Presentations

Mathad JS , Savic RM, Britto P, Wiesner L, Townley E, Chakhtoura N, Bradford S, Patil S, Vhembo T, Lespinasse D, Langat D, Werarak P, Kamthunzi P, Gupta A, Dooley KE. Rifapentine pharmacokinetics and safety in pregnant women with and without HIV on 3HP. Presented at: CROI 2020. Boston, MA; March 8-...

Rapidly declining HIV incidence among men and women in Rakai, Uganda

Post Date:

2020-03-11

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Nakigozi G , Chang LW, Reynolds SJ, Nalugoda F, Kigozi G, Quinn TC, Gray RH, Kisakye A, Ndyanabo A, Ssekubugu R, Serwadda D, Wawer M, Kayaayi J, Grabowski MK, for the Rakai Health Sciences Program. Rapidly declining HIV incidence among men and women in Rakai, Uganda. Presented at: CROI 2020. Boston...

Trends in linkage into care after “Test and Start” among adolescents and young adults

Post Date:

2020-03-11

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Kigozi DS , Kreniske P, Chen I, Nalugoda F, Hoffman S, Kigozi G, Nakigozi G, Ssekubugu R, Kankaka E, Gray RH, Wawer M, Chang LW, Reynolds SJ, Lualo T, Kagaayi J. Trends in linkage into care after “Test and Start” among adolescents and young adults. Presented at: CROI 2020. Boston, MA; March 8-11,...

Early bactericidal activity of meropenem (+ Amox/Clav) with and without rifampin for TB

Post Date:

2020-03-10

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De Jager V, Abufathi AA, Feyt H, Gupte N, Vanker N, Barnes G, van Brakel E, Nuermberger E, Dorman SE, Svensson EM, Diacon AH, Dooley KE. Early bactericidal activity of meropenem (+ Amox/Clav) with and without rifampin for TB. Presented at: CROI 2020. Boston, Massachusetts. March 8-11, 2020.

Effect of rifamycins on pretomanid exposure in patients with pulmonary TB

Post Date:

2020-03-10

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Abdelwahab MT , Ignatius E, Denti P, Dooley KE, Gupte N, Dawson R, Barnes G, Narunsky K, Hendricks B. Effect of rifamycins on pretomanid exposure in patients with pulmonary TB. (ID 3688). Presented at: CROI 2020. Boston, Massachusetts. March 8-11, 2020.

Indeterminate HIV rapid-test results: Outcomes and risk factors

Post Date:

2020-03-10

Countries:

Mwinnyaa G , Grabkowski MK, Gray RH, Wawer M, Chang LW, Ssekasanvu J, Kagaayi J, Kigozi G, Galiwango RM, Ndyanabo A, Serwadda D, Quinn TC, Reynolds SJ, Laeyendecker O for the Rakai Community Cohort Study. Indeterminate HIV rapid-test results: Outcomes and risk factors. Presented at: CROI 2020...

Long-term effectiveness of voluntary medical male circumcision for HIV prevention

Post Date:

2020-03-10

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Loevinsohn G , Kigozi G, Kagaayi J, Nalugoda F, Chang LW, Serwadda D, Reynolds SJ, Nakigozi G, Ssekubugu R, Wawer M, Tobian A, Gray RH, Grabowski MK for the Rakai Sciences Program. Long-term effectiveness of voluntary medical male circumcision for HIV prevention. Presented at: CROI 2020. Boston, MA...

“Stylish Man” cluster RCT to increase male circumcision for adult men ≥ 19, Uganda

Post Date:

2020-03-10

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Wawer M , Kigozi G, Mugamba S, Zikusooka A, Kagaayi J, Serwadda D, Ndyanabo A, Ssekubugu R, Sseasanvu J, Chang LW, Gray RH. “Stylish Man” cluster RCT to increase male circumcision for adult men ≥ 19, Uganda. Presented at: CROI 2020. Boston, MA; March 8-11, 2020.

Randomized trial of HIV-ASSIST versus guidelines for ART selection by trainees

Post Date:

2020-03-10

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Ramirez J, Maddali M, Nematollahi S, Li JZ, Shah M. Randomized trial of HIV-ASSIST versus guidelines for ART selection by trainees. Presented at: CROI 2020. Boston, MA: March 8-11, 2020.

Waxing and waning HIV risk: Dynamics of PrEP eligibility in Rakai, Uganda

Post Date:

2020-03-09

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Ssempijja V, Ssekubugu R, Kigozi G, Kakigozi G, Kagaayi J, Lutalo T, Ndyanabo A, Ekstrom AM, Serwadda D, Quinn TC, Gray RH, Wawer M, Chang LW, Reynolds SJ. Waxing and waning HIV risk: Dynamics of PrEP eligibility in Rakai, Uganda. Presented at: CROI 2020. Boston, MA; March 8-11, 2020.

Factors associated with gestational diabetes in HIV+ and HIV- women in Pune, India

Post Date:

2020-03-09

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Chebrolu P , Alexander M, Bhosale R, Naik S, Patil N, Gupta A, Mathad J. Factors associated with gestational diabetes in HIV+ and HIV- women in Pune, India. Presented at: CROI 2020. Boston, Massachusetts. March 8-11, 2020.

An mHealth CHW intervention trials in an HIV hyperendemic community in Rakai, Uganda

Post Date:

2020-03-09

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Chang LW , Mbabali I, Kong X, Amico R, Kennedy CE, Nalugoda F, Anok A, Serwadda D, Ssekasanvu J, Quinn TC, Reynolds SJ, Gray RH, Wawer M, Hutton H, Nakigozi G. An mHealth CHW intervention trials in an HIV hyperendemic community in Rakai, Uganda. Presented at: CROI 2020. Boston, MA; March 8-11, 2020.

Geographic and Individual Risk Factors for TB or Death in the Brief-TB Trial (A5279)

Post Date:

2020-03-09

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Riviere C , Juste MAJ, Ramchandani R, Gupta A, Benson CA, Masheto G, Supparatpinyo K, Mohapi L, da Silva Escada RO, Mngqibisa R, Kanyama C, Langat D, Swindells S, Chaisson RE, for the A5279/BRIEF TB Study Team. Geographic and Individual Risk Factors for TB or Death in the Brief-TB Trial (A5279)...

Adjusted analysis of effect of IPT on adverse pregnancy outcomes in women with HIV

Post Date:

2020-03-09

Clinical Sites:

Theron G , Chakhtoura N, Montepiedra G, Aaron L, Jean-Phillipe P, Weinberg A, McCarthy K, Nematadzira T, Masheto G, Chipato T, Onyango-Makumbi C, Gupta A, the IMPAACTP1078 Team. Adjusted analysis of effect of IPT on adverse pregnancy outcomes in women with HIV. Presented at: CROI 2020. Boston,...

Population-level HIV viral load varies by gender, age, and location in Rakai, Uganda

Post Date:

2020-03-09

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Kyle I , Kagaagi J, Kigozi G, Nakigozi G, Ssekbugu R, Nalugoda F, Grabowski MK, Chang LW, Wawer M, Serwadda D, Gray RH, Quinn T, Reynolds SJ, Rattman O for the Rakai Health Sciences Program. Population-level HIV viral load varies by gender, age, and location in Rakai, Uganda. Presented at: CROI...

Tuberculosis preventive therapy should be considered for all household contacts of pulmonary TB patients in India

Post Date:

2020-02-07

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Paradkar M, Chandrasekara P, Jain D, Shivakumar SVBY, Thiruvengadan K, Gupte AN, Thomas B, Kinikar A, Sekar K, Bharadwaj R, Dolla CK, Gaikwad S, Elilarasi S, Lokhande R, Reddy D, Murali L, Kulkarni V, Pradhan N, Hanna LE, Pattabiraman S, Kohli R, Nayagam R, Suryavanshi N, Shrinivasa BM, Cox SR,...

Female tuberculosis (TB) patients with stigma are at increased risk of persistent depression: time to integrate mental health screening into TB care

Post Date:

2019-11-20

Clinical Sites:

Suryavanshi N . Female tuberculosis (TB) patients with stigma are at increased risk of persistent depression: time to integrate mental health screening into TB care. Poster presentation. 50th Union World Conference on Lung Health. Hyderabad, India. October 30-November 2, 2019.

Confronting the crisis: emerging research in maternal-child TB

Post Date:

2019-11-02

Mathad J . Symposium Chair. Confronting the crisis: emerging research in maternal-child TB. 50th Union World Conference on Lung Health. Hyderabad, India. October 30-November 2, 2019.

The crisis in maternal TB: a case-based discussion of research gaps

Post Date:

2019-11-02

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Naik SN . The crisis in maternal TB: a case-based discussion of research gaps. Speaker. Confronting the crisis: emerging research in maternal-child TB Symposium. 50th Union World Conference on Lung Health. Hyderabad, India. October 30-November 2, 2019.

BWI CTU: Baltimore-Washington-India Clinical Trials Unit

Post Date:

2007-02-02

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Comprising clinical trial sites at Johns Hopkins Medicine in Baltimore, Whitman Walker Health in Washington, DC, and the BJGMC-CCGHE collaboration in Pune, India, the Baltimore-Washington-India Clinical Trials Unit (BWI-CTU) is one of only 25 international HIV/TB clinical trial sites funded by the...

BJGMC-JHU Fogarty HIV-TB Training Program

Post Date:

2007-01-01

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Funded by the Fogarty International Center at the National Institutes of Health, the JHU Fogarty program has nearly 20 years of success with providing training, professional development, and mentorship to clinicians and scientists in low and middle income countries. CCGHE's latest efforts in this...

Impact of Malnutrition on HIV Treatment Failure in Resource-limited Settings

Post Date:

2009-04-02

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This study, NWCS 319, was terminated August 20, 2019. Highly active antiretroviral therapy (HAART) has reduced morbidity and mortality among HIV-infected persons worldwide. However, early treatment failure (i.e. WHO stage 3 or 4 illnesses or death during the first 24 months of HAART) is more than 3...

Cohort for Tuberculosis Research by the Indo-US Medical Partnership (C-TRIUMPH)

Post Date:

2013-09-28

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Collaboratively funded by the US NIH, India’s Department of Biotechnology [DBT], and Indian Council of Medical Research, the Cohort for TB Research by the Indo-US Medical Partnership (C-TRIUMPH) is an Indo-US research consortium that is part of RePORT India, a countrywide consortium for TB research...

C-TRIUMPH Pilot Study: Burden and Risk Factors for Drug-resistant Tuberculosis in Pune, India

Post Date:

2012-05-29

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This pilot study ended in April 2015. Drug resistant TB (MDR-TB and XDR-TB) is increasing worldwide. Although 20% of all global TB cases occur in India, current estimates of the burden of MDR-TB in India are limited. A well-characterized TB clinical cohort, household cohort and control cohort would...

Diagnosis of Active Tuberculosis in HIV-infected and Uninfected Young Children in India

Post Date:

2012-07-24

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Tuberculosis (TB) is the most common cause of morbidity/mortality in HIV-infected individuals in India. India has the world's highest burden of HIV and TB, and since children acquire HIV/TB from their caregivers, active TB is highly prevalent (14-67.5%) among HIV-infected young children in India...

Hair Concentrations of Anti-tuberculosis Drugs Among HIV-infected and Uninfected Children in India

Post Date:

2013-05-07

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This study was terminated May 15, 2017. In the developing world, tuberculosis (TB) is a major cause of mortality among HIV-infected children, a population where measuring treatment adherence and drug levels is difficult. We propose an innovative therapeutic drug monitoring (TDM) tool that measures...

A Prospective Study Evaluating the Role of Cryptococcal Antigen Screening among HIV-infected Adults with Low CD4 Counts

Post Date:

2011-01-01

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This prospective observational study aimed to evaluate the burden of cryptococcal disease among approximately 200 HIV-infected adults with low CD4 cell counts in Pune, India to determine whether a Cryptococcal screening strategy should be the standard of care among patients with advanced HIV...

Mother-to-Child Transmission (MTCT) of HIV: India SWEN Study

Post Date:

2002-06-07

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This study was officially terminated August 2018. Primary and secondary analyses of the India SWEN study, an NIH-funded phase III randomized controlled trial of an extended nevirapine prophylaxis regimen among 783 HIV-infected pregnant women and their breastfed infants in Pune, India.

Assessing the Association of Indoor Air Pollution with Tuberculosis in Adult Women and Children under 5 Years of Age

Post Date:

2013-09-15

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This study is conducted the Cohort for Tuberculosis Research by the Indo-US Medical Partnership (C-TRIUMPH) under the Regional Prospective Observational Research for Tuberculosis (RePORT) Network, an international TB consortium. Addressing social and environmental risk factors contributing to TB...

Diagnosis of Tuberculosis Infection and Th1 Immune Response in Pregnant Women in India

Post Date:

2014-09-01

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This study was terminated April 16, 2018. Tuberculosis (TB) disease is a major cause of mortality among Indian women of reproductive age; approximately 20-50% of women in India are latently infected with Mycobacterium tuberculosis (MTB). Due to immune changes of pregnancy, women are particularly at...

Tuberculosis Noon Conference

Post Date:

2013-10-24

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This effort ended in 2015. As part of the BJGMC-Johns Hopkins India Fogarty Training Program, from 2013-2015 CCGHE hosted the live Tuberculosis Noon Conference webcast. Led by Drs. Maunank Shah, Jonathan Golub, and Richard Chaisson, these webcast meetings brought together Johns Hopkins TB...

TB Case Conference

Post Date:

2013-02-25

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CCGHE broadcasts live TB Case Conferences and provides a global audience with open access to all live and archived webcasts via the CCGHE website. Hosted by Dr. Maunank Shah (Johns Hopkins), this case-based conference serves as a forum where clinicians caring for individuals with active TB can...

ONCOGRID: An mHealth Approach to Prevention and Early Diagnosis of Oral Cancer in Rural South India

Post Date:

2012-11-01

Countries:

Democratic Republic of Congo

This study ended February 7, 2017. The Indian sub-continent is burdened with 80% of the world’s patients with oral cancer, and delay in oral cancer diagnosis is one of the major problems that leads to poor treatment outcomes (V. Shanta, R. Swaminathan, R. Rama. Cancer Control 2013). Current...

Johns Hopkins Infectious Diseases (ID) Grand Rounds

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CCGHE broadcasts monthly Johns Hopkins (JH) Infectious Diseases (ID) Grand Rounds to centers in the Democratic Republic of Congo as an initial inroad to improve clinical education. ID Grand Rounds is an educational conference where JH faculty and trainees discuss clinical cases from the JH Hospital...

EXposure Assessment in Current Time (EXACT) study

Post Date:

2008-11-01

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Injection drug users (IDUs) are a marginalized population with substantial disparities in healthcare outcomes, especially among the HIV-infected IDU population. The EXACT study, which ended in 2013, was designed to optimize time to antiretroviral treatment (ART) initiation and retention-in-care...

Technology-enhanced Peer Navigation to Improve Injection Drug User (IDU) Engagement in HIV Care

Post Date:

2000-01-01

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This study is evaluating an mHealth-enhanced peer navigation intervention for improving retention-in-care and adherence to antiretroviral therapy (ART) for out-of-care, HIV-infected injection drug users (IDUs). The CCGHE-developed emocha® is assisting peer navigators (former IDUs successfully...

DOmestic Violence Enhanced Home Visitation and Smart Phones (DOVE)

Post Date:

2012-01-01

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This effort ended in 2017. The major challenge of early prenatal nurse home visitation programs is to accurately identify abused women. The DOVE study aims to improve maternal health and increase the use of a safety plan and community resources by using an emocha ®...

PreventionRx Study: Home-based Counseling and Testing in Uganda

Post Date:

2010-10-21

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