Study/Projects - Maternal and child health

P2010: Phase III Study of the Virologic Efficacy and Safety of Dolutegravir-Containing versus Efavirenz-Containing Antiretroviral Therapy Regimens in HIV-1-Infected Pregnant Women and their Infants “VESTED”

Post Date: 
2018-01-30
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Title: P2010: Phase III Study of the Virologic Efficacy and Safety of Dolutegravir-Containing versus Efavirenz-Containing Antiretroviral Therapy Regimens in HIV-1-Infected Pregnant Women and their Infants “VESTED”: V irologic E fficacy and S afety of ART Combinations with T AF/TDF, E FV, and D TG...

Zika Surveillance among Antenatal Clinic Outpatients in BJ Government Medical College and Sassoon General Hospitals, Pune, India

Post Date: 
2017-08-31
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CCGHE is keeping an eye on Zika among pregnant women, which is transmitted by mosquitoes & can cause devastating birth defects.

TB and Pregnancy Impact of Immune Changes of HIV and Stages of Pregnancy on Tuberculosis: Nested Study on Investigating Maternal Antibodies to Modify Infant Tuberculosis Acquisition

Post Date: 
2017-08-29
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New study in Pune, India, aims to identify the profile of TB antibodies between mothers and infants, and to see if the presence of antibodies lowers risk of infant infection.

Bacterial Antimicrobial Resistance Patterns in Pune, India: Substudy on Community Health-Seeking Behavior Among Patients Admitted with Acute Febrile Illness

Post Date: 
2015-05-28
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Objectives: To describe the patterns of health-care seeking behavior and prior outpatient care among patients admitted with acute febrile illness to Sassoon Hospital To determine the effects of outpatient behaviors and prior treatments on the antimicrobial resistance patterns of stool colonizing...

Barriers for Intervention to Prevent Occupationally Acquired Tuberculosis in Healthcare Workers

Post Date: 
2015-05-21
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This study was funded by the Fogarty International Center at the U.S. National Institutes of Health. Observational study to assess the current status of implementation of interventions for preventing occupationally acquired TB in HCW. Identify the barriers to implementing these interventions

P1078: A Phase IV Randomized Double-Blind Placebo-Controlled Trial to Evaluate the Safety of Immediate (Antepartum-Initiated) Versus Deferred (Postpartum-Initiated) Isoniazid Preventive Therapy Among HIV-Infected Women in High TB Incidence Settings

Post Date: 
2014-04-01
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Dr. Amita Gupta is Protocol Chair for this multinational clinical trial being conducted in Botswana, Haiti, South Africa, Tanzania, Thailand, Uganda, and Zimbabwe, and in India by the Baltimore-Washington-India Clinical Trials Unit, of which CCGHE is a member. Background Tuberculosis (TB) is the...

RePORT: C-TRIUMPH: Substudy on Assessing the Association of Indoor Air Pollution with Tuberculosis in Adult Women and Children under 5 Years of Age

Post Date: 
2013-09-15
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Addressing social and environmental risk factors contributing to TB disease is becoming increasingly important for national TB programs. We are leveraging the pediatric participants in 1,100 homes participating in the C-TRIUMPH study, enhancing data collection regarding household and individual...

Community Home Based India Prevention of Mother to Child Transmission of HIV (COMBIND)

Post Date: 
2013-09-02
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CCGHE is assessing whether equipping Community Health Workers with mobile health technology and involving them in technology training and personal empowerment seminars can help prevent mother-to-child transmission of HIV. CHWs who care for HIV + pregnant and nursing women are using the emocha...

P1077BF: Breastfeeding Version of the PROMISE Study (Promoting Maternal and Infant Survival Everywhere)

Post Date: 
2010-02-02
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This multi-country trial is being conducted in India, Malawi, South Africa, Tanzania, Uganda, Zambia, and Zimbabwe. 1077BF is a randomized strategy trial, which is part of the PROMISE studies (1077BF, 1077FF, P1084s, and 1077HS). The Promoting Maternal and Infant Survival Everywhere (PROMISE)...

P1077FF: Formula Feeding Version of the PROMISE Study (Promoting Maternal and Infant Survival Everywhere)

Post Date: 
2010-02-02
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This multi-country trial is being conducted in India, Malawi, South Africa, Tanzania, Uganda, Zambia, and Zimbabwe. 1077FF is a randomized strategy trial, which is part of the PROMISE studies (1077BF, 1077FF, P1084s, and 1077HS). The Promoting Maternal and Infant Survival Everywhere (PROMISE)...

Immunomodulatory Properties of BCG: Implications for MTCT

Post Date: 
2008-06-01
To evaluate the immune activating properties of BCG vaccination in neonatal CD4 cells and test the hypothesis that neonatal BCG vaccination leads to activation of immune response that may increase the susceptibility to HIV infection in breast-fed infants of HIV-positive mothers.

BWI CTU: Baltimore-Washington-India Clinical Trials Unit

Post Date: 
2007-02-02
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Comprising clinical trial sites at Johns Hopkins Medicine in Baltimore, Whitman Walker Health in Washington, DC, and the BJGMC-CCGHE collaboration in Pune, India, the Baltimore-Washington-India Clinical Trials Unit (BWI-CTU) is one of only 25 international HIV/TB clinical trial sites funded by the...

BJGMC-JHU Fogarty HIV-TB Training Program

Post Date: 
2007-01-01
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Funded by the Fogarty International Center at the National Institutes of Health, the JHU Fogarty program has nearly 20 years of success with providing training, professional development, and mentorship to clinicians and scientists in low and middle income countries. CCGHE's latest efforts in this...

Integration of HIV and Other Prevalent Relevant Infectious Disease Care into Primary Medical Care

Post Date: 
2007-01-01
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According to the Pan American Health Organization (PAHO), HIV is rapidly expanding in Latin America, and among the Latin American countries with highest HIV prevalence, four are located in Central America. Notably, AIDS is among the 10 leading causes of death in three of the six countries in...

P1060: Phase II, parallel, randomized, clinical trials comparing the responses to initiation of NNRTI-based antiretroviral therapy in HIV-infected infants who have not previously received Single dose Nevirapine for prevention of Mother-to-child HIV...

Post Date: 
2006-03-27
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This study ended June 28, 2015. Full Title: Phase II, Parallel, Randomized, Clinical Trials Comparing the Responses to Initiation of NNRTI-Based Versus PI-Based Antiretroviral Therapy in HIV-Infected Infants Who Have and Have Not Previously Received Single Dose Nevirapine for Prevention of Mother-...

Mother-to-Child Transmission (MTCT) of HIV: India SWEN Study

Post Date: 
2002-06-07
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This study was officially terminated August 2018. Primary and secondary analyses of the India SWEN study, an NIH-funded phase III randomized controlled trial of an extended nevirapine prophylaxis regimen among 783 HIV-infected pregnant women and their breastfed infants in Pune, India.