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¡Vive!: Designing an intervention to improve timely HIV diagnosis among Latino immigrant men

Post Date:

2018-01-23

Countries:

Publication:

Progress in Community Health Partnerships

Background: Latinos, particularly immigrant men, are more likely to present late to care for human immunodeficiency virus (HIV) infection. Objectives: This manuscript describes the development of ¡Sólo Se Vive Una Vez! (¡Vive!) (You Only Live Once), a multilevel (individual and community)...

Gender-based violence screening methods preferred by women visiting a public hospital in Pune, India

Post Date:

2018-01-22

Countries:

India

Clinical Sites:

BJGMC

Publication:

BMC Womens Health

BMC Womens Health : In our study, 23% of women reported experiencing gender based violence, and 90% reported they had never been asked about it in the healthcare setting.

Secondhand smoke exposure and validity of self-report in low-income women and children in India

Post Date:

2018-01-10

Countries:

India

Publication:

Pediatrics

Pediatrics: Dr. Jessica Elf and colleagues evaluated the validity of standard self-reported measures for secondhand smoke (SHS) exposure among women and children in urban India.

What will it take to reduce HIV incidence in the United States: A mathematical modeling analysis

Post Date:

2018-01-06

Countries:

United States

Publication:

Open Forum Infectious Diseases

Modeling and simulations suggest that cutting HIV incidence in half by 2025 will require 95% of people living with HIV to be engaged in care.

Suboptimal antituberculosis drug concentrations and outcomes in small and HIV‐coinfected children in India: Recommendations for dose modifications

Post Date:

2017-12-16

Countries:

India

Publication:

Clinical Pharmacology and Therapeutics

This work aimed to evaluate the once-daily antituberculosis treatment as recommended by the new Indian pediatric guidelines. Isoniazid, rifampin, and pyrazinamide concentration-time profiles and treatment outcome were obtained from 161 Indian children with drug-sensitive tuberculosis undergoing...

Isoniazid concentrations in hair and plasma area-under-the-curve exposure among children with tuberculosis

Post Date:

2017-12-07

Countries:

India

Clinical Sites:

BJGMC

NIRT

Publication:

PLOS One

PLOS One: Mave and colleagues compared TB drug exposure in plasma and hair samples among a small cohort of children.

The use of clinical decision support in reducing diagnosis of and treatment of asymptomatic bacteriuria

Post Date:

2017-12-06

Countries:

United States

Publication:

Journal of Hospital Medicine

Clinical decision support embedded within the electronic health record is a potential antibiotic stewardship strategy for hospitalized patients.

Antibiotic utilization and the role of suspected and diagnosed mosquito borne illness among adults and children with acute febrile illness in Pune, India

Post Date:

2017-12-04

Countries:

India

Clinical Sites:

BJGMC

Publication:

Clinical Infectious Diseases

Mosquito-borne disease identification is associated with reduced empiric antibiotic use and faster antibiotic discontinuation.

Suboptimal anti-tuberculosis drug concentrations and outcomes in small and HIV coinfected children in India: recommendations for dose modifications

Post Date:

2017-12-01

Countries:

India

Clinical Sites:

NIRT

Publication:

Clinical Pharmacology and Therapeutics

This work aimed to evaluate the once-daily anti-tuberculosis treatment as recommended by the new Indian pediatric guidelines. Isoniazid, rifampin and pyrazinamide concentration-time profiles and treatment outcome were obtained from 161 Indian children with drug-sensitive tuberculosis undergoing...

Prevalence of dysglycemia and clinical presentation of pulmonary tuberculosis in Western India

Post Date:

2017-12-01

Countries:

India

Clinical Sites:

BJGMC

Publication:

International Journal of Tuberculosis and Lung Disease

Objectives: To estimate the prevalence and risk factors of pre-diabetes mellitus (DM) and DM, and its associations with the clinical presentation of tuberculosis (TB). Design: Screening for DM was conducted among adults (age  18 years) with confirmed TB between December 2013 and January 2017. We...

HIV prevention efforts and incidence in HIV in Uganda

Post Date:

2017-11-30

Countries:

Uganda

Publication:

New England Journal of Medicine

In a large study in Uganda, Dr. Larry Chang and colleagues found that combination HIV prevention has population level implications, reducing new infections by 42%.

People with tuberculosis falling through the cracks

Post Date:

2017-11-01

Countries:

India

Publication:

National Medical Journal of India

India accounts for approximately one-quarter of the estimated global burden of TB and MDR-TB. [4] Achieving the 2015 WHO End TB Strategy[5] and the latest Government of India target of TB elimination by 2025[6] will require substantial efforts and funding to continue to improve TB care in India...

Impact of a community health worker HIV treatment and prevention intervention in an HIV hotspot fishing community in Rakai, Uganda (mLAKE): study protocol for a randomized controlled trial

Post Date:

2017-10-23

Countries:

Uganda

Publication:

Trials

Abstract Background: Effective yet practical strategies are needed to increase engagement in HIV treatment and prevention services, particularly in high-HIV-prevalence hotspots. We designed a community-based intervention called "Health Scouts" to promote uptake and adherence to HIV services in a...

Risk factors for early mortality on antiretroviral therapy in advanced HIV-infected adults

Post Date:

2017-10-23

Countries:

India

Clinical Sites:

BJGMC

Publication:

AIDS

Background: Many HIV-infected individuals present with advanced HIV disease. These patients are at high risk of death after antiretroviral therapy (ART) initiation, but risk factors for death in these patients are unclear. Methods: We used data from a multisite randomized trial comparing empiric vs...

Of testing and treatment: Implications of implementing new regimens for multidrug-resistant tuberculosis

Post Date:

2017-10-01

Publication:

Clinical Infectious Diseases

A novel, shorter-course regimen for treating multidrug-resistant (MDR) tuberculosis was recently recommended by the World Health Organization. However, the most appropriate use of drug susceptibility testing (DST) to support this regimen is less clear. Implementing countries must therefore often...

Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: a systematic analysis for the Global Burden of Disease Study 2016

Post Date:

2017-09-16

Publication:

The Lancet

Abstract Background: Detailed assessments of mortality patterns, particularly age-specific mortality, represent a crucial input that enables health systems to target interventions to specific populations. Understanding how all-cause mortality has changed with respect to development status can...

Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016

Post Date:

2017-09-16

Publication:

The Lancet

Abstract Background: As mortality rates decline, life expectancy increases, and populations age, non-fatal outcomes of diseases and injuries are becoming a larger component of the global burden of disease. The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a...

Measuring progress and projecting attainment on the basis of past trends of the health-related Sustainable Development Goals in 188 countries: an analysis from the Global Burden of Disease Study 2016

Post Date:

2017-09-12

Publication:

The Lancet

Abstract Background: The UN's Sustainable Development Goals (SDGs) are grounded in the global ambition of "leaving no one behind". Understanding today's gains and gaps for the health-related SDGs is essential for decision makers as they aim to improve the health of populations. As part of the...

Challenges in the evaluation of interventions to improve engagement along the HIV care continuum in the United States: a systematic review

Post Date:

2017-07-17

Countries:

United States

Publication:

AIDS and Behavior

Dr. Maunank Shah & colleagues review interventions to keep HIV patients linked to care.

Healthcare Access and Quality Index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the Global Burden of Disease Study 2015

Post Date:

2017-07-15

Publication:

The Lancet

Abstract Background: National levels of personal health-care access and quality can be approximated by measuring mortality rates from causes that should not be fatal in the presence of effective medical care (ie, amenable mortality). Previous analyses of mortality amenable to health care only...