to diagnose and manage, particularly in resource constrained settings. Deficiency in vitamin D, a recently recognized antimicrobial peptide, is...

P1073: Study of Immune Reconstitution Inflammatory Syndrome (IRIS) for International Sites Initiating Highly Active Antiretroviral Therapy (HAART) in Infants and Children < 72 Months of Age

Post Date: 
2010-11-15
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This study was terminated April 23, 2015. This is a multi-national study conducted in India, South Africa, and Tanzania. P1073 is a case controlled prospective, clinical, observational and pathogenesis study of HIV-infected infants and children (≥ 4 weeks to < 72 months of age) at international...

PreventionRx Study: Home-based Counseling and Testing in Uganda

Post Date: 
2010-10-21
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This study was terminated August 29, 2014. A ‘platform’ for evaluating combination HIV prevention & care-HIV counseling & testing is essential to optimize HIV services. In collaboration with the University of Washington and the Integrated Community Based Initiatives (ICOBI) NGO in Uganda,...

Retrospective Characterization of Clinical and Demographic Data of Pediatric Tuberculosis Patients Treated at BJ Medical College in Pune, India

Post Date: 
2010-06-10
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This study ended June 14, 2013.

Hospitalized Pediatric Patients with Pandemic 2009 H1N1 Influenza in India (August-November 2009)

Post Date: 
2010-04-10
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This study ended in April 2013. This was a review and collection of data from the medical records of pediatric patients who were admitted to the BJMC/Sassoon General Hospitals with H1N1 influenza during August-November 2009.

P1077FF: Formula Feeding Version of the PROMISE Study (Promoting Maternal and Infant Survival Everywhere)

Post Date: 
2010-02-02
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This multi-country trial is being conducted in India, Malawi, South Africa, Tanzania, Uganda, Zambia, and Zimbabwe. 1077FF is a randomized strategy trial, which is part of the PROMISE studies (1077BF, 1077FF, P1084s, and 1077HS). The Promoting Maternal and Infant Survival Everywhere (PROMISE)...

P1077BF: Breastfeeding Version of the PROMISE Study (Promoting Maternal and Infant Survival Everywhere)

Post Date: 
2010-02-02
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This multi-country trial is being conducted in India, Malawi, South Africa, Tanzania, Uganda, Zambia, and Zimbabwe. 1077BF is a randomized strategy trial, which is part of the PROMISE studies (1077BF, 1077FF, P1084s, and 1077HS). The Promoting Maternal and Infant Survival Everywhere (PROMISE)...

Impact of Malnutrition on HIV Treatment Failure in Resource-limited Settings

Post Date: 
2010-01-01
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Highly active antiretroviral therapy (HAART) has reduced morbidity and mortality among HIV-infected persons worldwide. However, early treatment failure (i.e. WHO stage 3 or 4 illnesses or death during the first 24 months of HAART) is more than 3-fold higher in resource limited settings (RLS) than...

Assessment of Active Tuberculosis amongst Asymptomatic HIV-infected Patients in Kakinada, India

Post Date: 
2009-07-23
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This study was conducted in 2008. Tuberculosis (TB) is a major public health threat in India and is the leading cause of morbidity and mortality amongst people living with HIV/AIDS worldwide.1 According to the WHO, India accounts for one-fifth of the global TB incident cases, with over 1.9 million...

A5225: Phase I/II Dose-Finding Study of High-Dose Fluconazole Treatment in AIDS-Associated Cryptococcal Meningitis

Post Date: 
2009-04-22
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This trial was terminated in March 2015. This multi-country stidy was conducted in India, Kenyam Peru, South Africa, Thailand, Uganda, United States, and Zimbabwe. A5225/HiFLAC is a Phase I/II dose escalation and validation study of the safety, tolerability, and therapeutic effect of an induction-...

A5253: Sensitivity and Specificity of Mycobacterium Tuberculosis Screening and Diagnostics in HIV-Infected Individuals

Post Date: 
2009-03-19
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This study was terminated October 15, 2014. An estimated 3 million HIV-infected individuals will enter programs for antiretroviral (ARV) treatment in the coming year, with projected rates of requirement for ARV therapy extending to more than 10 million in sub-Saharan Africa, southeastern Asia, and...

Evaluation of the Impact of Distance Learning For Expanding Capacity for Clinical Research in India

Post Date: 
2009-02-13
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This study ended in March 2012. The Office of AIDS Research has initiated a comprehensive program to expand clinical research capacity in India. This program has utilized a number of platforms for providing research training, including intensive in-country workshops and conferences. These programs...

P1070: Dose-Finding and Pharmacogenetic Study of Efavirenz in HIV-Infected and HIV/TB Co-Infected Infants and Children ≥ 3 Months to < 36 Months of Age

Post Date: 
2008-12-05
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This study ended March 10, 2015. This multi-country trial was conducted in India, South Africa, Tanzania, Uganda, Zambia, and Zimbabwe. Efavirenz (EFV) is an anti-HIV medicine that is commonly used to treat HIV infection in adults and children older than 3 years of age. This study is being...

EXposure Assessment in Current Time (EXACT) study

Post Date: 
2008-11-01
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Injection drug users (IDUs) are a marginalized population with substantial disparities in healthcare outcomes, especially among the HIV-infected IDU population. The EXACT study, which ended in 2013, was designed to optimize time to antiretroviral treatment (ART) initiation and retention-in-care...

The Presentation and Disease Progression of HIV Infection Among Indian Children

Post Date: 
2008-09-22
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This study was terminated July 24, 2010.

Cryptococcal Meningitis among Hospitalized HIV Patients in India (June 2008–June 2010)

Post Date: 
2008-06-30
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This study was terminated in 2016. Cryptococcal meningitis secondary to HIV infection is one of the leading causes of mortality from infectious agents worldwide. Recent estimates suggest close to a million infections annually and over six hundred thousand deaths every year. South and Southeast Asia...

Immunomodulatory Properties of BCG: Implications for MTCT

Post Date: 
2008-06-01
To evaluate the immune activating properties of BCG vaccination in neonatal CD4 cells and test the hypothesis that neonatal BCG vaccination leads to activation of immune response that may increase the susceptibility to HIV infection in breast-fed infants of HIV-positive mothers.

HIV Latino Outreach Program, Baltimore City Health Department

Post Date: 
2008-01-01
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Dr. Kathleen Page founded and directs the Baltimore City Health Department’s HIV Latino Outreach Program, which provides more than 1000 HIV tests per year to Baltimore's Latino community, and provides linkages to care services for those testing positive.

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