Publications

Baseline duty hours recorded with time-cards: a pre-regulation study of internal medicine residents

Post Date: 
2006-07-15
Publication: 
Medical Education
Country: 
Objective: The acquisition of data on resident duty hours has been largely dependent on self-report surveys collected in the surgical literature. We sought to implement and describe a simple method for monitoring internal medicine resident duty hours by using time-cards. Design: In 2002, internal...

Evaluation of serologic screening for identification of chronic Salmonella typhi carriers in Vietnam

Post Date: 
2006-07-10
Publication: 
International Journal of Infectious Diseases
Objectives: To determine the utility of screening anti-Vi antibodies to detect chronic Salmonella Typhi carriers in an endemic community. Methods: We conducted a community-based serologic survey for anti-Vi antibodies to identify chronic Salmonella Typhi carriers in a typhoid endemic region in...

High rates of syphilis among STI patients are contributing to the spread of HIV-1 in India

Post Date: 
2006-04-15
Publication: 
Sexually Transmitted Infections
Country: 
Background: Recent syphilis outbreaks have raised concern regarding the potential enhancement of HIV transmission. The incidence of syphilis and its association with HIV‐1 infection rates among a cohort of sexually transmitted infection (STI) clinic attendees was investigated. Methods: 2732 HIV‐1...

Low HIV-1 incidence among married serodiscordant couples in Pune, India

Post Date: 
2006-03-15
Publication: 
Journal of Acquired Immune Deficiency Syndromes
Country: 
Unlike commercial sex workers and patients attending sexually transmitted infection (STI) clinics, married couples are not typically targeted for HIV risk reduction programs in India. Thus, married partners of HIV-infected persons are at particularly high risk for HIV infection. Between September...

The expanding realm of heterologous immunity: friend or foe?

Post Date: 
2006-02-15
Publication: 
Cellular Microbiology
Antecedent or current infections can alter the immunopathologic outcome of a subsequent unrelated infection. Immunomodulation by co-infecting pathogens has been referred to as 'heterologous immunity' and has been postulated to play a role in host susceptibility to disease, tolerance to organ...

Screening for HIV dementia in an HIV, clade C-infected population in India

Post Date: 
2006-02-12
Publication: 
Journal of Neurovirology
Country: 
Although human immunodeficiency virus (HIV) clade C virus infects the largest populations worldwide, to date there are no prospective studies reported thus far to determine the incidence or prevalence of HIV dementia in this population. HIV clade C virus is a CCR5-tropic virus and thus...

Rate of hospitalization and inpatient care costs for HIV-1 infected in Pune, India

Post Date: 
2006-02-01
Publication: 
National Medical Journal of India
Country: 
Background: The transition of human immunodeficiency virus (HIV) infection to acquired immune deficiency syndrome (AIDS) has begun in India, and an increase in AIDS-related hospitalizations and deaths is an anticipated challenge. We estimated the rates of hospitalization and inpatient care costs...

High HIV prevalence among a high-risk subgroup of women attending sexually transmitted infection clinics in Pune, India

Post Date: 
2006-01-01
Publication: 
Journal of Acquired Immune Deficiency Syndromes
Country: 
Objectives: To investigate changes over a decade in prevalence and correlates of HIV among high-risk women attending sexually transmitted infection (STI) clinics in Pune, India, who deny a history of commercial sex work (CSW). Methods: From 1993 to 2002, 2376 women attending 3 STI clinics in Pune...

Correlates and trend of HIV prevalence among female sex workers attending sexually transmitted disease clinics in Pune, India (1993-2002)

Post Date: 
2006-01-01
Publication: 
Journal of Acquired Immune Deficiency Syndromes
Country: 
In India, substantial efforts have been made to increase awareness about HIV/AIDS among female sex workers (FSWs). We assessed the impact of awareness regarding safe sex in a cohort of FSWs by studying trends in HIV prevalence, sexually transmitted diseases (STDs), and risk behaviors measured from...

Mycobacterial-induced potentiation of type 1 immune responses and protection against malaria is host-specific

Post Date: 
2005-12-15
Publication: 
Infection and Immunity
Malaria and tuberculosis are endemic in many regions of the world, and coinfection with the two pathogens is common. In this study, we examined the effects of long- and short-term infection with Mycobacterium tuberculosis on the course of a lethal form of murine malaria in resistant (C57BL/6) and...

Stop AIDS-keep the promise

Post Date: 
2005-12-15
Publication: 
Indian Journal of Medical Research
Summary not available online

Adult botulism type F in the United States, 1981-2002

Post Date: 
2005-12-13
Publication: 
Neurology
Background: Clostridium botulinum neurotoxin types A, B, and E cause most cases of the paralytic disease botulism. Little is known about the epidemiology, clinical features, or microbiology of botulism type F. Methods: Cases of adult type F botulism were identified by review of data collected by...

Feasibility of voluntary counseling and testing services for HIV among pregnant women presenting in labor in Pune, India

Post Date: 
2005-08-01
Publication: 
international Journal of STD & AIDS
Country: 
Factors affecting the eligibility and acceptability of voluntary counselling and rapid HIV testing (VCT) were examined among pregnant womenpresenting in labour in Pune, India. Of the 6702 total women appearing at the delivery room from April 2001 to March 2002, 4638 (69%) were admitted for normal...

Antifungal interventions for the primary prevention of cryptococcal disease in adults with HIV

Post Date: 
2005-07-20
Publication: 
Cochrane Database of Systematic Reviews
Infection with the human immunodeficiency virus (HIV) leads to progressive destruction and weakening of the body's immune system. Patients with advanced HIV disease are vulnerable to various diseases, called opportunistic infections (OIs), which most people with normal immune systems are protected...

Genetic diversification and recombination of HIV type 1 group M in Kinshasa, Democratic Republic of Congo

Post Date: 
2005-07-15
Publication: 
AIDS Research and Human Retroviruses
As the HIV-1 pandemic becomes increasingly complex, the genetic characterization of HIV strains bears important implications for vaccine research. To better understand the molecular evolution of HIV-1 viral diversity, we performed a comparative molecular analysis of HIV strains collected from high-...

Necrotizing enterocolitis associated with Clostridium perfringens type A in previously healthy North-American adults

Post Date: 
2005-07-15
Publication: 
Journal of the American College of Surgeons
Background: Necrotizing enteritis associated with Clostridium perfringens type C ("pigbel") is a well-known syndrome in severely protein-deprived populations in the Pacific. It is exceedingly rare in the developed world. C perfringens type A is a common cause of acute gastroenteritis and, in a...

Antimicrobial-resistant Shigella sonnei: Limited antimicrobial treatment options for children and challenges of interpreting in vitro azithromycin susceptibility

Post Date: 
2005-06-15
Publication: 
Journal of Pediatric Infectious Diseases
Background: Antimicrobial-resistant Shigella sonnei is a growing problem in the United States and poses treatment challenges particularly among children. Azithromycin is recommended as an alternative oral agent for shigellosis. Methods: All isolates of Shigella submitted to Johns Hopkins clinical...

IJMR Special Issue on HIV/AIDS: Editorial overview

Post Date: 
2005-04-15
Publication: 
Indian Journal of Medical Research
Country: 
No summary available online

High-risk behaviour in young men attending sexually transmitted disease clinics in Pune, India.

Post Date: 
2005-04-15
Publication: 
AIDS Care
Country: 
The present study reports sexual risk factors associated with HIV infection among men attending two sexually transmitted disease (STD) clinicsin Pune, India and compares these behaviours between young and older men. Between April 1998 and May 2000, 1872 STD patients were screened for HIV infection...

Making the choice: the translation of global HIV and infant feeding policy to local practice among mothers in Pune, India

Post Date: 
2005-04-15
Publication: 
The Journal of Nutrition
Country: 
In 2003, India had over 5.1 million infected individuals living with HIV/AIDS. The percentage of all HIV cases attributed to perinatal transmission has been increasing steadily from 0.33% of total cases in 1999 to 2.80% in 2004. Recent statistics indicate that over 130,000 infants have been...

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