Publications - India

How feasible is pharmaceutical regulation in India?

Post Date: 
2018-01-29
Publication: 
The Lancet Global Health
Country: 
Lancet Global Health: This letter by Dr. Sachin Atre outlines factors that complicate pharmaceutical regulation in India, which is a component of WHO's Global Antimicrobial Resistance Action Plan.

Gender-based violence screening methods preferred by women visiting a public hospital in Pune, India

Post Date: 
2018-01-22
Publication: 
BMC Womens Health
Country: 
BMC Womens Health : In our study, 23% of women reported experiencing gender based violence, and 90% reported they had never been asked about it in the healthcare setting.

Secondhand smoke exposure and validity of self-report in low-income women and children in India

Post Date: 
2018-01-10
Publication: 
Pediatrics
Country: 
Pediatrics: Dr. Jessica Elf and colleagues evaluated the validity of standard self-reported measures for secondhand smoke (SHS) exposure among women and children in urban India.

Isoniazid concentrations in hair and plasma area-under-the-curve exposure among children with tuberculosis

Post Date: 
2017-12-07
Publication: 
PLOS One
Country: 
PLOS One: Mave and colleagues compared TB drug exposure in plasma and hair samples among a small cohort of children.

Antibiotic utilization and the role of suspected and diagnosed mosquito borne illness among adults and children with acute febrile illness in Pune, India

Post Date: 
2017-12-04
Publication: 
Clinical Infectious Diseases
Country: 
Mosquito-borne disease identification is associated with reduced empiric antibiotic use and faster antibiotic discontinuation.

Suboptimal anti-tuberculosis drug concentrations and outcomes in small and HIV coinfected children in India: recommendations for dose modifications

Post Date: 
2017-12-01
Publication: 
Clinical Pharmacology and Therapeutics
Country: 
This work aimed to evaluate the once-daily anti-tuberculosis treatment as recommended by the new Indian pediatric guidelines. Isoniazid, rifampin and pyrazinamide concentration-time profiles and treatment outcome were obtained from 161 Indian children with drug-sensitive tuberculosis undergoing...

Prevalence of dysglycemia and clinical presentation of pulmonary tuberculosis in Western India

Post Date: 
2017-12-01
Publication: 
International Journal of Tuberculosis and Lung Disease
Country: 
Objectives: To estimate the prevalence and risk factors of pre-diabetes mellitus (DM) and DM, and its associations with the clinical presentation of tuberculosis (TB). Design: Screening for DM was conducted among adults (age  18 years) with confirmed TB between December 2013 and January 2017. We...

Risk factors for early mortality on antiretroviral therapy in advanced HIV-infected adults

Post Date: 
2017-10-23
Publication: 
AIDS
Country: 
Background: Many HIV-infected individuals present with advanced HIV disease. These patients are at high risk of death after antiretroviral therapy (ART) initiation, but risk factors for death in these patients are unclear. Methods: We used data from a multisite randomized trial comparing empiric vs...

Cardiovascular risk in an HIV-infected population in India

Post Date: 
2017-07-03
Publication: 
Heart Asia
Country: 
Findings: HIV+ Indian patients who had cardiovascular disease at a younger age appear to be at imminent risk for morbidity.

A qualitative study exploring factors influencing clinical decision-making for influenza-like illness in Solapur city, Maharashtra, India

Post Date: 
2017-07-03
Publication: 
Anthropology and Medicine
Country: 
Abstract The co-existence of different types of medical systems (medical pluralism) is a typical feature of India's healthcare system. For conditions such as influenza-like illness (ILI), where non-specific disease signs/symptoms exist, clinical reasoning in the context of medical pluralism becomes...

Household food insecurity is associated with low interferon-gamma levels in pregnant Indian women

Post Date: 
2017-07-01
Publication: 
International Journal of Tuberculosis and Lung Disease
Country: 
Objective: To determine the association between household food insecurity and interferon-gamma (IFN-γ) levels in pregnancy. Design: Pregnant women in India were administered the Household Food Insecurity Access Scale (HFIAS) questionnaire and underwent an IFN-γ release assay. Logistic regression...

Vitamin A and D deficiencies associated with incident tuberculosis in HIV-infected patients initiating antiretroviral therapy in multinational case-cohort study

Post Date: 
2017-07-01
Publication: 
Journal of Acquired Immune Deficiency Syndromes
Country: 
Introduction: Numerous micronutrients have immunomodulatory roles that may influence risk of tuberculosis (TB), but the association between baseline micronutrient deficiencies and incident TB after antiretroviral therapy (ART) initiation in HIV-infected individuals is not well characterized...

Constituent variation in smokeless tobacco purchased in Mumbai, India

Post Date: 
2017-07-01
Publication: 
Tobacco Regulatory Science
Country: 
Objectives: Worldwide, smokeless tobacco products vary greatly in their formulations and chemical composition. Understanding of toxic and carcinogenic constituent variations in such products can provide valuable insights for the development of effective tobacco control policies. In this study, we...

Maternal syphilis: An independent risk factor for mother to infant human immunodeficiency virus transmission

Post Date: 
2017-06-15
Publication: 
Sexually Transmitted Diseases
Country: 
Abstract Syphilis is associated with increased human immunodeficiency virus acquisition and sexual transmission; we examined impact on human immunodeficiency virus mother-to-child transmission among mother-infant pairs enrolled in the India Six-Week Extended-Dose Nevirapine study. Maternal syphilis...

Tuberculosis screening among persons with diabetes mellitus in Pune, India

Post Date: 
2017-06-02
Publication: 
BMC Infectious Diseases
Country: 
Background: Diabetes mellitus (DM) increases tuberculosis (TB) risk, and there is increasing concern over the public health implications of the convergence of these two epidemics. Screening for TB among people with DM is now recommended in India. Methods: People with DM seeking care at a large...

Resident doctors' attitudes toward tuberculosis patients

Post Date: 
2017-04-15
Publication: 
Indian Journal of Tuberculosis
Country: 
Background: The attitude of the resident doctors toward tuberculosis (TB) patients can affect their treatment seeking behavior, compliance to treatment as well as reinforce the stigma attached to the disease by the society at large. Aims: To assess the attitudes of resident medical doctors toward...

High burden of antimicrobial resistance and mortality among adults and children with community-onset bacterial infections in India

Post Date: 
2017-04-15
Publication: 
Journal of Infectious Diseases
Country: 
Of 133 isolates from 115 patients, 50% were multi-drug resistant; of 33 isolates tested for carbapenem susceptibility, 36% were resistant.

Novel interferon-gamma assays for diagnosing tuberculosis in young children in India

Post Date: 
2017-04-01
Publication: 
International Journal of Tuberculosis and Lung Disease
Country: 
Setting: The tuberculin skin test (TST) and interferon-gamma release assays (IGRAs) are used as supportive evidence to diagnose active tuberculosis (TB). Novel IGRAs could improve diagnosis, but data are lacking in young children. Design: Children (age 5 years or younger) with suspected TB were...

High prevalence of cryptococcal antigenaemia amongst asymptomatic advanced HIV patients in Pune, India

Post Date: 
2017-03-21
Publication: 
Indian Journal of Medical Microbiology
Country: 
Methods : A prospective study was conducted in a large public sector ART centre and the inpatient wards of Sassoon Hospital, Pune, India. All consenting patients> 18 years of age with CD4 count <100 cells/mm3 were screened for CrAg by latex agglutination assay. Those with positive CrAg...

Modelling approaches for tuberculosis: are they realistic?

Post Date: 
2017-03-01
Publication: 
The Lancet Global Health
Country: 
Letter by Dr. Sachin Atre in The Lancet Global Health.

Pages