Mallika Alexander, MBBS

Pune, India
Role: 
Staff
Project Manager
Mallika Alexander, MBBS

Dr. Alexander is the project manager for the PRACHITi study, a study on immunological changes in HIV positive and negative pregnant women with latent tuberculosis at Byramjee Jeejeebhoy Government Medical College Clinical Research Site (BJGMC-CRS) in Pune, India. A gynecologist by training, her research interests are improving women’s health, prevention of HIV and AIDS, microbicides, and HPV related cancers.

She has more than 30 years of multidisciplinary experience. Prior to joining BJGMC-CRS, she was the medical manager at National AIDS Research Institute (NARI) for eight years, where she managed implementation of clinical trial studies under the NIH HIV Prevention Trial Network (HPTN), Adult AIDS Clinical Trails Group (ACTG) and Microbicide Trial Network (MTN). She was the Investigator of Record (IoR) for the safety and acceptability of nonmedicated vaginal ring trial study (MTN 005). While she was at NARI, she led the regulatory cell ensuring that the clinical trials were conducted within the framework of Good Clinical Practice and Ethical principles. She also worked as a research scientist at KEM Hospital Research Centre (KEMHRC) for 15 years, where she implemented hospital-based and community-based research studies under the aegis of the Indian Council of Medical Research. Some of the important clinical research studies implemented include the Prevalence of Reproductive Tract Infections in Low Risk and High Risk Women in Pune, and the Phase II b Clinical Trial of Norplant 1, etc.

While at KEM HRC, she spearheaded social science research funded by Population Council, India, on the sexual behavior of over 8000 adolescents and youth in urban and rural Pune, a little researched topic in an era of pandemic HIV. She followed this up with interventional research funded by DFID, India, for improving parent-child communication on sexual and reproductive health—an area identified as needing interventions.

Other sphere of her work was improving skills of primary healthcare providers at public health facilities at the village, district, and state level in Maharashtra, India. She conducted hands-on training on maternal and child health for medical officers and paramedical workers at primary health centers (PHC) as well as district level and state level trainers.

She obtained her MBBS degree from Christian Medical College (CMC), Vellore, and a Diploma in obstetrics and gynecology from Bharathidasan University, India. After graduating she worked as a resident gynecologist for seven years at a mission hospital in interiors of Maharashtra, serving 30 villages. She has published scientific articles in peer reviewed journals and has presented papers in national and international conferences.

Gut Microbiota of HIV Infected Pregnant Women

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2018-06-14
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Birth Outcomes in HIV Both antiretroviral-therapy (ART)-naïve and ART-experienced HIV-infected pregnant women have higher incidences of pre-term birth (PTB) compared to HIV-uninfected women. For example, the global prevalence of PTB is around 8%, while the rates in in HIV-infected populations are...

Zika Surveillance among Antenatal Clinic Outpatients in BJ Government Medical College and Sassoon General Hospitals, Pune, India

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2017-08-31
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CCGHE is keeping an eye on Zika among pregnant women, which is transmitted by mosquitoes & can cause devastating birth defects.

TB and Pregnancy Impact of Immune Changes of HIV and Stages of Pregnancy on Tuberculosis: Nested Study on Investigating Maternal Antibodies to Modify Infant Tuberculosis Acquisition

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2017-08-29
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New study in Pune, India, aims to identify the profile of TB antibodies between mothers and infants, and to see if the presence of antibodies lowers risk of infant infection.

Vaginal Microbiota in HIV Infected Pregnant Women

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2017-07-14
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Led by Dr. Rupak Shivakoti, this is a nested cross-sectional study of 30 HIV-infected and 60 non-HIV infected pregnant women. Pregnant women that are part of the parent study (“Impact of Immune Changes of HIV and Stages of Pregnancy on Tuberculosis” referred to as PRACHITI study from here on) will...

TB and Pregnancy Impact of Immune Changes of HIV and Stages of Pregnancy on Tuberculosis

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2014-09-01
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This is a cross sectional observational study known as PRACHITi (PRegnancy And CHanges In Tuberculosis), Purpose: TB is a leading cause of maternal mortality, especially among HIV-infected women. Women are most likely to develop active TB during and immediately after pregnancy. The immunologic...

BWI CTU: Baltimore-Washington-India Clinical Trials Unit

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2007-02-02
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Comprising clinical trial sites at Johns Hopkins Medicine in Baltimore, Whitman Walker Health in Washington, DC, and the BJGMC-CCGHE collaboration in Pune, India, the Baltimore-Washington-India Clinical Trials Unit (BWI-CTU) is one of only 25 international HIV/TB clinical trial sites funded by the...

Screening and diagnosis of gestational diabetes in India: A systematic review and meta analysis

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2018-03-26
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Acta Diabetologica
Review article on prevalence and screening and diagnostic methods for gestational diabetes in India.

Gestational Diabetes Suppresses the Inflammatory Response to M. tuberculosis in Pregnant Women in Pune, India. Session: Clinical Investigation for TB and Diabetes

Post Date: 
2018-10-27
Mathad J, Alexander M, Bhosale R, Shere D, Kulkarni V, Kumar P, Babu S, Gupta A for the PRACHITi Study team. Gestational Diabetes Suppresses the Inflammatory Response to M. tuberculosis in Pregnant Women in Pune, India. Session: Clinical Investigation for TB and Diabetes. 49th Annual Union World...

Perinatal Depression among HIV and TB Infected and Uninfected Women in an Urban Slum in India: Prevalence and Associated Birth Outcomes

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2018-10-04
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Grossman TB , Bhosale R, Alexander M, Suryavanshi N, Mave V, Jain D, Patil NU, Gupta A, Mathad JS. Perinatal depression among HIV and TB infected and uninfected women in an urban slum in India: prevalence and associated birth outcomes. IDSA. ID Week 2018. San Francisco, CA. October 3-7, 2018.

High Prevalence of Dengue among Pregnant Women in India

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2018-08-27
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Alexander M, Naik S, Robinson M , Sapkal G, Deshpande P, Kulkarni V, Nimkar S, Sambarey P, Kinikar A, Mave V, Suryavanshi N, Gupte N, Bollinger R, Gupta A, Bharadwaj R, Mathad J. High Prevalence of Dengue among Pregnant Women in India. 2018 International Conference on Emerging Infectious Diseases...

The Effect of HIV on the Immune Response to Myobacterium tuberculosis in Pregnant Women from Pune, India.

Post Date: 
2018-02-15
Mathad J, Alexander M, Bhosale R, Naik S, Suryavanshi N, Mave V, Deshpande P, Balasubramanian U, Kulkarni V, Kumar P, Babu S, Gupte N, Nevrekar N, Patil S, Chandanwale A, Gupta A. The Effect of HIV on the Immune Response to Myobacterium tuberculosis in Pregnant Women from Pune, India. RePORT India...

Impact of Immune Changes of Pregnancy and HIV Infection on Tuberculosis

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2017-02-03
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Mathad J, Alexander M , Bhosale R, Naik S, Shivakoti R, Mave V, Suryavanshi N, Gupte N, Kulkarni V, Pradan N, Patil N, Gupta A. Impact of Immune Changes of Pregnancy and HIV Infection on Tuberculosis. 6th Annual Regional Prospective Observational Research for Tuberculosis (RePORT) India Joint...

Shivani Mehta

Baltimore, Maryland
Shivani Mehta is a BS/BA candidate (2018) in public health at the Johns Hopkins Krieger School of Arts and Sciences, who is working with Drs. Rupak Shivakoti and Mallika Alexander on Maternal Inflammation, Diet and Gut Microbiome in HIV: Impact on Infant Outcomes. Ms. Mehta spent June and July 2016 at BJGMC in Pune, India, working under Dr. Alexander. Awards 2016 Global Health Established Field Placement Grant 2016 Johns Hopkins Provost Undergradulate Research Award for 2016-17 From Ms. Mehta's Field Report: This week, as the patients come in, I have been sitting with the counselors and...

Prarthana Vasudevan

Baltimore, Maryland
Prar Vasudevan is an international health graduate student at the Johns Hopkins School of Public Health. In Autumn 2015, she conducted a field placement in Pune, India, at BJGMC under Dr. Vidya Mave, where she worked on the study titled Maternal Inflammation, Diet and Gut Microbiome in HIV: Impact on Infant Outcomes. She is a 2015 recipient of the Global Health Established Field Placement Grant. From Prar Vasudevan's Field Report: At BJMC, I had the opportunity to make rounds in the hospital’s ART Clinic, Labor & Delivery wards, and children’s wards. I was immediately struck by the fact...

Test inline fields

Post Date: 
2018-06-18
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https://google.com

BJGMC Clinical Research Team Exceeds 6,000 Participant Enrollments in 4 Years

Post Date: 
2018-08-03
Group Photo, BJGMC Clinical Research Site, 2016, Pune, India
The Indo-JHU Clinical Research partnership at BJGMC in Pune, India, is now one of the top enrollers among all ACTG research sites internationally.

World AIDS Day 2016 at BJGMC

Post Date: 
2016-12-06
Read more about 2016 World AIDS Day activities at the BJGMC Clinical Site in Pune, India.