Publications by Year (2019)

Development and validation of HIV-ASSIST, an online, educational, clinical decision support tool to guide patient-centered ARV regimen selection

Post Date: 
2019-10-01
Publication: 
Journal of Acquired Immune Deficiency Syndromes
New in JAIDS: Maunank Shah and colleagues deveoped HIV-ASSIST, a patient-centric educational decision support tool that provides ARV recommendations for a diverse set of patient scenarios.

Use of smartphone-based video Directly Observed Therapy (vDOT) in tuberculosis care: Single-arm, prospective feasibility study

Post Date: 
2019-08-30
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Publication: 
Journal of Medical Internet Research
Video-based monitoring is increasingly used as an efficient and low cost alternative to in-person observation and monitoring of TB patients. It showed promise in the high TB setting of India, too.

Inclusion of key populations in clinical trials of new antituberculosis treatments: Current barriers and recommendations for pregnant and lactating women, children, and HIV-infected persons

Post Date: 
2019-08-15
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Publication: 
PLOS Medicine
PLOS Medicine: Dr. Amita Gupta and colleagues discuss the scientific and ethical basis for including pregnant and lactation women, children, and HIV+ patients in tuberculosis therapeutic clinical trials.

A tuberculosis-free world: is it a delusion?

Post Date: 
2019-08-12
Publication: 
The Lancet
The Lancet: Dr. Sachin Atre's correspondence questions progress and global commitment toward TB elimination.

Development and validation of HIV-ASSIST, an online, educational, clinical decision support tool to guide patient-centered ARV regimen selection

Post Date: 
2019-07-31
Publication: 
Journal of Acquired Immune Deficiency Syndromes
Maunank Shah and colleagues invented HIV-ASSIST, an online decision-making tool that helps clinicians determine what antiretroviral therapies will best meet the needs of individual HIV patients. This paper in JAIDS discusses what they found in testing the tool's validity.

Third-line antiretroviral therapy in low-income and middle-income countries (ACTG A5288): a prospective strategy study

Post Date: 
2019-07-29
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Publication: 
Lancet HIV
BACKGROUND: Antiretroviral therapy (ART) management is challenging for individuals in resource-limited settings presenting for third-line treatment because of complex resistance patterns, partly due to reduced access to viral load monitoring. We aimed to evaluate use of newer antiretroviral drugs...

The Right and Left Hands of the State — Two Patients at Risk of Deportation

Post Date: 
2019-07-18
Publication: 
New England Journal of Medicine
NEJM: Dr. Kathleen Page and colleagues offer guidance for clinicians on meeting the needs of patients in an era of punitive immigration policy

HIV-ASSIST

Post Date: 
2019-07-16
Publication: 
HIVSpecialist
HIVSpecialist: Dr. Maunank Shah and colleagues chronicle the development of HIV-ASSIST, a tool to help guide selections for patient-centered antiretroviral therapy.

Long-acting or extended-release antiretroviral products for HIV treatment and prevention in infants, children, adolescents, and pregnant and breastfeeding women: knowledge gaps and research priorities

Post Date: 
2019-07-15
Publication: 
Lancet HIV
Lancet HIV : This paper summarizes findings of the Long acting/Extended Release Antiretroviral Resource Program workshop, and offers recommendations for developing ARV products for HIV treatment and prevention in infants, children, adolescents, and pregnant and breastfeeding women

High risk for latent tuberculosis infection among medical residents and nursing students in India

Post Date: 
2019-07-08
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Publication: 
PLoS One
PLoS ONE: Self-reported TB exposure is underreported, and uptake of LTBI prevention therapy remains low

Advancing the development of new tuberculosis treatment regimens: The essential role of translational and clinical pharmacology and microbiology

Post Date: 
2019-07-05
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Publication: 
PLOS
Application of clinical pharmacology best practices is essential to the efficient and rational development of drugs. In general, knowledge gained about exposure–response relationships in preclinical models aids drug and dose selection in human studies, and biomarkers and pharmacokinetic (PK) data...

Mobile phone access and comfort: implications for HIV and tuberculosis care in India and South Africa.

Post Date: 
2019-07-01
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Publication: 
International Journal of Tuberculosis and Lung Disease
SETTING: India and South Africa shoulder the greatest burden of tuberculosis (TB) and human immunodeficiency virus (HIV) infection respectively, but care retention is suboptimal. OBJECTIVE: We conducted a study in Pune, India, and Matlosana, South Africa to identify the factors associated with...

Advancing Patient-Centered Care in Tuberculosis Management: A Mixed-Methods Appraisal of Video Directly Observed Therapy

Post Date: 
2019-06-25
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Publication: 
Open Forum Infectious Diseases
OFID : Study compared directly-observed therapy with video-based observed therapy using the emocha mobile health platform

Age-specific prevalence of TB infection among household contacts of pulmonary tuberculosis: Is it time for TB preventive therapy?

Post Date: 
2019-06-21
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Publication: 
Transactions of the Royal Society of Tropical Medicine and Hygiene
BACKGROUND: Household contacts (HHCs) of TB patients are at high risk of developing evidence of latent TB infection (LTBI) and active disease from the index patient. We estimated the age-specific prevalence of LTBI and the force of infection (FI), as a measure of recent transmission, among HHCs of...

Users beware! Biological variation in complete blood counts over short time intervals

Post Date: 
2019-05-29
Publication: 
BMJ Evidence Based Medicine
New publication in BMJ Evidence Based Medicine looks at CBC count variations in blood drawn over a short time period

Assessment of lung function in successfully treated tuberculosis reveals high burden of ventilatory defects and COPD

Post Date: 
2019-05-23
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Publication: 
PLoS One
New in PLoS One: We found a high burden of lung function defects and COPD in tuberculosis cases who successfully completed treatment, suggesting a need for lung function screening as part of patient management.

High prevalence of insulin resistance and occurrence prior to hyperinsulinemia threshold among people living with HIV in Pune, India

Post Date: 
2019-05-21
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Publication: 
Diabetes Metabolic Syndrome: Clinical Research & Reviews
BACKGROUND Diabetes prevalence in HIV is not well characterized for India, despite the high burden of both individual diseases. Epidemiology of insulin resistance (IR): a precursor to diabetes, and its associated risk factors are also poorly understood in Asian Indian people living with HIV (PLHIV...

Sub-therapeutic rifampicin concentration is associated with unfavourable tuberculosis treatment outcomes

Post Date: 
2019-05-10
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Publication: 
Clinical Infectious Diseases
Rifampicin concentrations were sub-therapeutic in most Indian patients taking a thrice-weekly TB regimen

Venezuela's Public Health Crisis: A Regional Emergency

Post Date: 
2019-04-11
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Publication: 
Lancet
The Lancet: The economic crisis in Venezuela has eroded the country's health-care infrastructure and threatened public health.

Venezuela’s Humanitarian Emergency

Post Date: 
2019-04-11
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Countries: 
Publication: 
Report from Human Rights Watch
In January 2019, hundreds of thousands of Venezuelans took to the streets, following an appeal by National Assembly president Juan Guaidó, who asked the Venezuelan people to mobilize in support of restoring constitutional order in the country.

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