Presentations

Gupta A. Accessing MDR-TB Exposed Households: the PHOENiX MDR-TB Feasibility Study. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico.

Meet the Expert: Managing Tuberculosis in Pregnant Women and Newborns

Post Date:

2017-10-13

Gupta A. Meet the Expert: Managing Tuberculosis in Pregnant Women and Newborns. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico.

High Burden of Genital TB Among Women with Infertility in India - Need for an Intensified Approach

Post Date:

2017-10-13

Clinical Sites:

Naik SN , Chandanwale A, Joshi S, Mave V, Dhumal G, DeLuca A, Gupta A, Bollinger R. High Burden of Genital TB Among Women with Infertility in India - Need for an Intensified Approach. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico. October 13, 2017.

Biological Differences in Tuberculosis Diagnosis and Disease in Women

Post Date:

2017-10-12

Clinical Sites:

Mathad J. Biological Differences in Tuberculosis Diagnosis and Disease in Women. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico.

Symposium: From Bench to Bassinet: Scientific Innovations: The Fight against Maternal-Infant TB

Post Date:

2017-10-12

Clinical Sites:

Gupta A. Symposium: From Bench to Bassinet: Scientific Innovations: The Fight against Maternal-Infant TB. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico.

Barriers to Contact Screening and Isoniazid Preventive Therapy among Pediatric Contacts of Adults with Smear-positive Tuberculosis

Post Date:

2017-10-12

Clinical Sites:

Belgaumkar V , Chandanwale A, Valvi C, Khadse S, Jain D, Dhumal G, Bollinger RC, Deluca A. Barriers to Contact Screening and Isoniazid Preventive Therapy among Pediatric Contacts of Adults with Smear-positive Tuberculosis. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico.

Drug Susceptibility of Rifampin-resistant Tuberculosis using Whole Genome Sequencing to Identify Genes of Interest in Pune, India

Post Date:

2017-10-12

Clinical Sites:

Hinduja Hospital

Tornheim JA , Madugundu AK, Pradhan N, Bharadwaj R, Mave V, Golub J, Pandey A, Gupta A. Drug Susceptibility of Rifampin-resistant Tuberculosis using Whole Genome Sequencing to Identify Genes of Interest in Pune, India. 48th Annual Union World Conference of Lung Health. Guadalajara, Mexico.

Delays and Barriers to Early Treatment Initiation in Childhood Tuberculosis in India

Post Date:

2017-10-11

Countries:

Valvi C, Chandanwale A, Khadse S, Kulkarni R, Kadam D, Dhumal G , Deluca A, Bollinger RC. Delays and Barriers to Early Treatment Initiation in Childhood Tuberculosis in India. The 48th Union World Conference on Lung Health. Guadalajara, Mexico.

Lack of TB Knowledge among TST positive Household Contacts of Pulmonary Cases: A Missed Opportunity

Post Date:

2017-10-11

Countries:

DeLuca, A., Dhumal, G., Paradkar, P., Suryavanshi, N., Mave, V., Kohli, K., Shivakumar, S., Gupta. A. Lack of TB Knowledge among TST positive Household Contacts of Pulmonary Cases: A Missed Opportunity. The 48th Union World Conference on Lung Health. Guadalajara, Mexico.

Linezolid Experience among MDRTB Patients in Mumbai

Post Date:

2017-09-13

Countries:

Clinical Sites:

Hinduja Hospital

Tornheim J, Ganatra S, Deluca A, Banka R, Rodrigues C, Gupta A, Udwadia Z. Poster Presentation. Linezolid Experience among MDRTB Patients in Mumbai. ERS International Congress. European Respiratory Society. Milan, Italy.

Trends in Glycated Hemoglobin Levels and Implications for Diabetes Screening among Pulmonary Tuberculosis Cases Undergoing Treatment in India

Post Date:

2017-09-13

Countries:

Clinical Sites:

DY Patil

Gupte AN , Mave V, Meshram S, Lokhande R, Kadam D, Dharmshale S, Bharadwaj R, Kagal A, Pradhan N, Deshmukh S, Atre S, Sahasrabudhe T, Barthwal M, Meshram S, Kakrani A, Kulkarni V, Raskar S, Suryavanshi S, Shivakoti R, Chon S, Selvin E, Gupte N, Gupta A, Golub JE. Trends in Glycated Hemoglobin...

High Burden of Diabetes and Prediabetes among Adult Household Contacts of India

Post Date:

2017-09-13

Countries:

Clinical Sites:

NIRT

Shivakumar SVBY , Chandrasekaran P, Kumar AJMV, Paradkar M, Dhanasekaran K, Suryavanshi N, Thomas B, Kohli R, Thiruvengadam K, Kulkarni V, Hannah LE, Sivaramakrishnan GN, Pradhan N, Dolla C, Gupte A, Ramachandran G, DeLuca A, Meshram S, Bhardawaj R, Bollinger RC, Golub J, Selvaraj K, Gupte N,...

Gene Expression Profiles of Pediatric Tuberculosis Patients and Exposed Controls from India

Post Date:

2017-09-13

Countries:

Clinical Sites:

Hinduja Hospital

Tornheim JA , Paradkar M, Madugundu A, Gupte N, Kulkarni V, Sreenivasamurthy S, Raja R, Pradhan N, Shivakumar SVBY, Valvi C, Kohli R, Chandrasekaran P, Mave V, Pandey A, Gupta A. Gene Expression Profiles of Pediatric Tuberculosis Patients and Exposed Controls from India. RePORT International...

Hepatotoxicity in HIV+ Postpartum Women Initiating Efavirenz-Containing Regimens

Post Date:

2017-07-26

Countries:

Bhattacharya D , Gupta A, Tierney C, Huang S, Peters M, Chipato T, Martinson F, Dula D, George K, Chaktoura N, Klingman K, Gnanashanmugam D, Currier J, Fowler MG. Hepatotoxicity in HIV+ Postpartum Women Initiating Efavirenz-Containing Regimens. IAS 2017. International AIDS Society. Paris, France...

Hepatotoxicity in HIV+ Postpartum Women Initiating Efavirenz-Containing Regimens in PROMISE P1077

Post Date:

2017-05-31

Amita Gupta. Hepatotoxicity in HIV+ Postpartum Women Initiating Efavirenz-Containing Regimens in PROMISE P1077. 2017 IMPAACT Annual Meeting. Washington, DC. 2017

A5300B/IMPAACT 2003B – PHOENix MDR TB: Protecting Households on Exposure to Newly Diagnosed Index Multidrug-Resistant TB Patients

Post Date:

2017-05-30

Gupta, A. A5300B/IMPAACT 2003B – PHOENix MDR TB: Protecting Households on Exposure to Newly Diagnosed Index Multidrug-Resistant TB Patients. 2017 IMPAACT Annual Meeting. Washington, DC.

A5300/I2003/PHOENIx Trial Update

Post Date:

2017-05-30

Gupta, A. A5300/I2003/PHOENIx Trial Update. 2017 IMPAACT Annual Meeting. Washington, DC. 2017.

IMPAACT 2001: Trial of the Pharmacokinetics, Tolerability, and Safety of Once-Weekly Rifapentine and Isoniazid in HIV-infected and HIV-1-uninfected Pregnant and Postpartum Women with Latent Tuberculosis Infection

Post Date:

2017-05-30

Jyoti Mathad. IMPAACT 2001: Trial of the Pharmacokinetics, Tolerability, and Safety of Once-Weekly Rifapentine and Isoniazid in HIV-infected and HIV-1-uninfected Pregnant and Postpartum Women with Latent Tuberculosis Infection. 2017 IMPAACT Annual Meeting. Washington, DC. 2017.

CTRIUMPh Pediatric Biomarker Substudy

Post Date:

2017-05-30

Countries:

Clinical Sites:

NIRT

Tornheim J . Paradkar M. CTRIUMPh Pediatric Biomarker Substudy. 2017 IMPAACT Annual Meeting. Washington, DC. 2017.

Pages

Community-based health

Disease diagnosis

Drug resistance

Healthcare access and retention

MDR-TB

mHealth

Patient treatment adherence

Tuberculosis

Chronic disease

Diabetes

Nutrition

HIV

Maternal and child health

Environmental pollutants

Pediatrics

Inflammation

Antiretroviral therapy

Fever

Healthcare worker safety

Medical training

Pregnancy

Research training

Microbiome

Other

Social and behavioral research

Education: Distance

Education: Online

Breastfeeding

Cancer

Genomics

Sexually transmitted infections (non-HIV)

Mental health

Depression

Metabolomics

Stigma

Transcriptomics

A qualitative study of barriers to enrollment into free HIV care: perspectives of never-in-care HIV-positive patients and providers in Rakai, Uganda

Post Date:

2013-07-23

Countries:

Publication:

BioMed Research International

Background: Early entry into HIV care is low in Sub-Saharan Africa. In Rakai, about a third (31.5%) of HIV-positive clients who knew their serostatus did not enroll into free care services. This qualitative study explored barriers to entry into care from HIV-positive clients who had never...

Patterns of TB drug-resistance in a tertiary care facility in Pune, India

Post Date:

2013-07-18

Countries:

Publication:

Clinical Microbiology

Introduction:Globally, the emergence of multi-drug resistant tuberculosis (MDRTB) (defined as resistance to isoniazid (INH) and rifampicin (RIF) and extensively drug resistant (XDR-TB) (defined as resistance to INH, RIF, any fluoroquinolone and to at least one of the three injectable second...

Cost analyses of peer health worker and mHealth support interventions for improving AIDS care in Rakai, Uganda

Post Date:

2012-09-12

Countries:

Publication:

AIDS Care

A cost analysis study calculates resources needed to deliver an intervention and can provide useful information on affordability for service providers and policy-makers. We conducted cost analyses of both a peer health worker (PHW) and a mHealth (mobile phone) support intervention. Excluding...

H_pe for mHealth: More "y" or "o" on the horizon?

Post Date:

2013-04-13

Publication:

International Journal of Medical Informatics

Objective: Efforts in the domain of mobile health, or mHealth, have been criticized for the unfettered proliferation of pilots and a lack of a rigorous evidence base to support these strategies. In this letter, we present the response of a group of researchers in the mHealth community to the...

Screening for pulmonary tuberculosis in HIV-infected individuals: AIDS Clinical Trials Group Protocol A5253

Post Date:

2013-04-15

Countries:

Clinical Sites:

Publication:

International Journal of Tuberculosis and Lung Disease

Background: Improved tuberculosis (TB) screening is urgently needed for human immunodeficiency virus (HIV) infected patients. Methods: An observational, multi-country, cross-sectional study of HIV-infected patients to compare a standardized diagnostic...

Changes in HIV-1 subtypes B and C genital tract RNA in women and men after initiation of antiretroviral therapy

Post Date:

2013-03-26

Clinical Sites:

Publication:

Clinical Infectious Diseases

Background: Combination antiretroviral therapy (cART) reduces genital tract human immunodeficiency virus type 1 (HIV-1) load and reduces the risk of sexual transmission, but little is known about the efficacy of cART for decreasing genital tract viral load (GTVL) and differences in sex or HIV...

Correlates of lower comprehension of informed consent among participants enrolled in a cohort study in Pune, India

Post Date:

2013-03-15

Countries:

Publication:

International Health

Background: Optimum comprehension of informed consent by research participants is essential yet challenging. This study explored correlates of lower comprehension of informed consent among 1334 participants of a cohort study aimed at estimating HIV incidence in Pune, India. ...

Combination implementation for HIV prevention: moving from evidence to population-level impact

Post Date:

2013-01-15

Publication:

The Lancet Infectious Disease

The promise of combination HIV prevention-the application of multiple HIV prevention interventions to maximise population-level effects-has never been greater. However, to succeed in achieving significant reductions in HIV incidence, an additional concept needs to be considered: combination...

Household-based HIV counseling and testing as a platform for referral to HIV care and medical male circumcision in Uganda: a pilot evaluation

Post Date:

2012-12-13

Countries:

Publication:

PLOS One

Background: Combination HIV prevention initiatives incorporate evidence-based, biomedical and behavioral interventions appropriate and acceptable to specific populations, aiming to significantly reduce population-level HIV incidence. Knowledge of HIV serostatus is key to linkages to HIV care...

Tuberculosis in pregnant and postpartum women: Epidemiology, management, and research gaps

Post Date:

2012-12-15

Publication:

Clinical Infectious Diseases

Tuberculosis is most common during a woman's reproductive years and is a major cause of maternal-child mortality. National guidelines for screening and management vary widely owing to insufficient data. In this article, we review the available data on (1) the global burden of tuberculosis in...

Growth patterns among HIV-exposed infants receiving nevirapine prophylaxis in Pune, India

Post Date:

2012-10-31

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Clinical Sites:

Publication:

BMC Infectious Diseases

Background: India has among the highest rates of infant malnutrition. Few studies investigating the growth patterns of HIV-exposed infants in India or the impact of timing of HIV infection on growth in settings such as India exist. Methods: We used data from...

HIV transmitted drug resistance in adult and pediatric populations in Panama

Post Date:

2011-12-15

Countries:

Panama

Publication:

Revista Panamerica de Salud Publica--Pan American Journal of Public Health

Objective: To investigate the prevalence of transmitted drug-resistant HIV among adults in Panama by using a modified World Health Organization Threshold Survey (WHO-TS) and to investigate rates of initial resistance among HIV-positive infants in Panama. Methods: At...

Nutrition and disease progression pre-highly active antiretroviral therapy (HAART) and post-HAART: Can good nutrition delay time to HAART and affect response to HAART

Post Date:

2011-12-15

Publication:

American Journal of Clinical Nutrition

Several studies have investigated a variety of nutritional supplementation interventions in adults with HIV. In this narrative review, we summarize the evidence from 31 clinical trials that explore clinical benefits of macronutrient and micronutrient supplementation in this population while...

Pooled individual data analysis of five randomized trials of infant nevirapine prophylaxis to prevent breast-milk HIV-1 transmission

Post Date:

2012-10-19

Countries:

Clinical Sites:

Publication:

Clinical Infectious Diseases

Background: In resource-limited settings, mothers infected with human immunodeficiency virus type 1 (HIV-1) face a difficult choice: breastfeed their infants but risk transmitting HIV-1 or not breastfeed their infants and risk the infants dying of other infectious diseases or...

Early mortality in adults initiating antiretroviral therapy (ART) in low- and middle-income countries (LMIC): a systematic review and meta-analysis

Post Date:

2011-12-15

Publication:

PLOS One

Background: We systematically reviewed observational studies of early mortality post-antiretroviral therapy (ART) initiation in low- and middle-income countries (LMIC) in Asia, Africa, and Central and South America, as defined by the World Bank, to summarize what is known. ...

Impact of maternal human immunodeficiency virus infection on pregnancy and birth outcomes in Pune, India

Post Date:

2011-12-15

Countries:

Clinical Sites:

Publication:

AIDS Care

Little is known about birth outcomes for HIV-infected women in India. We examine maternal and neonatal birth outcomes in HIV-infected women within the context of enhanced pre-natal care associated with a randomized clinical trial conducted in Pune, India. Birth outcomes of 212 HIV-infected...

Impact of a mHealth intervention for peer health workers on AIDS Care in rural Uganda: a mixed methods evaluation of a cluster-randomized trial

Post Date:

2011-11-15

Countries:

Publication:

AIDS and Behavior

Mobile phone access in low and middle-income countries is rapidly expanding and offers an opportunity to leverage limited human resources for health. We conducted a mixed methods evaluation of a cluster-randomized trial exploratory substudy on the impact of a mHealth (mobile phone) support...

Symptom screening among HIV-infected pregnant women is acceptable and has high negative predictive value for active tuberculosis

Post Date:

2011-11-15

Countries:

Clinical Sites:

Publication:

Clinical Infectious Diseases

Symptom screening is a recommended component of intensified case-finding (ICF) for pulmonary tuberculosis (TB) among HIV-infected individuals. Symptomatic individuals are further investigated to either exclude or diagnose pulmonary TB, thus reducing the number of individuals requiring costly...

Faculty diversity programs in U.S. medical schools and characteristics associated with higher faculty diversity.

Post Date:

2011-10-15

Countries:

United States

Publication:

Academic Medicine

Purpose: To describe diversity programs for racial and ethnic minority faculty in U.S. medical schools and identify characteristics associated with higher faculty diversity. Method: The authors conducted a cross-sectional survey study of leaders of diversity programs at 106 U.S. MD-granting medical...

Evaluation of a multimodal, distance learning HIV management course for clinical care providers in India

Post Date:

2012-10-01

Countries: