Amita Gupta, MD, MHS

Role: 
Director
Associate Professor of Medicine and Public Health

Dr. Gupta is Deputy Director of the Johns Hopkins (JH) Center for Clinical Global Health Education (CCGHE), and Associate Professor of Infectious Diseases at the JH School of Medicine, with a joint appointment in International Health at the JH Bloomberg School of Public Health.

Board certified by the American Board of Internal Medicine in infectious diseases, Dr. Gupta specializes in international public health, clinical research, and education in infectious diseases, HIV/AIDS, and tuberculosis (TB). Since 2002, her work has been focused primarily on India, where she leads several Indo-JHU research collaborations. She serves in leadership positions for the RePORT consortium for TB research, funded by the US National Institutes of Health (NIH) and the government of India, including on the RePORT International Executive Committee, as US Chair of RePORT India, and as PI of the multi-site C-TRIUMPH research consortium.

Dr. Gupta is Co-principal Investigator of the NIH-funded Baltimore-Washington-India HIV and Infectious Diseases Clinical Trials Unit (BWI-CTU), and she is an active clinical investigator in multi-country HIV/TB trials conducted by the AIDS Clinical Trials Group (ACTG) and the International Maternal Pediatric Adolescent AIDS Trials Network (IMPAACT). Additionally, she has been awarded research grants from the NIH, CDC, and several philanthropic foundations to investigate TB in children and pregnant women, malnutrition, infection and inflammation, HIV treatment outcomes, and antibiotic resistance. ​Learn about CCGHE India Research Partnerships

Dr. Gupta is an author of more than 100 peer-reviewed research publications and 7 book chapters on prevention and treatment of HIV, TB, and other infectious diseases, predominantly in low- and middle-income settings. She has also mentored more than 30 junior scientists in India and the US to run research studies and submit their own scientific findings to peer-reviewed publications.

From 2000–2002, Dr. Gupta worked in the US Public Health Service for the Centers for Disease Control and Prevention (CDC), where she was engaged in global public health projects in the US, Guatemala, Vietnam, and Micronesia.

Dr. Gupta received an undergraduate degree from MIT, a Doctor of Medicine from Harvard Medical School, and a Master of Health Sciences in clinical investigation from JH Bloomberg School of Public Health. She completed her internal medicine training at San Francisco General Hospital-University of California, San Francisco, followed by a post-doctoral fellowships with the Epidemic Intelligence Service at the US Centers for Disease Control and Prevention (Foodborne and Diarrheal Diseases) and at the JHU School of Medicine (Infectious Diseases).

Assessing Psychological Distress among Tuberculosis Patients and Their Household Members

Post Date: 
2018-07-17
   |   
Clinical Sites: 
   |   
Countries: 
By assessing psychological distress, Indo-JHU researchers hope to better understand the correlation between depression and TB severity.

Evaluating the Source of Neonatal Bloodstream Infections due to Classically Hospital Acquired Pathogens in the Neonatal Intensive Care Unit in Pune, India

Post Date: 
2018-07-12
   |   
Clinical Sites: 
   |   
Countries: 
This study is part of CDC's Safe healthcare, Epidemiology, and Prevention Research Development (SHEPheRD) Domain 7: International HAI and Other Adverse Healthcare Event Prevention. The PIs for this study are Dr. Julia Johnson of Johns Hopkins and Dr. Shilpa Naik of BJGMC. CoPIs are Dr. Aarti...

Assessing the Feasibility and Acceptability of a Computer-based Avatar-delivered Alcohol Reduction Intervention

Post Date: 
2018-07-05
   |   
Clinical Sites: 
   |   
Countries: 
Study is assessing whether computer-delivered alcohol screening and intervention helps overcome barriers to treatment in India.

Molecular Signatures of Tuberculosis-Diabetes Interaction: Transcriptomics Study

Post Date: 
2018-06-15
   |   
Clinical Sites: 
   |   
Countries: 
Type 2 diabetes is an acquired host factor that increases the risk for and severity of pulmonary tuberculosis. A report published in 2007 estimated that, in India, diabetes accounted for 14.8% (range 7.1% to 23.8%) of pulmonary tuberculosis and 20.2% (8.3% to 41.9%) of smear-positive cases...

Molecular Signatures of Tuberculosis-Diabetes Interaction: Metabolomics Study

Post Date: 
2018-06-15
   |   
Clinical Sites: 
   |   
Countries: 
Type 2 diabetes mellitus (DM) is an acquired host factor that increases the risk for and severity of pulmonary tuberculosis (PTB). A report published in 2007 estimated that, in India, DM accounted for 14.8% (range 7.1% to 23.8%) of PTB and 20.2% (8.3% to 41.9%) of smear-positive PTB. Emerging data...

Gut Microbiota of HIV Infected Pregnant Women

Post Date: 
2018-06-14
   |   
Clinical Sites: 
   |   
Countries: 
Birth Outcomes in HIV Both antiretroviral-therapy (ART)-naïve and ART-experienced HIV-infected pregnant women have higher incidences of pre-term birth (PTB) compared to HIV-uninfected women. For example, the global prevalence of PTB is around 8%, while the rates in in HIV-infected populations are...

Assessing Tuberculosis Transmission Dynamics, Drug Resistance and Recurrence Using Whole Genome Sequencing in Pune, India

Post Date: 
2018-06-12
   |   
Countries: 
Indo-JHU researchers are using combined geospatial and genotyping methods to describe TB transmission dynamics in a hyperlocal region of Pune City in Western India.

Optimal Approach for TB Screening among HIV Infected Indian Children

Post Date: 
2018-06-11
   |   
Clinical Sites: 
   |   
Countries: 
Determining TB status (ie, uninfected, latent, and active TB disease) is more difficult among children, particularly HIV-infected children. Diagnosis of TB disease is more difficult among HIV infected children because the signs and symptoms of the disease—such as weight loss, cough, and mild fever—...

Implementing the Comprehensive Unit-based Safety Program to Reduce Healthcare-Associated Sepsis in the Neonatal Intensive Care Unit in Pune, India

Post Date: 
2018-04-19
   |   
Clinical Sites: 
   |   
Countries: 
This study is part of CDC's Safe healthcare, Epidemiology, and Prevention Research Development (SHEPheRD) Domain 7: International HAI and Other Adverse Healthcare Event Prevention. Dr. Aaron Milstone is the PI, and Dr. Amita Gupta and Yuka Manabe are Co-PIs. the Study Investigator is Dr. Julia...

Predictors of Resistance Emergence Evaluation in Multidrug Resistant-Tuberculosis Patients on Treatment (PREEMPT Pilot Study)

Post Date: 
2018-03-20
   |   
Clinical Sites: 
   |   
Countries: 
Indo-JHU Clinical Resarch Partnership is participating with Brazilian colleagues in a 3-year effort led by Boston University to identify what contributes to TB drug resistance.

A Multicenter Phase II/II Double-Blind, Randomized, Placebo Controlled Study to Evaluate the Efficacy and Safety of VPM1002 in the Prevention of Tuberculosis (TB) Recurrence in Pulmonary TB Patients After Successful TB Treatment in India

Post Date: 
2018-01-23
   |   
Clinical Sites: 
   |   
Countries: 
Dr. Vidya Mave is leading this clinical trial evaluating the safety and efficacy of a new recombinant BCG vaccine.

Perceptions of HCWs on Barriers and Opportunities to Airborne Infection Control Guideline Implementation

Post Date: 
2017-12-07
   |   
Clinical Sites: 
   |   
Countries: 
Led by Dr. Nishi Suryavanshi, this qualitative, cross-sectional study is assessing healthcare worker (HCW) perceptions about barriers and facilitators to the uptake of airborne infection control (AIC) guidelines. Further, the study is assessing the potential barriers and opportunities to develop...

The Role of GeneXpert in Bacterial Diagnosis of Spinal Tuberculosis

Post Date: 
2017-10-26
   |   
Clinical Sites: 
   |   
Countries: 
India has the maximum burden of tuberculosis (TB) in the world. In 2014, there were an estimated 9.6 million incident cases of TB (range, 9.1 million–10.0 million) globally, equivalent to 133 cases per 100000 population. Most of the estimated number of cases in 2014 occurred in Asia (58%) and the...

TREAT Asia: Substudy on Assessment of Cardiovascular Health Knowledge, Preventive Practices and Cardio-protective Behavior among HIV-infected Individuals in Pune, India

Post Date: 
2017-10-12
   |   
Clinical Sites: 
   |   
Countries: 
Cardiovascular Diseases (CVD) have become one of the leading causes of death among PLWH (People Living with HIV) across the globe. The burden that CVD will pose in the imminent future for the 2.1 million HIV-infected individuals in India is currently unclear. However given that Indians have a...

Impact of Diabetes on TB Treatment Outcomes: Nested Study: Lipid Mediators of Inflammation in TB and TB-Diabetes

Post Date: 
2017-10-02
   |   
Clinical Sites: 
   |   
Countries: 
Studies have shown that individuals with Tuberculosis (TB) and diabetes (TB-DM) have a distinct immune profile compared to individuals with TB alone. Individuals with TB-DM have higher inflammation, a higher bacillary load, increased Th1 immune responses and a defective neutrophil and macrophage...

RePORT: C-TRIUMPH: Nested Study on Targeting Mycobacterium Tuberculosis Persisters by Enhancing Stringent Response-specific Cellular Immunity

Post Date: 
2017-09-11
   |   
Clinical Sites: 
   |   
Countries: 
C-TRIUMPH nested study begins to see if stringent response antigen is enhanced while treating drug-susceptible TB using the first-line anti-TB regimen.

Zika Surveillance among Antenatal Clinic Outpatients in BJ Government Medical College and Sassoon General Hospitals, Pune, India

Post Date: 
2017-08-31
   |   
Clinical Sites: 
   |   
Countries: 
CCGHE is keeping an eye on Zika among pregnant women, which is transmitted by mosquitoes & can cause devastating birth defects.

The Role of Innate Immunity in the Acquisition of Sterile Protection against TB Infection

Post Date: 
2017-08-25
   |   
Clinical Sites: 
   |   
Countries: 
Tuberculosis (TB) is a major global health problem. Vaccines are the most powerful instruments for limiting the morbidity and mortality of infectious diseases, so the development of highly protective TB vaccines is one of the highest priorities in public health. Bacille de Calmette et Guérin (BCG...

Validation of Transcriptional Signature to Predict Active TB Disease among Advanced HIV Patients

Post Date: 
2017-08-15
   |   
Clinical Sites: 
   |   
Countries: 
There have been tremendous advances in the diagnosis of patients with tuberculosis (TB) based on nucleic acid amplification of bacteria in the sputum. The GenXpert MTB/RIF provides results in 2 hours. However, in HIV-infected sputum smear is often negative for AFB and the sensitivity of GenXpert...

Antimicrobial Use and Diagnosis among Hospitalized Febrile Patients in Pune, India

Post Date: 
2017-08-07
   |   
Clinical Sites: 
   |   
Countries: 
Antimicrobial resistance, a leading threat to human health, is enabled by unnecessary antibiotic use. Strategies to reduce unnecessary antibiotic use in India, the world’s largest antibiotic consumer, are urgently needed. Although most patients hospitalized in India with acute febrile illness...

Pages

Report of the Technical Consultation on Advances in Clinical Trial Design for Development of New TB Treatments

Post Date: 
2018-09-17
Publication: 
WHO Task Force on Introduction of New TB Drugs and Treatment Regimens
Dr. Amita Gupta was a member of this TB technical consultation, convened in March 2018 in Switzerland.

The association of household fine particulate matter and kerosene with tuberculosis in women and children in Pune, India

Post Date: 
2018-09-07
   |   
Clinical Sites: 
   |   
Countries: 
Publication: 
Occupational and Environmental Medicine
Use of kerosene cooking fuel is positively associated with TB in women and children in our analysis using reported sources of exposure.

Challenges and opportunities for outreach workers in the Prevention of Mother to Child Transmission of HIV (PMTCT) program in India

Post Date: 
2018-09-04
   |   
Countries: 
Publication: 
PLoS One
The Prevention of Mother-to-Child Transmission of HIV (PMTCT) program in India is one of the largest in the world. It uses outreach workers (ORWs) to facilitate patient uptake of services, however, the challenges faced by the ORWs, and their views about the effectiveness of this program are unknown.

Resource utilization for multidrug-resistant tuberculosis household contact investigations (A5300/I2003)

Post Date: 
2018-09-01
   |   
Clinical Sites: 
Publication: 
International Journal of Tuberculosis and Lung Disease
Current guidelines recommend evaluation of the household contacts of individuals with multidrug-resistant tuberculosis; however, implementation of this policy is challenging.

The effect of diabetes mellitus on the pharmacokinetics and pharmacodynamics of tuberculosis treatment

Post Date: 
2018-08-20
   |   
Clinical Sites: 
   |   
Countries: 
Publication: 
Antimicrobial Agents and Chemotherapy
DM and higher HbA1c increased the risk of not achieving therapeutic targets for pyrazinamide, but higher pyrazinamide concentrations were asociated with worse microbiologic and clinical outcomes

Tuberculin skin test and QuantiFERON-Gold In Tube assay for diagnosis of latent TB infection among household contacts of pulmonary TB patients in high TB burden setting.

Post Date: 
2018-08-01
   |   
Countries: 
Publication: 
PLoS One
World Health Organization (WHO) recommends systematic screening of high-risk populations, including household contacts (HHCs) of adult pulmonary tuberculosis (TB) patients, as a key strategy for elimination of TB. QuantiFERON-TB Gold In-Tube (QFT-GIT) assay and tuberculin skin test (TST) are two commonly used tools for the detection of latent tuberculosis infection (LTBI) but may yield differential results, affecting eligibility for TB preventive therapy.

Trends in HbA1c levels and implications for diabetes screening in tuberculosis cases undergoing treatment in India

Post Date: 
2018-07-01
   |   
Clinical Sites: 
   |   
Countries: 
Publication: 
International Journal of Tuberculosis and Lung Disease
SETTING: The optimal timing of screening for diabetes mellitus (DM) among tuberculosis (TB) cases is unclear due to the possibility of stress hyperglycemia. DESIGN: We evaluated adult (18 years) pulmonary TB cases at treatment initiation as well as at 3 months, 6 months and 12 months. DM was...

Internal medicine residents' knowledge and practice of pulmonary tuberculosis diagnosis

Post Date: 
2018-06-27
   |   
Countries: 
Publication: 
Open Forum Infectious Diseases
BACKGROUND: Internal medicine physicians are often the first providers to encounter patients with a new diagnosis of tuberculosis. Given the public health risks of missed tuberculosis cases, assessing internal medicine residents' ability to diagnose tuberculosis is important. METHODS: Internal...

Loss to follow‐up and mortality among HIV‐infected adolescents receiving antiretroviral therapy in Pune, India

Post Date: 
2018-06-25
   |   
Clinical Sites: 
   |   
Countries: 
Publication: 
HIV Medicine
Over 6 years, one-third of HIV+ adolescents in this study discontinued medical treatment, indicating a critical need for retention counselling and closer clinical monitoring.

Developing an assessment framework for essential internal medicine subspecialty topics

Post Date: 
2018-06-15
   |   
Countries: 
Publication: 
Journal of Graduate Medical Education
Our assessment framework revealed knowledge and practice gaps in tuberculosis diagnosis among internal medicine residents.

Effect of baseline micronutrient and inflammation status on CD4 recovery post-cART initiation in the multinational PEARLS trial.

Post Date: 
2018-05-29
   |   
Countries: 
Publication: 
Clinical Nutrition
Nutritional deficiency and inflammation may impact CD4+ T cell recovery during combination antiretroviral therapy (cART), particularly in resource-limited settings where malnutrition is prevalent. The aim of this study was to investigate the relationship of micronutrient and inflammation biomarkers to CD4 recovery after cART initiation.

Sources of household air pollution and their association with fine particulate matter in low-income urban homes in India

Post Date: 
2018-05-23
   |   
Clinical Sites: 
   |   
Countries: 
Publication: 
Journal of Exposure Science and Environmental Epidemiology
INTRODUCTION: Household air pollution (HAP) is poorly characterized in low-income urban Indian communities. MATERIALS AND METHODS: A questionnaire assessing sources of HAP and 24 h household concentrations of particulate matter less than 2.5 microns in diameter (PM 2.5 ) were collected in a sample...

Diabetes and pre-diabetes among household contacts of tuberculosis patients in India: is it time to screen them all?

Post Date: 
2018-05-22
   |   
Clinical Sites: 
   |   
Countries: 
Publication: 
The International Journal of Tuberculosis and Lung Disease
Authors find that screening contacts of TB patients for pre-DM/DM and linking them to care may mitigate the risk of developing tuberculosis and improve management of diabetes.

The global neurological burden of tuberculosis

Post Date: 
2018-05-18
Publication: 
Seminars in Neurology
Central nervous system (CNS) involvement of tuberculosis (TB) is the most severe manifestation of TB and accounts for approximately 5 to 10% of all extrapulmonary TB (EPTB) cases and approximately 1% of all TB cases. TB meningitis (TBM) is the most common form of CNS TB, though other forms occur,...

Addressing knowledge gaps and prevention for tuberculosis-infected Indian adults: a vital part of elimination

Post Date: 
2018-05-02
   |   
Clinical Sites: 
   |   
Countries: 
Publication: 
BMC Infectious Diseases
BMC Infectious Diseases : Our survey among TB patients' household contacts with evidence of recent exposure found that knowledge is poor and families are confused about disease transmission.

Hepatotoxicity during isoniazid preventive therapy and antiretroviral therapy in people living with HIV with severe immunosuppression: a secondary analysis of a multi-country open-label randomized controlled clinical trial

Post Date: 
2018-05-01
   |   
Publication: 
Journal of Acquired Immune Deficiency Syndromes
Hepatotoxicity associated with isoniazid preventive therapy (IPT) and antiretroviral therapy (ART) has not been well studied in severely immunosuppressed people with HIV. Our objective was to determine risk factors for hepatotoxicity in severely immunosuppressed individuals taking IPT and ART.

Vector-borne disease is a common cause of hospitalized febrile illness in India

Post Date: 
2018-03-26
   |   
Clinical Sites: 
Publication: 
American Journal of Tropical Medicine and Hygiene
Diagnostic strategies adapted for season and age may reduce diagnostic uncertainty and identify causative organisms in treatable, fatal causes of AFI.

Intestinal barrier dysfunction and microbial translocation in HIV-infected pregnant women is associated with preterm birth

Post Date: 
2018-03-24
   |   
Clinical Sites: 
   |   
Countries: 
Publication: 
Clinical Infectious Diseases
Our results show select immune markers can identify women at higher risk for PTB in HIV-1-infected populations and suggest modulating gut barrier integrity and microbial translocation may affect PTB.

Gender-based violence screening methods preferred by women visiting a public hospital in Pune, India

Post Date: 
2018-01-22
   |   
Clinical Sites: 
   |   
Countries: 
Publication: 
BMC Womens Health
BMC Womens Health : In our study, 23% of women reported experiencing gender based violence, and 90% reported they had never been asked about it in the healthcare setting.

Secondhand smoke exposure and validity of self-report in low-income women and children in India

Post Date: 
2018-01-10
   |   
Countries: 
Publication: 
Pediatrics
Pediatrics: Dr. Jessica Elf and colleagues evaluated the validity of standard self-reported measures for secondhand smoke (SHS) exposure among women and children in urban India.

Pages

Antibiotic Use and Drug-Resistant Late-Onset Infections Among Neonates Admitted to Neonatal Intensive Care Units in Pune, India

Post Date: 
2018-08-28
   |   
Countries: 
Presentation Location: 
Atlanta, GA
Event & Convener: 
2018 International Conference on Emerging Infectious Diseases
Poster presentation. Agarkhedkar S, Armstrong D, Bharadwaj R, Cox SR, Dohe V, Gupta A, Gupte N, Johnson J, Kadam A, Kinikar A, Malwade S, Manabe Y, Mave V, Milstone A, Parikh T, Rajput U, Randive B, Robinson M , Smith R, Suryavanshi N, Vaidya U, Westercamp M. Antibiotic Use and Drug-Resistant Late-...

High Prevalence of Dengue among Pregnant Women in India

Post Date: 
2018-08-27
   |   
Clinical Sites: 
   |   
Countries: 
Presentation Location: 
Atlanta, GA
Event & Convener: 
2018 International Conference on Emerging Infectious Diseases
Poster presentation. Alexander M, Naik S, Robinson M , Sapkal G, Deshpande P, Kulkarni V, Nimkar S, Sambarey P, Kinikar A, Mave V, Suryavanshi N, Gupte N, Bollinger R, Gupta A, Bharadwaj R, Mathad J. High Prevalence of Dengue among Pregnant Women in India. 2018 International Conference on Emerging...

Mobile Health and Behavioral PMTCT Intervention among Community Health Workers Improves Exclusive Breastfeeding and Early Infant Diagnosis in India: A Cluster Randomized Trial

Post Date: 
2018-07-24
   |   
Clinical Sites: 
   |   
Countries: 
Presentation Location: 
Amsterdam, The Netherlands
Event & Convener: 
AIDS 2018, International AIDS Society
Tablet-based HIV treatment resources & training community health workers to prevent mother-to-child transmission.

Opportunities, Challenges and Implications of m-Health Oral Cancer Screening for HIV-positive Individuals in India

Post Date: 
2018-07-23
   |   
Clinical Sites: 
   |   
Countries: 
Presentation Location: 
Amsterdam, The Netherlands
Event & Convener: 
AIDS 2018, International AIDS Society
Joshi S, Chandanwale A, Sangle S, Marbaniang I , Khaire S, Thakur R, Gupta A, Chigurupati R, Mave V. Opportunities, Challenges and Implications of m-Health Oral Cancer Screening for HIV-positive Individuals in India. AIDS 2018. Amsterdam, The Netherlands. July 23-27, 2018.

Health-related Quality of Life in the A5274 Trial of TB Therapy in Advanced HIV

Post Date: 
2018-07-22
   |   
Clinical Sites: 
Presentation Location: 
Amsterdam, The Netherlands
Event & Convener: 
TB 2018
Lando R, Sun X, Miyahara S, Hosseinpour MC, Bisson GP, Kumwenda J, Gupta A, Nyirenda M, Katendey K, Torres TS, Suryavanshi N, Beulah F, Opollo V, Shah NS on behalf of the A5274 study team. Health-related Quality of Life in the A5274 Trial of TB Therapy in Advanced HIV. TB 2018, Amsterdam, The...

Randomized Trial of Safety of Isoniazid Preventive Therapy During or After Pregnancy

Post Date: 
2018-03-07
   |   
Clinical Sites: 
Presentation Location: 
Boston, MA
Event & Convener: 
CROI 2018
Oral Presentation. Gupta A, Montepiedra G, Aaron L, Theron G, McCarthy K, Onyango-Makumbi C, Chipate T, Masheto G, Shin K, Zimmer B, Sterling TR, Chakhtoura N, Jean-Philippe P, Weinberg A for the IMPAACT P1078/TB APPRISE Study Team.

GLP-1 and C-Peptide are Associated with Insulin Resistance among PLWH in India

Post Date: 
2018-03-07
   |   
Clinical Sites: 
   |   
Countries: 
Presentation Location: 
Boston, MA
Event & Convener: 
CROI 2018
Poster Presentation. Marbaniang I, Sangle S, Kadam D, Kulkarni V, Shere D, Gupte N, Gupta A, Mave V

Inflammation in HIV-Infected Pregnant Women is Associated with Pre-term Birth

Post Date: 
2018-03-07
   |   
Clinical Sites: 
   |   
Countries: 
Presentation Location: 
Boston, MA
Event & Convener: 
CROI 2018
Poster Presentation. Shivakoti R, Gupte N, Kumar NP, Kulkarni V, Balasubramanian U, Bhosale R, Sambarey P, Kinikar A, Bharadwaj R, Patil S, Inamdar S, Suryavanshi N, Babu S, Bollinger R, Gupta A

One Month of Rifapentine/Isoniazid to Prevent TB In People With HIV: Brief-TB/A5279

Post Date: 
2018-03-05
   |   
Clinical Sites: 
   |   
Countries: 
Presentation Location: 
Boston, MA
Event & Convener: 
CROI 2018
Abstract Presentation. Swindells S, Ramchandani R, Gupta A, Benson CA, Leon-Cruz JT, Omoz-Oarhe A, Juste MAJ, Lama JR, Valencia JA, Badal-Faesen S, Moran LE, Fletcher CV, Nuermberger E, Chaisson RE.

Infection Free “Resistors” among Household Contacts of Culture-Confirmed Adult Pulmonary TB Cases

Post Date: 
2018-02-21
   |   
Clinical Sites: 
   |   
Countries: 
Presentation Location: 
New Delhi, India
Event & Convener: 
5th Global Forum on TB Vaccines
Presentation. Mave V , Chandrasekaran P, Paradkar M, Gupte A, Pradhan N, Kannan GN, Shivakumar SVBY, Kulkarni V, Dhanasekaran K, Subramanyam B, Selvaraju S, Murali L, Bharadwaj R, Gaikwad S, Meshram S, Kinikar A, Hanna LE, Swaminathan S, Gupte N, Gupta A.

TB Infection Among Household Contacts: Preventive Therapy for All?

Post Date: 
2018-02-21
   |   
Clinical Sites: 
   |   
Countries: 
Presentation Location: 
New Delhi, India
Event & Convener: 
5th Global Forum on TB Vaccines
Presentation. Dolla CK, Paradkar M, Gupte A, Thiruvenkadam K, Gupte N, Kulkarni A, Balasubranian U, Hanna LE, Dhanasekaran K, Bharadwaj R, Shivakumar SVBY, Gaikwad S, Meshram S, Kohli R, Lokhande R, Thomas B, Kinikar A, Swaminathan S, Mave V, Gupta A, Chandrasekaran P

Incidence of Mycobacterium tuberculosis Infection among Household Contacts of Adult Pulmonary Tuberculosis Cases in India

Post Date: 
2018-02-20
   |   
Clinical Sites: 
   |   
Countries: 
Presentation Location: 
New Delhi, India
Event & Convener: 
5th Global Forum on TB Vaccines
Presentation. Selvaraju S, Thiruvenkadam K, Paradkar M , Marinaik SB, Bharadwaj R, Rajagopalan S, Gaikwad S, Pattabiraman S, Kinikar A, Sivaramakrishnan GN, Meshram S, Hanna LE, Lokhande R, Dhanasekaran K, Gupte A, John S, Gupte N, Thomas B, Kukarni V, Ayyanu S, Kohli R, Shivakumar SVBY,...

The Effect of HIV on the Immune Response to Myobacterium tuberculosis in Pregnant Women from Pune, India.

Post Date: 
2018-02-15
Presentation Location: 
New Delhi, India
Event & Convener: 
RePORT India Annual Meeting
Mathad J, Alexander M, Bhosale R, Naik S, Suryavanshi N, Mave V, Deshpande P, Balasubramanian U, Kulkarni V, Kumar P, Babu S, Gupte N, Nevrekar N, Patil S, Chandanwale A, Gupta A.

Incidence of Mycobacterium tuberculosis Infection among Household Contacts of Adult Pulmonary Tuberculosis Cases in India

Post Date: 
2018-02-15
   |   
Countries: 
Presentation Location: 
New Delhi, India
Event & Convener: 
CTRIUMPh Study Team, RePORT India Annual Meeting
Paradkar M, Dhanasekaran K, Kinikar A, Kulkarni R, Bharadwaj R, Gaikwad S, Lokhande R, Meshram S, Dolla CK, Selvaraju S, Murali L, Thiruvengadam K, Jain D, Rajagopal S, Kulkarni V, Pradhan N, John S, Kohli R, Nayagam R, Shivakumar SVBY, Suryavanshi N, Cox S, Gupte A, Chandrasekaran P, Mave V, Gupta...

Poor Understanding of TB Infection among At-risk Tuberculin Skin-test Positive Household Contacts of Pulmonary TB Cases in Pune, India

Post Date: 
2018-02-15
   |   
Countries: 
Presentation Location: 
New Delhi, India.
Event & Convener: 
RePORT India Annual Meeting
Dhumal G, DeLuca A, Paradkar M, Suryavanshi N, Mave V, Kohli R, Shivakumar SVBY, Kadam D, Gupta A.

Interleukin-6, Interleukin-13 and Interferon-γ as Potential Biomarkers for Treatment Failure in Pulmonary Tuberculosis

Post Date: 
2018-02-15
   |   
Countries: 
Presentation Location: 
New Delhi, India
Event & Convener: 
RePORT India Annual Meeting
Gupte A, Andrade B, Kumar P, Selvaraju S, Lokhande R, Kulkarni V, Paradkar M, Kohli R, Thiru K, Shivakumar SVBY, Gupte N, Babu S, Golub J, Mave V, Chandrasekaran P, Gupta A.

Linezolid Experience Among MDR-TB Patients in Mumbai

Post Date: 
2018-02-15
   |   
Countries: 
Presentation Location: 
New Delhi, India
Event & Convener: 
RePORT India Annual Meeting
Oral Presentation. Tornheim JA, Ganatra S, Deluca A, Banka R, Rodrigues C, Gupta A, Udwadia ZF.

Risk Factors Associated with Unfavorable Outcomes in a Cohort of Pulmonary TB Patients

Post Date: 
2018-02-15
   |   
Countries: 
Presentation Location: 
New Delhi, India
Event & Convener: 
RePORT India Annual Meeting
Oral Presentation. Dhanasekaran K, Chandrasekaran P, Paradkar M, Marinaik SB, Gupte A, Dolla CK, Joseph B, Subramanyam B, Sivaramakrishnan GR, Thiruvengadam K, Gupte N, Rajagopal S, Pradhan N, Selvaraju S, Kulkarni V, Hannah LE, Nayakam R, Suryavanshi N, Shivakumar SVBY, Mave V, Thomas B, Bharadwaj...

Drug Susceptibility of Rifampin-resistant Tuberculosis using Whole Genome Sequencing to Identify Genes of Interest in Pune, India

Post Date: 
2018-02-15
   |   
Clinical Sites: 
   |   
Countries: 
Presentation Location: 
New Delhi, India
Event & Convener: 
RePORT India Annual Meeting
Oral Presentation. Tornheim JA, Madugundu AK, Pradhan N, Bharadwaj R, Mave V, Golub J, Pandey A, Gupta A.

Hyperhomocysteinemia Screening: A Missed Opportunity to Mitigate CVD Risk among Asian Indian HIV-infected Adults?

Post Date: 
2017-12-28
   |   
Clinical Sites: 
   |   
Countries: 
Presentation Location: 
Kolkata, India
Event & Convener: 
AAPI Global Health Summit. American Association of Physicians of Indian Origin
Poster Presentation. Marbaniang I , Sangle S, Kulkarni V, Deshpande P, Shere D, Gupte N, Gupta A, Mave V.

Pages

Matt Robinson, MD

Research Fellow
Baltimore, Maryland
Matthew Robinson, MD, is a research fellow in the Division of Infectious Diseases at Johns Hopkins University School of Medicine. His research focuses on the diagnosis of acute febrile illness and its implication on antimicrobial stewardship and resistance in tropical low- and middle-income countries. Matt is working with Dr. Gupta, Dr. Mave, and Dr. Cosgrove to assess the etiology of febrile illness in patients presenting to a hospital in Pune, India and to determine how diagnosis impacts antibiotic use. He is also working on a CDC-funded project to evaluate the source of antimicrobial...

Dr. Vasudha Belgaumkar

BJGMC-JHU Fogarty HIV-TB Program Trainee
Pune, India
Dr. Vasudha Belgaumkar
Dr.Vasudha has completed her undergraduate medical education from S.B.H. Government Medical College, Dhule,Maharashtra .A meritorious student throughout, she topped her first and final year University examinations. She is presently working as Associate Professor of Dermatology at B.J. Government Medical College, Pune. Having completed her post-graduation in Dermatology, Venereology (including HIV) and Leprology from this premier institute, she has acquired clinical skills as well as an affinity for research.

Matthew Murrill

Baltimore, Maryland
Matthew Murrill
Matthew Murrill is an MD-PhD student in the Department of Epidemiology at the Johns Hopkins Bloomberg School of Public Health. In 2016, he was named an IDSA Education and Research Foundation Medical Scholar. After completing undergraduate studies in chemistry at Maryville College, he moved to Kolkata, India, as a Fulbright-Nehru fellow to research the sources and health effects of groundwater arsenic contamination in Eastern India with the School of Environmental Studies - Jadavpur University. He then worked for Calcutta Kids, a non-governmental organization, to establish a childhood diarrhea...

Rahul Lokhande, MD

BJGMC-JHU Fogarty HIV-TB Program Trainee
Pune, India
Dr. Rahul Lokhande
He is Unit In charge at B J Government Medical college and Sassoon Hospital Pune . He has special Interest in Bronchoscopy and Respiratory Intensive Care Unit of Sassoon Hospital.

Nicky Mehtani, MD

Pune, India
Dr. Mehtani is a second year internal medicine resident at Johns Hopkins Hospital. After studying Global Health Technologies as an undergraduate at Rice University, she pursued a medical degree at Johns Hopkins, where she also earned her MPH at the Bloomberg School of Public Health. As an MPH and medical student, she worked with Dr. Kathleen Page in 2015-2016, analyzing Baltimore City STI surveillance data to help understand the initial effects of the Affordable Care Act on the demand for publicly-funded STD Clinics, and she continued to work on a three-year follow-up study of this issue as a...

Dr. Shilpa Naik

BJGMC-JHU Fogarty HIV-TB Program Trainee
Pune, India
Dr. Shilpa Naik
I am working as an Associate Professor & Unit Incharge since 2009 in the Department of Obstetrics & Gynecology at B.J.Govt Medical College & Sassoon General Hospitals Pune. I have been managing High Risk Obstetrics and has keen interest in Critical Care Obstetrics.

Shivani Mehta

Baltimore, Maryland
Shivani Mehta is a BS/BA candidate (2018) in public health at the Johns Hopkins Krieger School of Arts and Sciences, who is working with Drs. Rupak Shivakoti and Mallika Alexander on Maternal Inflammation, Diet and Gut Microbiome in HIV: Impact on Infant Outcomes. Ms. Mehta spent June and July 2016 at BJGMC in Pune, India, working under Dr. Alexander. Awards 2016 Global Health Established Field Placement Grant 2016 Johns Hopkins Provost Undergradulate Research Award for 2016-17 From Ms. Mehta's Field Report: This week, as the patients come in, I have been sitting with the counselors and...

Erica Orsini, MD

Pune, India
From January 3, 2018 to February 26, 2018, Dr. Orsini worked under Drs. Vidya Mave and Amita Gupta to observe clinical rounds and provide support to the BJGMC Clinical Research Site. She also supported provides the CTRIUMPh substudy entitled “Residual Respiratory Impairment Following Pulmonary TB” and the study entitled “Antimicrobial Use and Diagnosis among Hospitalized Febrile Patients.”

Abhilash Suresh

Baltimore, Maryland
Abhilash Suresh is a BS candidate in biomedical engineering at Johns Hopkins Whiting School of Engineering (2018), who worked with Drs. Akshay Gupte and Shri Vijay Bala Yogendra Shivakumar on the C-TRIUMPH substudy on Residual Respiratory Impairment Following Pulmonary Tuberculosis. During May and June 2016 he conducted a field placement in Chennai, India, at the National Institute for Research in Tuberculosis where he worked under Dr. Shivakumar. Awards 2016 Global Health Established Field Placement Grant From Mr. Suresh's Field Report: This placement opened my eyes to how healthcare works...

Lubaina Arsiwala

Lubaina Arsiwala
Dr. Arsiwala is a Johns Hopkins Masters of Health Science student with a Bachelor in Dental Survey from DY Patil University School of Dentistry, Navi Mumbai, India. She visited BJGMC from June 18, 2018, to August 11, 2018, to provide support to the BJGMC Clinical Research Site. She is working with Dr. Matthew Robinson to support to ongoing studies, including “Antimicrobial Use and Diagnosis among Hospitalized Febrile Patients in Pune, India” and “Prevalence and Risk Factors for Oral Cancer among HIV-Infected Adults.” Dr. Arsiwala received funding for her visit through the Johns Hopkins Global...

Saraniya Tharmarajah

Saraniya Tharmarajah is a public health studies student at the Johns Hopkins Krieger School of Arts and Sciences (2017). During June-July 2015, she conducted a field study placement at the National Institute of Research in Tuberculosis in Chennai, India, where she worked on the C-TRIUMPH lung health substudy. Ms. Tharmarajah is a 2015 recipient of the Global Health Established Field Placement Grant.

Pranay Vishwanath

Baltimore, Maryland
Pranay-Vishwanath
Pranay Vishwanath is a master's candidate in the field of Bioinformatics at Johns Hopkins University in Baltimore, and anticipated to graduate in Fall 2018. He is working with Drs. Amita Gupta and Jeffrey Tornheim, and is focusing on organization of data and generation/streamlining of bioinformatic pipelines for analysis of TB drug resistance assays. He received a bachelor's degree in Biotechnology at the Hong Kong University of Science & Technology in 2016.

Prarthana Vasudevan

Baltimore, Maryland
Prar Vasudevan is an international health graduate student at the Johns Hopkins School of Public Health. In Autumn 2015, she conducted a field placement in Pune, India, at BJGMC under Dr. Vidya Mave, where she worked on the study titled Maternal Inflammation, Diet and Gut Microbiome in HIV: Impact on Infant Outcomes. She is a 2015 recipient of the Global Health Established Field Placement Grant. From Prar Vasudevan's Field Report: At BJMC, I had the opportunity to make rounds in the hospital’s ART Clinic, Labor & Delivery wards, and children’s wards. I was immediately struck by the fact...

Jeff Tornheim, MD, MPH

Infectious Disease Fellow
Baltimore, Maryland
Jeff Tornheim, MD, MPH, is a clinical fellow in the Division of Infectious Disease here at Johns Hopkins University School of Medicine. After completing undergraduate studies in International Development and Economics at Brandeis University he moved to East Africa where he engaged in health system strengthening for returning refugees to South Sudan and worked with the Centers for Disease Control and Prevention (CDC) on the epidemiology of pneumonia and diarrhea in Western Kenya. He completed a joint MD/MPH at Mount Sinai School of Medicine, with his thesis evaluating the impact of water...

Aarti Avinash Kinikar, MD

BJGMC-JHU Fogarty HIV-TB Program Trainee
Pune, India
Education : MBBS (1984); DCH (1988); MD-Paediatrics (1988), DNB-Paediatrics (2003); MRCP-UK (1995). Medical Education- Grant Medical College – Mumbai University, India.

Amit Kale, MS

BJGMC-JHU Fogarty HIV-TB Program Trainee
Pune, India
Dr. Amit Kale
I am working as associate professor in orthopedics. Currently, I am conducting various drug trials for rheumatoid arthritis.

Anita Basavaraj, MD

BJGMC-JHU Fogarty HIV-TB Program Trainee
Pune, India
Dr. Anita Basavaraj
Dr Anita Basavaraj has done her MBBS from Nagpur University with Honors in Surgery (1987). Thereafter she did her MD in Medicine (1990) and her Diplomat of National Board (D.N.B.) in 1992.She has done her post graduate Diploma in geriatric Medicine (P.G.D.G.M.) winning the university Gold Medal by virtue of standing first in the country (2012), which is a distant education venture run by Indira Gandhi National Open University (IGNOU).

Geeta Shrikar Pardeshi, MD

BJGMC-JHU Fogarty HIV-TB Program Trainee
Pune, India
Dr. Geeta Shrikar Pardeshi
I have led research projects related to Reproductive and Child Health, Sanitation and Infectious diseases. As part of the BJGMC JHU Fogarty training program in HIV-TB, I have research interest in TB epidemiology. I am interested in studying the association of co-morbidities with clinical presentation and treatment outcomes in tuberculosis.

Sunita Girish, PhD

BJGMC-JHU Fogarty HIV-TB Program Trainee
Pune, India
Education : Ph.D, Pune University, 2005 (Medical Biochemistry) title “Antioxidant Status in Leprosy.” Overview : How to improve health systems to combat various infectious diseases like Leprosy, Tuberculosis and HIV in developing countries, is a research and policy issue that affects many aspects of public health. My research interests include further to understand molecular level changes in cystic fibrosis which is under diagnosed .My interests also involve innovations in molecular techniques dealing with infectious diseases, help governments in developing countries to improve and modify...

Akshay Gupte, PhD, MBBS, MSPH

Junior Investigator
Akshay Gupte
Akshay Gupte is a junior investigator trained in medicine, clinical research, and global health. He recently completed his doctoral training in the Department of International Health at the Johns Hopkins Bloomberg School of Public Health (JHSPH). His research interests include exploring approaches to host directed adjuvant therapies in tuberculosis (TB) and studying the impact of TB and HIV on lung health of populations. Akshay is leading an Indo-US collaborative study aimed at exploring the impact of TB disease; alone and in combination with smoking, air pollution, HIV and diabetes mellitus...

Pages

Johns Hopkins University Task Force on Women's Academic Careers in Medicine

Post Date: 
2015-01-01
Natasha Chida: Member, 2013-Present Amita Gupta: Member, 2015-Present

Regional Prospective Observational Research for Tuberculosis (RePORT) India Executive Committee

Post Date: 
2014-01-01
US Chair, 2016-Present US Co-chair, 2014-2016

IMPAACT Clinical Trial Network Tuberculosis Scientific Committee

Post Date: 
2012-01-01
Vice Chair Elect, 2012-Present

2012 43rd Union World Conference on Lung Health Conference Committee

Post Date: 
2012-01-01
Abstract Reviewer, 2012

ACTG Clincial Trial Group, Women's Health Inter-Network Scientific Committee

Post Date: 
2011-01-01
Tuberculosis Working Group Member, 2011-2013

ACTG Tuberculosis Transformative Science Group

Post Date: 
2011-01-01
Amita Gupta: Elected Member, 2011-2013 Vidya Mave: Elected Member, 2016-2017

International Union Against Tuberculosis and Lung Disease

Post Date: 
2009-01-01
Amita Gupta, Member, 2009-Present. Maunank Shah, Member, 2009–Present.

National Institutes of Health/National Institute of Child Health and Human Development Study Section

Post Date: 
2008-01-01
Invited RO1 Grant Reviewer, 2008 ZHD1 DSR-K (07) 1- Diagnostic and pharmacokinetic research in pediatric HIV/TB and effects of co-infection on the central nervous system

Johns Hopkins Center for Global Health Grant Review Committee

Post Date: 
2008-01-01
Amita Gupta: Grants Reviewer, 2010 Amita Gupta: Faculty Grants Reviewer, 2008

American Academy of HIV Medicine

Post Date: 
2008-01-01
Amita Gupta: Member, 2008-Present

Pages

Bollinger Installed as Raj & Kamla Gupta Professor of Infectious Diseases

Post Date: 
2018-09-17
Raj and Kamla Gupta and Dr. Robert C. Bollinger
On September 5, CCGHE Director Dr. Robert C. Bollinger was installed as the inaugural recipient of the Raj and Kamla Gupta Professorship in Infectious Diseases, funded by the Ujala Foundation.

Doctor who tackled HIV and other infectious diseases in India honored

Post Date: 
2018-09-11
Source: 
India Abroad
JHU President Ronald Daniels, Raj Gupta, Kamla Gupta Bob Bollinger, Amita Gupta, JH School of Medicine Dean Paul Rothman
India Abroad article highlights the dedication of the Raj and Kamla Gupta Professorship in Infectious Diseases.

Amita Gupta and Sujata Bhatia: Doing a World of Good

Post Date: 
2018-08-29
Source: 
American Institute of Chemical Engineers
Amita Gupta
Amita Gupta is interviewed by AIChE about the intersection of chemical engineering and medicine.

BJGMC Clinical Research Team Exceeds 6,000 Participant Enrollments in 4 Years

Post Date: 
2018-08-03
Group Photo, BJGMC Clinical Research Site, 2016, Pune, India
The Indo-JHU Clinical Research partnership at BJGMC in Pune, India, is now one of the top enrollers among all ACTG research sites internationally.

Isoniazid preventive therapy: do the risks outweigh the benefits in pregnant women with HIV?

Post Date: 
2018-03-13
Source: 
aidsmap
. . . Isoniazid preventive therapy (IPT) during and after pregnancy in women living with HIV on antiretroviral therapy (ART) in tuberculosis (TB) endemic areas in Africa, Asia and Haiti resulted in serious adverse events quite possibly attributable to isoniazid with no significant reduction in TB...

Adverse pregnancy outcomes with isoniazid preventive therapy in HIV

Post Date: 
2018-03-09
Source: 
Infectious Disease Advisor
. . . The safety of IPT in pregnant women with HIV is unknown, especially with regard to its combination with highly active antiretroviral therapy (ART). Amita Gupta, MD, deputy director of the Johns Hopkins University Center for Clinical Global Health Education at the Johns Hopkins University...

No difference in safety for HIV+ pregnant women deferring TB Tx

Post Date: 
2018-03-09
Source: 
MedPage Today
MedPage Today
First randomized clinical trail of IPT in pregnant and postpartum women may suggest need for WHO guideline change.

Preventive TB therapy during pregnancy causes excessive adverse events

Post Date: 
2018-03-08
Source: 
Healio Infectious Disease News
. . . “Identifying ways to prevent TB during pregnancy and the postpartum period is a really important way to address maternal and infant health for a globally important disease such as tuberculosis,” Amita Gupta, MD, MHS, associate professor of medicine and international health and deputy director...

Study Results for IMPAACT P1078 Presented at CROI 2018

Post Date: 
2018-03-07
Source: 
IMPAACT Network News
IMPAACT Network News: Dr. Amita Gupta presented findings at CROI 2018.

One-Month Tuberculosis Prophylaxis as Effective as Nine-Month Regimen for People Living with HIV

Post Date: 
2018-03-05
NIH Logo
The Indo-JHU Clinical Research Partnership participated in this important study that could change TB prevention for people living with HIV.

Tip Sheet: Johns Hopkins Researchers Present at Annual CROI Meeting

Post Date: 
2018-03-01
Newswise — Amita Gupta, M.D., deputy director of the Johns Hopkins University Center for Clinical Global Health Education at the Johns Hopkins University School of Medicine, will present a multicounty study of preventive treatment for tuberculosis (TB) in HIV-infected pregnant and postpartum women—...

2017 Year in Review

Post Date: 
2018-02-19
What a year! Our 2017 Year In Review outlines the most ambitious 365 days we’ve had to date.

Uniting for a Healthier India

Post Date: 
2018-02-14
Uniting India slide
"The Indo-US clinical research & education partnership started with a single NIH grant to study maternal-infant HIV transmission." Now with 76 studies underway, this short film chronicles the history & impact of our work in India.

Celebrating Johns Hopkins Medicine's impact in India

Post Date: 
2017-12-13
Source: 
The Campaign for Johns Hopkins Medicine
In 4 years, the CCGHE has tripled its capacity for conducting research on grave health threats, thanks to strong philanthropic support.

Transforming India from TB Hot Zone to TB Hot Shot

Post Date: 
2017-12-09
Source: 
Indiaspora
Dr. Amita Gupta's invited commentary: Can Indian transform its role in the global TB epidemic?

CCGHE Joins 12-Country UNITAID Effort to Control TB

Post Date: 
2017-11-08
Shorter course to prevent progression of latent TB to active disease is the aim of the effort.

Reduced Level of Disease Possible in India by the Centennial

Post Date: 
2017-08-22
Source: 
India Abroad
India ranks highest in global disease burden. Dr. Amita Gupta weighs in on how to reverse that.

Indo-Hopkins Partnership Seeks Causes of Sepsis in the NICU

Post Date: 
2017-08-10
Sepsis among newborns in the neonatal intensive care unit (NICU) is a big problem in India, and a complex one to untangle.

How can we encourage female leaders in global health?

Post Date: 
2017-08-09
Source: 
Global Health Matters
Fogarty Director Dr. Roger Glass asks why so few women are leading global health centers at med schools or filling other leadership roles.

Health on the Go: Mobile Clinic Delivers TB Services at Point of Need

Post Date: 
2017-03-24
Thanks to Raj and Bharti Shah, CTIS, & the NB Shah Charitable Trust, we are able to reach more people in Maharashtra who need care

Pages