Mallika Alexander, MBBS

Pune, India
Role: 
Staff
Project Manager
Mallika Alexander, MBBS

Dr. Alexander is the project manager for the PRACHITi study, a study on immunological changes in HIV positive and negative pregnant women with latent tuberculosis at Byramjee Jeejeebhoy Government Medical College Clinical Research Site (BJGMC-CRS) in Pune, India. A gynecologist by training, her research interests are improving women’s health, prevention of HIV and AIDS, microbicides, and HPV related cancers.

She has more than 30 years of multidisciplinary experience. Prior to joining BJGMC-CRS, she was the medical manager at National AIDS Research Institute (NARI) for eight years, where she managed implementation of clinical trial studies under the NIH HIV Prevention Trial Network (HPTN), Adult AIDS Clinical Trails Group (ACTG) and Microbicide Trial Network (MTN). She was the Investigator of Record (IoR) for the safety and acceptability of nonmedicated vaginal ring trial study (MTN 005). While she was at NARI, she led the regulatory cell ensuring that the clinical trials were conducted within the framework of Good Clinical Practice and Ethical principles. She also worked as a research scientist at KEM Hospital Research Centre (KEMHRC) for 15 years, where she implemented hospital-based and community-based research studies under the aegis of the Indian Council of Medical Research. Some of the important clinical research studies implemented include the Prevalence of Reproductive Tract Infections in Low Risk and High Risk Women in Pune, and the Phase II b Clinical Trial of Norplant 1, etc.

While at KEM HRC, she spearheaded social science research funded by Population Council, India, on the sexual behavior of over 8000 adolescents and youth in urban and rural Pune, a little researched topic in an era of pandemic HIV. She followed this up with interventional research funded by DFID, India, for improving parent-child communication on sexual and reproductive health—an area identified as needing interventions.

Other sphere of her work was improving skills of primary healthcare providers at public health facilities at the village, district, and state level in Maharashtra, India. She conducted hands-on training on maternal and child health for medical officers and paramedical workers at primary health centers (PHC) as well as district level and state level trainers.

She obtained her MBBS degree from Christian Medical College (CMC), Vellore, and a Diploma in obstetrics and gynecology from Bharathidasan University, India. After graduating she worked as a resident gynecologist for seven years at a mission hospital in interiors of Maharashtra, serving 30 villages. She has published scientific articles in peer reviewed journals and has presented papers in national and international conferences.

Zika Surveillance among Antenatal Clinic Outpatients in BJ Government Medical College and Sassoon General Hospitals, Pune, India

Post Date: 
2017-08-31
Country: 
CCGHE is keeping an eye on Zika among pregnant women, which is transmitted by mosquitoes & can cause devastating birth defects.

TB and Pregnancy Impact of Immune Changes of HIV and Stages of Pregnancy on Tuberculosis: Nested Study on Investigating Maternal Antibodies to Modify Infant Tuberculosis Acquisition

Post Date: 
2017-08-29
Country: 
New study in Pune, India, aims to identify the profile of TB antibodies between mothers and infants, and to see if the presence of antibodies lowers risk of infant infection.

Vaginal Microbiota in HIV Infected Pregnant Women

Post Date: 
2017-07-14
Country: 
Led by Dr. Rupak Shivakoti, this is a nested cross-sectional study of 30 HIV-infected and 60 non-HIV infected pregnant women. Pregnant women that are part of the parent study (“Impact of Immune Changes of HIV and Stages of Pregnancy on Tuberculosis” referred to as PRACHITI study from here on) will...

Maternal Inflammation, Diet and Gut Microbiome in HIV: Impact on Infant Outcomes

Post Date: 
2016-07-01
Country: 
The primary objective of this study is to determine the feasibility and operational logistics of collecting stool for microbiome analysis, detailed nutritional assessment using a food-frequency questionnaire for dietary intake and serum for inflammatory markers in order to determine factors that...

TB and Pregnancy Impact of Immune Changes of HIV and Stages of Pregnancy on Tuberculosis

Post Date: 
2014-09-01
Country: 
Purpose: TB is a leading cause of maternal mortality, especially among HIV-infected women. Women are most likely to develop active TB during and immediately after pregnancy. The immunologic conditions responsible for this phenomenon are not understood. Our recent research shows that pregnant women...

BWI CTU: Baltimore-Washington-India Clinical Trials Unit

Post Date: 
2007-02-02
Comprising clinical trial sites at Johns Hopkins Medicine in Baltimore, Whitman Walker Health in Washington, DC, and the BJGMC-CCGHE collaboration in Pune, India, the Baltimore-Washington-India Clinical Trials Unit (BWI-CTU) is one of only 25 international HIV/TB clinical trial sites funded by the...

Impact of Immune Changes of Pregnancy and HIV Infection on Tuberculosis

Post Date: 
2017-02-03
Presentation Location: 
Hyderabad, India
Country: 
Event & Convener: 
6th Annual Regional Prospective Observational Research for Tuberculosis (RePORT) India Joint Leadership Meeting
Poster presentation. Mathad J, Alexander M , Bhosale R, Naik S, Shivakoti R, Mave V, Suryavanshi N, Gupte N, Kulkarni V, Pradan N, Patil N, Gupta A

Shivani Mehta

Baltimore, Maryland
Shivani Mehta is a BS/BA candidate (2018) in public health at the Johns Hopkins Krieger School of Arts and Sciences, who is working with Drs. Rupak Shivakoti and Mallika Alexander on Maternal Inflammation, Diet and Gut Microbiome in HIV: Impact on Infant Outcomes. Ms. Mehta spent June and July 2016 at BJGMC in Pune, India, working under Dr. Alexander. Awards 2016 Global Health Established Field Placement Grant 2016 Johns Hopkins Provost Undergradulate Research Award for 2016-17 From Ms. Mehta's Field Report: This week, as the patients come in, I have been sitting with the counselors and...

Prarthana Vasudevan

Baltimore, Maryland
Prar Vasudevan is an international health graduate student at the Johns Hopkins School of Public Health. In Autumn 2015, she conducted a field placement in Pune, India, at BJGMC under Dr. Vidya Mave, where she worked on the study titled Maternal Inflammation, Diet and Gut Microbiome in HIV: Impact on Infant Outcomes. She is a 2015 recipient of the Global Health Established Field Placement Grant. From Prar Vasudevan's Field Report: At BJMC, I had the opportunity to make rounds in the hospital’s ART Clinic, Labor & Delivery wards, and children’s wards. I was immediately struck by the fact...

World AIDS Day 2016 at BJGMC

Post Date: 
2016-12-06
Read more about 2016 World AIDS Day activities at the BJGMC Clinical Site in Pune, India.