Publications - United States

What Will It Take to End HIV in the United States? : A Comprehensive, Local-Level Modeling Study

Post Date:

2021-09-24

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Annals of Internal Medicine

Background: The Ending the HIV Epidemic (EHE) initiative aims to reduce incident HIV infections by 90% over a span of 10 years. The intensity of interventions needed to achieve this for local epidemics is unclear. Objective: To estimate the effect of HIV interventions at the city level. Design: A...

Sex and gender differences in COVID testing, hospital admission, presentation, and drivers of severe outcomes in the DC/Maryland region

Post Date:

2021-08-31

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medRxiv

Rates of severe illness and mortality from SARS-CoV-2 are greater for males, but the mechanisms for this difference are unclear.

Comparison of Time to Clinical Improvement With vs Without Remdesivir Treatment in Hospitalized Patients With COVID-19

Post Date:

2021-03-24

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JAMA Network Open

Just Published in JAMA Network Open: In this retrospective analysis, remdesivir was associated with faster clinical improvement of COVID-19 in a cohort of predominantly non-White patients

Aspergillosis Complicating Severe Coronavirus Disease

Post Date:

2021-01-01

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EID Journal

Aspergillosis complicating severe influenza infection has been increasingly detected worldwide. Recently, coronavirus disease–associated pulmonary aspergillosis (CAPA) has been detected through rapid reports, primarily from centers in Europe. We provide a case series of CAPA, adding 20 cases to the...

Tocilizumab for the Treatment of COVID-19 Among Hospitalized Patients: A Matched Retrospective Cohort Analysis

Post Date:

2020-12-28

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Open Forum Infectious Diseases

Background: There is currently no single treatment that mitigates all harms caused by severe acute respiratory syndrome coronavirus 2 infection. Tocilizumab, an interleukin-6 antagonist, may have a role as an adjunctive immune-modulating therapy. Methods: This was an observational retrospective...

Nevirapine pharmacokinetics in HIV-infected persons receiving rifapentine and isoniazid for TB prevention

Post Date:

2020-11-26

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The Journal of Antimicrobial Chemotherapy

Background: The use of rifamycin antibiotics for TB prevention carries a risk of detrimental drug-drug interactions with concomitantly used ART. Objectives: To evaluate the interaction of the antiretroviral drug nevirapine in combination with 4 weeks of daily rifapentine and isoniazid for TB...

Patient Trajectories Among Persons Hospitalized for COVID-19: A Cohort Study

Post Date:

2020-09-22

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Annals of Internals Medicine

Risk factors for progression of coronavirus 2019 (COVID-19) to severe disease or death are underexplored in U.S. cohorts.

Pharmacokinetics and drug-drug interactions of isoniazid and efavirenz in pregnant women living with HIV in high TB incidence settings: importance of genotyping

Post Date:

2020-09-09

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Clinical Pharmacology and Therapeutics

World Health Organization guidelines recommend that individuals living with HIV receive ≥6 months of isoniazid preventive therapy, including pregnant women.

Effects of Pregnancy and Isoniazid Preventive Therapy on M. tuberculosis Interferon Gamma Response Assays in Women with HIV

Post Date:

2020-07-28

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Clinical Infectious Diseases

944 women with HIV participating in a randomized, double-blind, placebo-controlled study comparing 28 weeks of IPT antepartum versus postpartum, were tested by QuantiFERON-gold-in-tube (QGIT) antepartum and by QGIT and tuberculin skin test (TST) at delivery and postpartum.

SARS-CoV-2 Positivity Rate for Latinos in the Baltimore-Washington, DC Region

Post Date:

2020-06-18

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JAMA

This study characterizes the trends in rates of SARS-CoV-2 positive test results among individuals in the Baltimore-Washington, DC area by self-reported race/ethnicity.

Undocumented U.S. Immigrants and Covid-19

Post Date:

2020-03-27

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New England Journal of Medicine

NEJM: Kathleen Page and colleagues outline COVID-19 hardships faced by undocumented immigrants and strategies needed to ensure they have access to care.

Community-Driven Priorities in Smartphone Application Development: Leveraging Social Networks to Self-Manage Type 2 Diabetes in a Low-Income African American Neighborhood

Post Date:

2019-07-30

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International Journal of Environmental Research and Public Health

Social networks have the potential to enhance Type 2 Diabetes Mellitus (T2DM) self-management. We used qualitative methods to study if and how mobile application (app) functions that mobilize social resources to improve T2DM management would be desired in a low-income African American community. Data were collected through community discussions and in-depth interviews with 78 participants in 2016–2018.

Advancing Patient-Centered Care in Tuberculosis Management: A Mixed-Methods Appraisal of Video Directly Observed Therapy

Post Date:

2019-06-25

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Open Forum Infectious Diseases

OFID : Study compared directly-observed therapy with video-based observed therapy using the emocha mobile health platform

A population pharmacokinetic analysis shows that arylacetamide deacetylase (AADAC) gene polymorphism and HIV infection affect the exposure of rifapentine

Post Date:

2019-03-29

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Antimicrobial Agents Chemotherapy

New analysis published in Antimicrobial Agents and Chemotherapy!

Evaluation of an adapted Project Connect community based intervention among professionals serving young minority men

Post Date:

2019-03-15

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Sexually Transmitted Diseases

BACKGROUND: To address sexual and reproductive health (SRH) needs of young minority urban males, we developed and evaluated Project Connect Baltimore (Connect), which was adapted from a program with demonstrated effectiveness among young females. The objectives were to determine (1) the...

Impact of providing preexposure prophylaxis for human immunodeficiency virus at clinics for sexually transmitted infections in Baltimore City: An agent-based model

Post Date:

2018-12-15

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Sexually Transmitted Diseases

BACKGROUND: Preexposure prophylaxis (PrEP) greatly reduces the risk of human immunodeficiency virus (HIV) acquisition, but its optimal delivery strategy remains uncertain. Clinics for sexually transmitted infections (STIs) can provide an efficient venue for PrEP delivery. ...

Immigration legal services as a structural HIV intervention for Latinx sexual and gender minorities

Post Date:

2018-11-21

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Lack of legal immigration status is associated with poor HIV-related outcomes for immigrant Latinx sexual and gender minorities (LSGM). LSGM often meet eligibility criteria for legal immigration relief. A Medical-Legal Partnership (MLP) may thus be strategic to improve their health. We know...

The role of perceived friend depression and perceived stigma on self-reported depression among individuals who use drugs

Post Date:

2018-11-15

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Journal of Community Psychology

Depression and substance use are highly comorbid, and stigmatized, mental health conditions influenced by social network factors. The objective of this study was to explore the role of perceived depression and perceived mental health stigma among friends on self-reported depression over time...

Missed opportunities to address pregnancy prevention with young men in primary care

Post Date:

2018-11-15

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Clinical Pediatrics

Young men (aged 15-24 years) have pregnancy prevention needs, yet little is known about whether they perceive they learn about pregnancy prevention in primary care. A sample of 190 young men seen in primary care in one city from April 2014 to September 2016 were assessed on perceived learning...

Centro SOL: A community-academic partnership to care for undocumented immigrants in an emerging Latino area

Post Date:

2018-10-30

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Academic Medicine

PROBLEM: From 2000 to 2014, the Latino population in Baltimore city, an emerging Latino settlement area, has experienced rapid growth. Many of these individuals are undocumented and not eligible for coverage. Academic medical centers often lead the way in addressing the health needs of...

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