RePORT International: advancing tuberculosis biomarker research through global collaboration

Post Date: 
2015-10-15
Publication: 
Clinical Infectious Diseases
Clinical Site(s): 
Country: 
Summary: 
Progress in tuberculosis clinical research is hampered by a lack of reliable biomarkers that predict progression from latent to active tuberculosis, and subsequent cure, relapse, or failure. Regional Prospective Observational Research for Tuberculosis (RePORT) International represents a consortium of regional cohorts (RePORT India, RePORT Brazil, and RePORT Indonesia) that are linked through the implementation of a Common Protocol for data and specimen collection, and are poised to address this critical research need. Each RePORT network is designed to support local, in-country tuberculosis-specific data and specimen biorepositories, and associated research. Taken together, the expected results include greater global clinical research capacity in high-burden settings, and increased local access to quality data and specimens for members of each network and their domestic and international collaborators. Additional networks are expected to be added, helping to spur tuberculosis treatment and prevention research around the world.
Citation: 
Hamilton CD, Swaminathan S, Christopher DJ, Ellner J, Gupta A, Sterling TR, Rolla V, Srinivasan S, Karyana M, Siddiqui S, Stoszek SK, Kim P. RePORT International: advancing tuberculosis biomarker research through global collaboration. Clinical Infectious Diseases. 2015;61(suppl 3):S155-S159 doi: 10.1093/cid/civ611.
Collaborators: 
Scientific Affairs, Global Health, Population and Nutrition, FHI 360
Department of Medicine, Division of Infectious Diseases, Duke University School of Medicine, Durham, NC
Department of Clinical Research, National Institute for Research in Tuberculosis, Chennai and Pune, India
Pulmonary Medicine, Christian Medical College, Vellore, India
School of Medicine, Boston University, MA
School of Medicine, Johns Hopkins University, Baltimore, MD
Department of Medicine, Division of Infectious Diseases, Vanderbilt University School of Medicine, Nashville, TN
National Institute of Infectious Diseases Evandro Chagas–Fiocruz, Rio de Janeiro, Brazil
Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health
Collaborative Clinical Research Branch, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health
Health Studies Sector, Westat, Rockville, MD
The National Institute of Research and Development, Indonesia Ministry of Health, Jakarta, Indonesia