Publications - Patient treatment adherence

Isoniazid concentrations in hair and plasma area-under-the-curve exposure among children with tuberculosis

Post Date: 
2017-12-07
Publication: 
PLOS One
Country: 
PLOS One: Mave and colleagues compared TB drug exposure in plasma and hair samples among a small cohort of children.

Challenges in the evaluation of interventions to improve engagement along the HIV care continuum in the United States: a systematic review

Post Date: 
2017-07-17
Publication: 
AIDS and Behavior
Country: 
Dr. Maunank Shah & colleagues review interventions to keep HIV patients linked to care.

Qualitative insights into implementation, processes, and outcomes of a randomized trial on peer support and HIV care engagement in Rakai, Uganda

Post Date: 
2017-01-10
Publication: 
BMC Infectious Diseases
Country: 
BACKGROUND: People living with human immunodeficiency virus (HIV) who have not yet initiated antiretroviral therapy (ART) can benefit from being engaged in care and utilizing preventive interventions. Community-based peer support may be an effective approach to promote these important HIV services...

Community-based interventions to improve and sustain antiretroviral therapy adherence, retention in HIV care and clinical outcomes in low- and middle-income countries for achieving the UNAIDS 90-90-90 targets

Post Date: 
2016-07-30
Publication: 
Current HIV/AIDS Reports
Country: 
Little is known about the effect of community versus health facility-based interventions to improve and sustain antiretroviral therapy (ART) adherence, virologic suppression, and retention in care among HIV-infected individuals in low- and middle-income countries (LMICs). We systematically searched...

Determinants of default from tuberculosis treatment among patients with drug-susceptible tuberculosis in Karachi, Pakistan: a mixed methods study

Post Date: 
2015-11-12
Publication: 
PLOS One
Country: 
Purpose: Non-adherence to tuberculosis therapy can lead to drug resistance, prolonged infectiousness, and death; therefore, understanding what causes treatment default is important. Pakistan has one of the highest burdens of tuberculosis in the world, yet there have been no qualitative studies in...

Effectiveness of peer support on care engagement and preventive care intervention utilization among pre-antiretroviral therapy, HIV-infected adults in Rakai, Uganda: a randomized trial

Post Date: 
2015-08-14
Publication: 
AIDS and Behavior
Country: 
442 pre-ART, HIV-infected adults were randomized to peer support consisting of structured home visits to promote clinic attendance and preventive care intervention use or standard of care. At baseline, 62 % reported previously visiting an HIV clinic, 45 % reported taking cotrimoxazole prophylaxis,...

Impact of patient-selected care buddies on adherence to HIV care, disease progression and conduct of daily life among pre-antiretroviral HIV-infected patients in Rakai, Uganda: a randomized controlled trial

Post Date: 
2015-06-01
Publication: 
Journal of Acquired Immune Deficiency Syndromes
Country: 
Background: Data are limited on effects of household or community support persons ("care buddies") on enrollment into and adherence to pre-antiretroviral HIV care. We assessed the impact of care buddies on adherence to HIV clinic appointments, HIV progression, and conduct of daily life among pre-...

Durable suppression of HIV-1 after virologic monitoring-based antiretroviral adherence counseling in Rakai, Uganda

Post Date: 
2015-05-26
Publication: 
PLOS One
Country: 
Objectives: HIV viral load is recommended for monitoring antiretroviral treatment and identifying treatment failure. We assessed the durability of viral suppression after viral load-triggered adherence counseling among patients with HIV viremia 6 months after ART initiation. Design: Observational...

Analysis of latent tuberculosis infection treatment adherence among refugees and other patient groups referred to the Baltimore City Health Department TB clinic

Post Date: 
2015-02-15
Publication: 
Journal of Immigrant and Minority Health
Country: 
We sought to determine the proportion of refugee patients at the Baltimore City Health Department Tuberculosis program (BCHD-TB) successfully completing latent tuberculosis infection (LTBI) treatment, as compared to other referral groups, and to identify factors associated with treatment completion...

Activism on rifapentine pricing: removing cost barriers to improve the uptake of tuberculosis research innovations

Post Date: 
2014-12-21
Publication: 
Public Health Action
As recent advances have been made in developing tools to fight tuberculosis (TB), there is also a trend towards increasing advocacy by the civil society for TB research and access. One recent successful effort to increase access to treatment options for TB involved a collaborative effort to...

Leveraging information technology to address the health workforce gap

Post Date: 
2013-11-01
Publication: 
Bulletin of the World Health Organization
According to some estimates, the world needs more than 4 million additional physicians, nurses, pharmacists, laboratory technicians, midwives, community health workers (CHWs) and other front-line health workers. However, there is also a shortage of faculty that can provide high-quality training and...

HIV/AIDS education in traditional Indian systems of medicine: faculty perspectives

Post Date: 
2013-10-24
Publication: 
Journal of Traditional Medicine and and Clinical Naturopathy
Country: 
In India, HIV-infected individuals face numerous challenges in their search for treatments. Currently, western allopathic medicine (hereinafter ‘biomedicine’) offers antiretroviral therapy (ART) for HIV/AIDS and associated co-morbidities that have prolonged survival and improved quality of life...

A qualitative study of barriers to enrollment into free HIV care: perspectives of never-in-care HIV-positive patients and providers in Rakai, Uganda

Post Date: 
2013-07-23
Publication: 
BioMed Research International
Country: 
Background: Early entry into HIV care is low in Sub-Saharan Africa. In Rakai, about a third (31.5%) of HIV-positive clients who knew their serostatus did not enroll into free care services. This qualitative study explored barriers to entry into care from HIV-positive clients who had never enrolled...

Combination implementation for HIV prevention: moving from evidence to population-level impact

Post Date: 
2013-01-15
Publication: 
The Lancet Infectious Disease
The promise of combination HIV prevention-the application of multiple HIV prevention interventions to maximise population-level effects-has never been greater. However, to succeed in achieving significant reductions in HIV incidence, an additional concept needs to be considered: combination...

Household-based HIV counseling and testing as a platform for referral to HIV care and medical male circumcision in Uganda: a pilot evaluation

Post Date: 
2012-12-13
Publication: 
PLOS One
Country: 
Background: Combination HIV prevention initiatives incorporate evidence-based, biomedical and behavioral interventions appropriate and acceptable to specific populations, aiming to significantly reduce population-level HIV incidence. Knowledge of HIV serostatus is key to linkages to HIV care and...

Evaluation of a multimodal, distance learning HIV management course for clinical care providers in India

Post Date: 
2012-10-01
Publication: 
Journal of the International Association of Providers of AIDS Care
Country: 
Distance learning is an important tool for training HIV health workers. However, there is limited evidence on design and evaluation of distance learning HIV curricula and tools. We therefore designed, implemented, and evaluated a distance learning course on HIV management for clinical care...

Cost analyses of peer health worker and mHealth support interventions for improving AIDS care in Rakai, Uganda

Post Date: 
2012-09-12
Publication: 
AIDS Care
Country: 
A cost analysis study calculates resources needed to deliver an intervention and can provide useful information on affordability for service providers and policy-makers. We conducted cost analyses of both a peer health worker (PHW) and a mHealth (mobile phone) support intervention. Excluding...

Guidelines for improving entry into and retention in care and antiretroviral adherence for persons with HIV: evidence-based recommendations from an International Association of Physicians in AIDS Care panel

Post Date: 
2012-06-05
Publication: 
Annals of Internal Medicine
Description: After HIV diagnosis, timely entry into HIV medical care and retention in that care are essential to the provision of effective antiretroviral therapy (ART). ART adherence is among the key determinants of successful HIV treatment outcome and is essential to minimize the emergence of...

Peer Health Workers and AIDS Care in Rakai, Uganda: A mixed methods operations research evaluation of a cluster-randomized trial

Post Date: 
2011-12-15
Publication: 
AIDS Patient Care and STDs
Country: 
Settings with limited health care workers are challenging environments for delivery of antiretroviral therapy. One strategy to address this human resource crisis is to task shift through training selected patients as peer health workers (PHWs) to provide care to other individuals receiving...

Impact of a mHealth intervention for peer health workers on AIDS Care in rural Uganda: a mixed methods evaluation of a cluster-randomized trial

Post Date: 
2011-11-15
Publication: 
AIDS and Behavior
Country: 
Mobile phone access in low and middle-income countries is rapidly expanding and offers an opportunity to leverage limited human resources for health. We conducted a mixed methods evaluation of a cluster-randomized trial exploratory substudy on the impact of a mHealth (mobile phone) support...

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