Amita Gupta, MD, MHS

Role: 
Director
Associate Professor of Medicine and Public Health

Dr. Gupta is Deputy Director of the Johns Hopkins (JH) Center for Clinical Global Health Education (CCGHE), and Associate Professor of Infectious Diseases at the JH School of Medicine, with a joint appointment in International Health at the JH Bloomberg School of Public Health.

Board certified by the American Board of Internal Medicine in infectious diseases, Dr. Gupta specializes in international public health, clinical research, and education in infectious diseases, HIV/AIDS, and tuberculosis (TB). Since 2002, her work has been focused primarily on India, where she leads several Indo-JHU research collaborations. She serves in leadership positions for the RePORT consortium for TB research, funded by the US National Institutes of Health (NIH) and the government of India, including on the RePORT International Executive Committee, as US Chair of RePORT India, and as PI of the multi-site C-TRIUMPH research consortium.

Dr. Gupta is Co-principal Investigator of the NIH-funded Baltimore-Washington-India HIV and Infectious Diseases Clinical Trials Unit (BWI-CTU), and she is an active clinical investigator in multi-country HIV/TB trials conducted by the AIDS Clinical Trials Group (ACTG) and the International Maternal Pediatric Adolescent AIDS Trials Network (IMPAACT). Additionally, she has been awarded research grants from the NIH, CDC, and several philanthropic foundations to investigate TB in children and pregnant women, malnutrition, infection and inflammation, HIV treatment outcomes, and antibiotic resistance. ​Learn about CCGHE India Research Partnerships

Dr. Gupta is an author of more than 100 peer-reviewed research publications and 7 book chapters on prevention and treatment of HIV, TB, and other infectious diseases, predominantly in low- and middle-income settings. She has also mentored more than 30 junior scientists in India and the US to run research studies and submit their own scientific findings to peer-reviewed publications.

From 2000–2002, Dr. Gupta worked in the US Public Health Service for the Centers for Disease Control and Prevention (CDC), where she was engaged in global public health projects in the US, Guatemala, Vietnam, and Micronesia.

Dr. Gupta received an undergraduate degree from MIT, a Doctor of Medicine from Harvard Medical School, and a Master of Health Sciences in clinical investigation from JH Bloomberg School of Public Health. She completed her internal medicine training at San Francisco General Hospital-University of California, San Francisco, followed by a post-doctoral fellowships with the Epidemic Intelligence Service at the US Centers for Disease Control and Prevention (Foodborne and Diarrheal Diseases) and at the JHU School of Medicine (Infectious Diseases).

Assessing Psychological Distress among Tuberculosis Patients and Their Household Members

Post Date: 
2018-07-17
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By assessing psychological distress, Indo-JHU researchers hope to better understand the correlation between depression and TB severity.

Assessing the Feasibility and Acceptability of a Computer-based Avatar-delivered Alcohol Reduction Intervention

Post Date: 
2018-07-05
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Stigma, underreporting of misuse, lack of treatment resources, and costs are barriers to alcohol treatment in India. Computer-delivered screening and intervention could help overcome many of these issues.

Molecular Signatures of Tuberculosis-Diabetes Interaction: Metabolomics Study

Post Date: 
2018-06-15
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Type 2 diabetes mellitus (DM) is an acquired host factor that increases the risk for and severity of pulmonary tuberculosis (PTB). A report published in 2007 estimated that, in India, DM accounted for 14.8% (range 7.1% to 23.8%) of PTB and 20.2% (8.3% to 41.9%) of smear-positive PTB. Emerging data...

Molecular Signatures of Tuberculosis-Diabetes Interaction: Transcriptomics Study

Post Date: 
2018-06-15
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Type 2 diabetes is an acquired host factor that increases the risk for and severity of pulmonary tuberculosis. A report published in 2007 estimated that, in India, diabetes accounted for 14.8% (range 7.1% to 23.8%) of pulmonary tuberculosis and 20.2% (8.3% to 41.9%) of smear-positive cases...

Gut Microbiota of HIV Infected Pregnant Women

Post Date: 
2018-06-14
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Birth Outcomes in HIV Both antiretroviral-therapy (ART)-naïve and ART-experienced HIV-infected pregnant women have higher incidences of pre-term birth (PTB) compared to HIV-uninfected women. For example, the global prevalence of PTB is around 8%, while the rates in in HIV-infected populations are...

Assessing Tuberculosis Transmission Dynamics, Drug Resistance and Recurrence Using Whole Genome Sequencing in Pune, India

Post Date: 
2018-06-12
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Indo-JHU researchers are using combined geospatial and genotyping methods to describe TB transmission dynamics in a hyperlocal region of Pune City in Western India.

Optimal Approach for TB Screening among HIV Infected Indian Children

Post Date: 
2018-06-11
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Determining TB status (ie, uninfected, latent, and active TB disease) is more difficult among children, particularly HIV-infected children. Diagnosis of TB disease is more difficult among HIV infected children because the signs and symptoms of the disease—such as weight loss, cough, and mild fever—...

Predictors of Resistance Emergence Evaluation in Multidrug Resistant-Tuberculosis Patients on Treatment (PREEMPT Pilot Study)

Post Date: 
2018-03-20
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Indo-JHU Clinical Resarch Partnership is participating with Brazilian colleagues in a 3-year effort led by Boston University to identify what contributes to TB drug resistance.

A Multicenter Phase II/II Double-Blind, Randomized, Placebo Controlled Study to Evaluate the Efficacy and Safety of VPM1002 in the Prevention of Tuberculosis (TB) Recurrence in Pulmonary TB Patients After Successful TB Treatment in India

Post Date: 
2018-01-23
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Dr. Vidya Mave is leading this clinical trial evaluating the safety and efficacy of a new recombinant BCG vaccine.

Perceptions of HCWs on Barriers and Opportunities to Airborne Infection Control Guideline Implementation

Post Date: 
2017-12-07
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Led by Dr. Nishi Suryavanshi, this qualitative, cross-sectional study is assessing healthcare worker (HCW) perceptions about barriers and facilitators to the uptake of airborne infection control (AIC) guidelines. Further, the study is assessing the potential barriers and opportunities to develop...

The Role of GeneXpert in Bacterial Diagnosis of Spinal Tuberculosis

Post Date: 
2017-10-26
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India has the maximum burden of tuberculosis (TB) in the world. In 2014, there were an estimated 9.6 million incident cases of TB (range, 9.1 million–10.0 million) globally, equivalent to 133 cases per 100000 population. Most of the estimated number of cases in 2014 occurred in Asia (58%) and the...

TREAT Asia: Substudy on Assessment of Cardiovascular Health Knowledge, Preventive Practices and Cardio-protective Behavior among HIV-infected Individuals in Pune, India

Post Date: 
2017-10-12
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Cardiovascular Diseases (CVD) have become one of the leading causes of death among PLWH (People Living with HIV) across the globe. The burden that CVD will pose in the imminent future for the 2.1 million HIV-infected individuals in India is currently unclear. However given that Indians have a high...

Impact of Diabetes on TB Treatment Outcomes: Nested Study: Lipid Mediators of Inflammation in TB and TB-Diabetes

Post Date: 
2017-10-02
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Studies have shown that individuals with Tuberculosis (TB) and diabetes (TB-DM) have a distinct immune profile compared to individuals with TB alone. Individuals with TB-DM have higher inflammation, a higher bacillary load, increased Th1 immune responses and a defective neutrophil and macrophage...

RePORT: C-TRIUMPH: Nested Study on Targeting Mycobacterium Tuberculosis Persisters by Enhancing Stringent Response-specific Cellular Immunity

Post Date: 
2017-09-11
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C-TRIUMPH nested study begins to see if stringent response antigen is enhanced while treating drug-susceptible TB using the first-line anti-TB regimen.

Zika Surveillance among Antenatal Clinic Outpatients in BJ Government Medical College and Sassoon General Hospitals, Pune, India

Post Date: 
2017-08-31
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CCGHE is keeping an eye on Zika among pregnant women, which is transmitted by mosquitoes & can cause devastating birth defects.

The Role of Innate Immunity in the Acquisition of Sterile Protection against TB Infection

Post Date: 
2017-08-25
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Tuberculosis (TB) is a major global health problem. Vaccines are the most powerful instruments for limiting the morbidity and mortality of infectious diseases, so the development of highly protective TB vaccines is one of the highest priorities in public health. Bacille de Calmette et Guérin (BCG...

Validation of Transcriptional Signature to Predict Active TB Disease among Advanced HIV Patients

Post Date: 
2017-08-15
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There have been tremendous advances in the diagnosis of patients with tuberculosis (TB) based on nucleic acid amplification of bacteria in the sputum. The GenXpert MTB/RIF provides results in 2 hours. However, in HIV-infected sputum smear is often negative for AFB and the sensitivity of GenXpert...

Antimicrobial Use and Diagnosis among Hospitalized Febrile Patients in Pune, India

Post Date: 
2017-08-07
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Antimicrobial resistance, a leading threat to human health, is enabled by unnecessary antibiotic use. Strategies to reduce unnecessary antibiotic use in India, the world’s largest antibiotic consumer, are urgently needed. Although most patients hospitalized in India with acute febrile illness...

Role of Specialized Pro-resolving Mediators (SPMs) on Markers of Inflammation in HIV-infected Adults

Post Date: 
2017-08-03
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Dr. Rupak Shivikoti is leading this study. There has been a surge of recent studies focusing on the role of novel lipid mediators of inflammation called specialized pro-resolving mediators (SPMs). They are produced during inflammation as a negative feedback to resolve inflammation. However, the...

RePORT: C-TRIUMPH: Nested Study on Association of Lipid Mediators of Inflammation with TB Treatment Outcomes

Post Date: 
2017-08-03
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Recent studies have shown the significant role that host lipids play in modulating immunity and disease outcomes. Prostaglandins and leukotrienes are lipids that have a pro-inflammatory role in the fight against infectious agents while Specialized Pro-resolving lipid Mediators (SPMs) including...

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Loss to follow‐up and mortality among HIV‐infected adolescents receiving antiretroviral therapy in Pune, India

Post Date: 
2018-06-25
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Publication: 
HIV Medicine
Over 6 years, one-third of HIV+ adolescents in this study discontinued medical treatment, indicating a critical need for retention counselling and closer clinical monitoring.

Developing an assessment framework for essential internal medicine subspecialty topics

Post Date: 
2018-06-15
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Publication: 
Journal of Graduate Medical Education
Our assessment framework revealed knowledge and practice gaps in tuberculosis diagnosis among internal medicine residents.

Diabetes and pre-diabetes among household contacts of tuberculosis patients in India: is it time to screen them all?

Post Date: 
2018-05-22
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Publication: 
The International Journal of Tuberculosis and Lung Disease
Authors find that screening contacts of TB patients for pre-DM/DM and linking them to care may mitigate the risk of developing tuberculosis and improve management of diabetes.

Addressing knowledge gaps and prevention for tuberculosis-infected Indian adults: a vital part of elimination

Post Date: 
2018-05-02
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Publication: 
BMC Infectious Diseases
BMC Infectious Diseases : Our survey among TB patients' household contacts with evidence of recent exposure found that knowledge is poor and families are confused about disease transmission.

Vector-borne disease is a common cause of hospitalized febrile illness in India

Post Date: 
2018-03-26
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Publication: 
American Journal of Tropical Medicine and Hygiene
Diagnostic strategies adapted for season and age may reduce diagnostic uncertainty and identify causative organisms in treatable, fatal causes of AFI.

Intestinal barrier dysfunction and microbial translocation in HIV-infected pregnant women is associated with preterm birth

Post Date: 
2018-03-24
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Publication: 
Clinical Infectious Diseases
Clinical Infectious Diseases: Select immune markers can identify women at higher risk for pre-term birth in HIV-1-infected populations; modulating gut barrier integrity and microbial translocation may have an effect.

Gender-based violence screening methods preferred by women visiting a public hospital in Pune, India

Post Date: 
2018-01-22
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Publication: 
BMC Womens Health
BMC Womens Health : In our study, 23% of women reported experiencing gender based violence, and 90% reported they had never been asked about it in the healthcare setting.

Secondhand smoke exposure and validity of self-report in low-income women and children in India

Post Date: 
2018-01-10
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Publication: 
Pediatrics
Pediatrics: Dr. Jessica Elf and colleagues evaluated the validity of standard self-reported measures for secondhand smoke (SHS) exposure among women and children in urban India.

Isoniazid concentrations in hair and plasma area-under-the-curve exposure among children with tuberculosis

Post Date: 
2017-12-07
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Publication: 
PLOS One
PLOS One: Mave and colleagues compared TB drug exposure in plasma and hair samples among a small cohort of children.

Antibiotic utilization and the role of suspected and diagnosed mosquito borne illness among adults and children with acute febrile illness in Pune, India

Post Date: 
2017-12-04
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Publication: 
Clinical Infectious Diseases
Mosquito-borne disease identification is associated with reduced empiric antibiotic use and faster antibiotic discontinuation.

Suboptimal anti-tuberculosis drug concentrations and outcomes in small and HIV coinfected children in India: recommendations for dose modifications

Post Date: 
2017-12-01
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Publication: 
Clinical Pharmacology and Therapeutics
This work aimed to evaluate the once-daily anti-tuberculosis treatment as recommended by the new Indian pediatric guidelines. Isoniazid, rifampin and pyrazinamide concentration-time profiles and treatment outcome were obtained from 161 Indian children with drug-sensitive tuberculosis undergoing...

Prevalence of dysglycemia and clinical presentation of pulmonary tuberculosis in Western India

Post Date: 
2017-12-01
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Publication: 
International Journal of Tuberculosis and Lung Disease
Objectives: To estimate the prevalence and risk factors of pre-diabetes mellitus (DM) and DM, and its associations with the clinical presentation of tuberculosis (TB). Design: Screening for DM was conducted among adults (age  18 years) with confirmed TB between December 2013 and January 2017. We...

Risk factors for early mortality on antiretroviral therapy in advanced HIV-infected adults

Post Date: 
2017-10-23
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Publication: 
AIDS
Background: Many HIV-infected individuals present with advanced HIV disease. These patients are at high risk of death after antiretroviral therapy (ART) initiation, but risk factors for death in these patients are unclear. Methods: We used data from a multisite randomized trial comparing empiric vs...

Cardiovascular risk in an HIV-infected population in India

Post Date: 
2017-07-03
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Publication: 
Heart Asia
Findings: HIV+ Indian patients who had cardiovascular disease at a younger age appear to be at imminent risk for morbidity.

Vitamin A and D deficiencies associated with incident tuberculosis in HIV-infected patients initiating antiretroviral therapy in multinational case-cohort study

Post Date: 
2017-07-01
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Publication: 
Journal of Acquired Immune Deficiency Syndromes
Introduction: Numerous micronutrients have immunomodulatory roles that may influence risk of tuberculosis (TB), but the association between baseline micronutrient deficiencies and incident TB after antiretroviral therapy (ART) initiation in HIV-infected individuals is not well characterized...

Household food insecurity is associated with low interferon-gamma levels in pregnant Indian women

Post Date: 
2017-07-01
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Publication: 
International Journal of Tuberculosis and Lung Disease
Objective: To determine the association between household food insecurity and interferon-gamma (IFN-γ) levels in pregnancy. Design: Pregnant women in India were administered the Household Food Insecurity Access Scale (HFIAS) questionnaire and underwent an IFN-γ release assay. Logistic regression...

Maternal syphilis: An independent risk factor for mother to infant human immunodeficiency virus transmission

Post Date: 
2017-06-15
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Publication: 
Sexually Transmitted Diseases
Abstract Syphilis is associated with increased human immunodeficiency virus acquisition and sexual transmission; we examined impact on human immunodeficiency virus mother-to-child transmission among mother-infant pairs enrolled in the India Six-Week Extended-Dose Nevirapine study. Maternal syphilis...

Tuberculosis screening among persons with diabetes mellitus in Pune, India

Post Date: 
2017-06-02
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Publication: 
BMC Infectious Diseases
Background: Diabetes mellitus (DM) increases tuberculosis (TB) risk, and there is increasing concern over the public health implications of the convergence of these two epidemics. Screening for TB among people with DM is now recommended in India. Methods: People with DM seeking care at a large...

Pulmonary infections in pregnancy

Post Date: 
2017-06-01
Publication: 
Seminars in Respiratory and Critical Care Medicine
Clinical review from Drs. Amita Gupta & Jyoti Mathad on improving tuberculosis treatment outcomes for pregnant women.

Treatment of pulmonary tuberculosis

Post Date: 
2017-04-27
Publication: 
Handbook of Tuberculosis
This chapter addresses the treatment of pulmonary tuberculosis highlighting drug classes, recommended regimens, adverse drug reactions, drug-drug interactions, and practical aspects of monitoring, The principles of treatment of latent tuberculosis are also addressed including whom to treat, what...

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Randomized Trial of Safety of Isoniazid Preventive Therapy During or After Pregnancy

Post Date: 
2018-03-07
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Presentation Location: 
Boston, MA
Event & Convener: 
CROI 2018
Oral Presentation. Gupta A, Montepiedra G, Aaron L, Theron G, McCarthy K, Onyango-Makumbi C, Chipate T, Masheto G, Shin K, Zimmer B, Sterling TR, Chakhtoura N, Jean-Philippe P, Weinberg A for the IMPAACT P1078/TB APPRISE Study Team.

GLP-1 and C-Peptide are Associated with Insulin Resistance among PLWH in India

Post Date: 
2018-03-07
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Presentation Location: 
Boston, MA
Event & Convener: 
CROI 2018
Poster Presentation. Marbaniang I, Sangle S, Kadam D, Kulkarni V, Shere D, Gupte N, Gupta A, Mave V

Inflammation in HIV-Infected Pregnant Women is Associated with Pre-term Birth

Post Date: 
2018-03-07
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Presentation Location: 
Boston, MA
Event & Convener: 
CROI 2018
Poster Presentation. Shivakoti R, Gupte N, Kumar NP, Kulkarni V, Balasubramanian U, Bhosale R, Sambarey P, Kinikar A, Bharadwaj R, Patil S, Inamdar S, Suryavanshi N, Babu S, Bollinger R, Gupta A

One Month of Rifapentine/Isoniazid to Prevent TB In People With HIV: Brief-TB/A5279

Post Date: 
2018-03-05
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Presentation Location: 
Boston, MA
Event & Convener: 
CROI 2018
Abstract Presentation. Swindells S, Ramchandani R, Gupta A, Benson CA, Leon-Cruz JT, Omoz-Oarhe A, Juste MAJ, Lama JR, Valencia JA, Badal-Faesen S, Moran LE, Fletcher CV, Nuermberger E, Chaisson RE.

Infection Free “Resistors” among Household Contacts of Culture-Confirmed Adult Pulmonary TB Cases

Post Date: 
2018-02-21
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Presentation Location: 
New Delhi, India
Event & Convener: 
5th Global Forum on TB Vaccines
Presentation. Mave V , Chandrasekaran P, Paradkar M, Gupte A, Pradhan N, Kannan GN, Shivakumar SVBY, Kulkarni V, Dhanasekaran K, Subramanyam B, Selvaraju S, Murali L, Bharadwaj R, Gaikwad S, Meshram S, Kinikar A, Hanna LE, Swaminathan S, Gupte N, Gupta A.

TB Infection Among Household Contacts: Preventive Therapy for All?

Post Date: 
2018-02-21
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Presentation Location: 
New Delhi, India
Event & Convener: 
5th Global Forum on TB Vaccines
Presentation. Dolla CK, Paradkar M, Gupte A, Thiruvenkadam K, Gupte N, Kulkarni A, Balasubranian U, Hanna LE, Dhanasekaran K, Bharadwaj R, Shivakumar SVBY, Gaikwad S, Meshram S, Kohli R, Lokhande R, Thomas B, Kinikar A, Swaminathan S, Mave V, Gupta A, Chandrasekaran P

Incidence of Mycobacterium tuberculosis Infection among Household Contacts of Adult Pulmonary Tuberculosis Cases in India

Post Date: 
2018-02-20
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Presentation Location: 
New Delhi, India
Event & Convener: 
5th Global Forum on TB Vaccines
Presentation. Selvaraju S, Thiruvenkadam K, Paradkar M , Marinaik SB, Bharadwaj R, Rajagopalan S, Gaikwad S, Pattabiraman S, Kinikar A, Sivaramakrishnan GN, Meshram S, Hanna LE, Lokhande R, Dhanasekaran K, Gupte A, John S, Gupte N, Thomas B, Kukarni V, Ayyanu S, Kohli R, Shivakumar SVBY,...

Interleukin-6, Interleukin-13 and Interferon-γ as Potential Biomarkers for Treatment Failure in Pulmonary Tuberculosis

Post Date: 
2018-02-15
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Countries: 
Presentation Location: 
New Delhi, India
Event & Convener: 
RePORT India Annual Meeting
Gupte A, Andrade B, Kumar P, Selvaraju S, Lokhande R, Kulkarni V, Paradkar M, Kohli R, Thiru K, Shivakumar SVBY, Gupte N, Babu S, Golub J, Mave V, Chandrasekaran P, Gupta A.

Linezolid Experience Among MDR-TB Patients in Mumbai

Post Date: 
2018-02-15
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Countries: 
Presentation Location: 
New Delhi, India
Event & Convener: 
RePORT India Annual Meeting
Oral Presentation. Tornheim JA, Ganatra S, Deluca A, Banka R, Rodrigues C, Gupta A, Udwadia ZF.

Risk Factors Associated with Unfavorable Outcomes in a Cohort of Pulmonary TB Patients

Post Date: 
2018-02-15
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Countries: 
Presentation Location: 
New Delhi, India
Event & Convener: 
RePORT India Annual Meeting
Oral Presentation. Dhanasekaran K, Chandrasekaran P, Paradkar M, Marinaik SB, Gupte A, Dolla CK, Joseph B, Subramanyam B, Sivaramakrishnan GR, Thiruvengadam K, Gupte N, Rajagopal S, Pradhan N, Selvaraju S, Kulkarni V, Hannah LE, Nayakam R, Suryavanshi N, Shivakumar SVBY, Mave V, Thomas B, Bharadwaj...

Drug Susceptibility of Rifampin-resistant Tuberculosis using Whole Genome Sequencing to Identify Genes of Interest in Pune, India

Post Date: 
2018-02-15
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Clinical Sites: 
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Countries: 
Presentation Location: 
New Delhi, India
Event & Convener: 
RePORT India Annual Meeting
Oral Presentation. Tornheim JA, Madugundu AK, Pradhan N, Bharadwaj R, Mave V, Golub J, Pandey A, Gupta A.

The Effect of HIV on the Immune Response to Myobacterium tuberculosis in Pregnant Women from Pune, India.

Post Date: 
2018-02-15
Presentation Location: 
New Delhi, India
Event & Convener: 
RePORT India Annual Meeting
Mathad J, Alexander M, Bhosale R, Naik S, Suryavanshi N, Mave V, Deshpande P, Balasubramanian U, Kulkarni V, Kumar P, Babu S, Gupte N, Nevrekar N, Patil S, Chandanwale A, Gupta A.

Incidence of Mycobacterium tuberculosis Infection among Household Contacts of Adult Pulmonary Tuberculosis Cases in India

Post Date: 
2018-02-15
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Countries: 
Presentation Location: 
New Delhi, India
Event & Convener: 
CTRIUMPh Study Team, RePORT India Annual Meeting
Paradkar M, Dhanasekaran K, Kinikar A, Kulkarni R, Bharadwaj R, Gaikwad S, Lokhande R, Meshram S, Dolla CK, Selvaraju S, Murali L, Thiruvengadam K, Jain D, Rajagopal S, Kulkarni V, Pradhan N, John S, Kohli R, Nayagam R, Shivakumar SVBY, Suryavanshi N, Cox S, Gupte A, Chandrasekaran P, Mave V, Gupta...

Poor Understanding of TB Infection among At-risk Tuberculin Skin-test Positive Household Contacts of Pulmonary TB Cases in Pune, India

Post Date: 
2018-02-15
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Countries: 
Presentation Location: 
New Delhi, India.
Event & Convener: 
RePORT India Annual Meeting
Dhumal G, DeLuca A, Paradkar M, Suryavanshi N, Mave V, Kohli R, Shivakumar SVBY, Kadam D, Gupta A.

Hyperhomocysteinemia Screening: A Missed Opportunity to Mitigate CVD Risk among Asian Indian HIV-infected Adults?

Post Date: 
2017-12-28
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Clinical Sites: 
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Countries: 
Presentation Location: 
Kolkata, India
Event & Convener: 
AAPI Global Health Summit. American Association of Physicians of Indian Origin
Poster Presentation. Marbaniang I , Sangle S, Kulkarni V, Deshpande P, Shere D, Gupte N, Gupta A, Mave V.

Leveraging Collective Impact to Promote India's Development: The Role of the Indian Diaspora in the Fight Against Tuberculosis

Post Date: 
2017-11-09
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Countries: 
Presentation Location: 
Georgetown University, Washington, DC
Event & Convener: 
Roundtable Event. USAID, American India Foundation, Dasra, Indiaspora, Intellecap
Roundtable speaker. Amita Gupta.

Lack of TB Knowledge Among TST-Positive Household Contacts of Pulmonary Cases: A Missed Opportunity

Post Date: 
2017-10-13
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Clinical Sites: 
Presentation Location: 
Guadalajara, Mexico
Event & Convener: 
48th Annual Union World Conference of Lung Health
Poster Presentation. DeLuca A , Dhumal G, Paradkar M, Suryavanshi N, Mave V, Kohli R, Shivakumar SVBY, Gupta A

The ACTG IMPAACT PHOENIx Feasibility Study: Implications for Country Programs

Post Date: 
2017-10-13
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Clinical Sites: 
Presentation Location: 
Guadalajara, Mexico
Event & Convener: 
48th Annual Union World Conference of Lung Health
Symposium Speaker: Post-exposure Management of Households Exposed to Drug-resistant Tuberculosis: Lessons from the Field. Gupta A

Accessing MDR-TB Exposed Households: the PHOENiX MDR-TB Feasibility Study

Post Date: 
2017-10-13
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Clinical Sites: 
Presentation Location: 
Guadalajara, Mexico
Event & Convener: 
48th Annual Union World Conference of Lung Health
Symposium Speaker: Post-exposure Management of Households Exposed to Drug-resistant Tuberculosis: Lessons from the Field. Gupta A

Meet the Expert: Managing Tuberculosis in Pregnant Women and Newborns

Post Date: 
2017-10-13
Presentation Location: 
Guadalajara, Mexico
Event & Convener: 
48th Annual Union World Conference of Lung Health
Meet the Expert Session. Gupta A.

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Geeta Shrikar Pardeshi, MD

BJGMC-JHU Fogarty HIV-TB Program Trainee
Pune, India
Dr. Geeta Shrikar Pardeshi
I have led research projects related to Reproductive and Child Health, Sanitation and Infectious diseases. As part of the BJGMC JHU Fogarty training program in HIV-TB, I have research interest in TB epidemiology. I am interested in studying the association of co-morbidities with clinical presentation and treatment outcomes in tuberculosis.

Sunita Girish, PhD

BJGMC-JHU Fogarty HIV-TB Program Trainee
Pune, India
Education : Ph.D, Pune University, 2005 (Medical Biochemistry) title “Antioxidant Status in Leprosy.” Overview : How to improve health systems to combat various infectious diseases like Leprosy, Tuberculosis and HIV in developing countries, is a research and policy issue that affects many aspects of public health. My research interests include further to understand molecular level changes in cystic fibrosis which is under diagnosed .My interests also involve innovations in molecular techniques dealing with infectious diseases, help governments in developing countries to improve and modify...

Akshay Gupte, PhD, MBBS, MSPH

Junior Investigator
Akshay Gupte
Akshay Gupte is a junior investigator trained in medicine, clinical research, and global health. He recently completed his doctoral training in the Department of International Health at the Johns Hopkins Bloomberg School of Public Health (JHSPH). His research interests include exploring approaches to host directed adjuvant therapies in tuberculosis (TB) and studying the impact of TB and HIV on lung health of populations. Akshay is leading an Indo-US collaborative study aimed at exploring the impact of TB disease; alone and in combination with smoking, air pollution, HIV and diabetes mellitus...

Sangita Shelke, MD

BJGMC-JHU Fogarty HIV-TB Program Trainee
Pune, India
Dr. Sangita Shelke
Indeed TB is a social disease with so many social problems especially the women suffering from TB/HIV undergoes a pathetic life situation. Women are silent suffers, of both HIV and TB in male dominated society of India. My ultimate desire is if I can make a difference in the lives of these silent suffers.

Jessica Elf, MPH, PhD

Post Doctoral Fellow
Jessica Elf, MPH, PhD
Jessica Elf, MPH, PhD, is a post doctoral fellow in the Department of International Health at the Johns Hopkins School of Public Health. Her primary research focus has been on the epidemiology and health impacts of tobacco use and exposure to indoor air pollution from the combustion of biomass fuels. She is a former Fogarty Fellow who lived and worked in Pune, India conducting research for her thesis project, which investigated the association between indoor air pollution and tuberculosis. She completed her undergraduate education in nutrition at the University of Florida and received an MPH...

Dr. Smita Deshpande

BJGMC-JHU Fogarty HIV-TB Program Trainee
My research interests have been: Rapid diagnostic methods for Acute pyogenic meningitis, Diagnosis of enteric fever , Role of Methicillin resistance Staph aureus in infections, Molecular diagnosis of Leptospirosis, Rapid diagnosis of MDR-TB by REMA ( Resasurine Micro titre Plate Assay)and by Line Probe Assay.

Jeff Tornheim, MD, MPH

Assistant Professor
Jeff Tornheim, MD, MPH
Jeff Tornheim, MD, MPH, is Assistant Professor in the Division of Infectious Diseases here at Johns Hopkins University School of Medicine. His research explores the application of new diagnostic technologies to improved health outcomes in the treatment of drug resistant tuberculosis among both adult and pediatric patients in India. Dr. Tornheim recently completed his infectious diseases fellowship at Johns Hopkins, during which he worked with Drs. Amita Gupta, Vidya Mave, Bob Bollinger of Johns Hopkins, and with Dr. Zarir Udwadia at the Hinduja Hospital in Mumbai. His interest in clinical...

Dr. Chhaya Valvi

BJGMC-JHU Fogarty HIV-TB Program Trainee
Pune, India
Dr. Chhaya Valvi
Dr. Chhaya Valvi has completed her undergraduate and postgraduate medical education from the premier institute of Seth G.S. Medical College, Mumbai, India. She was awarded the prestigious Dr. Palekar prize as she ranked first among the candidates for M.D. exam.

Matt Robinson, MD

Infectious Disease Fellow
Baltimore, Maryland
Matthew Robinson, MD, is a clinical fellow in the Division of Infectious Diseases at Johns Hopkins University School of Medicine. His research interests include evaluating the etiology of febrile illness in resource limited settings using conventional and novel diagnostic techniques. Matt is working with Dr. Gupta and Dr. Mave to assess the etiology of febrile illness in patients presenting to a hospital in Pune, India. After completing his undergraduate and medical training at Northwestern University, he completed internal medicine residency at New York University. During medical school, he...

Dr. Vasudha Belgaumkar

BJGMC-JHU Fogarty HIV-TB Program Trainee
Pune, India
Dr. Vasudha Belgaumkar
Dr.Vasudha has completed her undergraduate medical education from S.B.H. Government Medical College, Dhule,Maharashtra .A meritorious student throughout, she topped her first and final year University examinations. She is presently working as Associate Professor of Dermatology at B.J. Government Medical College, Pune. Having completed her post-graduation in Dermatology, Venereology (including HIV) and Leprology from this premier institute, she has acquired clinical skills as well as an affinity for research.

Matthew Murrill

Baltimore, Maryland
Matthew Murrill
Matthew Murrill is an MD-PhD student in the Department of Epidemiology at the Johns Hopkins Bloomberg School of Public Health. In 2016, he was named an IDSA Education and Research Foundation Medical Scholar. After completing undergraduate studies in chemistry at Maryville College, he moved to Kolkata, India, as a Fulbright-Nehru fellow to research the sources and health effects of groundwater arsenic contamination in Eastern India with the School of Environmental Studies - Jadavpur University. He then worked for Calcutta Kids, a non-governmental organization, to establish a childhood diarrhea...

Rahul Lokhande, MD

BJGMC-JHU Fogarty HIV-TB Program Trainee
Pune, India
Dr. Rahul Lokhande
He is Unit In charge at B J Government Medical college and Sassoon Hospital Pune . He has special Interest in Bronchoscopy and Respiratory Intensive Care Unit of Sassoon Hospital.

Nicky Mehtani

Baltimore, Maryland
Nicky Mehtani
Dr. Mehtani is a second year internal medicine resident at Johns Hopkins Hospital. After studying Global Health Technologies as an undergraduate at Rice University, she pursued a medical degree at Johns Hopkins, where she also earned her MPH at the Bloomberg School of Public Health. As an MPH and medical student, she worked with Dr. Kathleen Page in analyzing Baltimore City STI surveillance data to help understand the initial effects of the Affordable Care Act on the demand for publicly-funded STD Clinics, and she continued to work on a three-year follow-up study of this issue as a medicine...

Dr. Shilpa Naik

BJGMC-JHU Fogarty HIV-TB Program Trainee
Pune, India
Dr. Shilpa Naik
I am working as an Associate Professor & Unit Incharge since 2009 in the Department of Obstetrics & Gynecology at B.J.Govt Medical College & Sassoon General Hospitals Pune. I have been managing High Risk Obstetrics and has keen interest in Critical Care Obstetrics.

Shivani Mehta

Baltimore, Maryland
Shivani Mehta is a BS/BA candidate (2018) in public health at the Johns Hopkins Krieger School of Arts and Sciences, who is working with Drs. Rupak Shivakoti and Mallika Alexander on Maternal Inflammation, Diet and Gut Microbiome in HIV: Impact on Infant Outcomes. Ms. Mehta spent June and July 2016 at BJGMC in Pune, India, working under Dr. Alexander. Awards 2016 Global Health Established Field Placement Grant 2016 Johns Hopkins Provost Undergradulate Research Award for 2016-17 From Ms. Mehta's Field Report: This week, as the patients come in, I have been sitting with the counselors and...

Abhilash Suresh

Baltimore, Maryland
Abhilash Suresh is a BS candidate in biomedical engineering at Johns Hopkins Whiting School of Engineering (2018), who worked with Drs. Akshay Gupte and Shri Vijay Bala Yogendra Shivakumar on the C-TRIUMPH substudy on Residual Respiratory Impairment Following Pulmonary Tuberculosis. During May and June 2016 he conducted a field placement in Chennai, India, at the National Institute for Research in Tuberculosis where he worked under Dr. Shivakumar. Awards 2016 Global Health Established Field Placement Grant From Mr. Suresh's Field Report: This placement opened my eyes to how healthcare works...

Saraniya Tharmarajah

Saraniya Tharmarajah is a public health studies student at the Johns Hopkins Krieger School of Arts and Sciences (2017). During June-July 2015, she conducted a field study placement at the National Institute of Research in Tuberculosis in Chennai, India, where she worked on the C-TRIUMPH lung health substudy. Ms. Tharmarajah is a 2015 recipient of the Global Health Established Field Placement Grant.

Prarthana Vasudevan

Baltimore, Maryland
Prar Vasudevan is an international health graduate student at the Johns Hopkins School of Public Health. In Autumn 2015, she conducted a field placement in Pune, India, at BJGMC under Dr. Vidya Mave, where she worked on the study titled Maternal Inflammation, Diet and Gut Microbiome in HIV: Impact on Infant Outcomes. She is a 2015 recipient of the Global Health Established Field Placement Grant. From Prar Vasudevan's Field Report: At BJMC, I had the opportunity to make rounds in the hospital’s ART Clinic, Labor & Delivery wards, and children’s wards. I was immediately struck by the fact...

Jeff Tornheim, MD, MPH

Infectious Disease Fellow
Baltimore, Maryland
Jeff Tornheim, MD, MPH, is a clinical fellow in the Division of Infectious Disease here at Johns Hopkins University School of Medicine. After completing undergraduate studies in International Development and Economics at Brandeis University he moved to East Africa where he engaged in health system strengthening for returning refugees to South Sudan and worked with the Centers for Disease Control and Prevention (CDC) on the epidemiology of pneumonia and diarrhea in Western Kenya. He completed a joint MD/MPH at Mount Sinai School of Medicine, with his thesis evaluating the impact of water...

Aarti Avinash Kinikar, MD

BJGMC-JHU Fogarty HIV-TB Program Trainee
Pune, India
Education : MBBS (1984); DCH (1988); MD-Paediatrics (1988), DNB-Paediatrics (2003); MRCP-UK (1995). Medical Education- Grant Medical College – Mumbai University, India.

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Johns Hopkins University Task Force on Women's Academic Careers in Medicine

Post Date: 
2015-01-01
Natasha Chida: Member, 2013-Present Amita Gupta: Member, 2015-Present

Regional Prospective Observational Research for Tuberculosis (RePORT) India Executive Committee

Post Date: 
2014-01-01
US Chair, 2016-Present US Co-chair, 2014-2016

IMPAACT Clinical Trial Network Tuberculosis Scientific Committee

Post Date: 
2012-01-01
Vice Chair Elect, 2012-Present

2012 43rd Union World Conference on Lung Health Conference Committee

Post Date: 
2012-01-01
Abstract Reviewer, 2012

ACTG Clincial Trial Group, Women's Health Inter-Network Scientific Committee

Post Date: 
2011-01-01
Tuberculosis Working Group Member, 2011-2013

ACTG Tuberculosis Transformative Science Group

Post Date: 
2011-01-01
Amita Gupta: Elected Member, 2011-2013 Vidya Mave: Elected Member, 2016-2017

International Union Against Tuberculosis and Lung Disease

Post Date: 
2009-01-01
Amita Gupta, Member, 2009-Present. Maunank Shah, Member, 2009–Present.

National Institutes of Health/National Institute of Child Health and Human Development Study Section

Post Date: 
2008-01-01
Invited RO1 Grant Reviewer, 2008 ZHD1 DSR-K (07) 1- Diagnostic and pharmacokinetic research in pediatric HIV/TB and effects of co-infection on the central nervous system

Johns Hopkins Center for Global Health Grant Review Committee

Post Date: 
2008-01-01
Amita Gupta: Grants Reviewer, 2010 Amita Gupta: Faculty Grants Reviewer, 2008

American Academy of HIV Medicine

Post Date: 
2008-01-01
Amita Gupta: Member, 2008-Present

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Isoniazid preventive therapy: do the risks outweigh the benefits in pregnant women with HIV?

Post Date: 
2018-03-13
Source: 
aidsmap
. . . Isoniazid preventive therapy (IPT) during and after pregnancy in women living with HIV on antiretroviral therapy (ART) in tuberculosis (TB) endemic areas in Africa, Asia and Haiti resulted in serious adverse events quite possibly attributable to isoniazid with no significant reduction in TB...

Adverse pregnancy outcomes with isoniazid preventive therapy in HIV

Post Date: 
2018-03-09
Source: 
Infectious Disease Advisor
. . . The safety of IPT in pregnant women with HIV is unknown, especially with regard to its combination with highly active antiretroviral therapy (ART). Amita Gupta, MD, deputy director of the Johns Hopkins University Center for Clinical Global Health Education at the Johns Hopkins University...

No difference in safety for HIV+ pregnant women deferring TB Tx

Post Date: 
2018-03-09
Source: 
MedPage Today
MedPage Today
First randomized clinical trail of IPT in pregnant and postpartum women may suggest need for WHO guideline change.

Preventive TB therapy during pregnancy causes excessive adverse events

Post Date: 
2018-03-08
Source: 
Healio Infectious Disease News
. . . “Identifying ways to prevent TB during pregnancy and the postpartum period is a really important way to address maternal and infant health for a globally important disease such as tuberculosis,” Amita Gupta, MD, MHS, associate professor of medicine and international health and deputy director...

Study Results for IMPAACT P1078 Presented at CROI 2018

Post Date: 
2018-03-07
Source: 
IMPAACT Network News
IMPAACT Network News: Dr. Amita Gupta presented findings at CROI 2018.

One-Month Tuberculosis Prophylaxis as Effective as Nine-Month Regimen for People Living with HIV

Post Date: 
2018-03-05
NIH Logo
The Indo-JHU Clinical Research Partnership participated in this important study that could change TB prevention for people living with HIV.

Tip Sheet: Johns Hopkins Researchers Present at Annual CROI Meeting

Post Date: 
2018-03-01
Newswise — Amita Gupta, M.D., deputy director of the Johns Hopkins University Center for Clinical Global Health Education at the Johns Hopkins University School of Medicine, will present a multicounty study of preventive treatment for tuberculosis (TB) in HIV-infected pregnant and postpartum women—...

2017 Year in Review

Post Date: 
2018-02-19
What a year! Our 2017 Year In Review outlines the most ambitious 365 days we’ve had to date.

Uniting for a Healthier India

Post Date: 
2018-02-14
Uniting India slide
"The Indo-US clinical research & education partnership started with a single NIH grant to study maternal-infant HIV transmission." Now with 76 studies underway, this short film chronicles the history & impact of our work in India.

Celebrating Johns Hopkins Medicine's impact in India

Post Date: 
2017-12-13
Source: 
The Campaign for Johns Hopkins Medicine
In 4 years, the CCGHE has tripled its capacity for conducting research on grave health threats, thanks to strong philanthropic support.

Transforming India from TB Hot Zone to TB Hot Shot

Post Date: 
2017-12-09
Source: 
Indiaspora
Dr. Amita Gupta's invited commentary: Can Indian transform its role in the global TB epidemic?

CCGHE Joins 12-Country UNITAID Effort to Control TB

Post Date: 
2017-11-08
Shorter course to prevent progression of latent TB to active disease is the aim of the effort.

Reduced Level of Disease Possible in India by the Centennial

Post Date: 
2017-08-22
Source: 
India Abroad
India ranks highest in global disease burden. Dr. Amita Gupta weighs in on how to reverse that.

Indo-Hopkins Partnership Seeks Causes of Sepsis in the NICU

Post Date: 
2017-08-10
Sepsis among newborns in the neonatal intensive care unit (NICU) is a big problem in India, and a complex one to untangle.

How can we encourage female leaders in global health?

Post Date: 
2017-08-09
Source: 
Global Health Matters
Fogarty Director Dr. Roger Glass asks why so few women are leading global health centers at med schools or filling other leadership roles.

Health on the Go: Mobile Clinic Delivers TB Services at Point of Need

Post Date: 
2017-03-24
Thanks to Raj and Bharti Shah, CTIS, & the NB Shah Charitable Trust, we are able to reach more people in Maharashtra who need care

CROI 2017 Highlighted ACTG Network Presentations

Post Date: 
2017-02-28
Source: 
ACTG Newsletter
A5274: Impact of INH adherence on TB incidence and mortality by week 96 in REMEMBER Trial Amita Gupta, MD, MHS, Baltimore-Washington-India Clinical Trials Unit, co-PI and Investigator, Johns Hopkins University Clinical Research Site The A5274/REMEMBER trial team previously reported that among those...

2017 Directors' Statement

Post Date: 
2017-01-31
A New Decade of Global Health Impact The CCGHE recently marked its 10-year anniversary, and it’s an occasion that affords an opportunity to reflect on the progress we’ve made so far, and envision what lies ahead. We are encouraged by the changes we’ve seen in health outcomes for people living with...

Amita Gupta Appointed US Chair for India TB Research Consortium

Post Date: 
2016-05-11
“After more than 40 years of little discovery, interest, or funding for TB research, we are at a nexus of advancement."

Proactively treating HIV patients at risk for tuberculosis with multi-drug TB regimens doesn't save more lives

Post Date: 
2016-03-20
Source: 
Health Canal
The number one killer of HIV patients in resource-limited areas, including parts of Africa and India, is tuberculosis (TB), underscoring the need for optimal treatments and effective strategies to address this deadly co-infection. But TB is harder to detect in HIV-infected patients and diagnostic...

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