Presentations

A Cluster-Randomized Trial to Promote Combination HIV Prevention Using M-health-Supported CHWs in a High-Prevalence Fishing Community: Design and Baseline Characteristics of the mLAKE Trial in Rakai, Uganda

Post Date: 
2016-07-21
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Countries: 
Chang L, Mbabali I, Kong X, Hutton H, Long A, Thomas A, Bugos E, Ssekasanvu J, Kennedy C, Amico R, Nalugoda F, Reynolds S, Quinn T, Serwadda D, Wawer M, Gray R, Nakigozi G. A Cluster-Randomized Trial to Promote Combination HIV Prevention Using M-health-Supported CHWs in a High-Prevalence Fishing...

Rapid Diagnosis, Linkage and Treatment Initiation of Patients with Drug-resistant Tuberculosis in South Africa: The miLINC Solution to Improve Access to Care

Post Date: 
2016-07-20
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Countries: 
Farley JE , Seiguer S, Naicker M, McKenzie-White J, Greg C, Elmi M, Stevens W, Stewart-Isherwood L. Rapid Diagnosis, Linkage and Treatment Initiation of Patients with Drug-resistant Tuberculosis in South Africa: The miLINC Solution to Improve Access to Care. 21st International AIDS Conference...

High Risk for Loss to Follow-Up among Adolescents Living with HIV in Pune, India

Post Date: 
2016-07-19
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Countries: 
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Clinical Sites: 
Nimkar S , Valvi C, Khadse S, Kadam D, Kinikar A, Marbaniang I, Rewari BB, Chandanwale A, Suryavanshi N, Patil S, Nevrekar N, Raichur P, Gupta A, Mave V. High Risk for Loss to Follow-Up among Adolescents Living with HIV in Pune, India. 21st International AIDS Conference. International AIDS Society...

Host Factors Associated with Poor Respiratory Health-related Quality of Life in Pulmonary Tuberculosis

Post Date: 
2016-07-17
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Clinical Sites: 
Gupte A , Meshram S, Selvaraju S, Gupte N, Shivakumar SVBY, Paradkar M, Kohli R, Theruvengadam K, Suryavanshi N, Chandrasekaran P, Mave V, Swaminathan S, Salvi S, Checkley, W, Golub J, Gupta A. Host Factors Associated with Poor Respiratory Health-related Quality of Life in Pulmonary Tuberculosis...

A5300/I2003: Feasibility of Identifying, Recruiting, and Characterizing Adult MDR TB Index Cases and their Adult and Child Household Contacts on Four Continents

Post Date: 
2016-07-17
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Clinical Sites: 
Swindells S , Kim S, Gupta A, Hesseling AC, Shah S, Johnson D, Harrington M, Suryavanshi N, Sanchez J, Dawson R, Naini L, Jones L, Hughes M, Churchyard G, for ACTG/IMPAACT. A5300/I2003: Feasibility of Identifying, Recruiting, and Characterizing Adult MDR TB Index Cases and their Adult and Child...

Prevalence of and Risk Factors for Diabetes mellitus among Pulmonary Tuberculosis Patients in Pune, India.

Post Date: 
2016-07-16
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Clinical Sites: 
Golub, J., Gupta, A. Prevalence of and Risk Factors for Diabetes mellitus among Pulmonary Tuberculosis Patients in Pune, India. TB2016. International AIDS Society. Durban, South Africa. 2016.

The Association of Household Air Pollution and Tuberculosis in Women and Children in Pune, India

Post Date: 
2016-06-21
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Countries: 
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Clinical Sites: 
Elf, J. The Association of Household Air Pollution and Tuberculosis in Women and Children in Pune, India. 2016 Annual Meeting. Johns Hopkins Center for Tuberculosis Research. Baltimore, MD. 2016.

High Proportion of Extrapulmonary Tuberculosis in Baltimore City

Post Date: 
2016-06-21
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Countries: 
Chida, N. High Proportion of Extrapulmonary Tuberculosis in Baltimore City. 2016 Annual Meeting. Johns Hopkins Center for Tuberculosis Research. Baltimore, MD. 2016.

Host Factors Associated with Poor Respiratory Health-Related Quality of Life in Pulmonary TB

Post Date: 
2016-06-21
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Clinical Sites: 
Gupte, A. Host Factors Associated with Poor Respiratory Health-Related Quality of Life in Pulmonary TB. 2016 Annual Meeting. Johns Hopkins Center for Tuberculosis Research. Baltimore, MD. 2016.

Inflammation in HIV-infected Pregnant Women: Relationship with Diet, Gut Microbiome, and Preterm Birth

Post Date: 
2016-06-10
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Countries: 
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Clinical Sites: 
Shivakoti, R. Inflammation in HIV-infected Pregnant Women: Relationship with Diet, Gut Microbiome, and Preterm Birth. JHU Center for AIDS Research Annual Meeting. Baltimore, MD.

Medicine as a Bridge Between the US and India

Post Date: 
2016-05-21
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Countries: 
Gupta, A. Medicine as a Bridge Between the US and India. Indiaspora. Philadelphia, PA.

An Overview of Protecting Households on Exposure to Newly Diagnosed Index (PHOENIx) Trial

Post Date: 
2016-05-19
Gupta, A. An Overview of Protecting Households on Exposure to Newly Diagnosed Index (PHOENIx) Trial. Johns Hopkins Center for Tuberculosis Research. Baltimore, MD.

Best Practices in Antiretroviral Therapy: Managing Antiretroviral Therapy in HIV-Infected Patients with Viral Hepatitis Coinfection

Post Date: 
2016-05-18
Gupta, A. Best Practices in Antiretroviral Therapy: Managing Antiretroviral Therapy in HIV-Infected Patients with Viral Hepatitis Coinfection. Gupta A. Best Practices in Antiretroviral Therapy: Managing Antiretroviral Therapy in HIV-Infected Patients with Viral Hepatitis Coinfection. Contemporary...

Double Trouble: Managing and Preventing TB and HIV

Post Date: 
2016-04-20
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Countries: 
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Clinical Sites: 
Gupta, A. Double Trouble: Managing and Preventing TB and HIV. DY Patil University. Pune, India.

TB in HIV

Post Date: 
2016-03-25
Gupta, A. TB in HIV. New Mexico Annual HIV & HCV Conference. Albuquerque, NM.

Conducting ID Research in India and Beyond

Post Date: 
2016-03-14
Gupta, A. Conducting ID Research in India and Beyond. ID Didactic Research Forum, Johns Hopkins School of Medicine. Baltimore, MD.

Clinical, Social, and Meteorological Factors Associated with Dengue and Malaria Diagnosis in Adults in Pune, India

Post Date: 
2016-03-03
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Countries: 
Kadam D, Raichur P, Chandanwale A, Joshi S, Robinson M, Marbaniang I, Kagal A, Bharadwaj, Mave V. Clinical, Social, and Meteorological Factors Associated with Dengue and Malaria Diagnosis in Adults in Pune, India. 17th International Congress on Infectious Diseases. Hyderabad, India.

Frequent Resistant Gram Negative Rod Stool Colonization among Patients Admitted with Acute Febrile Illness in Pune, India

Post Date: 
2016-03-03
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Countries: 
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Clinical Sites: 
Bharadwaj RS, Robinson M, Marbaniang I, Kagal A, Raichur PA, Kulkami V, Balasubramanian U, Onawale P, Kanade S, Nelson G, Gupta A, Mave V. Frequent Resistant Gram Negative Rod Stool Colonization among Patients Admitted with Acute Febrile Illness in Pune, India. 17th International Congress on...

High TB Risk in HIV-Positive Patients on Second line Antiretrovirals in Pune, India

Post Date: 
2016-02-24
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Countries: 
Mave V , Kadam D, Salvi S, Basavaraj A, Joshi S, Chandanwale A, Gupte N, Bollinger RC, Gupta A. High TB Risk in HIV-Positive Patients on Second line Antiretrovirals in Pune, India. Conference on Retroviruses and Opportunistic Infections 2016. Boston, MA. 2016.

Pregnancy Intensifies the IFN-gamma Suppression of HIV in TB-infected Indian Women

Post Date: 
2016-02-24
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Clinical Sites: 
Mathad J, Bhosale R, Balasubramanian U, Deshpande P, Kanade S, Mave V, Gupta A. Pregnancy Intensifies the IFN-gamma Suppression of HIV in TB-infected Indian Women. Conference on Retroviruses and Opportunistic Infections 2016. Boston, MA. 2016.

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25-Hydroxyvitamin D insufficiency and deficiency is associated with HIV disease progression and virological failure post-antiretroviral therapy initiation in diverse multinational settings

Post Date: 
2014-07-15
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Clinical Sites: 
Publication: 
The Journal of Infectious Diseases
Background: Low 25-hydroxyvitamin D (25(OH)D) has been associated with increased HIV mortality, but prospective studies assessing treatment outcomes after combination antiretroviral therapy (cART) initiation in resource-limited settings are lacking. Methods: A case-cohort study (N = 411) was nested...

Socioeconomic determinants of mortality in HIV: evidence from a clinical cohort in Uganda

Post Date: 
2014-05-15
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Countries: 
Publication: 
Journal of Acquired Immune Deficiency Syndromes
Objective: To delineate the association between baseline socioeconomic status (SES) indicators and mortality and lost to follow-up (LTFU) in a cohort of HIV-infected individuals enrolled in antiretroviral therapy (ART) in urban Uganda. Design: Retrospective cohort study nested in an antiretroviral...

Barriers and delays in tuberculosis diagnosis and treatment services: does gender matter

Post Date: 
2014-04-28
Publication: 
Tuberculosis Research and Treatment
Background: Tuberculosis (TB) remains a global public health problem with known gender-related disparities. We reviewed the quantitative evidence for gender-related differences in accessing TB services from symptom onset to treatment initiation. Methods: Following a systematic review process, we:...

Change in Vitamin D levels occurs early after antiretroviral therapy initiation and depends on treatment regimen in resource-limited settings

Post Date: 
2014-04-21
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Clinical Sites: 
Publication: 
PLOS One
Background: Vitamin D has wide-ranging effects on the immune system, and studies suggest that low serum vitamin D levels are associated with worse clinical outcomes in HIV. Recent studies have identified an interaction between antiretrovirals used to treat HIV and reduced serum vitamin D levels,...

The evolving role of advocacy in tuberculosis

Post Date: 
2014-04-02
Publication: 
The Lancet Respiratory Medicine
Tuberculosis advocacy has changed the disease from a silent epidemic to one with many voices that seek increased political will and investment in research.1 Tuberculosis advocacy has gained strength as a mechanism to improve research, increase access to new methods to fight tuberculosis, and...

Peer Health Workers and AIDS Care in Rakai, Uganda: A mixed methods operations research evaluation of a cluster-randomized trial

Post Date: 
2011-12-15
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Countries: 
Publication: 
AIDS Patient Care and STDs
Settings with limited health care workers are challenging environments for delivery of antiretroviral therapy. One strategy to address this human resource crisis is to task shift through training selected patients as peer health workers (PHWs) to provide care to other individuals receiving...

Pregnancy differentially impacts performance of latent tuberculosis diagnostics in a high-burden setting

Post Date: 
2014-03-21
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Countries: 
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Publication: 
PLOS One
Background: Targeted screening for latent TB infection (LTBI) in vulnerable populations is a recommended TB control strategy. Pregnant women are at high risk for developing TB and likely to access healthcare, making pregnancy an important screening opportunity in developing countries. The...

Biomarkers for sepsis: a review with special attention to India

Post Date: 
2014-03-19
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Countries: 
Publication: 
BioMed Research International
Sepsis is a serious infection and still a common cause of morbidity and mortality in resource-limited settings such as India. Even when microbiologic diagnostics are available, bacteremia is only identified in a proportion of patients who present with sepsis and bloodstream infections. Biomarkers...

Maternal pneumococcal capsular IgG antibodies and transplacental transfer are lower in South Asian HIV-infected mother-infant pairs

Post Date: 
2014-03-14
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Countries: 
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Publication: 
Vaccine
Background: Our understanding of the mother-to-child transfer of serotype-specific pneumococcal antibodies is limited in non-immunized, HIV-positive women. Methods: We compared geometric mean antibody concentrations (GMCs), geometric mean transplacental cord:maternal ratios (GMRs) and proportions...

Field evaluation of PIMA point-of-care CD4 testing in Rakai, Uganda

Post Date: 
2014-03-10
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Countries: 
Publication: 
PLOS One
Objective: To assess the accuracy of PIMA Point-of-Care (POC) CD4 testing in rural Rakai, Uganda. Methods: 903 HIV positive persons attending field clinics provided a venous blood sample assessed on site using PIMA analyzers per manufacturer's specifications. The venous samples were then run on...

The role of viral introductions in sustaining community-based HIV epidemics in rural Uganda: evidence from spatial clustering, phylogenics, and egocentric transmission models

Post Date: 
2014-03-04
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Countries: 
Publication: 
PLOS One
Background: It is often assumed that local sexual networks play a dominant role in HIV spread in sub-Saharan Africa. The aim of this study was to determine the extent to which continued HIV transmission in rural communities—home to two-thirds of the African population—is driven by intra-community...

Modifiable risk factors associated with tuberculosis disease in children in Pune, India

Post Date: 
2014-02-15
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Countries: 
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Publication: 
International Journal of Tuberculosis and Lung Disease
Setting: India accounts for the largest burden of tuberculosis (TB) worldwide, with 26% of the world's cases. Objective: To assess the association between novel modifiable risk factors and TB in Indian children. Design: Cases were children aged ≤ 5 years with confirmed/probable TB based on World...

Challenges to disclosure of HIV status to perinatally infected children: a study of caregiver perspectives in Pune, India

Post Date: 
2014-06-15
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Publication: 
Journal of Pediatric Infectious Diseases
Effective guidelines around disclosure of HIV status are lacking and limited data from India reveal low rates of HIV disclosure to perinatally infected children. This study, conducted in Pune, India, attempts to understand the experiences of caregivers of perinatally infected children around the...

Impact of maternal hepatitis B virus coinfection on mother-to-child transmission of HIV

Post Date: 
2014-07-15
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Publication: 
HIV Medicine
Objectives: Despite high hepatitis B virus (HBV) endemicity in various resource-limited settings (RLSs), the impact of maternal HIV/HBV coinfection on infant health outcomes has not been defined. We aimed to assess the prevalence of HBV coinfection among HIV-infected pregnant women and its impact...

Mortality and long-term virologic outcomes in children and infants treated with lopinavir/ritonavir

Post Date: 
2013-12-15
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Countries: 
Publication: 
Pediatric Infectious Disease Journal
Background: There is scant data on young children receiving protease inhibitor-based therapy in real-life resource-limited settings and on the optimal timing of therapy among children who survive infancy. Our aim was to evaluate outcomes at the Hospital del Niño, Panama, where children have been...

Pediatric tuberculosis in young children in India: a prospective study

Post Date: 
2013-11-11
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Countries: 
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Clinical Sites: 
Publication: 
BioMed Research International
Background: India has one of the highest tuberculosis (TB) burdens globally. However, few studies have focused on TB in young children, a vulnerable population, where lack of early diagnosis results in poor outcomes. Methods: Young children (≤ 5 years) with suspected TB were prospectively enrolled...

The Exposure Assessment in current time (EXACT) study: implementation, feasibility and acceptability of real-time data collection in a community cohort of illicit drug users

Post Date: 
2013-11-06
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Countries: 
Publication: 
AIDS Research and Treatment
Objective: We describe the study design and evaluate the implementation, feasibility, and acceptability of an ecological momentary assessment (EMA) study of illicit drug users. Design. Four sequential field trials targeting observation of 30 individuals followed for a four week period. Participants...

Leveraging information technology to address the health workforce gap

Post Date: 
2013-11-01
Publication: 
Bulletin of the World Health Organization
According to some estimates, the world needs more than 4 million additional physicians, nurses, pharmacists, laboratory technicians, midwives, community health workers (CHWs) and other front-line health workers. However, there is also a shortage of faculty that can provide high-quality training and...

HIV/AIDS education in traditional Indian systems of medicine: faculty perspectives

Post Date: 
2013-10-24
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Countries: 
Publication: 
Journal of Traditional Medicine and and Clinical Naturopathy
In India, HIV-infected individuals face numerous challenges in their search for treatments. Currently, western allopathic medicine (hereinafter ‘biomedicine’) offers antiretroviral therapy (ART) for HIV/AIDS and associated co-morbidities that have prolonged survival and improved quality of life...

India’s new policy to protect research participants

Post Date: 
2013-07-31
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Countries: 
Publication: 
The BMJ
Editorial Introduction: India, the country with the largest disease burden in the world,1 is now a major international hub for clinical research. However, a recent policy that was meant to mitigate important ethical concerns may have profound and unintended consequences for public health and may...

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